ES2039318T1 - Metodo de preparacion de beta-aminoacidos quirales. - Google Patents

Metodo de preparacion de beta-aminoacidos quirales.

Info

Publication number
ES2039318T1
ES2039318T1 ES199090870063T ES90870063T ES2039318T1 ES 2039318 T1 ES2039318 T1 ES 2039318T1 ES 199090870063 T ES199090870063 T ES 199090870063T ES 90870063 T ES90870063 T ES 90870063T ES 2039318 T1 ES2039318 T1 ES 2039318T1
Authority
ES
Spain
Prior art keywords
beta
amino acids
preparation
amino
chiral beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
ES199090870063T
Other languages
English (en)
Inventor
John Jeffrey Talley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of ES2039318T1 publication Critical patent/ES2039318T1/es
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION ESTA DIRIGIDA HACIA UNA SINTESIS ASIMETRICA DE BETA-AMINO ACIDOS DONDE SE EFETUA UN DISPOSITIVO CURTIUS DE SUCCIONATOS 2(R)- MONO SUSTITUIDOS, Y EL ISOCIANATO INCIPIENTE SE SEPARA DEL ALCOHOL PRIMARIO O SECUNDARIO. LOS BETA-AMINO ESTERES DE CARBAMATO PROTEGIDOS RESULTANTES SON ENTONCES SAPONIFICADOS PARA PRODUCIR LOS CORRESPONDIENTES BETA-AMINO ACIDOS DE CARBAMATO PROTEGIDO, LOS CUALES SON DESPROTEGIDOS YA QUE POSEEN LA MISMA CONFIGURACION ABSOLUTA QUE LOS AMINO ACIDOS (L).
ES199090870063T 1989-05-01 1990-04-30 Metodo de preparacion de beta-aminoacidos quirales. Pending ES2039318T1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34580889A 1989-05-01 1989-05-01

Publications (1)

Publication Number Publication Date
ES2039318T1 true ES2039318T1 (es) 1993-10-01

Family

ID=23356571

Family Applications (1)

Application Number Title Priority Date Filing Date
ES199090870063T Pending ES2039318T1 (es) 1989-05-01 1990-04-30 Metodo de preparacion de beta-aminoacidos quirales.

Country Status (4)

Country Link
EP (1) EP0396526A3 (es)
JP (1) JPH02306947A (es)
CA (1) CA2015761A1 (es)
ES (1) ES2039318T1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0561758A3 (en) * 1992-03-18 1995-04-05 Monsanto Co Method of preparing optically active homo-beta-amino acids
US5599947A (en) * 1993-01-14 1997-02-04 G. D. Searle & Co. Fatty acid analogs and prodrugs
US5859052A (en) * 1993-01-14 1999-01-12 G. D. Searle & Co. Fatty acid analogs and prodrugs
CA2906830C (en) 2013-03-15 2021-07-06 Protagonist Therapeutics, Inc. Hepcidin analogues and uses therof
EP3143037B1 (en) 2014-05-16 2021-06-23 Protagonist Therapeutics, Inc. Alpha4beta7 integrin thioether peptide antagonists
CN107206254B (zh) 2014-07-17 2021-08-24 领导医疗有限公司 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途
EP3749345A4 (en) 2018-02-08 2022-04-06 Protagonist Therapeutics, Inc. CONJUGATED HEPCIDIN MIMETICS
WO2020198682A1 (en) * 2019-03-28 2020-10-01 Protagonist Therapeutics, Inc. METHODS FOR SYNTHESIZING β-HOMOAMINO ACIDS
PE20230370A1 (es) 2020-01-15 2023-03-06 Janssen Biotech Inc Inhibidores de peptidos del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias
JP7397239B2 (ja) 2020-11-20 2023-12-12 ヤンセン ファーマシューティカ エヌ．ベー． インターロイキン－２３受容体のペプチド阻害剤の組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1166403A (en) * 1967-07-21 1969-10-08 Ici Ltd Process for the manufacture of Amino Acid Derivatives
NZ211872A (en) * 1984-04-27 1989-06-28 Ishihara Sangyo Kaisha Chartreusin derivatives and antitumorous compositions
JPS63503380A (ja) * 1986-01-16 1988-12-08 アボット・ラボラトリーズ ペプチド類似体
US4939288A (en) * 1989-01-23 1990-07-03 Monsanto Company Method of preparing (R)-succinic acid derivatives

Also Published As

Publication number Publication date
EP0396526A2 (en) 1990-11-07
JPH02306947A (ja) 1990-12-20
CA2015761A1 (en) 1990-11-01
EP0396526A3 (en) 1992-04-01

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