ES2148512T3 - Complejos de inclusion multicomponentes de alta solubilidad que constan de una sustancia farmaceutica acidica, una ciclodextrina y una base. - Google Patents

Complejos de inclusion multicomponentes de alta solubilidad que constan de una sustancia farmaceutica acidica, una ciclodextrina y una base.

Info

Publication number
ES2148512T3
ES2148512T3 ES95916656T ES95916656T ES2148512T3 ES 2148512 T3 ES2148512 T3 ES 2148512T3 ES 95916656 T ES95916656 T ES 95916656T ES 95916656 T ES95916656 T ES 95916656T ES 2148512 T3 ES2148512 T3 ES 2148512T3
Authority
ES
Spain
Prior art keywords
cyclodextrin
base
inclusion complexes
high solubility
pharmaceutical substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95916656T
Other languages
English (en)
Inventor
Paolo Chiesi
Paolo Ventura
Canale Maurizio Del
Maurizio Redenti
Daniela Acerbi
Massimo Pasini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiesi Farmaceutici SpA
Original Assignee
Chiesi Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici SpA filed Critical Chiesi Farmaceutici SpA
Application granted granted Critical
Publication of ES2148512T3 publication Critical patent/ES2148512T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

SE MUESTRAN COMPLEJOS DE INCLUSION MULTICOMPONENTES CARACTERIZADOS POR LA PRESENCIA DE UN MEDICAMENTO ACIDICO, UNA BASE Y UNA CICLODEXTRINA. ESTOS COMPLEJOS TIENE UNA SOLUBILIDAD ESPECIFICA EN EL AGUA.
ES95916656T 1994-04-22 1995-04-13 Complejos de inclusion multicomponentes de alta solubilidad que constan de una sustancia farmaceutica acidica, una ciclodextrina y una base. Expired - Lifetime ES2148512T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI940790A IT1269578B (it) 1994-04-22 1994-04-22 Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo acido, una ciclodestrina e una base.

Publications (1)

Publication Number Publication Date
ES2148512T3 true ES2148512T3 (es) 2000-10-16

Family

ID=11368715

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95916656T Expired - Lifetime ES2148512T3 (es) 1994-04-22 1995-04-13 Complejos de inclusion multicomponentes de alta solubilidad que constan de una sustancia farmaceutica acidica, una ciclodextrina y una base.

Country Status (13)

Country Link
US (1) US5773029A (es)
EP (1) EP0756493B1 (es)
AT (1) ATE194777T1 (es)
AU (1) AU2307695A (es)
CA (1) CA2188388A1 (es)
DE (1) DE69518070T2 (es)
ES (1) ES2148512T3 (es)
HK (1) HK1013627A1 (es)
IL (1) IL113450A (es)
IT (1) IT1269578B (es)
PT (1) PT756493E (es)
WO (1) WO1995028965A1 (es)
ZA (1) ZA953206B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7637296A (en) * 1995-11-14 1997-06-05 Farmarc Nederland Bv Complex of naproxen and beta-cyclodextrin
DE69730902T2 (de) * 1996-05-07 2006-02-23 Pfizer Inc. Verfahren zur Selektion eines Salzes zur Herstellung eines Inklusionskomplexes
UA57734C2 (uk) 1996-05-07 2003-07-15 Пфайзер Інк. Комплекси включення арилгетероциклічних солей
US6383471B1 (en) 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
US6939863B2 (en) 2002-01-04 2005-09-06 Wei-Jan Chen Prevention of atherosclerosis and restenosis
ATE419840T1 (de) 2002-04-09 2009-01-15 Flamel Tech Sa Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen
ATE359827T1 (de) 2002-06-17 2007-05-15 Chiesi Farma Spa Prozess für die vorbereitung von piroxicam: beta- cyclodextrin einschlusskomplexe
ES2322953T3 (es) * 2002-08-20 2009-07-02 Bristol-Myers Squibb Company Formulacion del complejo de aripiprazol y procedimiento.
DE10260873A1 (de) * 2002-12-23 2004-07-15 Beiersdorf Ag Selbstklebende Polymermatrix mit einem Gehalt an Meeresalgenextrakt und Glycerin
US7993654B2 (en) 2002-12-23 2011-08-09 Beiersdorf Ag Self-adhesive polymer matrix containing sea algae extract
DE10260872B4 (de) 2002-12-23 2013-09-26 Beiersdorf Ag Verwendung von gelbildendem Polymer, Wasser, Alkohol und Meeresalgenextrakt zur Einstellung von Elastizität und Haftvermögen selbstklebender kosmetischer Polymermatrices
US20070020578A1 (en) * 2005-07-19 2007-01-25 Scott Robert R Dental curing light having a short wavelength LED and a fluorescing lens for converting wavelength light to curing wavelengths and related method
US20080171687A1 (en) * 2004-09-16 2008-07-17 Abraxis Bioscience, Inc. Compositions And Methods For The Preparation And Administration Of Poorly Water Soluble Drugs
WO2007069274A2 (en) * 2005-11-09 2007-06-21 Torrent Pharmaceuticals Limited Pharmaceutical composition comprising a compound having a catechol moiety and an alkalising agent
FR2914187B1 (fr) * 2007-03-28 2011-01-21 Pf Medicament Complexes d'ibuprofene, de cyclodextrines et d'agents ternaires, et leurs utilisations en pharmaceutique.
PL2434886T3 (pl) 2009-05-29 2020-05-18 Cydex Pharmaceuticals, Inc. Kompozycje do wstrzykiwania melfalanu zawierające pochodną cyklodekstryny i sposoby ich wytwarzania i stosowania
US11020363B2 (en) 2009-05-29 2021-06-01 Cydex Pharmaceuticals, Inc. Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same
CN108210501B (zh) * 2016-12-14 2019-03-08 中国人民解放军军事医学科学院毒物药物研究所 一种磺酰脲类药物的注射用药物组合物及其制备方法
EP4301337A2 (en) * 2021-03-04 2024-01-10 Biogen Chesapeake LLC Low-sorbing glyburide formulation and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196033B (it) * 1984-02-22 1988-11-10 Chiesi Farma Spa Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche
NL8803126A (nl) * 1987-12-22 1989-07-17 Glaxo Group Ltd Waterige preparaten die een piperidinylcyclopentylhepteenzuurderivaat bevatten.
IT1263831B (it) * 1993-01-29 1996-09-04 Paolo Chiesi Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina

Also Published As

Publication number Publication date
ITMI940790A1 (it) 1995-10-22
CA2188388A1 (en) 1995-11-02
HK1013627A1 (en) 1999-09-03
PT756493E (pt) 2000-10-31
IL113450A (en) 1999-05-09
DE69518070T2 (de) 2001-01-11
IT1269578B (it) 1997-04-08
ATE194777T1 (de) 2000-08-15
AU2307695A (en) 1995-11-16
US5773029A (en) 1998-06-30
WO1995028965A1 (en) 1995-11-02
EP0756493B1 (en) 2000-07-19
ZA953206B (en) 1996-01-03
ITMI940790A0 (it) 1994-04-22
EP0756493A1 (en) 1997-02-05
IL113450A0 (en) 1995-07-31
DE69518070D1 (de) 2000-08-24

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