ES2144768T3 - Derivados de bases esfingoides basados en retinoil-amida. - Google Patents
Derivados de bases esfingoides basados en retinoil-amida.Info
- Publication number
- ES2144768T3 ES2144768T3 ES96931002T ES96931002T ES2144768T3 ES 2144768 T3 ES2144768 T3 ES 2144768T3 ES 96931002 T ES96931002 T ES 96931002T ES 96931002 T ES96931002 T ES 96931002T ES 2144768 T3 ES2144768 T3 ES 2144768T3
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- sphingoid bases
- retinoil
- amida
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/18—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A DERIVADOS ACTIVOS DE BASES ESFINGOIDEAS. ESPECIFICAMENTE, LA INVENCION SE REFIERE A DERIVADOS BASADOS EN RETINOILAMIDA DE BASES ESFINGOIDEAS. LA PRESENTE INVENCION DESCRIBE UN METODO PARA OBTENER ESTOS COMPUESTOS. LA INVENCION TAMBIEN SE REFIERE AL USO DE ESTOS COMPUESTOS EN COMPOSICIONES DE USO TOPICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95202369 | 1995-09-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2144768T3 true ES2144768T3 (es) | 2000-06-16 |
Family
ID=8220605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96931002T Expired - Lifetime ES2144768T3 (es) | 1995-09-01 | 1996-09-02 | Derivados de bases esfingoides basados en retinoil-amida. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5792794A (es) |
EP (1) | EP0789686B1 (es) |
JP (1) | JPH10508320A (es) |
KR (1) | KR100556682B1 (es) |
AU (1) | AU6986496A (es) |
BR (1) | BR9606596A (es) |
DE (1) | DE69606514T2 (es) |
ES (1) | ES2144768T3 (es) |
WO (1) | WO1997009307A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5747051A (en) * | 1996-09-27 | 1998-05-05 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an amide of a hydroxy fatty acid and a retinoid |
CN1112916C (zh) * | 1997-12-05 | 2003-07-02 | 科斯莫弗姆有限公司 | 含有游离类鞘氨醇碱和神经酰胺组合的组合物及其用途 |
WO1999050240A1 (en) * | 1998-03-30 | 1999-10-07 | Lg Chemical Ltd. | Polyethoxylated retinamide derivatives and process for preparing the same |
US6372236B1 (en) | 2000-10-18 | 2002-04-16 | Doosan Corporation | Cream composition for skin care |
US6680062B2 (en) | 2001-10-05 | 2004-01-20 | Color Access, Inc. | Anti-irritating rosacea treatment |
DE10255554A1 (de) * | 2002-11-28 | 2004-06-17 | Goldschmidt Ag | Emulgator-Wachs-Gele auf Wasserbasis |
DE102008002410A1 (de) * | 2008-06-13 | 2009-12-17 | Evonik Goldschmidt Gmbh | Enzymatische Synthese von Sphingolipiden |
DE102008002409A1 (de) * | 2008-06-13 | 2009-12-17 | Evonik Goldschmidt Gmbh | Enzymatische Synthese von Sphingolipiden |
ES2832555T3 (es) | 2017-03-27 | 2021-06-10 | Evonik Operations Gmbh | Procedimiento y producto para la preparación de formulaciones con contenido en ceramida |
CN115433100A (zh) * | 2022-08-05 | 2022-12-06 | 深圳市迪克曼生物科技有限公司 | 含共轭羧酸的神经酰胺类化合物及其制备方法和应用 |
CN115894270A (zh) * | 2022-10-10 | 2023-04-04 | 深圳市迪克曼生物科技有限公司 | 一种新型的神经酰胺及其制备方法和应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2081447A1 (en) * | 1970-01-21 | 1971-12-03 | Ici Ltd | Antibacterial bipyridylium salts |
CH529742A (de) * | 1970-02-02 | 1972-10-31 | Hoffmann La Roche | Verfahren zur Herstellung von Vitamin-A-Säureamiden |
DE2843870A1 (de) * | 1978-10-07 | 1980-04-24 | Basf Ag | N-hydroxypropylamide der all-e- und 13-z-retinsaeure |
US5190876A (en) * | 1988-12-27 | 1993-03-02 | Emory University | Method of modifying cellular differentiation and function and compositions therefor |
CA2137001C (en) * | 1992-06-19 | 1999-05-04 | Peter M. Elias | Lipids for epidermal moisturization and repair of barrier function |
US5369030A (en) * | 1992-09-11 | 1994-11-29 | Duke University | Method of inducing cellular differentiations and altering cell phenotype using ceramide analogs |
-
1996
- 1996-09-02 KR KR1019970702867A patent/KR100556682B1/ko not_active IP Right Cessation
- 1996-09-02 BR BR9606596A patent/BR9606596A/pt not_active Application Discontinuation
- 1996-09-02 DE DE69606514T patent/DE69606514T2/de not_active Expired - Fee Related
- 1996-09-02 AU AU69864/96A patent/AU6986496A/en not_active Abandoned
- 1996-09-02 ES ES96931002T patent/ES2144768T3/es not_active Expired - Lifetime
- 1996-09-02 US US08/809,460 patent/US5792794A/en not_active Expired - Fee Related
- 1996-09-02 WO PCT/EP1996/003848 patent/WO1997009307A1/en active IP Right Grant
- 1996-09-02 JP JP9510848A patent/JPH10508320A/ja not_active Ceased
- 1996-09-02 EP EP96931002A patent/EP0789686B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
BR9606596A (pt) | 1997-10-28 |
AU6986496A (en) | 1997-03-27 |
KR100556682B1 (ko) | 2006-06-21 |
EP0789686B1 (en) | 2000-02-02 |
DE69606514D1 (de) | 2000-03-09 |
EP0789686A1 (en) | 1997-08-20 |
US5792794A (en) | 1998-08-11 |
DE69606514T2 (de) | 2000-09-14 |
JPH10508320A (ja) | 1998-08-18 |
KR970707091A (ko) | 1997-12-01 |
WO1997009307A1 (en) | 1997-03-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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