ES2115208T3 - Proteina de la superficie celular de brevibacterium lactofermentum. - Google Patents
Proteina de la superficie celular de brevibacterium lactofermentum.Info
- Publication number
- ES2115208T3 ES2115208T3 ES94904315T ES94904315T ES2115208T3 ES 2115208 T3 ES2115208 T3 ES 2115208T3 ES 94904315 T ES94904315 T ES 94904315T ES 94904315 T ES94904315 T ES 94904315T ES 2115208 T3 ES2115208 T3 ES 2115208T3
- Authority
- ES
- Spain
- Prior art keywords
- brevibacterium lactofermentum
- protein
- transformant
- image
- cellular surface
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/345—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Brevibacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
SE PREPARA UN TRANSFORMADOR MEDIANTE LA INTRODUCCION EN UN CORINEFORME DE UN FRAGMENTO DE ADN QUE CONTIENE UN GEN CODIFICADO PARA UNA NUEVA PROTEINA DEL CORTEX CELULAR ORIGINADA EN BREVIBACTERIUM LACTOFERMENTUM Y QUE TIENE LAS DOS SECUENCIAS SIGUIENTES EN SU MOLECULA Y UN PESO MOLECULAR DE APROXIMADAMENTE 63,000 D: (1) THR-LEU-ARG-GLN-HIS-TYR-SER-SER-LEU_ILE-PRO-ASN-LEUPHE-ILE-ALA-ALA-VAL-GLY-ASN-ILE-ASN-GLU-LEU-ASN-ASN-ALA-ASP-GLN-ALAALA-ARG-GLU-LEU-PHE-LEU-ASP-TRP-ASP-THR, (2) ASN-LYS-THR-ASP-PHE-ALAGLU-ILE-GLU-LEU-TYR-ASP-VAL-LEU-TYR-THR-ASP-ALA-ASP-ILE-SER-GLY-ASPALA-PRO-LEU-LEU-ALA-PRO-ALA-TYR-LYS. ESTE TRANSFORMANTE O UNA ESTIRPE DEFICIENTE EN LA NUEVA PROTEINA DEL CORTEX DE CELULA, QUE HA SIDO RECIENTAMENTE PREPARADO, SE UTILIZA PARA PRODUCIR SUBSTANCIAS VALIOSAS QUE INCLUYEN L-AMINOACIDOS POR EL METODO DE FERMENTACION DE L-AMINOACIDO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP406993 | 1993-01-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2115208T3 true ES2115208T3 (es) | 1998-06-16 |
Family
ID=11574537
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94904315T Expired - Lifetime ES2115208T3 (es) | 1993-01-13 | 1994-01-13 | Proteina de la superficie celular de brevibacterium lactofermentum. |
Country Status (10)
Country | Link |
---|---|
US (2) | US5547864A (es) |
EP (1) | EP0644200B1 (es) |
JP (1) | JP3541385B2 (es) |
KR (1) | KR0164235B1 (es) |
CN (2) | CN1036850C (es) |
AT (1) | ATE165606T1 (es) |
BR (1) | BR9403528A (es) |
DE (1) | DE69409895T2 (es) |
ES (1) | ES2115208T3 (es) |
WO (1) | WO1994015963A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19903345A1 (de) * | 1999-01-28 | 2000-08-03 | Werner Lubitz | Kompartimentierung von rekombinanten Polypeptiden in Wirtszellen |
US6927046B1 (en) * | 1999-12-30 | 2005-08-09 | Archer-Daniels-Midland Company | Increased lysine production by gene amplification using coryneform bacteria |
RU2264463C2 (ru) * | 2001-03-30 | 2005-11-20 | Адзиномото Ко., Инк. | Способ секреторной продукции белка |
CN100401896C (zh) * | 2002-12-09 | 2008-07-16 | 儿童医院医疗中心 | 诊断和治疗间质性肺病的方法 |
US20040224340A1 (en) * | 2003-04-21 | 2004-11-11 | Filutowicz Marcin S. | Displacing a plasmid in a bacterial population |
WO2014126260A1 (ja) * | 2013-02-18 | 2014-08-21 | 味の素株式会社 | タンパク質の沈殿による製造方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50126877A (es) * | 1974-03-28 | 1975-10-06 | ||
