ES2044091T3 - Formulaciones anti-neoplasticas. - Google Patents

Formulaciones anti-neoplasticas.

Info

Publication number
ES2044091T3
ES2044091T3 ES89302599T ES89302599T ES2044091T3 ES 2044091 T3 ES2044091 T3 ES 2044091T3 ES 89302599 T ES89302599 T ES 89302599T ES 89302599 T ES89302599 T ES 89302599T ES 2044091 T3 ES2044091 T3 ES 2044091T3
Authority
ES
Spain
Prior art keywords
carboplatin
solution
lyophilisate
reconstituting
neoplastic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89302599T
Other languages
English (en)
Inventor
Harold Phillip Levius
Yisrael Geffen
Benjamin Sklarz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abic Ltd
Original Assignee
Abic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abic Ltd filed Critical Abic Ltd
Application granted granted Critical
Publication of ES2044091T3 publication Critical patent/ES2044091T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

EL CARBOPLATINO SE PRODUCE CONVENCIONALMENTE EN SOLUCIONES INYECTABLES EXTEMPORANEAS POR RECONSTITUCION DE UN LIOFILIZADO CON AGUA O UNA SOLUCION DE DEXTROSA O SALINA. ESTO ES DIFICIL Y PELIGROSO Y LAS SOLUCIONES FORMADAS SON INESTABLES. LA INVENCION PROPORCIONA UNA SOLUCION ACUOSA, INYECTABLE DE CARBOPLATINO, ESTABLE Y LISTA PARA USAR HECHA SIN RECONSTRUIR UN LIOFILIZADO, ES DECIR, A PARTIR DE CARBOPLATINO NO LIOFILIZADO. LA SOLUCION PREFERIBLEMENTE CONTIENE DE 10 A 15 MG/ML DE CARBOPLATINO, UN POLIOL (HASTA 10% DE MANITOL) Y UN CONSERVANTE, PERO ESTA EXENTA DE SAL Y TIENE PREFERIBLEMENTE UN PH ENTRE 5 Y 7.
ES89302599T 1988-03-20 1989-03-16 Formulaciones anti-neoplasticas. Expired - Lifetime ES2044091T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL85790A IL85790A0 (en) 1988-03-20 1988-03-20 Solution of carboplatin

Publications (1)

Publication Number Publication Date
ES2044091T3 true ES2044091T3 (es) 1994-01-01

Family

ID=11058683

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89302599T Expired - Lifetime ES2044091T3 (es) 1988-03-20 1989-03-16 Formulaciones anti-neoplasticas.

Country Status (7)

Country Link
EP (1) EP0334551B1 (es)
AT (1) ATE80296T1 (es)
AU (1) AU623632B2 (es)
DE (1) DE68902755T2 (es)
ES (1) ES2044091T3 (es)
IL (1) IL85790A0 (es)
ZA (1) ZA891360B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5455270A (en) * 1993-08-11 1995-10-03 Bristol-Myers Squibb Co. Stabilized solutions of platinum(II) antitumor agents
ES2160117T3 (es) * 1994-02-07 2001-11-01 Pliva Pharmaceutical Industry Composicion farmaceutica antitumoral a base de carboplatino, y su procedimiento de produccion.
EP3826613A4 (en) * 2018-08-31 2022-05-04 Sun Pharmaceutical Industries Limited PARENTERAL DOSAGE FORM OF CARBOPLATIN

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1119954A (en) * 1978-05-30 1982-03-16 Edmund S. Granatek Aqueous solution of cisplatin
US4571335A (en) * 1983-06-17 1986-02-18 Taylor Robert C Method of inhibiting herpetic lesions by the use of platinum coordination compounds

Also Published As

Publication number Publication date
AU623632B2 (en) 1992-05-21
EP0334551B1 (en) 1992-09-09
ATE80296T1 (de) 1992-09-15
IL85790A0 (en) 1988-09-30
AU3026589A (en) 1989-09-21
ZA891360B (en) 1989-12-27
DE68902755D1 (de) 1992-10-15
EP0334551A1 (en) 1989-09-27
DE68902755T2 (de) 1993-01-14

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