ES2039460T3 - Un procedimiento para producir una solucion inyectable de glicosido de antraciclina. - Google Patents
Un procedimiento para producir una solucion inyectable de glicosido de antraciclina.Info
- Publication number
- ES2039460T3 ES2039460T3 ES198787310632T ES87310632T ES2039460T3 ES 2039460 T3 ES2039460 T3 ES 2039460T3 ES 198787310632 T ES198787310632 T ES 198787310632T ES 87310632 T ES87310632 T ES 87310632T ES 2039460 T3 ES2039460 T3 ES 2039460T3
- Authority
- ES
- Spain
- Prior art keywords
- anthracicline
- glycoside
- procedure
- producing
- injectable solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229930182470 glycoside Natural products 0.000 title abstract 2
- 150000002338 glycosides Chemical class 0.000 title abstract 2
- 229940102223 injectable solution Drugs 0.000 title 1
- 239000002510 pyrogen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
UN DISOLUCION DE GLICOSIDO DE ANTRACICLINA INYECTABLE, ESTABLE AL ALMACENAMIENTO, ESTERIL, SIN PIROGENOS, CONSTA ESENCIALMENTE DE UNA SAL FISIOLOGICAMENTE ACEPTABLE DE UN GLICOSIDO DE ANTRACICLINA DISUELTO EN UN DISOLVENTE DEL MISMO FISIOLOGICAMENTE ACEPTABLE, QUE NO HA SIDO RECONSTITUIDA A PARTIR DE UN LIOFILIZADO, Y EL PH DE LA CUAL SE HA AJUSTADO A 2,5-4,0.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB868629193A GB8629193D0 (en) | 1986-12-05 | 1986-12-05 | Injectable ready-to-use solutions |
US6465387A | 1987-06-22 | 1987-06-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2039460T3 true ES2039460T3 (es) | 1993-10-01 |
Family
ID=26291656
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95101919T Expired - Lifetime ES2198424T3 (es) | 1986-12-05 | 1987-12-03 | Soluciones inyectables listas para el empleo que contienen doxorrubicina. |
ES91102986T Expired - Lifetime ES2082023T3 (es) | 1986-12-05 | 1987-12-03 | Soluciones inyectables listas para su utilizacion que contienen un agente antitumoral del tipo antraciclina glucosido. |
ES198787310632T Expired - Lifetime ES2039460T3 (es) | 1986-12-05 | 1987-12-03 | Un procedimiento para producir una solucion inyectable de glicosido de antraciclina. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95101919T Expired - Lifetime ES2198424T3 (es) | 1986-12-05 | 1987-12-03 | Soluciones inyectables listas para el empleo que contienen doxorrubicina. |
ES91102986T Expired - Lifetime ES2082023T3 (es) | 1986-12-05 | 1987-12-03 | Soluciones inyectables listas para su utilizacion que contienen un agente antitumoral del tipo antraciclina glucosido. |
Country Status (22)
Country | Link |
---|---|
EP (4) | EP0438183B1 (es) |
JP (1) | JP2621255B2 (es) |
KR (2) | KR0158672B1 (es) |
CN (1) | CN1058391C (es) |
AT (2) | ATE240108T1 (es) |
AU (1) | AU632036B2 (es) |
BE (1) | BE1000540A5 (es) |
CH (1) | CH680494A5 (es) |
DE (4) | DE3751589T2 (es) |
DK (1) | DK175815B1 (es) |
ES (3) | ES2198424T3 (es) |
FI (1) | FI91710C (es) |
FR (1) | FR2607702B1 (es) |
GB (1) | GB2200047B (es) |
GR (2) | GR871846B (es) |
HK (3) | HK39591A (es) |
IT (1) | IT1226072B (es) |
NL (1) | NL8702914A (es) |
NO (1) | NO175802C (es) |
PT (1) | PT86285B (es) |
SE (1) | SE512881C2 (es) |
SG (1) | SG36591G (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8519452D0 (en) * | 1985-08-02 | 1985-09-11 | Erba Farmitalia | Injectable solutions |
DE10300323A1 (de) * | 2003-01-09 | 2004-10-14 | Baxter Healthcare S.A. | Sicherheitsbehälter mit erhöhter Bruch und Splitterfestigkeit sowie kontaminationsfreier Außenfläche für biologisch aktive Substanzen und Verfahren zu deren Herstellung |
KR100921199B1 (ko) * | 2001-05-11 | 2009-10-13 | 미쓰비시 타나베 파마 코퍼레이션 | 안정하고 고농도인 피라졸론 유도체를 포함하는 주사제 |
AU2006213440A1 (en) * | 2005-02-11 | 2006-08-17 | Dabur Pharma Limited | Stabilized anthracycline glycoside pharmaceutical compositions |
