ES2120885A1 - New thienopyrimidones with antifungal activity - Google Patents

New thienopyrimidones with antifungal activity

Info

Publication number
ES2120885A1
ES2120885A1 ES09600646A ES9600646A ES2120885A1 ES 2120885 A1 ES2120885 A1 ES 2120885A1 ES 09600646 A ES09600646 A ES 09600646A ES 9600646 A ES9600646 A ES 9600646A ES 2120885 A1 ES2120885 A1 ES 2120885A1
Authority
ES
Spain
Prior art keywords
thienopyrimidones
new
antifungal activity
halogen
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09600646A
Other languages
Spanish (es)
Other versions
ES2120885B1 (en
Inventor
Javier Bartroli
Manuel Anguita
Enric Turmo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Noucor Health SA
Original Assignee
J Uriach y Cia SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES9600646A priority Critical patent/ES2120885B1/en
Application filed by J Uriach y Cia SA filed Critical J Uriach y Cia SA
Priority to PT96929201T priority patent/PT783501E/en
Priority to AT96929201T priority patent/ATE198593T1/en
Priority to EP96929201A priority patent/EP0783501B9/en
Priority to KR1019970701515A priority patent/KR100423590B1/en
Priority to MX9702382A priority patent/MX9702382A/en
Priority to BR9606547A priority patent/BR9606547A/en
Priority to AU68703/96A priority patent/AU6870396A/en
Priority to CA002201477A priority patent/CA2201477C/en
Priority to DK96929201T priority patent/DK0783501T3/en
Priority to JP50725497A priority patent/JP4049207B2/en
Priority to ES96929201T priority patent/ES2153975T3/en
Priority to DE69611512T priority patent/DE69611512T2/en
Priority to PCT/EP1996/003420 priority patent/WO1997005130A1/en
Priority to US08/809,967 priority patent/US5807854A/en
Priority to NO19971470A priority patent/NO312898B1/en
Publication of ES2120885A1 publication Critical patent/ES2120885A1/en
Application granted granted Critical
Publication of ES2120885B1 publication Critical patent/ES2120885B1/en
Priority to GR20010400466T priority patent/GR3035621T3/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Abstract

Compounds of formula I and their salts and solvates in which Ar is a phenyl group optionally substituted by one or more halogen and/or trifluoromethyl groups, R1 is a C1- C4 alkyl group, R2 is hydrogen or a C1-C4 alkyl group, or R1 together with R2 form a C2-C4 polymethylene chain, R3 represents cyano, halogen, C1-C4 haloalkyl or C1-C4 haloalkoxy, and R4 represents hydrogen or C1-C4 alkyl. These compounds are useful as antifungal agents. Processes for obtaining them and pharmaceutical compositions containing them are also described. <IMAGE>
ES9600646A 1995-08-02 1996-03-15 NEW TIENOPIRIMIDONAS WITH ANTIFUNGAL ACTIVITY. Expired - Fee Related ES2120885B1 (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
ES9600646A ES2120885B1 (en) 1996-03-15 1996-03-15 NEW TIENOPIRIMIDONAS WITH ANTIFUNGAL ACTIVITY.
DE69611512T DE69611512T2 (en) 1995-08-02 1996-08-02 PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL EFFECT
EP96929201A EP0783501B9 (en) 1995-08-02 1996-08-02 pyrimidone derivatives with antifungal activity
KR1019970701515A KR100423590B1 (en) 1995-08-02 1996-08-02 New pyrimidone derivatives with antifungal activity
MX9702382A MX9702382A (en) 1995-08-02 1996-08-02 New pyrimidone derivatives with antifungal activity.
BR9606547A BR9606547A (en) 1995-08-02 1996-08-02 New pyrimidone derivatives with fungicidal activity
AU68703/96A AU6870396A (en) 1995-08-02 1996-08-02 New pyrimidone derivatives with antifungal activity
CA002201477A CA2201477C (en) 1995-08-02 1996-08-02 New pyrimidone derivatives with antifungal activity
PT96929201T PT783501E (en) 1995-08-02 1996-08-02 PYRIMIDONE DERIVATIVES WITH ANTIFUNGAL ACTIVITY
JP50725497A JP4049207B2 (en) 1995-08-02 1996-08-02 Novel pyrimidone derivatives with antifungal activity
ES96929201T ES2153975T3 (en) 1995-08-02 1996-08-02 DERIVATIVES OF PIRIMIDONA WITH ANTIFUNGIC ACTIVITY.
AT96929201T ATE198593T1 (en) 1995-08-02 1996-08-02 PYRIMIDONE DERIVATIVES WITH ANTI-FUNGAL EFFECT
PCT/EP1996/003420 WO1997005130A1 (en) 1995-08-02 1996-08-02 New pyrimidone derivatives with antifungal activity
US08/809,967 US5807854A (en) 1995-08-02 1996-08-02 Pyrimidone derivatives with antifungal activity
DK96929201T DK0783501T3 (en) 1995-08-02 1996-08-02 Pyrimidone derivatives with anti-fungal activity
NO19971470A NO312898B1 (en) 1995-08-02 1997-04-01 New pyrimidone derivatives with fungicidal activity
GR20010400466T GR3035621T3 (en) 1995-08-02 2001-03-23 New pyrimidone derivatives with antifungal activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9600646A ES2120885B1 (en) 1996-03-15 1996-03-15 NEW TIENOPIRIMIDONAS WITH ANTIFUNGAL ACTIVITY.

