ES2123996T3 - Analogos de 7-etertaxol, uso antineoplasico y composiciones farmaceuticas que los contienen. - Google Patents
Analogos de 7-etertaxol, uso antineoplasico y composiciones farmaceuticas que los contienen.Info
- Publication number
- ES2123996T3 ES2123996T3 ES95923666T ES95923666T ES2123996T3 ES 2123996 T3 ES2123996 T3 ES 2123996T3 ES 95923666 T ES95923666 T ES 95923666T ES 95923666 T ES95923666 T ES 95923666T ES 2123996 T3 ES2123996 T3 ES 2123996T3
- Authority
- ES
- Spain
- Prior art keywords
- cancer
- analogs
- etertaxol
- antineoplasic
- contain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Abstract
ESTA INVENCION PROPORCIONA ANALOGOS DE 7-ETER-TAXOL DE FORMULA (I). LAS COMPOSICIONES DE FORMULA (I) SON UTILES PARA EL TRATAMIENTO DE LOS MISMOS CANCERES PARA LOS QUE SE HA DEMOSTRADO QUE EL TAXOL ES ACTIVO, INCLUYENDO CANCER DE OVARIOS HUMANOS, CANCER DE MAMA, Y MELANOMA MALIGNO ASI COMO CANCER DE PULMON, CANCER GASTRICO, CANCER DE COLON, CANCER DE CABEZA Y CUELLO, Y LEUCEMIA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26817994A | 1994-06-28 | 1994-06-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2123996T3 true ES2123996T3 (es) | 1999-01-16 |
Family
ID=23021820
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95923666T Expired - Lifetime ES2123996T3 (es) | 1994-06-28 | 1995-06-07 | Analogos de 7-etertaxol, uso antineoplasico y composiciones farmaceuticas que los contienen. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0767786B1 (es) |
JP (1) | JPH10502077A (es) |
CN (1) | CN1151740A (es) |
AT (1) | ATE171170T1 (es) |
AU (1) | AU2814595A (es) |
CA (1) | CA2191224A1 (es) |
DE (1) | DE69504843T2 (es) |
DK (1) | DK0767786T3 (es) |
ES (1) | ES2123996T3 (es) |
MX (1) | MX9700026A (es) |
NZ (1) | NZ288802A (es) |
WO (1) | WO1996000724A1 (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2698871B1 (fr) | 1992-12-09 | 1995-02-24 | Rhone Poulenc Rorer Sa | Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
US5973160A (en) | 1992-12-23 | 1999-10-26 | Poss; Michael A. | Methods for the preparation of novel sidechain-bearing taxanes |
US6232477B1 (en) | 1996-03-25 | 2001-05-15 | Aventis Pharma S.A. | Methods of preparing new taxoids and pharmaceutical compositions containing them |
US6040466A (en) * | 1996-03-25 | 2000-03-21 | Rhone Poulenc Rorer Sa | Taxoids, their preparation and pharmaceutical compositions containing them |
US6593482B2 (en) | 1993-02-01 | 2003-07-15 | Aventis Pharma S.A. | Methods for preparing new taxoids and pharmaceutical compositions containing them |
US5847170A (en) * | 1995-03-27 | 1998-12-08 | Rhone-Poulenc Rorer, S.A. | Taxoids, their preparation and pharmaceutical compositions containing them |
MA23823A1 (fr) | 1995-03-27 | 1996-10-01 | Aventis Pharma Sa | Nouveaux taxoides, leur preparation et les compositions qui les contiennent |
US6372780B2 (en) | 1995-03-27 | 2002-04-16 | Aventis Pharma S.A. | Methods of treating cell lines expressing multidrug resistance P-glycoprotein |
DE19605024A1 (de) * | 1996-01-31 | 1997-08-07 | Schering Ag | Neue selektive Taxane, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
