ES2062527T3 - Preparacion oral que puede ser liberada en una region apropiada del intestino. - Google Patents

Preparacion oral que puede ser liberada en una region apropiada del intestino.

Info

Publication number
ES2062527T3
ES2062527T3 ES90907437T ES90907437T ES2062527T3 ES 2062527 T3 ES2062527 T3 ES 2062527T3 ES 90907437 T ES90907437 T ES 90907437T ES 90907437 T ES90907437 T ES 90907437T ES 2062527 T3 ES2062527 T3 ES 2062527T3
Authority
ES
Spain
Prior art keywords
component
intestine
region
core
oral preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90907437T
Other languages
English (en)
Inventor
Heiji Ikushima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2062527T3 publication Critical patent/ES2062527T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UNA PREPARACION ORAL COMPUESTA DE UN NUCLEO INCLUYENDO UN AGENTE PRINCIPAL Y UN ENVASADO FARMACEUTICAMENTE ACEPTABLE; LA PRIMERA CAPA QUE CUBRE EL NUCLEO, QUE INCLUYE UN COMPONENTE EUTERICO O SOLUBLE EN AGUA Y PUEDE CONTENER OPCIONALMENTE UN COMPONENTE INSOLUBLE; LA SEGUNDA CAPA QUE CUBRE LA PRIMERA CAPA, INCLUYE UN COMPONENTE NO-EUTERICO EL CUAL SE DISUELVE MEDIANTE LA REACCION CON AL MENOS UNO DE LOS COMPONENTES DEL NUCLEO; Y LA TERCERA CAPA QUE CUBRE LA SEGUNDA, INCLUYE UN COMPONENTE EUTERICO. ESTA PREPARACION NO PUEDE SOLTAR EL AGENTE PRINCIPAL HASTA QUE ALCANZA LA REGION DESEADA DEL INTESTINO Y PUEDE SALTAR EL AGENTE EN UN PROMEDIO CONTROLABLE UNA VEZ ALCANZA LA REGION. DE ESTE MODO PUEDE SER USADO DE FORMA EFECTIVA EN LA ADMINISTRACION DE UN AGENTE PRINCIPAL TENIENDO UNA ABSORCION ESPECIFICA EN UNA REGION PARTICULAR DEL INTESTINO O TRATANDO UNA ENFERMEDAD EN UNA REGION PARTICULAR DEL INTESTINO.
ES90907437T 1989-05-11 1990-05-10 Preparacion oral que puede ser liberada en una region apropiada del intestino. Expired - Lifetime ES2062527T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11608689 1989-05-11

Publications (1)

Publication Number Publication Date
ES2062527T3 true ES2062527T3 (es) 1994-12-16

Family

ID=14678366

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90907437T Expired - Lifetime ES2062527T3 (es) 1989-05-11 1990-05-10 Preparacion oral que puede ser liberada en una region apropiada del intestino.

Country Status (8)

Country Link
EP (1) EP0425699B1 (es)
JP (1) JP2967492B2 (es)
AT (1) ATE109973T1 (es)
CA (1) CA2032475C (es)
DE (1) DE69011618T2 (es)
DK (1) DK0425699T3 (es)
ES (1) ES2062527T3 (es)
WO (1) WO1990013286A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578316A (en) * 1992-06-04 1996-11-26 Smithkline Beecham Corporation Palatable pharmaceutical compositions
ES2149250T3 (es) * 1993-04-23 2000-11-01 Novartis Ag Dispositivo para la administracion de medicamentos con liberacion controlada.
US5447729A (en) * 1994-04-07 1995-09-05 Pharmavene, Inc. Multilamellar drug delivery systems
GB9412394D0 (en) 1994-06-21 1994-08-10 Danbiosyst Uk Colonic drug delivery composition
SG80553A1 (en) * 1995-07-20 2001-05-22 Tanabe Seiyaku Co Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
JP3185206B2 (ja) * 1995-07-20 2001-07-09 田辺製薬株式会社 消化管下部放出型被覆カプセル製剤
JPH10152431A (ja) * 1996-08-02 1998-06-09 Hisamitsu Pharmaceut Co Inc 経口製剤用カプセルと経口カプセル製剤
CN1158071C (zh) * 1997-05-30 2004-07-21 渗透有限公司 多层渗透装置
KR100501022B1 (ko) 1998-07-28 2005-07-18 다나베 세이야꾸 가부시키가이샤 장내 적소 방출형 제제
JP2003201256A (ja) * 2001-12-28 2003-07-18 Hisamitsu Pharmaceut Co Inc 大腸送達性経口医薬製剤、大腸癌治療用経口医薬製剤および大腸炎治療用経口医薬製剤
JP4694145B2 (ja) * 2004-05-17 2011-06-08 株式会社 メドレックス 経口腸溶性製剤
US20060280795A1 (en) * 2005-06-08 2006-12-14 Dexcel Pharma Technologies, Ltd. Specific time-delayed burst profile delivery system
AU2008230364A1 (en) 2007-03-26 2008-10-02 Teikoku Seiyaku Co., Ltd. Oral pharmaceutical preparation for colon-specific delivery
WO2013035081A2 (de) * 2011-09-07 2013-03-14 JÄNISCH, Melisa Optimale formulierung zur freisetzung eines wirkstoffes im dickdarm
PL3398587T3 (pl) * 2015-12-28 2024-01-22 Ssp Co., Ltd., Japan Skompaktowany preparat farmaceutyczny

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2471186A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation
GB8518301D0 (en) * 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
DE3812799A1 (de) * 1988-04-16 1989-10-26 Sanol Arznei Schwarz Gmbh Oral zu verabreichende pharmazeutische zubereitung mit kontrollierter wirkstofffreisetzung und verfahren zu deren herstellung
IT1230576B (it) * 1988-10-20 1991-10-28 Angeli Inst Spa Formulazioni farmaceutiche per via orale a liberazione selettiva nel colon

Also Published As

Publication number Publication date
EP0425699A4 (en) 1991-11-13
DE69011618T2 (de) 1994-12-15
EP0425699A1 (en) 1991-05-08
JPH0372417A (ja) 1991-03-27
WO1990013286A1 (fr) 1990-11-15
CA2032475C (en) 1997-12-30
DE69011618D1 (de) 1994-09-22
DK0425699T3 (da) 1994-11-21
ATE109973T1 (de) 1994-09-15
JP2967492B2 (ja) 1999-10-25
CA2032475A1 (en) 1990-11-12
EP0425699B1 (en) 1994-08-17

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