ATE50256T1 - Hypoglycemische thiazolidinedione. - Google Patents

Hypoglycemische thiazolidinedione.

Info

Publication number
ATE50256T1
ATE50256T1 AT86303648T AT86303648T ATE50256T1 AT E50256 T1 ATE50256 T1 AT E50256T1 AT 86303648 T AT86303648 T AT 86303648T AT 86303648 T AT86303648 T AT 86303648T AT E50256 T1 ATE50256 T1 AT E50256T1
Authority
AT
Austria
Prior art keywords
benzo
hypoglycemic
dihydro
hypoglycemic thiazolidinediones
thiazolidinediones
Prior art date
Application number
AT86303648T
Other languages
English (en)
Inventor
James Frederick Eggler
Michael Ross Johnson
Gerald Fagan Holland
Robert Alfred Volkmann
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE50256T1 publication Critical patent/ATE50256T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
AT86303648T 1985-05-21 1986-05-14 Hypoglycemische thiazolidinedione. ATE50256T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1985/000962 WO1986007056A1 (en) 1985-05-21 1985-05-21 Hypoglycemic thiazolidinediones
EP86303648A EP0207605B1 (de) 1985-05-21 1986-05-14 Hypoglycémische Thiazolidinedione

Publications (1)

Publication Number Publication Date
ATE50256T1 true ATE50256T1 (de) 1990-02-15

Family

ID=22188690

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86303648T ATE50256T1 (de) 1985-05-21 1986-05-14 Hypoglycemische thiazolidinedione.

Country Status (26)

Country Link
US (1) US4703052A (de)
EP (1) EP0207605B1 (de)
JP (1) JPS61271287A (de)
KR (1) KR870000903B1 (de)
CN (1) CN1007248B (de)
AT (1) ATE50256T1 (de)
AU (2) AU560179B2 (de)
CA (1) CA1279320C (de)
DD (1) DD261154A5 (de)
DE (1) DE3668892D1 (de)
DK (1) DK233586A (de)
EG (1) EG18043A (de)
ES (1) ES8707210A1 (de)
FI (1) FI89268C (de)
GR (1) GR861297B (de)
HU (1) HU210339B (de)
IE (1) IE58674B1 (de)
IL (1) IL78831A (de)
MY (1) MY108496A (de)
NO (1) NO166448C (de)
PH (2) PH22313A (de)
PL (1) PL147479B1 (de)
PT (1) PT82610B (de)
WO (1) WO1986007056A1 (de)
YU (1) YU44573B (de)
ZA (1) ZA863762B (de)