CA2253443A1 (en) * | 1996-05-16 | 1997-11-20 | Bristol-Myers Squibb Company | 7-o-methoxymethyl paclitaxel |
US5977386A (en) * | 1996-12-24 | 1999-11-02 | Bristol-Myers Squibb Company | 6-thio-substituted paclitaxels |
US5902822A (en) * | 1997-02-28 | 1999-05-11 | Bristol-Myers Squibb Company | 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels |
US6156789A (en) * | 1998-03-17 | 2000-12-05 | Rhone-Poulenc Rorer S.A. | Method for treating abnormal cell proliferation in the brain |
CA2410632A1 (en) | 2000-06-22 | 2001-12-27 | David S. Garvey | Nitrosated and nitrosylated taxanes, compositions and methods of use |
HUP0302599A3 (en) | 2000-09-22 | 2005-05-30 | Bristol Myers Squibb Co | Method for reducing toxicity of combined chemotherapic compositions |
TW200300416A (en) * | 2001-11-27 | 2003-06-01 | Bristol Myers Squibb Co | Method of synthesizing a paclitaxel derivative |
US8440714B2 (en) * | 2011-06-06 | 2013-05-14 | Arbor Therapeutics, LLC | Acid-labile lipophilic prodrugs of cancer chemotherapeutic agents |
CN102408397B (zh) * | 2011-10-19 | 2014-08-20 | 上海贝美医药科技有限公司 | 紫杉烷类衍生物及其制备方法 |
CN103980232A (zh) * | 2014-06-05 | 2014-08-13 | 北京诺普德医药科技有限公司 | 10-乙酰基多西紫杉醇及其用途 |
CN104086514A (zh) * | 2014-06-19 | 2014-10-08 | 上海应用技术学院 | 紫杉醇衍生物及其制备方法 |
CN107021943B (zh) * | 2016-02-02 | 2020-12-29 | 中国科学院上海药物研究所 | 一类7-epi-巴卡亭III衍生物,及其制备方法和用途 |
CN113698369A (zh) * | 2021-08-31 | 2021-11-26 | 无锡紫杉药业有限公司 | 一种除去卡巴他赛中特定单杂的方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4960790A (en) * | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
IL127597A (en) * | 1994-01-28 | 2003-07-31 | Upjohn Co | Iso-taxol analogs |
-
1995
- 1995-06-07 WO PCT/US1995/006595 patent/WO1996000724A1/en active IP Right Grant
- 1995-06-07 DE DE69504843T patent/DE69504843T2/de not_active Expired - Fee Related
- 1995-06-07 AU AU28145/95A patent/AU2814595A/en not_active Abandoned
- 1995-06-07 ES ES95923666T patent/ES2123996T3/es not_active Expired - Lifetime
- 1995-06-07 AT AT95923666T patent/ATE171170T1/de not_active IP Right Cessation
- 1995-06-07 EP EP95923666A patent/EP0767786B1/en not_active Expired - Lifetime
- 1995-06-07 JP JP8503150A patent/JPH10502077A/ja active Pending
- 1995-06-07 CA CA002191224A patent/CA2191224A1/en not_active Abandoned
- 1995-06-07 DK DK95923666T patent/DK0767786T3/da active
- 1995-06-07 CN CN95193852A patent/CN1151740A/zh active Pending
- 1995-06-07 MX MX9700026A patent/MX9700026A/es unknown
- 1995-06-07 NZ NZ288802A patent/NZ288802A/en unknown
Also Published As
Publication number | Publication date |
---|---|
DK0767786T3 (da) | 1999-06-14 |
JPH10502077A (ja) | 1998-02-24 |
WO1996000724A1 (en) | 1996-01-11 |
EP0767786B1 (en) | 1998-09-16 |
NZ288802A (en) | 1998-05-27 |
DE69504843T2 (de) | 1999-02-11 |
MX9700026A (es) | 1997-04-30 |
DE69504843D1 (de) | 1998-10-22 |
EP0767786A1 (en) | 1997-04-16 |
CN1151740A (zh) | 1997-06-11 |
AU2814595A (en) | 1996-01-25 |
ATE171170T1 (de) | 1998-10-15 |
CA2191224A1 (en) | 1996-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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