ES2061624T3 - Compuestos fenilicos sustituidos con amino-etilo en posicion beta, y composiciones anti-inflamatorias o analgesicas que los contienen. - Google Patents

Compuestos fenilicos sustituidos con amino-etilo en posicion beta, y composiciones anti-inflamatorias o analgesicas que los contienen.

Info

Publication number
ES2061624T3
ES2061624T3 ES88200382T ES88200382T ES2061624T3 ES 2061624 T3 ES2061624 T3 ES 2061624T3 ES 88200382 T ES88200382 T ES 88200382T ES 88200382 T ES88200382 T ES 88200382T ES 2061624 T3 ES2061624 T3 ES 2061624T3
Authority
ES
Spain
Prior art keywords
fenilic
inflammatory
ethyl
amino
contain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88200382T
Other languages
English (en)
Inventor
Joseph H Garnder
Gerald B Kasting
Thomas L Cupps
Richard S Echler
Thomas W Gibson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Application granted granted Critical
Publication of ES2061624T3 publication Critical patent/ES2061624T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • C07C335/10—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C335/12—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A COMPUESTOS DEL TITULO EN ESPECIAL A LOS BETA-AMINOETOXISUSTITUIDOS DE ESTRUCTURA (I) DONDE R, Z, W-X, R1 Y R2 TIENEN EL SIGNIFICADO QUE SE DETALLA EN LA INVENCION
ES88200382T 1987-03-09 1988-03-01 Compuestos fenilicos sustituidos con amino-etilo en posicion beta, y composiciones anti-inflamatorias o analgesicas que los contienen. Expired - Lifetime ES2061624T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2359887A 1987-03-09 1987-03-09
US14961888A 1988-02-12 1988-02-12

Publications (1)

Publication Number Publication Date
ES2061624T3 true ES2061624T3 (es) 1994-12-16

Family

ID=26697376

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88200382T Expired - Lifetime ES2061624T3 (es) 1987-03-09 1988-03-01 Compuestos fenilicos sustituidos con amino-etilo en posicion beta, y composiciones anti-inflamatorias o analgesicas que los contienen.

Country Status (13)

Country Link
EP (1) EP0282127B1 (es)
JP (1) JP2562475B2 (es)
KR (1) KR960012204B1 (es)
AU (1) AU621041B2 (es)
CA (1) CA1328457C (es)
DE (1) DE3887544T2 (es)
DK (1) DK127588A (es)
ES (1) ES2061624T3 (es)
FI (1) FI98812C (es)
HK (1) HK94596A (es)
IE (1) IE60992B1 (es)
NO (1) NO180117C (es)
NZ (1) NZ223790A (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5045565A (en) * 1987-03-09 1991-09-03 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5099030A (en) * 1987-03-09 1992-03-24 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5461075A (en) * 1988-06-17 1995-10-24 The Procter & Gamble Company Use of vanilloids for the prevention of lesions due to herpes simplex infections
DE68918991T2 (de) * 1988-06-17 1995-04-27 Procter & Gamble Anwendung von Vanillin-Derivaten zur Herstellung eines Arzneimittels zur Behandlung von Herpes simplex-Infektion.
US5403868A (en) * 1988-12-23 1995-04-04 Sandoz Ltd. Capsaicin derivatives
HU206082B (en) * 1988-12-23 1992-08-28 Sandoz Ag Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds
CA2017383A1 (en) * 1989-06-08 1990-12-08 Raymond R. Martodam Use of vanilloids for the treatment of respiratory diseases or disorders
HU210683B (en) * 1990-06-18 1995-06-28 Sandoz Ag Process for producing n-benzyl-n1-(phenyl-alkyl)-thiourea derivatives and pharmaceutical compositions containing the same
US5242944A (en) * 1991-06-20 1993-09-07 Korea Research Institute Of Chemical Technology Phenylacetamide derivatives and pharmaceutical compositions thereof
DE69224861T2 (de) * 1991-07-30 1998-08-06 Korea Res Inst Chem Tech Neue Phenylacetamidderivate und Verfahren zu ihrer Herstellung
KR0147963B1 (ko) * 1995-01-10 1998-08-17 강박광 엔-아릴알킬페닐아세트아미드 유도체와 그의 제조방법
GB9519270D0 (en) * 1995-09-21 1995-11-22 Sandoz Pharma Uk Organic compounds
GB2321455A (en) * 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
WO2002067966A1 (en) 2001-02-22 2002-09-06 Purdue Research Foundation Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer
US7192612B2 (en) 2001-02-22 2007-03-20 Purdue Research Foundation Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer
TWI239942B (en) 2001-06-11 2005-09-21 Dainippon Pharmaceutical Co N-arylphenylacetamide derivative and pharmaceutical composition containing the same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1894375A (en) * 1933-01-17 Basic product and process of making it
US4177280A (en) * 1978-07-03 1979-12-04 Syntex (U.S.A.) Inc. Bicyclo[3.1.0]hexyl-substituted carbonylaminophenoxy cardiovascular agents
JPS56118048A (en) * 1980-02-22 1981-09-16 Tanabe Seiyaku Co Ltd Phenoxyalkane derivative and its preparation
US4620279A (en) * 1983-07-29 1986-10-28 Standard Oil Company, Now Amoco Corporation Data transfer system
US4599342A (en) * 1984-01-16 1986-07-08 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
EP0187009B1 (en) * 1984-12-20 1988-07-06 The Procter & Gamble Company Compounds and compositions having anti-inflammatory and analgesic activity
GB2178031B (en) * 1985-06-10 1989-07-26 Procter & Gamble Phenylacetic acid amides having anti-inflammatory and analgesic activity

Also Published As

Publication number Publication date
EP0282127B1 (en) 1994-02-02
IE60992B1 (en) 1994-09-07
JP2562475B2 (ja) 1996-12-11
DK127588A (da) 1988-09-10
CA1328457C (en) 1994-04-12
DE3887544T2 (de) 1994-06-01
FI881064A0 (fi) 1988-03-08
AU621041B2 (en) 1992-03-05
DE3887544D1 (de) 1994-03-17
NO180117B (no) 1996-11-11
HK94596A (en) 1996-06-07
FI98812C (fi) 1997-08-25
KR880011082A (ko) 1988-10-26
NZ223790A (en) 1991-03-26
NO881020D0 (no) 1988-03-08
KR960012204B1 (ko) 1996-09-16
FI881064A (fi) 1988-09-10
NO180117C (no) 1997-02-19
FI98812B (fi) 1997-05-15
NO881020L (no) 1988-12-13
JPS63295537A (ja) 1988-12-01
DK127588D0 (da) 1988-03-09
AU1279588A (en) 1988-10-27
EP0282127A2 (en) 1988-09-14
IE880663L (en) 1988-09-09
EP0282127A3 (en) 1990-08-01

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