ES2058167T3 - 9-hidroxiamino-tetrahidro-acridinas, un procedimiento para su preparacion y su uso como medicamentos. - Google Patents
9-hidroxiamino-tetrahidro-acridinas, un procedimiento para su preparacion y su uso como medicamentos.Info
- Publication number
- ES2058167T3 ES2058167T3 ES88106108T ES88106108T ES2058167T3 ES 2058167 T3 ES2058167 T3 ES 2058167T3 ES 88106108 T ES88106108 T ES 88106108T ES 88106108 T ES88106108 T ES 88106108T ES 2058167 T3 ES2058167 T3 ES 2058167T3
- Authority
- ES
- Spain
- Prior art keywords
- loweralkyl
- hydrogen
- acridines
- hydroxyamino
- tetrahydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
SE DESCRIBEN NUEVOS COMPUESTOS DE FORMULA (I)M EN DONDE N TIENE UN VALOR DE 1 A 4; X ES HIDROGENO, ALQUILO O ALCOXI DE CADENA CORTA, CICLOALQUILO, HALOGENO, HIDROXI, NITRO, TRIFLUORMETILO, FORMILO, ALQUILCARBONILO, ARILCARBONILO, -SH. ALQUILTIO, -NHCOR2 O -NR3R4 (SIENDO R2 HIDROGENO O ALQUILO DE CADENA CORTA Y R3 Y R4 SON INDEPENDIENTEMENTE HIDROGENO, ALQUILO DE CADENA CORTA, ARILO, DIALQUILAMINOALQUILO, ARILALQUILO, FURILALQUILO, TIENILALQUILO, PIRIDINILALQUILO, DIARILALQUILO, ARILALQUILO O DIARILALQUILO CON PUENTES DE HIDROGENO. TAMBIEN SE REFIERE LA INVENCION A SUS ISOMEROS ESTEREO, OPTICOS O GEOMETRICOS Y A SUS SALES DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLES, QUE SON UTILES PARA REFORZAR LA MEMORIA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3988387A | 1987-04-20 | 1987-04-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2058167T3 true ES2058167T3 (es) | 1994-11-01 |
Family
ID=21907847
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88106108T Expired - Lifetime ES2058167T3 (es) | 1987-04-20 | 1988-04-16 | 9-hidroxiamino-tetrahidro-acridinas, un procedimiento para su preparacion y su uso como medicamentos. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0288852B1 (es) |
AT (1) | ATE92046T1 (es) |
DE (1) | DE3882573T2 (es) |
ES (1) | ES2058167T3 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6075144A (en) * | 1987-04-20 | 2000-06-13 | Hoechst Marion Roussel, Inc. | 9-hydroxyamino tetrahydroacridine and related compounds |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3318896A (en) * | 1963-12-05 | 1967-05-09 | Squibb & Sons Inc | Production of 12-substituted-6, 7, 8, 9, 10, 11-hexahydrocycloocta[b]quinolines |
US4550113A (en) * | 1982-08-19 | 1985-10-29 | Nauchno-Issledovatelsky Institut Po Biologicheskikm Ispytaniyam Khimicheskikh Soedineny | 9-Amino-2,3,5,6,7,8-hexahydro-1H-cyclopenta(b)quinoline monohydrate hydrochloride as stimulant of neuro-muscular transmission of smooth muscles |
EP0179383B1 (en) * | 1984-10-25 | 1991-05-29 | Hoechst-Roussel Pharmaceuticals Incorporated | 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments |
-
1988
- 1988-04-16 AT AT88106108T patent/ATE92046T1/de not_active IP Right Cessation
- 1988-04-16 ES ES88106108T patent/ES2058167T3/es not_active Expired - Lifetime
- 1988-04-16 DE DE88106108T patent/DE3882573T2/de not_active Expired - Fee Related
- 1988-04-16 EP EP88106108A patent/EP0288852B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE3882573D1 (de) | 1993-09-02 |
EP0288852B1 (en) | 1993-07-28 |
ATE92046T1 (de) | 1993-08-15 |
EP0288852A1 (en) | 1988-11-02 |
DE3882573T2 (de) | 1993-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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