ES2052059T3 - Procedimiento para la obtencion de tiocompuestos. - Google Patents

Procedimiento para la obtencion de tiocompuestos.

Info

Publication number
ES2052059T3
ES2052059T3 ES89810170T ES89810170T ES2052059T3 ES 2052059 T3 ES2052059 T3 ES 2052059T3 ES 89810170 T ES89810170 T ES 89810170T ES 89810170 T ES89810170 T ES 89810170T ES 2052059 T3 ES2052059 T3 ES 2052059T3
Authority
ES
Spain
Prior art keywords
lower alkyl
thiocomposites
procedure
obtaining
halo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89810170T
Other languages
English (en)
Inventor
Pier Giorgio Dr Ferrini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2052059T3 publication Critical patent/ES2052059T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Mechanical Coupling Of Light Guides (AREA)

Abstract

DERIVADOS DE BENZO (B) TIOFENOS DE LA FORMULA I, SUS TAUTOMEROS Y SALES, DONDE EL INDICE N ES 0, 1 O 2, ALK SIGNIFICA BAJO ALQUILO, AR SIGNIFICA FENILO, NAFTILO O UN RESTO HETEROARILO CON SEIS O CINCO MIEMBROS, MONOCICLICO, DONDE EL RESTO AROMATICO ES UN HALOGENO, HALOGENO BAJO ALQUILO, BAJO ALQUILO NO SUSTITUIDO O SUSTITUIDO UNA O MAS VECES Y/O NITRO SUSTITUIDO Y EL ARILLO A ESTA NO SUSTITUIDO O SUSTITUIDO UNA O MAS VECES POR BAJO ALQUILO, BAJO ALCOXI, BAJO ALQUILTIO, BAJO ALCANSULFINILO, BAJO ALCANSULFONILO, HALOGENOBAJO ALQUILO, HALOGENO Y/O NITRO, PUEDE UTILIZARSE POR EJEMPLO COMO SUSTANCIA ACTIVADORA DE MEDICAMENTOS.
ES89810170T 1988-03-16 1989-03-07 Procedimiento para la obtencion de tiocompuestos. Expired - Lifetime ES2052059T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH99888 1988-03-16

Publications (1)

Publication Number Publication Date
ES2052059T3 true ES2052059T3 (es) 1994-07-01

Family

ID=4200067

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89810170T Expired - Lifetime ES2052059T3 (es) 1988-03-16 1989-03-07 Procedimiento para la obtencion de tiocompuestos.

Country Status (10)

Country Link
US (2) US5051421A (es)
EP (1) EP0336886B1 (es)
JP (1) JPH01308276A (es)
AT (1) ATE79876T1 (es)
DE (1) DE58902111D1 (es)
DK (1) DK126989A (es)
ES (1) ES2052059T3 (es)
GR (1) GR3005857T3 (es)
IE (1) IE890828L (es)
PT (1) PT90002B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5436246A (en) * 1992-09-17 1995-07-25 Merrell Dow Pharmaceuticals Inc. Serotonin receptor agents
CN1073563C (zh) * 1994-04-11 2001-10-24 中外制药株式会社 4,6－二叔丁基－2,3－二氢苯并噻吩衍生物
FR2793245B1 (fr) * 1999-05-05 2002-10-11 Adir Nouveaux composes pyridiniques ou piperidiniques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE339235B (es) * 1965-06-01 1971-10-04 Haessle Ab
US4514415A (en) * 1981-10-28 1985-04-30 Ciba Geigy Corporation Benzofuran-2(3H)-ones used as anti-inflammatory agents
US4663344A (en) * 1985-03-11 1987-05-05 Merck & Co., Inc. Anti-inflammatory and analgesic 3-hydroxybenzo[b]thiophene derivatives, compositions, and method of use therefor

Also Published As

Publication number Publication date
EP0336886B1 (de) 1992-08-26
IE890828L (en) 1989-09-16
GR3005857T3 (es) 1993-06-07
EP0336886A1 (de) 1989-10-11
ATE79876T1 (de) 1992-09-15
PT90002B (pt) 1994-06-30
PT90002A (pt) 1989-11-10
DK126989D0 (da) 1989-03-15
US5051421A (en) 1991-09-24
DK126989A (da) 1989-09-17
DE58902111D1 (de) 1992-10-01
US5147889A (en) 1992-09-15
JPH01308276A (ja) 1989-12-12

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