JPS5722558A (en) * | 1980-07-16 | 1982-02-05 | Mitsubishi Chem Ind Ltd | Formwise measuring device for extreme trace of nitrogen |
JPS57134500A (en) * | 1981-02-12 | 1982-08-19 | Kyowa Hakko Kogyo Co Ltd | Plasmid pcg1 |
JPS57183799A (en) * | 1981-04-17 | 1982-11-12 | Kyowa Hakko Kogyo Co Ltd | Novel plasmid |
JPS5835197A (ja) * | 1981-08-26 | 1983-03-01 | Kyowa Hakko Kogyo Co Ltd | プラスミドpcg2 |
JPS5867699A (ja) * | 1981-10-16 | 1983-04-22 | Ajinomoto Co Inc | プラスミド |
JPS5877895A (ja) * | 1981-11-02 | 1983-05-11 | Ajinomoto Co Inc | プラスミドphm1519 |
JPS58192900A (ja) * | 1982-05-04 | 1983-11-10 | Ajinomoto Co Inc | 複合プラスミド |
JPH0691829B2 (ja) * | 1983-08-24 | 1994-11-16 | 味の素株式会社 | 発酵法によるl―リジンの製造法 |
JPH06102029B2 (ja) * | 1984-07-31 | 1994-12-14 | 味の素株式会社 | L−トリプトフアンの製造法 |
JPH07112431B2 (ja) * | 1985-09-06 | 1995-12-06 | 味の素株式会社 | 遺伝子発現調節法 |
JPH06102024B2 (ja) * | 1986-04-16 | 1994-12-14 | 味の素株式会社 | 新規プロモーター及び該プロモーターを用いた遺伝子発現方法 |
FR2627508B1 (fr) * | 1988-02-22 | 1990-10-05 | Eurolysine | Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede |
JPH02207791A (ja) * | 1989-02-07 | 1990-08-17 | Ajinomoto Co Inc | 微生物の形質転換法 |
JPH07108228B2 (ja) * | 1990-10-15 | 1995-11-22 | 味の素株式会社 | 温度感受性プラスミド |
JPH04271780A (ja) * | 1991-02-26 | 1992-09-28 | Ajinomoto Co Inc | リコンビナントリパーゼ |
WO1993003158A1 (fr) * | 1991-07-30 | 1993-02-18 | Orsan | Systeme d'expression et de secretion de proteines utilisables en particulier chez les corynebacteries |
-
1994
- 1994-01-13 KR KR1019940703193A patent/KR0164235B1/ko not_active IP Right Cessation
- 1994-01-13 WO PCT/JP1994/000039 patent/WO1994015963A1/ja active IP Right Grant
- 1994-01-13 AT AT94904315T patent/ATE165606T1/de not_active IP Right Cessation
- 1994-01-13 JP JP51400194A patent/JP3541385B2/ja not_active Expired - Lifetime
- 1994-01-13 US US08/295,670 patent/US5547864A/en not_active Expired - Lifetime
- 1994-01-13 ES ES94904315T patent/ES2115208T3/es not_active Expired - Lifetime
- 1994-01-13 BR BR9403528A patent/BR9403528A/pt not_active Application Discontinuation
- 1994-01-13 CN CN94190012A patent/CN1036850C/zh not_active Expired - Lifetime
- 1994-01-13 EP EP94904315A patent/EP0644200B1/en not_active Expired - Lifetime
- 1994-01-13 DE DE69409895T patent/DE69409895T2/de not_active Expired - Lifetime
-
1996
- 1996-04-17 US US08/633,485 patent/US5681717A/en not_active Expired - Lifetime
- 1996-11-08 CN CN96114449A patent/CN1124339C/zh not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CN1036850C (zh) | 1997-12-31 |
KR0164235B1 (ko) | 1999-01-15 |
US5681717A (en) | 1997-10-28 |
ATE165606T1 (de) | 1998-05-15 |
CN1101208A (zh) | 1995-04-05 |
KR950700329A (ko) | 1995-01-16 |
EP0644200A1 (en) | 1995-03-22 |
JP3541385B2 (ja) | 2004-07-07 |
DE69409895D1 (de) | 1998-06-04 |
BR9403528A (pt) | 1999-05-25 |
EP0644200B1 (en) | 1998-04-29 |
WO1994015963A1 (en) | 1994-07-21 |
US5547864A (en) | 1996-08-20 |
DE69409895T2 (de) | 1998-12-24 |
CN1124339C (zh) | 2003-10-15 |
EP0644200A4 (en) | 1996-01-24 |
CN1160081A (zh) | 1997-09-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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