ES2071332T3 - Particulas coloidales de lipidos mixtos-bicarbonato para administrar farmacos o calorias. - Google Patents
Particulas coloidales de lipidos mixtos-bicarbonato para administrar farmacos o calorias.Info
- Publication number
- ES2071332T3 ES2071332T3 ES91917082T ES91917082T ES2071332T3 ES 2071332 T3 ES2071332 T3 ES 2071332T3 ES 91917082 T ES91917082 T ES 91917082T ES 91917082 T ES91917082 T ES 91917082T ES 2071332 T3 ES2071332 T3 ES 2071332T3
- Authority
- ES
- Spain
- Prior art keywords
- calories
- bicarbonate
- carbon atoms
- particles
- colloid particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE MUESTRA UNA COMPOSICION QUE CONTIENE ACIDOS GRASOS NO ESTERIFICADOS QUE TIENEN DE 14 A 18 ATOMOS DE CARBONO, MONOGLICERIDOS QUE SON MONOESTERES DE GLICEROL Y ACIDOS GRASOS QUE TIENEN DE 14 A 18 ATOMOS DE CARBONO, LISOFOSFOTIDILCOLINA EN LA CUAL LA MITAD DEL ACIDO GRASO TIENE DE 14 A 18 ATOMOS DE CARBONO Y BICARBONATO. LAS COMPOSICIONES PUEDEN TENER OPCIONALMENTE SALES. ESTAS COMPOSICIONES FORMAN PARTICULAS COLOIDALES DE TALLA SUBMICRON Y PUEDEN ACTUAR COMO VEHICULOS PARA TRANSPORTAR FARMACOS ADMINISTRADOS ORALMENTE, FUENTES DE CALORIAS EN FORMA DE GRASAS FACILMENTE ABSORBIBLES Y COMO PARTICULAS PARA LA APLICACION TOPICA EN LA PIEL. TAMBIEN SE DESCRIBE UN METODO PARA FABRICAR ESTAS PARTICULAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56724390A | 1990-08-13 | 1990-08-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2071332T3 true ES2071332T3 (es) | 1995-06-16 |
Family
ID=24266341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91917082T Expired - Lifetime ES2071332T3 (es) | 1990-08-13 | 1991-08-12 | Particulas coloidales de lipidos mixtos-bicarbonato para administrar farmacos o calorias. |
Country Status (9)
Country | Link |
---|---|
US (3) | US5314921A (es) |
EP (1) | EP0543943B1 (es) |
JP (1) | JP3273785B2 (es) |
AT (1) | ATE121618T1 (es) |
AU (1) | AU666293B2 (es) |
CA (1) | CA2089003C (es) |
DE (1) | DE69109297T2 (es) |
ES (1) | ES2071332T3 (es) |
WO (1) | WO1992003121A1 (es) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5891466A (en) * | 1990-08-13 | 1999-04-06 | Yesair; David W. | Mixed Liped-Bicarbonate colloidal particles for delivering drugs or calories |
CA2089003C (en) * | 1990-08-13 | 2001-03-20 | David W. Yesair | Mixed lipid-bicarbonate colloidal particles for delivering drugs or calories |
GB9212511D0 (en) * | 1992-06-12 | 1992-07-22 | Cortecs Ltd | Pharmaceutical compositions |
US5514670A (en) * | 1993-08-13 | 1996-05-07 | Pharmos Corporation | Submicron emulsions for delivery of peptides |
US5744155A (en) * | 1993-08-13 | 1998-04-28 | Friedman; Doron | Bioadhesive emulsion preparations for enhanced drug delivery |
EP0750604B1 (en) * | 1994-03-14 | 1997-12-29 | Morten Sloth Weidner | A method of rendering organic compounds soluble in fatty systems, novel chemical complexes of such compounds and various applications of the complexes |
JPH11506780A (ja) * | 1995-06-06 | 1999-06-15 | バイオモレキュラー プロダクツ,インク. | 薬またはカロリー送達用の混合脂質−重炭酸塩コロイド粒子 |
PT969813E (pt) * | 1997-02-24 | 2004-12-31 | Sla Pharma Ag | Composicao farmaceutica topica compreendendo um agente colinergico ou um bloqueador de canal de calcio |
US6086915A (en) * | 1998-04-01 | 2000-07-11 | Bioresponse L.L.C. | Compositions and methods of adjusting steroid hormone metabolism through phytochemicals |
US6524620B2 (en) | 1998-07-20 | 2003-02-25 | Andrx Pharmaceuticals, Inc. | Diltiazem controlled release formulation and method of manufacture |
DE69934325T2 (de) * | 1998-09-08 | 2007-07-05 | Biomolecular Products, Inc., Byfield | Zusammenstellungen zur erhöhung der darmabsoption von fetten |
US6172122B1 (en) | 1998-12-17 | 2001-01-09 | The Lubrizol Corporation | Stable emulsions from gelled overbased substrates with surfactants and aqueous liquids |
US6267985B1 (en) | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
US6761903B2 (en) | 1999-06-30 | 2004-07-13 | Lipocine, Inc. | Clear oil-containing pharmaceutical compositions containing a therapeutic agent |
US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US6383471B1 (en) | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
US6309663B1 (en) | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
US6458383B2 (en) | 1999-08-17 | 2002-10-01 | Lipocine, Inc. | Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin |
US20030236236A1 (en) * | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
US7732404B2 (en) * | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
US6861060B1 (en) | 2000-04-21 | 2005-03-01 | Elena Luriya | Personal care formulations |
WO2002058689A1 (en) * | 2000-12-05 | 2002-08-01 | Childrens Hospital Los Angeles | Pharmaceutical compositions of fenretinide having increased bioavailability and methods of using the same |
IL161178A0 (en) * | 2001-10-11 | 2004-08-31 | Biomolecular Products Inc | MODIFICATIONS OF SOLID 3-sn-PHOSPHOGLYCERIDES |
WO2004064805A1 (en) * | 2003-01-15 | 2004-08-05 | Biodelivery Sciences International, Inc. | Cochleate preparations of fragile nutrients |
WO2004069203A2 (en) * | 2003-01-31 | 2004-08-19 | Childrens Hospital Los Angeles Research Institute | Oral compositions of fenretinide having increased bioavailability and methods of using the same |
PT1516622E (pt) * | 2003-09-18 | 2008-02-04 | Tecnimede Sociedade Tecnico Medicinal Sa | Composição farmacêutica estável de cloridrato de diltiazem para aplicação cutânea e processo para a sua preparação |
US20060003002A1 (en) * | 2003-11-03 | 2006-01-05 | Lipocine, Inc. | Pharmaceutical compositions with synchronized solubilizer release |
NZ572601A (en) | 2006-03-29 | 2012-03-30 | Univ Wayne State | Liposomal nanoparticles and other formulations of fenretinide for use in therapy and drug delivery |
EP2200613B1 (en) | 2007-09-21 | 2018-09-05 | The Johns Hopkins University | Phenazine derivatives and uses thereof |
CA2718416C (en) * | 2008-03-13 | 2018-01-02 | Mallinckrodt Inc. | Multi-function, foot-activated controller for imaging system |
US11304960B2 (en) | 2009-01-08 | 2022-04-19 | Chandrashekar Giliyar | Steroidal compositions |
US20180153904A1 (en) | 2010-11-30 | 2018-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
US20170246187A1 (en) | 2014-08-28 | 2017-08-31 | Lipocine Inc. | (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE |
WO2016033556A1 (en) | 2014-08-28 | 2016-03-03 | Lipocine Inc. | BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS |
WO2018098501A1 (en) | 2016-11-28 | 2018-05-31 | Lipocine Inc. | Oral testosterone undecanoate therapy |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA725596A (en) * | 1960-08-26 | 1966-01-11 | J. Wretlind Arvid | Method of preparing intravenously injectable fat emulsions free from side reactions or complications |
JPS5321393B2 (es) * | 1974-10-19 | 1978-07-03 | ||
JPS53107408A (en) * | 1977-02-28 | 1978-09-19 | Yamanouchi Pharmaceut Co Ltd | Micellar preparation for rectal infusion |
FR2427100A1 (fr) * | 1978-06-02 | 1979-12-28 | Kali Chemie Pharma Gmbh | Composition pharmaceutique a propriete de resorption amelioree et procede pour sa fabrication |
JPS6030652B2 (ja) * | 1979-05-07 | 1985-07-17 | 株式会社ミドリ十字 | 静脈注射用脂肪乳剤 |
JPS5618914A (en) * | 1979-07-25 | 1981-02-23 | Eisai Co Ltd | Ubidecarenone composition having good absorbability |
FR2497668B1 (fr) * | 1981-01-15 | 1986-03-21 | Gattefosse Ets Sa | Emulsions lipoproteiques injectables, leur procede de preparation et leurs applications en therapeutique |
JPS57167926A (en) * | 1981-04-08 | 1982-10-16 | Mitsubishi Chem Ind Ltd | External base for skin |
EP0084052A1 (en) * | 1981-07-23 | 1983-07-27 | Arthur D. Little, Inc. | Micellular drug delivery system |
US4454113A (en) * | 1982-09-21 | 1984-06-12 | Scm Corporation | Stabilization of oil and water emulsions using polyglycerol esters of fatty acids |
US4874795A (en) * | 1985-04-02 | 1989-10-17 | Yesair David W | Composition for delivery of orally administered drugs and other substances |
IE59067B1 (en) * | 1985-04-02 | 1993-12-15 | Yesair David W | Composition for delivery of orally administered drugs and other substances |
US4849132A (en) * | 1986-05-16 | 1989-07-18 | Asahi Denka Kogyo Kabushiki Kaisha | Surfactant composition having improved functions |
CA2089003C (en) * | 1990-08-13 | 2001-03-20 | David W. Yesair | Mixed lipid-bicarbonate colloidal particles for delivering drugs or calories |
-
1991
- 1991-08-12 CA CA002089003A patent/CA2089003C/en not_active Expired - Lifetime
- 1991-08-12 EP EP19910917082 patent/EP0543943B1/en not_active Expired - Lifetime
- 1991-08-12 ES ES91917082T patent/ES2071332T3/es not_active Expired - Lifetime
- 1991-08-12 AU AU86462/91A patent/AU666293B2/en not_active Ceased
- 1991-08-12 DE DE69109297T patent/DE69109297T2/de not_active Expired - Fee Related
- 1991-08-12 JP JP51750491A patent/JP3273785B2/ja not_active Expired - Lifetime
- 1991-08-12 AT AT91917082T patent/ATE121618T1/de not_active IP Right Cessation
- 1991-08-12 WO PCT/US1991/005716 patent/WO1992003121A1/en active IP Right Grant
-
1992
- 1992-06-30 US US07/908,442 patent/US5314921A/en not_active Expired - Lifetime
-
1994
- 1994-05-05 US US08/238,592 patent/US5741822A/en not_active Expired - Lifetime
-
1995
- 1995-05-24 US US08/449,225 patent/US5707873A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2089003C (en) | 2001-03-20 |
US5314921A (en) | 1994-05-24 |
EP0543943A1 (en) | 1993-06-02 |
EP0543943B1 (en) | 1995-04-26 |
CA2089003A1 (en) | 1992-02-14 |
WO1992003121A1 (en) | 1992-03-05 |
AU666293B2 (en) | 1996-02-08 |
US5707873A (en) | 1998-01-13 |
ATE121618T1 (de) | 1995-05-15 |
DE69109297D1 (de) | 1995-06-01 |
DE69109297T2 (de) | 1995-11-09 |
JPH06503815A (ja) | 1994-04-28 |
AU8646291A (en) | 1992-03-17 |
US5741822A (en) | 1998-04-21 |
JP3273785B2 (ja) | 2002-04-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2071332T3 (es) | Particulas coloidales de lipidos mixtos-bicarbonato para administrar farmacos o calorias. | |
ID26221A (id) | Komposisi-komposisi farmasi yang dapat dijadikan gel | |
WO1993006812A3 (de) | Verwendung einer emulsion, zur herstellung eines arzneimittels zur i.v.-verabreichung zur behandlung von hauterkrankungen | |
JPS5777626A (en) | Palatable composition containing oil or oily substance | |
KR970704433A (ko) | 의약 조성물로서의 DHA의 용도(Use of DHA as a pharmaceutical composition) | |
AU531878B2 (en) | Medicated animal feed based on liver meal | |
KR940005267A (ko) | 경피투여용 기제 | |
SI9520139B (sl) | Halkoni in njihovi estri z antiproliferativno učinkovitostjo na tumorje maternice, jajčnikov in dojk | |
GB2004741A (en) | Cosmetic and pharmaceutical compositions for the skin | |
PT84657B (pt) | Processo para a fluidificacao, mediante glicofurol, de composicoes farmaceuticas contendo fosfatidil-colina, destinadas a serem introduzidas em capsulas moles de gelatina | |
AU554413B2 (en) | Linoleic acid and essential fatty acid compositions as | |
AU563273B2 (en) | Composition containing an essential fatty acid and niacin and/or a bile salt binder | |
JPH09309813A (ja) | 皮膚外用剤 | |
DE69614855D1 (de) | Gemischte lipid-bicarbonat kolloidale partikel zur abgabe von arzneistoffen oder kalorien | |
ES8400028A1 (es) | Metodo de preparacion de una composicion tixotropica anhidra. | |
SE8800989D0 (sv) | Dietary composition and process for preparing same | |
KR890701098A (ko) | 히드로퀴논 및 코지산을 함유하는 제약 또는 화장제 조성물 | |
SE8800990D0 (sv) | Skin-regenerating cosmetic compositon and process for preparing same | |
EP0876159A1 (en) | Composition for treating skin affections and process for its preparation | |
SE8104657L (sv) | Injicerbara farmaceutiska kompositioner | |
AU7338587A (en) | Pharmaceutical compositions of furosemide, piretanide or lemidosul in a fatty acid alkanolamide base | |
YU48388B (sh) | Postupak za dobijanje farmaceutske masti koja ne iritira kožu | |
IT1226144B (it) | Di estere fosforico dell'acido ursodeossicolico e suoi derivati, processo per la loro preparazione e composizioni terapeutiche che li contengono come principi attivi. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 543943 Country of ref document: ES |