Publications (2)

Publication Number Publication Date
ES2120885A1 true ES2120885A1 (en) 1998-11-01
ES2120885B1 ES2120885B1 (en) 1999-06-16

Family

ID=8294213

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9600646A Expired - Fee Related ES2120885B1 (en) 1995-08-02 1996-03-15 NEW TIENOPIRIMIDONAS WITH ANTIFUNGAL ACTIVITY.

Country Status (1)

Country Link
ES (1) ES2120885B1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2024336A6 (en) * 1990-10-16 1992-02-16 Uriach & Cia Sa J Process for obtaining new thiazole derivatives
EP0567982A1 (en) * 1992-04-28 1993-11-03 Takeda Chemical Industries, Ltd. Azole compounds, their production and use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2024336A6 (en) * 1990-10-16 1992-02-16 Uriach & Cia Sa J Process for obtaining new thiazole derivatives
EP0567982A1 (en) * 1992-04-28 1993-11-03 Takeda Chemical Industries, Ltd. Azole compounds, their production and use

Also Published As

Publication number Publication date
ES2120885B1 (en) 1999-06-16

Similar Documents

Publication Publication Date Title
BG104248A (en) Benzamidoxim derivatives, intermediate products and methods for preparing and using them as fungicides
ES2161382T3 (en) DERIVATIVES OF PIRAZOL, PROCEDURE FOR THE PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
MX9700130A (en) 2-[1&#39;,2&#39;,4&#39;-triazol-3&#39;-yloxymethylene]-anilides and their use as pest-control agents.
AR061492A2 (en) PROCEDURE FOR THE PREPARATION OF INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF 5-AMINO-1-ARIL-3-CIANO PIRAZOLES
PT918776E (en) TOTAL SYNTHESIS OF ANTITUMAL ACILFULVENOS
DE69925472D1 (en) BENZOHETEROCYCLIC DISTAMYCINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS ANTITUMUM AGENT
AR002761A1 (en) A COMPOUND DERIVED FROM TRIAZOLE, ITS USE, A PHARMACEUTICAL COMPOSITION THAT CONTAINS IT, A METHOD OF TREATMENT OR PREVENTION OF A FUNGAL INFECTION IN A HUMAN PATIENT THROUGH SUCH A COMPOUND OR COMPOSITION, AND INTERMEDIATE PROCEDURE AND COMPOUNDS TO PREPARE IT.
DK209487D0 (en) SILAND DERIVATIVES, PROCEDURES FOR THEIR PREPARATION, MENTALS CONTAINING THESE RELATIONSHIPS AND THEIR USE AS PESTICIDES
HU9501585D0 (en) Azoxycyanobenzene-derivatives, process for their preparation, fungicidal compositions containing them
PE20021018A1 (en) DERIVATIVES OF ß - CARBOLINE
ES2089041T5 (en) SUBSTITUTED PIRIDINASULFONAMIDE COMPOUNDS, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND PROCEDURE FOR THEIR PREPARATION.
PL290676A1 (en) Method of obtaining novel derivatives of 2-aminoalkyl-5-diaryl-alkyl-1.3-dioxane
ES2183036T3 (en) 2,2 &#39;- DISUSTITUIDOS-FERROCENOS 2,2`-DISUSTITUIDOS and 1-PHOSPHINO-FERROCENOS 1`, 2-DISUSTITUIDOS, PROCEDURE FOR THEIR PREPARATION, ITS USE, AS WELL AS COMPLEXES OF TRANSITION METALS CONTAINING THEM.
DK1471059T3 (en) 2,4,6-tris (dinopentyl-4&#39;-aminobenzalmalonate) -s-triazine, photoprotective cosmetic compositions containing this compound and use of said compound
DK0395175T3 (en) thiazole
ES2120885A1 (en) New thienopyrimidones with antifungal activity
DK0847384T3 (en) Carbamoylcarboxylic acid amides
DE69900297T2 (en) Acaricidal and insecticidal, substituted pyrimidines and process for their preparation
PT96557A (en) METHOD FOR PREPARING ERGOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
TW429147B (en) Pharmaceutical composition for the treatment of CNS disorders
UA70917C2 (en) INCECTICIDAL COMPOUNDS OF oxadiazine
DK0765322T3 (en) Indole derivatives as pro-drugs for 5-HT1-like receptor agonists
ES2107376A1 (en) New pyrimidone derivatives having antifungal activity
ES2192342T3 (en) 2- (2,6-DIOXO-3-FLUOROPIPERIDIN-3-IL) -ISOINDOLINAS REPLACED AND ITS USE TO REDUCE TNFALFA LEVELS.
ATE148462T1 (en) ISOXAZOLE DERIVATIVES AS LIGHT PROTECTIVE AGENTS

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 19981101

Kind code of ref document: A1

Effective date: 19981101

FD1A Patent lapsed

Effective date: 20020404