KR20070088447A (ko) * | 2005-05-11 | 2007-08-29 | 시코르, 인크. | 안정한 동결건조된 안트라사이클린 글리코시드 |
EP2184066B1 (en) * | 2007-09-04 | 2013-11-06 | Meiji Seika Pharma Co., Ltd. | Injection, injection solution and injection kit preparation |
EP2174651A1 (en) * | 2008-10-09 | 2010-04-14 | Charité-Universitätsmedizin Berlin (Charité) | A polymer-free hydrogel |
CN102614118B (zh) * | 2012-03-15 | 2014-04-30 | 北京协和药厂 | 注射用盐酸表柔比星制剂的制备方法及制剂 |
CN111617030B (zh) * | 2020-05-22 | 2021-09-07 | 广东药科大学 | 壳寡糖口服液及其在制备减肥药物中的应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4177264A (en) * | 1977-10-17 | 1979-12-04 | Sri International | N-benzyl anthracyclines |
GB2007645B (en) * | 1977-10-17 | 1982-05-12 | Stanford Res Inst Int | Benzyl anthracyclines and pharmaceutical compositions containing them |
GB2187311B (en) * | 1984-07-27 | 1988-02-10 | Ae Plc | Automatic vehicle speed control system |
GB8426672D0 (en) * | 1984-10-22 | 1984-11-28 | Erba Farmitalia | Pharmaceutical compositions |
GB8519452D0 (en) * | 1985-08-02 | 1985-09-11 | Erba Farmitalia | Injectable solutions |
JPH0655667A (ja) * | 1992-08-06 | 1994-03-01 | Nippon Zeon Co Ltd | 複合成形体 |
-
1987
- 1987-12-03 EP EP91102986A patent/EP0438183B1/en not_active Revoked
- 1987-12-03 FR FR878716814A patent/FR2607702B1/fr not_active Expired - Lifetime
- 1987-12-03 CH CH4724/87A patent/CH680494A5/de not_active IP Right Cessation
- 1987-12-03 PT PT86285A patent/PT86285B/pt unknown
- 1987-12-03 DE DE3751589T patent/DE3751589T2/de not_active Revoked
- 1987-12-03 SE SE8704849A patent/SE512881C2/sv not_active IP Right Cessation
- 1987-12-03 DE DE3752368T patent/DE3752368T2/de not_active Revoked
- 1987-12-03 AU AU82059/87A patent/AU632036B2/en not_active Expired
- 1987-12-03 EP EP87310632A patent/EP0273603B1/en not_active Expired - Lifetime
- 1987-12-03 AT AT95101919T patent/ATE240108T1/de not_active IP Right Cessation
- 1987-12-03 KR KR1019870013744Q patent/KR0158672B1/ko active
- 1987-12-03 ES ES95101919T patent/ES2198424T3/es not_active Expired - Lifetime
- 1987-12-03 DE DE19873741037 patent/DE3741037A1/de not_active Withdrawn
- 1987-12-03 AT AT91102986T patent/ATE129896T1/de not_active IP Right Cessation
- 1987-12-03 DE DE8787310632T patent/DE3777365D1/de not_active Expired - Lifetime
- 1987-12-03 JP JP62304699A patent/JP2621255B2/ja not_active Expired - Lifetime
- 1987-12-03 NO NO875055A patent/NO175802C/no not_active IP Right Cessation
- 1987-12-03 KR KR1019870013744A patent/KR960007861B1/ko not_active IP Right Cessation
- 1987-12-03 ES ES91102986T patent/ES2082023T3/es not_active Expired - Lifetime
- 1987-12-03 NL NL8702914A patent/NL8702914A/nl not_active Application Discontinuation
- 1987-12-03 ES ES198787310632T patent/ES2039460T3/es not_active Expired - Lifetime
- 1987-12-03 CN CN87108225A patent/CN1058391C/zh not_active Expired - Lifetime
- 1987-12-03 EP EP02025856A patent/EP1283044A3/en not_active Withdrawn
- 1987-12-03 GR GR871846A patent/GR871846B/el unknown
- 1987-12-03 IT IT8722869A patent/IT1226072B/it active
- 1987-12-03 FI FI875340A patent/FI91710C/fi not_active IP Right Cessation
- 1987-12-03 EP EP95101919A patent/EP0659435B1/en not_active Revoked
- 1987-12-03 BE BE8701384A patent/BE1000540A5/fr not_active IP Right Cessation
- 1987-12-03 DK DK198706352A patent/DK175815B1/da not_active IP Right Cessation
- 1987-12-03 GB GB8728313A patent/GB2200047B/en not_active Expired - Lifetime
-
1991
- 1991-05-13 SG SG365/91A patent/SG36591G/en unknown
- 1991-05-23 HK HK395/91A patent/HK39591A/xx not_active IP Right Cessation
-
1992
- 1992-04-08 GR GR920400665T patent/GR3004303T3/el unknown
-
1998
- 1998-11-30 HK HK03101548.2A patent/HK1049440A1/zh unknown
- 1998-11-30 HK HK98112442A patent/HK1011288A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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