ES2089245T3 - Agentes quelantes. - Google Patents

Agentes quelantes.

Info

Publication number
ES2089245T3
ES2089245T3 ES91919479T ES91919479T ES2089245T3 ES 2089245 T3 ES2089245 T3 ES 2089245T3 ES 91919479 T ES91919479 T ES 91919479T ES 91919479 T ES91919479 T ES 91919479T ES 2089245 T3 ES2089245 T3 ES 2089245T3
Authority
ES
Spain
Prior art keywords
pct
agents
cheling
date
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91919479T
Other languages
English (en)
Inventor
Joan F Carvalho
Shaun P Crofts
John Vadarajan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amersham Health Salutar Inc
Original Assignee
Nycomed Salutar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Salutar Inc filed Critical Nycomed Salutar Inc
Application granted granted Critical
Publication of ES2089245T3 publication Critical patent/ES2089245T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

LA INVENCION SE REFIERE A AGENTES QUELANTES MACROCICLICOS, QUE OPCIONALMENTE POSEEN MAS DE UN ANILLO MACROCICLICO PERO QUE SE CARACTERIZAN TIPICAMENTE POR SU POSESION DE AL MENOS DOS ENLACES PEPTIDOS DENTRO DEL ESQUELETO MACROCICLICO. ESTOS AGENTES QUELANTES PUEDEN USARSE POR EJEMPLO PARA LA PREPARACION DE QUELATOS DE METAL PARAMAGNETICO PARA SU USO COMO AGENTES DE CONTRASTE PARA TECNICAS DE MRI.
ES91919479T 1990-11-07 1991-11-06 Agentes quelantes. Expired - Lifetime ES2089245T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909024208A GB9024208D0 (en) 1990-11-07 1990-11-07 Compounds

Publications (1)

Publication Number Publication Date
ES2089245T3 true ES2089245T3 (es) 1996-10-01

Family

ID=10685010

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91919479T Expired - Lifetime ES2089245T3 (es) 1990-11-07 1991-11-06 Agentes quelantes.

Country Status (12)

Country Link
US (1) US5556968A (es)
EP (1) EP0556240B1 (es)
JP (1) JPH06504301A (es)
AT (1) ATE140219T1 (es)
AU (1) AU8862891A (es)
CA (1) CA2095727A1 (es)
DE (1) DE69120826T2 (es)
ES (1) ES2089245T3 (es)
GB (1) GB9024208D0 (es)
HK (1) HK1001560A1 (es)
IE (1) IE77162B1 (es)
WO (1) WO1992008707A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9024208D0 (en) 1990-11-07 1990-12-19 Salutar Inc Compounds
EP0524161A1 (en) * 1991-07-19 1993-01-20 Monsanto Company Manganese complexes of nitrogen containing macrocyclic ligands effective as catalysts for dismutating superoxide
US5739294A (en) * 1991-12-10 1998-04-14 The Dow Chemical Company Bicyclopol yazamacrocyclophosphonic acid complexes for use as contrast agents
WO1993025243A2 (en) * 1992-06-10 1993-12-23 Research Corporation Technologies, Inc. Metal complexes formed with macrocyclic ligands for use in imaging techniques
DE4344460A1 (de) * 1993-12-22 1995-06-29 Schering Ag Metallkomplexe von dendrimeren Makromolekülen, diese enthaltende diagnostische Mittel sowie Verfahren zur Herstellung der Komplexe und Mittel
DE4425857A1 (de) * 1994-07-07 1996-01-11 Schering Ag Kaskaden-Polymer-Komplexe, Verfahren zur ihrer Herstellung und diese enthaltende pharmazeutische Mittel
EP0830351A1 (en) * 1995-06-07 1998-03-25 Monsanto Company Process for preparing substituted polyazamacrocycles
US5801228A (en) * 1995-06-07 1998-09-01 Nycomed Imaging As Polymeric contrast agents for medical imaging
US6166200A (en) * 1995-07-04 2000-12-26 Schering Aktiengesellschaft Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes
DE19525924A1 (de) * 1995-07-04 1997-01-09 Schering Ag Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
JPH11511168A (ja) 1995-08-17 1999-09-28 モンサント カンパニー 窒素含有大環状リガンドの金属錯体の生体分子結合体を使用する診断造影検査方法
AU6722496A (en) * 1995-08-17 1997-03-12 Monsanto Company Methods of diagnostic image analysis using metal complexes of nitrogen-containing macrocyclic ligands
TW356468B (en) * 1995-09-15 1999-04-21 Astra Pharma Prod Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same
US6214817B1 (en) 1997-06-20 2001-04-10 Monsanto Company Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3723087A (en) * 1967-03-16 1973-03-27 Monsanto Co Herbicidal compositions and methods
JPS60165728A (ja) * 1984-02-08 1985-08-28 Toshiba Corp 薄膜形成方法
US5025023A (en) * 1985-08-30 1991-06-18 Bristol-Myers Company Peptide antibiotics
EP0250358A3 (en) * 1986-06-20 1988-10-05 Schering Aktiengesellschaft Novel complex compounds
DE3625417C2 (de) * 1986-07-28 1998-10-08 Schering Ag Tetraazacyclododecan-Derivate
US5132409A (en) * 1987-01-12 1992-07-21 Bracco Industria Chimica S.P.A. Macrocyclic chelating agents and chelates thereof
FR2614020B1 (fr) * 1987-04-14 1989-07-28 Guerbet Sa Nouveaux ligands cycliques azotes, complexes metalliques formes par ces ligands, compositions de diagnostic contenant ces complexes et procede de preparation des ligands.
DE3927444A1 (de) * 1989-08-16 1991-02-28 Schering Ag Verwendung von amid-komplexverbindungen
JPH02130592A (ja) * 1988-11-11 1990-05-18 Kawasaki Heavy Ind Ltd 輸送機関の客室の画像情報処理システム
US5194605A (en) * 1989-12-08 1993-03-16 Merck & Co., Inc. Cyclic renin inhibitors containing 2-substituted (3S,4S)-4-amino-5-cyclohexyl-3-hydroxy pentanoic acid, 2-substituted (3S,4S)-5-cyclohexyl-3,4-di-hydroxy pentanoic acid or 2-substituted (4S,5S)-5-amino-6-cyclohexyl-4-hydroxyhexanoic acid or its analogs
US4999349A (en) * 1990-03-22 1991-03-12 Bristol-Myers Squibb Co. BU-4164E - A and B, prolyl endopeptidase inhibitors
GB9024208D0 (en) * 1990-11-07 1990-12-19 Salutar Inc Compounds

Also Published As

Publication number Publication date
EP0556240B1 (en) 1996-07-10
AU8862891A (en) 1992-06-11
ATE140219T1 (de) 1996-07-15
GB9024208D0 (en) 1990-12-19
WO1992008707A1 (en) 1992-05-29
US5556968A (en) 1996-09-17
IE913873A1 (en) 1992-05-20
JPH06504301A (ja) 1994-05-19
HK1001560A1 (en) 1998-06-26
CA2095727A1 (en) 1992-05-08
DE69120826T2 (de) 1997-01-09
IE77162B1 (en) 1997-12-03
DE69120826D1 (de) 1996-08-14
EP0556240A1 (en) 1993-08-25

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