ES2055743T3 - Procedimiento de reticulacion del colageno por introduccion de grupos azidas asi como los tejidos y biomateriales obtenidos por aplicacion del procedimiento. - Google Patents

Procedimiento de reticulacion del colageno por introduccion de grupos azidas asi como los tejidos y biomateriales obtenidos por aplicacion del procedimiento.

Info

Publication number
ES2055743T3
ES2055743T3 ES88420240T ES88420240T ES2055743T3 ES 2055743 T3 ES2055743 T3 ES 2055743T3 ES 88420240 T ES88420240 T ES 88420240T ES 88420240 T ES88420240 T ES 88420240T ES 2055743 T3 ES2055743 T3 ES 2055743T3
Authority
ES
Spain
Prior art keywords
groups
procedure
collagen
azid
tissues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88420240T
Other languages
English (en)
Inventor
Herve Petite
Philippe Menasche
Alain Huc
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
BASF Beauty Care Solutions France SAS
Original Assignee
Coletica SA
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coletica SA, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Coletica SA
Application granted granted Critical
Publication of ES2055743T3 publication Critical patent/ES2055743T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/08—Collagen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Developmental Biology & Embryology (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)

Abstract

ESTE PROCEDIMIENTO, QUE COMPORTA ESENCIALMENTE LAS ETAPAS SIGUIENTES: - ESTERIFICACION DE LOS GRUPOS ACIDOS LIBRES DE COLAGENO. -TRANSFORMACION DE LOS GRUPOS ESTERIFICADOS EN GRUPOS HIDRACIDOS. -TRANSFORMACION DE LOS GRUPOS HIDRACIDOS EN GRUPOS AZIDOS POR ACCION DEL ACIDO NITROSO. SE CARACTERIZA PORQUE CADA ETAPA ESTA SEPARADA POR UN ACLARADO CON SOLUCION ACUOSA DE SAL, Y PORQUE LA ETAPA DE TRANSFORMACION DE LOS GRUPOS ESTERIFICADOS EN AGRUPAMIENTOS AZIDOS Y LA ETAPA DE TRANSFORMACION DE LOS AGRUPAMIENTOS HIDRAZIDOS EN GRUPOS AZIDOS POR ACCION DEL ACIDO NITROSO, SE EFECTUAN EN PRESENCIA DE SAL.
ES88420240T 1987-07-08 1988-07-08 Procedimiento de reticulacion del colageno por introduccion de grupos azidas asi como los tejidos y biomateriales obtenidos por aplicacion del procedimiento. Expired - Lifetime ES2055743T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8710317A FR2617855B1 (fr) 1987-07-08 1987-07-08 Procede de reticulation du collagene par introduction de groupes azides ainsi que les tissus et biomateriaux obtenus par mise en oeuvre du procede

Publications (1)

Publication Number Publication Date
ES2055743T3 true ES2055743T3 (es) 1994-09-01

Family

ID=9353383

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88420240T Expired - Lifetime ES2055743T3 (es) 1987-07-08 1988-07-08 Procedimiento de reticulacion del colageno por introduccion de grupos azidas asi como los tejidos y biomateriales obtenidos por aplicacion del procedimiento.

Country Status (6)

Country Link
US (1) US4958008A (es)
EP (1) EP0301977B1 (es)
AT (1) ATE82305T1 (es)
DE (1) DE3875841T2 (es)
ES (1) ES2055743T3 (es)
FR (1) FR2617855B1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2645870B1 (fr) * 1989-04-12 1993-01-22 Bioetica Sa Procede de reticulation du collagene par le diphenylphosphorylazide, collagene reticule ainsi obtenu et biomateriaux a base de collagene ainsi reticules
US5833665A (en) 1990-06-14 1998-11-10 Integra Lifesciences I, Ltd. Polyurethane-biopolymer composite
AU7668894A (en) * 1993-08-13 1995-03-14 Vitaphore Corporation Hydrogel-based microsphere drug delivery systems
US5487895A (en) * 1993-08-13 1996-01-30 Vitaphore Corporation Method for forming controlled release polymeric substrate
IL107578A (en) * 1993-11-11 1998-07-15 Yissum Res Dev Co Topical antibacterial preparation comprising silver sulfadiazine and collagen
US5857375A (en) * 1995-05-31 1999-01-12 M. S. Willett, Inc. Can end stripper and part ejector
US5782931A (en) * 1996-07-30 1998-07-21 Baxter International Inc. Methods for mitigating calcification and improving durability in glutaraldehyde-fixed bioprostheses and articles manufactured by such methods
US6214054B1 (en) 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
US6878168B2 (en) 2002-01-03 2005-04-12 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
ATE430593T1 (de) * 2003-10-28 2009-05-15 Medtronic Inc Verfahren zur herstellung von vernetzten materialien und bioprothetischen vorrichtungen
CA2518298A1 (fr) * 2005-09-06 2007-03-06 Chaimed Technologies Inc. Polymeres biodegradables, leur preparation et leur usage pour la fabrication de pansements
CN101626682B (zh) 2006-10-27 2014-04-16 爱德华兹生命科学公司 用于外科植入的生物组织
US9101691B2 (en) 2007-06-11 2015-08-11 Edwards Lifesciences Corporation Methods for pre-stressing and capping bioprosthetic tissue
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
NZ602066A (en) 2010-03-23 2013-09-27 Edwards Lifesciences Corp Methods of conditioning sheet bioprosthetic tissue
US8906601B2 (en) 2010-06-17 2014-12-09 Edwardss Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
US9351829B2 (en) 2010-11-17 2016-05-31 Edwards Lifesciences Corporation Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability
US10238771B2 (en) 2012-11-08 2019-03-26 Edwards Lifesciences Corporation Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
US9615922B2 (en) 2013-09-30 2017-04-11 Edwards Lifesciences Corporation Method and apparatus for preparing a contoured biological tissue
US10959839B2 (en) 2013-10-08 2021-03-30 Edwards Lifesciences Corporation Method for directing cellular migration patterns on a biological tissue
EP3852683B1 (en) 2018-11-01 2024-05-29 Edwards Lifesciences Corporation Transcatheter pulmonic regenerative valve

