ES2118343T3 - Nuevos derivados de 2-(1h)-quinoleinona, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. - Google Patents
Nuevos derivados de 2-(1h)-quinoleinona, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.Info
- Publication number
- ES2118343T3 ES2118343T3 ES94401926T ES94401926T ES2118343T3 ES 2118343 T3 ES2118343 T3 ES 2118343T3 ES 94401926 T ES94401926 T ES 94401926T ES 94401926 T ES94401926 T ES 94401926T ES 2118343 T3 ES2118343 T3 ES 2118343T3
- Authority
- ES
- Spain
- Prior art keywords
- substituted
- branched
- linear
- unsubstituted
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/5765—Six-membered rings condensed with carbocyclic rings or carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/60—Quinoline or hydrogenated quinoline ring systems
Abstract
COMPUESTOS DE FORMULA (I): DONDE: R1,R2 Y R3 IDENTICOS O DIFERENTES, REPRESENTAN UN ATOMO DE HIDROGENO, DE HALOGENO O DE UN GRUPO ALQUILO, NITRO, CIANO O AMINOSULFONILO, O BIEN CUANDO DOS DE ELLOS ESTAN SITUADOS SOBRE CARBONOS ADYACENTES, FORMAN CON LOS ATOMOS DE CARBONO A LOS QUE ESTAN UNIDOS UN CICLO CICLOALQUILO (C3 UIDO, R4 REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO (C1 O UN GRUPO DONDE R6 Y R7 IDENTICOS O DIFERENTES, REPRESENTAN UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO (C1 FICADO SUSTITUIDO O NO SUSTITUIDO, R5 REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO HIDROXI, ALCOXI (C1 C6) LINEAL O RAMIFICADO, FENOXI, MERCAPTO, ALQUILTIO (C1 STITUIDO NO SUSTITUIDO, FENILO SUSTITUIDO O NO SUSTITUIDO, AMINO SUSTITUIDO O NO SUSTITUIDO, O UN GRUPO DONDE R6 Y R7 SON TAL COMO SE DEFINEN ANTERIORMENTE, SUS ISOMEROS ASI COMO SUS SALES DE ADICION A UN ACIDO O A UNA BASE FARMACEUTICAMENTE ACEPTABLE. MEDICAMENTOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9310379A FR2709489B1 (fr) | 1993-08-31 | 1993-08-31 | Nouveaux dérivés de 2-(1H)-quinoléinone, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2118343T3 true ES2118343T3 (es) | 1998-09-16 |
Family
ID=9450460
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94401926T Expired - Lifetime ES2118343T3 (es) | 1993-08-31 | 1994-08-31 | Nuevos derivados de 2-(1h)-quinoleinona, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. |
Country Status (12)
Country | Link |
---|---|
US (2) | US5536709A (es) |
EP (1) | EP0640612B1 (es) |
JP (1) | JP2672262B2 (es) |
AT (1) | ATE165362T1 (es) |
AU (1) | AU676348B2 (es) |
CA (1) | CA2117600A1 (es) |
DE (1) | DE69409734T2 (es) |
DK (1) | DK0640612T3 (es) |
ES (1) | ES2118343T3 (es) |
FR (1) | FR2709489B1 (es) |
NZ (1) | NZ264338A (es) |
ZA (1) | ZA946659B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000309585A (ja) * | 1999-02-26 | 2000-11-07 | Kyorin Pharmaceut Co Ltd | 6−置換ヘテロキノリンカルボン酸誘導体とその付加塩及びそれらの製造方法 |
FR2805261A1 (fr) * | 2000-02-18 | 2001-08-24 | Adir | Nouveaux derives d'acides 6-amino ou 6-hydrazinosulfonyl-3- quinolinyl phosphoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2805262A1 (fr) * | 2000-02-18 | 2001-08-24 | Adir | Nouveaux derives d'acides aryle ou heteroaryle quinolinyl phosphoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2805260A1 (fr) * | 2000-02-18 | 2001-08-24 | Adir | Nouveaux derives d'acides 6-sulfamoyl-3-quinolinyl phosphoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
TWI366565B (en) | 2007-06-06 | 2012-06-21 | Otsuka Pharma Co Ltd | Quinolone compound and pharmaceutical composition |
CL2008003065A1 (es) * | 2007-10-16 | 2009-07-17 | Janssen Pharmaceutica Nv | Proceso para preparar un compuesto derivado de acido carbamoil-fosfonico o del acido carbamoil-fosfinico. |
WO2012164085A1 (en) | 2011-06-03 | 2012-12-06 | Merz Pharma Gmbh & Co. Kgaa | Glycine b antagonists |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4124588A (en) * | 1976-03-01 | 1978-11-07 | Sandoz, Inc. | 4-Hydroxy-quinolin-2-one-3-phosphonic acid esters |
