ES2119945T3 - Derivados de indol, sus sales y agentes para el tratamiento de las enfermedades cardiacas que los contienen. - Google Patents
Derivados de indol, sus sales y agentes para el tratamiento de las enfermedades cardiacas que los contienen.Info
- Publication number
- ES2119945T3 ES2119945T3 ES94117102T ES94117102T ES2119945T3 ES 2119945 T3 ES2119945 T3 ES 2119945T3 ES 94117102 T ES94117102 T ES 94117102T ES 94117102 T ES94117102 T ES 94117102T ES 2119945 T3 ES2119945 T3 ES 2119945T3
- Authority
- ES
- Spain
- Prior art keywords
- chem
- action
- indol
- derivatives
- salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
UN DERIVADO DE INDOL REPRESENTADO POR LA FORMULA (1), EN LA QUE A ES UN GRUPO O EN DONDE R10 ES HIDROGENO O ALQUILO INFERIOR, LAS LINEAS DE PUNTOS PUEDEN SER OPCIONALMENTE REENVIADAS Y DE R1 A R9 REPRESENTAN VARIOS GRUPOS SUSTITUIDORES. EL COMPUESTO (1) PRESENTA UNA ACCION INOTROPICA POSITIVA EN EL MUSCULO CARDIACO, UNA ACCION ANTIARRITMICA Y UNA ACCION VASOLITADORA SIN AUMENTAR EL RITMO DEL CORAZON. UN AGENTE TERAPEUTICO PARA UNA AFECCION CARDIACA QUE CONTENGA ESTE COMPUESTO COMO COMPONENTE EFECTIVO ES EXTREMADAMENTE EFECTIVO PARA EL TRATAMIENTO DE FALLOS CARDIACOS Y DE LA ARRITMIA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP27177093 | 1993-10-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2119945T3 true ES2119945T3 (es) | 1998-10-16 |
Family
ID=17504610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94117102T Expired - Lifetime ES2119945T3 (es) | 1993-10-29 | 1994-10-28 | Derivados de indol, sus sales y agentes para el tratamiento de las enfermedades cardiacas que los contienen. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5510366A (es) |
EP (1) | EP0653426B1 (es) |
KR (1) | KR100327264B1 (es) |
AT (1) | ATE168690T1 (es) |
CA (1) | CA2134608C (es) |
DE (1) | DE69411852T2 (es) |
DK (1) | DK0653426T3 (es) |
ES (1) | ES2119945T3 (es) |
SI (1) | SI0653426T1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6391005B1 (en) | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
WO2004045534A2 (en) * | 2002-11-15 | 2004-06-03 | Galileo Pharmaceuticals, Inc. | Chroman derivatives for the reduction of inflammation symptoms |
GT200500296A (es) * | 2004-10-21 | 2006-10-02 | Sintesis asimetrica de derivados del dehidrobenzofurano | |
TWI435729B (zh) | 2005-11-09 | 2014-05-01 | Combinatorx Inc | 治療病症之方法,組合物及套組 |
EP2804603A1 (en) | 2012-01-10 | 2014-11-26 | President and Fellows of Harvard College | Beta-cell replication promoting compounds and methods of their use |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1159459A (en) * | 1980-12-11 | 1983-12-27 | Andre A. Asselin | 6,7,8,9-tetrahydro-3h-benz¬e| indolamine derivatives |
DE3525564A1 (de) * | 1985-07-15 | 1987-02-05 | Schering Ag | Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
CA2075057A1 (en) * | 1990-03-15 | 1991-09-16 | Pharmacia & Upjohn Company Llc | Therapeutically useful heterocyclic indole compounds |
-
1994
- 1994-10-21 KR KR1019940026999A patent/KR100327264B1/ko not_active IP Right Cessation
- 1994-10-28 EP EP94117102A patent/EP0653426B1/en not_active Expired - Lifetime
- 1994-10-28 SI SI9430179T patent/SI0653426T1/xx unknown
- 1994-10-28 ES ES94117102T patent/ES2119945T3/es not_active Expired - Lifetime
- 1994-10-28 US US08/330,670 patent/US5510366A/en not_active Expired - Fee Related
- 1994-10-28 CA CA002134608A patent/CA2134608C/en not_active Expired - Fee Related
- 1994-10-28 DE DE69411852T patent/DE69411852T2/de not_active Expired - Fee Related
- 1994-10-28 AT AT94117102T patent/ATE168690T1/de not_active IP Right Cessation
- 1994-10-28 DK DK94117102T patent/DK0653426T3/da active
Also Published As
Publication number | Publication date |
---|---|
DE69411852T2 (de) | 1998-12-03 |
CA2134608A1 (en) | 1995-04-30 |
SI0653426T1 (en) | 1998-12-31 |
ATE168690T1 (de) | 1998-08-15 |
DK0653426T3 (da) | 1998-10-26 |
KR950011446A (ko) | 1995-05-15 |
EP0653426A1 (en) | 1995-05-17 |
KR100327264B1 (ko) | 2002-07-02 |
EP0653426B1 (en) | 1998-07-22 |
US5510366A (en) | 1996-04-23 |
CA2134608C (en) | 2004-12-07 |
DE69411852D1 (de) | 1998-08-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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