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3293237A (en) * 1962-11-30 1966-12-20 Charles J W Wiegand Process of solubilizing native collagen by reacting said collagen with a stoichiometric amount of a mineral acid
US3443261A (en) * 1967-09-01 1969-05-13 Fmc Corp Prosthetic structures from microcrystalline collagen
FR2153667A6 (en) * 1971-09-20 1973-05-04 Davidovits Joseph Synthetic micro porous products - from collagen extracted with nitric acid and then precipitated
US4280954A (en) * 1975-07-15 1981-07-28 Massachusetts Institute Of Technology Crosslinked collagen-mucopolysaccharide composite materials
FR2559666B1 (fr) * 1984-02-21 1986-08-08 Tech Cuir Centre Procede de fabrication de tubes de collagene, notamment de tubes de faibles diametres, et application des tubes obtenus dans le domaine des protheses vasculaires et des sutures nerveuses

Also Published As

Publication number Publication date
FR2617855A1 (fr) 1989-01-13
ATE82305T1 (de) 1992-11-15
EP0301977A1 (fr) 1989-02-01
EP0301977B1 (fr) 1992-11-11
US4958008A (en) 1990-09-18
DE3875841T2 (de) 1993-04-08
FR2617855B1 (fr) 1992-02-21
DE3875841D1 (de) 1992-12-17

Similar Documents

Publication Publication Date Title
ES2055743T3 (es) Procedimiento de reticulacion del colageno por introduccion de grupos azidas asi como los tejidos y biomateriales obtenidos por aplicacion del procedimiento.
DE68918285D1 (de) Methode für behandlung von transplantaten vor transplantationen.
ES2035003T3 (es) Procedimiento para la deformacion duradera del cabello.
SE7512608L (sv) Forfarande for framstellning av heterologa artertransplantat
NO942763D0 (no) Fremgangsmåte for fremstilling av en vann-ulöselig bioforlikelig film
ATE75779T1 (de) Verfahren zur herstellung von optisch aktiven cyanhydrinen.
ATE1826T1 (de) Verfahren zur bleiche von zellstoffen mittels organischer persaeure.
ATE944T1 (de) Verfahren zur herstellung von knochenersatzmaterial mit verbesserter biologischer stabilitaet auf der basis von kollagen und das erhaltene knochenersatzmaterial.
GB915066A (en) Collagen article and the manufacture thereof
ATE106754T1 (de) Verfahren zur herstellung von rinder-pericard- materialien und ihre verwendung.
DE3781959D1 (de) Verfahren zum herstellen von individuell vernetzten fasern.
EP0212881A1 (en) Antithrombogenic medical material
JPS6417649A (en) Preparation of antithrombogenic cellulose
NO954858L (no) Fremgangsmåte for fremstilling av en biodegraderbar, hydrofobisk og transparent film og film oppnådd ved fremgangsmåten
MX169354B (es) Procedimiento para el tratamiento de pieles
DE3855002D1 (de) Verfahren zur Herstellung von Dodecahydro-3a,6,6,9a-tetramethylnaphto(2,1-b)furan
ES2081908T3 (es) Procedimiento para descomponer jabon utilizando un tratamiento a alta temperatura.
JPS5777310A (en) Chitin fiber and its production
FR2029155A5 (en) Prosthetic vessels of high biological - permeability
ATE32718T1 (de) Verfahren zur herstellung von (s)glyceraldehydacetonid.
NO953397D0 (no) Fremgangsmåte og anlegg for fremstilling av celluloseavlut
ATE2895T1 (de) Verfahren zur herstellung von 4-hydroxy-carbazol.
ATE42087T1 (de) Verfahren zur herstellung von dichtem wasserfreiem natriumcarbonat und nach diesem verfahren hergestelltes dichtes wasserfreies natriumcarbonat.
GB900181A (en) Preparation of collagenous polymers
DE3370498D1 (en) Process for the anti-felt treatment of keratinous fibres consisting of a basic oxidation catalyzed by a metal salt, and fibres obtained according to the process

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 301977

Country of ref document: ES