ES2115208T3 - Proteina de la superficie celular de brevibacterium lactofermentum. - Google Patents

Proteina de la superficie celular de brevibacterium lactofermentum.

Info

Publication number
ES2115208T3
ES2115208T3 ES94904315T ES94904315T ES2115208T3 ES 2115208 T3 ES2115208 T3 ES 2115208T3 ES 94904315 T ES94904315 T ES 94904315T ES 94904315 T ES94904315 T ES 94904315T ES 2115208 T3 ES2115208 T3 ES 2115208T3
Authority
ES
Spain
Prior art keywords
brevibacterium lactofermentum
protein
transformant
image
cellular surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94904315T
Other languages
English (en)
Inventor
Hisashi Kawasaki
Makoto Tsuchiya
Kiyoshi Miwa
Yoshio Kawahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Application granted granted Critical
Publication of ES2115208T3 publication Critical patent/ES2115208T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/345—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Brevibacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

SE PREPARA UN TRANSFORMADOR MEDIANTE LA INTRODUCCION EN UN CORINEFORME DE UN FRAGMENTO DE ADN QUE CONTIENE UN GEN CODIFICADO PARA UNA NUEVA PROTEINA DEL CORTEX CELULAR ORIGINADA EN BREVIBACTERIUM LACTOFERMENTUM Y QUE TIENE LAS DOS SECUENCIAS SIGUIENTES EN SU MOLECULA Y UN PESO MOLECULAR DE APROXIMADAMENTE 63,000 D: (1) THR-LEU-ARG-GLN-HIS-TYR-SER-SER-LEU_ILE-PRO-ASN-LEUPHE-ILE-ALA-ALA-VAL-GLY-ASN-ILE-ASN-GLU-LEU-ASN-ASN-ALA-ASP-GLN-ALAALA-ARG-GLU-LEU-PHE-LEU-ASP-TRP-ASP-THR, (2) ASN-LYS-THR-ASP-PHE-ALAGLU-ILE-GLU-LEU-TYR-ASP-VAL-LEU-TYR-THR-ASP-ALA-ASP-ILE-SER-GLY-ASPALA-PRO-LEU-LEU-ALA-PRO-ALA-TYR-LYS. ESTE TRANSFORMANTE O UNA ESTIRPE DEFICIENTE EN LA NUEVA PROTEINA DEL CORTEX DE CELULA, QUE HA SIDO RECIENTAMENTE PREPARADO, SE UTILIZA PARA PRODUCIR SUBSTANCIAS VALIOSAS QUE INCLUYEN L-AMINOACIDOS POR EL METODO DE FERMENTACION DE L-AMINOACIDO.
ES94904315T 1993-01-13 1994-01-13 Proteina de la superficie celular de brevibacterium lactofermentum. Expired - Lifetime ES2115208T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP406993 1993-01-13

Publications (1)

Publication Number Publication Date
ES2115208T3 true ES2115208T3 (es) 1998-06-16

Family

ID=11574537

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94904315T Expired - Lifetime ES2115208T3 (es) 1993-01-13 1994-01-13 Proteina de la superficie celular de brevibacterium lactofermentum.

Country Status (10)

Country Link
US (2) US5547864A (es)
EP (1) EP0644200B1 (es)
JP (1) JP3541385B2 (es)
KR (1) KR0164235B1 (es)
CN (2) CN1036850C (es)
AT (1) ATE165606T1 (es)
BR (1) BR9403528A (es)
DE (1) DE69409895T2 (es)
ES (1) ES2115208T3 (es)
WO (1) WO1994015963A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19903345A1 (de) * 1999-01-28 2000-08-03 Werner Lubitz Kompartimentierung von rekombinanten Polypeptiden in Wirtszellen
US6927046B1 (en) * 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
RU2264463C2 (ru) * 2001-03-30 2005-11-20 Адзиномото Ко., Инк. Способ секреторной продукции белка
CN100401896C (zh) * 2002-12-09 2008-07-16 儿童医院医疗中心 诊断和治疗间质性肺病的方法
US20040224340A1 (en) * 2003-04-21 2004-11-11 Filutowicz Marcin S. Displacing a plasmid in a bacterial population
WO2014126260A1 (ja) * 2013-02-18 2014-08-21 味の素株式会社 タンパク質の沈殿による製造方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50126877A (es) * 1974-03-28 1975-10-06
JPS5722558A (en) * 1980-07-16 1982-02-05 Mitsubishi Chem Ind Ltd Formwise measuring device for extreme trace of nitrogen
JPS57134500A (en) * 1981-02-12 1982-08-19 Kyowa Hakko Kogyo Co Ltd Plasmid pcg1
JPS57183799A (en) * 1981-04-17 1982-11-12 Kyowa Hakko Kogyo Co Ltd Novel plasmid
JPS5835197A (ja) * 1981-08-26 1983-03-01 Kyowa Hakko Kogyo Co Ltd プラスミドｐｃｇ２
JPS5867699A (ja) * 1981-10-16 1983-04-22 Ajinomoto Co Inc プラスミド
JPS5877895A (ja) * 1981-11-02 1983-05-11 Ajinomoto Co Inc プラスミドｐｈｍ１５１９
JPS58192900A (ja) * 1982-05-04 1983-11-10 Ajinomoto Co Inc 複合プラスミド
JPH0691829B2 (ja) * 1983-08-24 1994-11-16 味の素株式会社 発酵法によるｌ―リジンの製造法
JPH06102029B2 (ja) * 1984-07-31 1994-12-14 味の素株式会社 Ｌ−トリプトフアンの製造法
JPH07112431B2 (ja) * 1985-09-06 1995-12-06 味の素株式会社 遺伝子発現調節法
JPH06102024B2 (ja) * 1986-04-16 1994-12-14 味の素株式会社 新規プロモーター及び該プロモーターを用いた遺伝子発現方法
FR2627508B1 (fr) * 1988-02-22 1990-10-05 Eurolysine Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede
JPH02207791A (ja) * 1989-02-07 1990-08-17 Ajinomoto Co Inc 微生物の形質転換法
JPH07108228B2 (ja) * 1990-10-15 1995-11-22 味の素株式会社 温度感受性プラスミド
JPH04271780A (ja) * 1991-02-26 1992-09-28 Ajinomoto Co Inc リコンビナントリパーゼ
WO1993003158A1 (fr) * 1991-07-30 1993-02-18 Orsan Systeme d'expression et de secretion de proteines utilisables en particulier chez les corynebacteries

Also Published As

Publication number Publication date
CN1036850C (zh) 1997-12-31
KR0164235B1 (ko) 1999-01-15
US5681717A (en) 1997-10-28
ATE165606T1 (de) 1998-05-15
CN1101208A (zh) 1995-04-05
KR950700329A (ko) 1995-01-16
EP0644200A1 (en) 1995-03-22
JP3541385B2 (ja) 2004-07-07
DE69409895D1 (de) 1998-06-04
BR9403528A (pt) 1999-05-25
EP0644200B1 (en) 1998-04-29
WO1994015963A1 (en) 1994-07-21
US5547864A (en) 1996-08-20
DE69409895T2 (de) 1998-12-24
CN1124339C (zh) 2003-10-15
EP0644200A4 (en) 1996-01-24
CN1160081A (zh) 1997-09-24

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