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US5053420A (en) * 1989-10-13 1991-10-01 Pershadsingh Harrihar A Thiazolidine derivatives for the treatment of hypertension
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5036079A (en) * 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US5089637A (en) * 1990-03-21 1992-02-18 Pfizer Inc. Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde
EP0454501B1 (de) * 1990-04-27 2001-09-05 Sankyo Company Limited Benzylidenthiazolidinderivate, ihre Herstellung und ihre Anwendung als Lipidperoxid-Inhibitoren
US5037842A (en) * 1990-06-05 1991-08-06 Pfizer Inc. Oxa- and thiazolidinedione hypoglycemic and hypocholesterolemic agents
US5089514A (en) * 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
AU645112B2 (en) * 1990-08-23 1994-01-06 Pfizer Inc. Hypoglycemic hydroxyurea derivatives
US5158966A (en) * 1991-02-22 1992-10-27 The University Of Colorado Foundation, Inc. Method of treating type i diabetes
TW222626B (de) 1991-07-22 1994-04-21 Pfizer
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US5498621A (en) * 1992-05-01 1996-03-12 Pfizer Inc. Oxazolidinedione hypoglycemic agents
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US5594016A (en) * 1992-12-28 1997-01-14 Mitsubishi Chemical Corporation Naphthalene derivatives
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US5401761A (en) * 1993-12-09 1995-03-28 Pfizer, Inc. Thiazolidinedione hypoglycemic agents
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US6251928B1 (en) * 1994-03-16 2001-06-26 Eli Lilly And Company Treatment of alzheimer's disease employing inhibitors of cathepsin D
US5594015A (en) * 1994-06-22 1997-01-14 Regents Of The University Of California Thiazolidine derivatives for the treatment of psoriasis
US5641796A (en) * 1994-11-01 1997-06-24 Eli Lilly And Company Oral hypoglycemic agents
US5708012A (en) * 1995-04-28 1998-01-13 Sankyo Company, Limited Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of insulin resistant subjects with normal glucose tolerance in order to prevent or delay the onset of noninsulin-dependent mellitus
TW474809B (en) * 1995-07-03 2002-02-01 Sankyo Co A pharmaceutical composition for arteriosclerosis or xanthoma consisting of HMG-CoA reductase inhibitors and insulin sensitizers
GB9604340D0 (en) * 1996-02-29 1996-05-01 Unilever Plc Antiperspirant aerosol composition and method of making same
NZ314406A (en) * 1996-03-18 2000-12-22 Sankyo Co Treatment or prophylaxis of pancreatitis with a medicament containing an insulin sensitiser including oxazoles and thiazoles
WO1997037970A1 (fr) * 1996-04-04 1997-10-16 Sankyo Company, Limited Derives d'acide phenylalkylcarboxylique
CA2257284C (en) * 1996-05-31 2005-10-04 Sankyo Company Limited Remedy for autoimmune diseases
EP1006794B1 (de) * 1997-03-12 2007-11-28 Robert W. Esmond Verfahren zur behandlung oder prävention der alzheimerischen krankheit
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HUP9902721A2 (hu) * 1997-11-25 1999-12-28 The Procter & Gamble Co. Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület
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US5968960A (en) * 1999-01-14 1999-10-19 The Regents Of The University Of California Use of thiazolidinediones to ameliorate the adverse consequences of myocardial ischemia on myocardial function and metabolism
JP2001072592A (ja) 1999-07-01 2001-03-21 Kyowa Hakko Kogyo Co Ltd テロメラーゼ阻害剤
WO2001007031A1 (fr) * 1999-07-26 2001-02-01 Shionogi & Co., Ltd. Derives de benzene, compositions immunostimulantes ou agents de retablissement de la pharmacosensibilite les contenant
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US6559188B1 (en) 1999-09-17 2003-05-06 Novartis Ag Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
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US6958355B2 (en) * 2000-04-24 2005-10-25 Aryx Therapeutics, Inc. Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
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US6680387B2 (en) * 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
KR100711757B1 (ko) * 2000-12-22 2007-04-25 재단법인 포항산업과학연구원 폐수처리용 활성화 슬래그 및 이를 이용한 폐수처리방법
US6452014B1 (en) 2000-12-22 2002-09-17 Geron Corporation Telomerase inhibitors and methods of their use
US20060047000A1 (en) * 2001-04-24 2006-03-02 Aryx Therapeutics, Inc. Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
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Also Published As

Publication number Publication date
IE58674B1 (en) 1993-11-03
AU583991B2 (en) 1989-05-11
JPS61271287A (ja) 1986-12-01
IL78831A0 (en) 1986-09-30
EG18043A (en) 1992-11-30
DD261154A5 (de) 1988-10-19
WO1986007056A1 (en) 1986-12-04
PL147479B1 (en) 1989-06-30
KR870000903B1 (ko) 1987-05-04
NO870241D0 (no) 1987-01-20
EP0207605B1 (de) 1990-02-07
FI870219A0 (fi) 1987-01-20
HUT45247A (en) 1988-06-28
DK233586D0 (da) 1986-05-20
PT82610B (pt) 1988-11-30
EP0207605A1 (de) 1987-01-07
YU44573B (en) 1990-10-31
DE3668892D1 (en) 1990-03-15
HU210339B (en) 1995-03-28
NO870241L (no) 1987-03-20
CA1279320C (en) 1991-01-22
PH22313A (en) 1988-07-29
KR860009010A (ko) 1986-12-19
YU83786A (en) 1987-12-31
ES8707210A1 (es) 1987-07-16
MY108496A (en) 1996-10-31
CN1007248B (zh) 1990-03-21
ZA863762B (en) 1988-05-25
FI89268C (fi) 1993-09-10
IL78831A (en) 1990-11-29
GR861297B (en) 1986-09-16
FI89268B (fi) 1993-05-31
JPH0586953B2 (de) 1993-12-14
ES555147A0 (es) 1987-07-16
CN86104075A (zh) 1987-03-11
AU5758086A (en) 1987-01-08
AU7507487A (en) 1987-10-15
AU560179B2 (en) 1987-04-02
US4703052A (en) 1987-10-27
PH25226A (en) 1991-03-27
PT82610A (en) 1986-06-01
IE861336L (en) 1986-11-21
DK233586A (da) 1986-11-22
FI870219A (fi) 1987-01-20
NO166448B (no) 1991-04-15
NO166448C (no) 1991-07-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee