ES2066096T3 - 4-bencil-5-fenil-2,4-dihidro-3h-1,2,4-triazol-3-onas y su uso como anticonvulsivos. - Google Patents

4-bencil-5-fenil-2,4-dihidro-3h-1,2,4-triazol-3-onas y su uso como anticonvulsivos.

Info

Publication number
ES2066096T3
ES2066096T3 ES90124971T ES90124971T ES2066096T3 ES 2066096 T3 ES2066096 T3 ES 2066096T3 ES 90124971 T ES90124971 T ES 90124971T ES 90124971 T ES90124971 T ES 90124971T ES 2066096 T3 ES2066096 T3 ES 2066096T3
Authority
ES
Spain
Prior art keywords
triazol
anticonvulsives
bencil
dihidro
fenil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90124971T
Other languages
English (en)
Inventor
John M Kane
Francis P Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2066096T3 publication Critical patent/ES2066096T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms

Abstract

ESTA INVENCION SE REFIERE A 4-BENCILO-5-FENILO-1, 2, 4-DIHIDRO-3H-1, 2, 4 TRIAZOL-3-ONAS Y SU UTILIZACION COMO ANTICONVULSIVOS PARA EL TRATAMIENTO DE ATAQUES.
ES90124971T 1989-12-20 1990-12-20 4-bencil-5-fenil-2,4-dihidro-3h-1,2,4-triazol-3-onas y su uso como anticonvulsivos. Expired - Lifetime ES2066096T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/453,440 US4966909A (en) 1989-12-20 1989-12-20 4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants

Publications (1)

Publication Number Publication Date
ES2066096T3 true ES2066096T3 (es) 1995-03-01

Family

ID=23800598

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90124971T Expired - Lifetime ES2066096T3 (es) 1989-12-20 1990-12-20 4-bencil-5-fenil-2,4-dihidro-3h-1,2,4-triazol-3-onas y su uso como anticonvulsivos.

Country Status (12)

Country Link
US (1) US4966909A (es)
EP (1) EP0435177B1 (es)
JP (1) JP2968053B2 (es)
KR (1) KR0154529B1 (es)
AT (1) ATE113591T1 (es)
AU (1) AU634003B2 (es)
DE (1) DE69013871T2 (es)
DK (1) DK0435177T3 (es)
ES (1) ES2066096T3 (es)
IE (1) IE64989B1 (es)
PH (1) PH27352A (es)
ZA (1) ZA9010080B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4966909A (en) * 1989-12-20 1990-10-30 Merrell Dow Pharmaceuticals 4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants
SE470120B (sv) * 1992-04-03 1993-11-08 Whirlpool Int Förfarande för styrning av mikrovågsenergin i en mikrovågsugn och mikrovågsugn för genomförande av förfarandet
ATE194334T1 (de) * 1995-04-20 2000-07-15 Aventis Pharma Inc 3-phenyl-1,4-dialkyl-1,2,4-triazolium salze und ihre verwendung als antidepressiva
TW467902B (en) * 1996-07-31 2001-12-11 Bristol Myers Squibb Co Diphenyl heterocycles as potassium channel modulators
US6489487B1 (en) * 1998-08-03 2002-12-03 Sumitomo Chemical Company, Limited Triazolone derivatives, use thereof, and intermediates therefor
US6156775A (en) * 1999-03-01 2000-12-05 Novartis Ag Use of fluorinated triazoles in treating affective and attention disorders
TW200505441A (en) 2003-03-24 2005-02-16 Hoffmann La Roche Non-nucleoside reverse transcriptase inhibitorsⅠ
US7400548B2 (en) * 2005-02-09 2008-07-15 International Business Machines Corporation Method for providing multiple reads/writes using a 2read/2write register file array
JP2010522706A (ja) 2007-03-29 2010-07-08 エフ．ホフマン−ラ ロシュ アーゲー 非ヌクレオシド逆転写酵素阻害剤
JP2022189000A (ja) 2021-06-10 2022-12-22 Ｔｍｔマシナリー株式会社 紡糸引取装置

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1126882B (de) * 1960-05-03 1962-04-05 Boehringer Sohn Ingelheim Verfahren zur Herstellung von 1,2,4-Triazolonen-(5)
BE621842A (es) * 1962-08-27
GB1068083A (en) * 1964-04-02 1967-05-10 Philippe Gold Aubert í¸-1,2,4-triazolone-(5) derivatives
US3621099A (en) * 1969-03-05 1971-11-16 Charles R Jacobson Therapeutic compositions and methods for stimulating the central nervous system
EP0036711B1 (en) * 1980-03-22 1985-12-04 Fbc Limited Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use
DD153953A3 (de) * 1980-04-01 1982-02-17 Gottfried Schuster Mittel zur chemotherapie von virosen der kulturpflanzen
DD160447A1 (de) * 1981-03-26 1983-08-03 Johannes Dost Herbizide mittel, die 1,2,4-triazolinone-(5) enthalten
BE894856A (fr) * 1982-10-28 1983-02-14 Fahlberg List Veb Compositions herbicides a base d'un derive de la 1,2,4-triazolinone-(5)
JP2593084B2 (ja) * 1986-12-19 1997-03-19 メレルダウファーマスーティカルズ インコーポレーテッド ５−アリールー３ｈ−１，２，４−トリアゾールー３−オン類の神経変性障害の処置への用途
PH24094A (en) * 1986-12-19 1990-03-05 Merrell Dow Pharma 5-aryl-3h-1,2,4-triazol-3-ones and their use as anticonvulsants
US4966909A (en) * 1989-12-20 1990-10-30 Merrell Dow Pharmaceuticals 4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants

Also Published As

Publication number Publication date
KR0154529B1 (ko) 1998-11-16
EP0435177A2 (en) 1991-07-03
US4966909A (en) 1990-10-30
DK0435177T3 (da) 1994-11-21
AU634003B2 (en) 1993-02-11
DE69013871T2 (de) 1995-03-09
IE904599A1 (en) 1991-07-03
IE64989B1 (en) 1995-09-20
JPH04128271A (ja) 1992-04-28
KR910011807A (ko) 1991-08-07
ATE113591T1 (de) 1994-11-15
DE69013871D1 (de) 1994-12-08
AU6808190A (en) 1991-06-27
PH27352A (en) 1993-06-21
JP2968053B2 (ja) 1999-10-25
EP0435177A3 (en) 1992-01-08
ZA9010080B (en) 1991-10-30
EP0435177B1 (en) 1994-11-02

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