US4093637A (en) * | 1977-01-31 | 1978-06-06 | The United States Of America As Represented By The Secretary Of Agriculture | Alkyl 9,9(10,10)-bis(acyloxymethyl)octadecanoates as primary plasticizers for polyvinylchloride |
US4906621A (en) * | 1985-05-24 | 1990-03-06 | Ciba-Geigy Corporation | Certain 2-carboxypiperidyl-alkylene phosphonic acids and esters thereof useful for the treatment of disorders responsive to N-methyl-D-aspartate receptor blockade |
FR2683818B1 (fr) * | 1991-11-14 | 1993-12-31 | Adir Cie | Nouveaux derives de 3-sulfonylamino-2-(1h)-quinoleinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
IS4233A (is) * | 1993-12-22 | 1995-06-23 | Astra Aktiebolag | Misleit hringtengd efnasambönd |
-
1993
- 1993-08-31 FR FR9310379A patent/FR2709489B1/fr not_active Expired - Fee Related
-
1994
- 1994-08-29 CA CA002117600A patent/CA2117600A1/fr not_active Abandoned
- 1994-08-29 AU AU71520/94A patent/AU676348B2/en not_active Ceased
- 1994-08-30 US US08/297,793 patent/US5536709A/en not_active Expired - Fee Related
- 1994-08-30 JP JP6205464A patent/JP2672262B2/ja not_active Expired - Fee Related
- 1994-08-30 NZ NZ264338A patent/NZ264338A/en unknown
- 1994-08-31 DE DE69409734T patent/DE69409734T2/de not_active Expired - Fee Related
- 1994-08-31 EP EP94401926A patent/EP0640612B1/fr not_active Expired - Lifetime
- 1994-08-31 ZA ZA946659A patent/ZA946659B/xx unknown
- 1994-08-31 AT AT94401926T patent/ATE165362T1/de not_active IP Right Cessation
- 1994-08-31 ES ES94401926T patent/ES2118343T3/es not_active Expired - Lifetime
- 1994-08-31 DK DK94401926T patent/DK0640612T3/da active
-
1995
- 1995-07-10 US US08/499,946 patent/US5646132A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5536709A (en) | 1996-07-16 |
DE69409734D1 (de) | 1998-05-28 |
FR2709489B1 (fr) | 1995-10-20 |
FR2709489A1 (fr) | 1995-03-10 |
AU7152094A (en) | 1995-03-16 |
NZ264338A (en) | 1995-10-26 |
EP0640612A1 (fr) | 1995-03-01 |
EP0640612B1 (fr) | 1998-04-22 |
ZA946659B (en) | 1995-04-20 |
JPH07149778A (ja) | 1995-06-13 |
DK0640612T3 (da) | 1999-02-15 |
US5646132A (en) | 1997-07-08 |
AU676348B2 (en) | 1997-03-06 |
DE69409734T2 (de) | 1998-11-12 |
CA2117600A1 (fr) | 1995-03-01 |
ATE165362T1 (de) | 1998-05-15 |
JP2672262B2 (ja) | 1997-11-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK57197A (en) | Naphthalene derivatives procedure for their preparation and pharmaceutical compositions containing them | |
MX9204622A (es) | Nuevos derivados de 3,5-di-tert-butil-4-hidroxifenilo, procedimiento para su preparacion y composicion farmaceutica que los contiene. | |
SE7601207L (sv) | Acetylenderivat av acetyleniska aminosyror | |
DK71780A (da) | Fremgangsmaade til fremstilling af difenylhydantoinderivater | |
ES2064156T3 (es) | Derivados de 3-sulfonil-amino-2-(1h)-quinoleinona, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
ES2063471T3 (es) | Nuevos derivados de guanidina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
ES2118343T3 (es) | Nuevos derivados de 2-(1h)-quinoleinona, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
NO912298D0 (no) | Fremgangsmaate for fremstilling av terapeutisk aktive 1,3-dioksanderivater. | |
ES2119106T3 (es) | Nuevos benzo-espiro-alquenos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
NO890440L (no) | Fremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater. | |
ATE176906T1 (de) | Benzolactam-derivate | |
DE69005318T2 (de) | 1,8-Benzonaphthyridinderivate, ihre Herstellung und diese enthaltende Zusammensetzungen. | |
DE69301639D1 (de) | Tetrahydronaphtalenderivate, ihre Herstellung und ihre therapeutische Verwendung | |
ES2060095T3 (es) | Nuevas imidazobenzodiazepinas y sus sales, procedimiento de preparacion, aplicacion como medicamentos y composiciones que los contienen. | |
SE8500963D0 (sv) | Nitraminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 640612 Country of ref document: ES |