ES2113906T3 - Composiciones polimericas utiles como implantes con administracion controlada. - Google Patents

Composiciones polimericas utiles como implantes con administracion controlada.

Info

Publication number
ES2113906T3
ES2113906T3 ES92116801T ES92116801T ES2113906T3 ES 2113906 T3 ES2113906 T3 ES 2113906T3 ES 92116801 T ES92116801 T ES 92116801T ES 92116801 T ES92116801 T ES 92116801T ES 2113906 T3 ES2113906 T3 ES 2113906T3
Authority
ES
Spain
Prior art keywords
liquid composition
implants
compositions useful
polymeric compositions
controlled administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92116801T
Other languages
English (en)
Inventor
Richard L Dunn
Arthur J Tipton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tolmar Therapeutics Inc
Original Assignee
Atrix Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Atrix Laboratories Inc filed Critical Atrix Laboratories Inc
Application granted granted Critical
Publication of ES2113906T3 publication Critical patent/ES2113906T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA INVENCION SE DIRIGE EN UN SISTEMA MEJORADO PARA LA LIBERACION CONTROLADA PARA MATERIALES BIOLOGICAMENTE ACTIVOS Y A UNA COMPOSICION LIQUIDA PARA SU FORMACION. LA COMPOSICION LIQUIDA SE COMPONE DE UN POLIMERO TERMOPLASTICO, UN AGENTE MODIFICADOR DE LA PROPORCION, UN MATERIAL BIOACTIVO Y UN SOLVENTE ORGANICO. LA COMPOSICION LIQUIDA ES CAPAZ DE FORMA UNA MATRIZ DE POLIMERO SOLIDA, MICROPOROSA, BIODEGRADABLE Y/O BIOEROSIONABLE. LA MATRIZ ES UTIL COMO IMPLANTE EN PACIENTES (HUMANOS Y ANIMALES) PARA LA LIBERACION DE SUBSTANCIAS BIOLOGICAMENTE ACTIVAS A TEJIDOS U ORGANOS.
ES92116801T 1991-10-15 1992-10-01 Composiciones polimericas utiles como implantes con administracion controlada. Expired - Lifetime ES2113906T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77681691A 1991-10-15 1991-10-15

Publications (1)

Publication Number Publication Date
ES2113906T3 true ES2113906T3 (es) 1998-05-16

Family

ID=25108453

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92116801T Expired - Lifetime ES2113906T3 (es) 1991-10-15 1992-10-01 Composiciones polimericas utiles como implantes con administracion controlada.

Country Status (9)

Country Link
US (1) US5945115A (es)
EP (1) EP0537559B1 (es)
JP (1) JPH05286850A (es)
KR (1) KR100260672B1 (es)
AT (1) ATE162398T1 (es)
AU (1) AU2605592A (es)
CA (1) CA2079830A1 (es)
DE (1) DE69224131T2 (es)
ES (1) ES2113906T3 (es)

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* Cited by examiner, † Cited by third party
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KR100260672B1 (ko) 2000-08-01
AU2605592A (en) 1993-04-22
US5945115A (en) 1999-08-31
EP0537559A1 (en) 1993-04-21
KR930007454A (ko) 1993-05-20
JPH05286850A (ja) 1993-11-02
DE69224131D1 (de) 1998-02-26
DE69224131T2 (de) 1998-04-30

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