ES2116599T3 - Procedimiento de produccion de derivado de acido carboxilico. - Google Patents

Procedimiento de produccion de derivado de acido carboxilico.

Info

Publication number
ES2116599T3
ES2116599T3 ES94919838T ES94919838T ES2116599T3 ES 2116599 T3 ES2116599 T3 ES 2116599T3 ES 94919838 T ES94919838 T ES 94919838T ES 94919838 T ES94919838 T ES 94919838T ES 2116599 T3 ES2116599 T3 ES 2116599T3
Authority
ES
Spain
Prior art keywords
reacting
acid
give
alpha
nitrile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94919838T
Other languages
English (en)
Inventor
Akira Takase
Hiroyuki Kai
Moriyasu Masui
Katuhisa Masumoto
Akihiko Nakamura
Yujiro Kiyoshima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Sumitomo Chemical Co Ltd
Original Assignee
Shionogi and Co Ltd
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd, Sumitomo Chemical Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of ES2116599T3 publication Critical patent/ES2116599T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/12—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reactions not involving the formation of oxyimino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/48—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN PROCESO PARA OBTENER UN DERIVADO DEL ACIDO CARBOXILICO, REPRESENTADO POR LA FORMULA GENERAL [VIII], (EN LA QUE R1, R2, R3 Y L SON CADA UNO CONFORME A LO DEFINIDO EN LA MEMORIA), QUE COMPRENDE LA REACCION DE UN HALURO DE BENCILO CON UN COMPUESTO DE CIANO, PARA OBTENER UN FENILACETONITRILO, REACCIONANDO EL NITRILO CON UN NITRITO DE ALQUILO, EN PRESENCIA DE UNA BASE, PARA DAR UN HIDROXIIMINOFENILACETONITRILO, REACCIONANDO EL NITRILO HIDROXI CON UN AGENTE ALQUILIZANTE, PARA OBTENER UN ALCOXIIMINOFENILACETONITRILO, HIDROLIZANDO EL NITRILO DE ALCOXI EN PRESENCIA DE UNA BASE, OPCIONALMENTE DESPUES DE LA HIDRATACION Y TRATAMIENTO ACIDO, PARA DAR UN ACIDO - ALCOXIIMINOFENILACETICO, Y FINALMENTE RACCIONANDO EL ACIDO CON UN AGENTE DE HALOGENACION, O CONVIRTIENDO EL ACIDO EN UNA SAL METALICA CORRESPONDIENTE, Y REACCIONANDO LA SAL CON UN AGENTE ALQUILIZANTE, O REACCIONANDO EL ACIDO CON UN ALCOHOL INFERIOR, EN PRESENCIA DE UN CATALIZADOR ACIDICO. DE CONFORMIDAD CON ESTE PROCESO, PUEDEN REALIZARSE LASREACCIONES MEDIANTE FASES RESPECTIVAS, EN CONDICIONES POCO RIGUROSAS, Y EL DERIVADO DE REFERENCIA [VIII] PUEDE PRODUCIRSE SIN RECURRIR A EQUIPO DE VAPOR A GRAN PRESION, EQUIPO MEDIO DE CALOR A TEMPERATURA ELEVADA, NEVERA, Y ASI SUCESIVAMENTE. ADEMAS, ESTE PROCESO ES CONVENIENTE PORQUE CON UN DISOLVENTE UNICO BASTA, SIN NECESIDAD DE USAR VARIOS DISOLVENTES DE CONFORMIDAD CON LAS FASES RESPECTIVAS.
ES94919838T 1993-07-02 1994-07-01 Procedimiento de produccion de derivado de acido carboxilico. Expired - Lifetime ES2116599T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP16471193 1993-07-02
JP16471293 1993-07-02
JP16471093 1993-07-02
JP2049794 1994-02-17

Publications (1)

Publication Number Publication Date
ES2116599T3 true ES2116599T3 (es) 1998-07-16

Family

ID=27457395

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94919838T Expired - Lifetime ES2116599T3 (es) 1993-07-02 1994-07-01 Procedimiento de produccion de derivado de acido carboxilico.

Country Status (8)

Country Link
US (1) US5510506A (es)
EP (1) EP0658541B1 (es)
AT (1) ATE166340T1 (es)
BR (1) BR9405498A (es)
DE (1) DE69410414T2 (es)
DK (1) DK0658541T3 (es)
ES (1) ES2116599T3 (es)
WO (1) WO1995001328A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4443641A1 (de) * 1994-12-08 1996-06-13 Bayer Ag Substituierte Carbonsäureamide
US6727277B1 (en) 2002-11-12 2004-04-27 Kansas State University Research Foundation Compounds affecting cholesterol absorption
CN109651190A (zh) * 2018-12-28 2019-04-19 京博农化科技有限公司 一种醚菌酯的合成方法
CN115819215A (zh) * 2022-11-08 2023-03-21 广东省科学院化工研究所 一种路易斯酸催化合成羧酸衍生物的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1110460B (it) * 1977-03-02 1985-12-23 Ciba Geigy Ag Prodotti che favoriscono la crescita delle piante e prodotti che proteggono le piante a base di eteri di ossime e di esteri di ossime loro preparazione e loro impiego
DE2825565A1 (de) * 1978-06-10 1979-12-20 Bayer Ag Verfahren zur herstellung von 2-oximinophenylacetonitril
DE2927117A1 (de) * 1979-07-05 1981-01-08 Basf Ag Verfahren zur herstellung von o-substituierten ketoximen
DE4030038A1 (de) * 1990-09-22 1992-03-26 Basf Ag Ortho-substituierte phenylessigsaeureamide
ES2107923T3 (es) * 1990-12-31 1997-12-01 Basf Ag Procedimiento para la obtencion de cianuros de benzoilo o-substituidos.
DE4203170A1 (de) * 1992-02-05 1993-08-12 Basf Ag Verfahren zur herstellung von e-oximethern von phenylglyoxylsaeureestern
CA2102078A1 (en) * 1992-11-02 1994-05-03 Akira Takase A process for producing (e)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor

Also Published As

Publication number Publication date
DE69410414D1 (de) 1998-06-25
EP0658541A1 (en) 1995-06-21
US5510506A (en) 1996-04-23
DK0658541T3 (da) 1998-10-19
EP0658541A4 (en) 1996-02-07
EP0658541B1 (en) 1998-05-20
WO1995001328A1 (fr) 1995-01-12
ATE166340T1 (de) 1998-06-15
BR9405498A (pt) 1999-06-15
DE69410414T2 (de) 1998-12-10

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