ES2039256T3 - Procedimiento para la obtencion de compuestos triciclicos. - Google Patents
Procedimiento para la obtencion de compuestos triciclicos.Info
- Publication number
- ES2039256T3 ES2039256T3 ES198787401562T ES87401562T ES2039256T3 ES 2039256 T3 ES2039256 T3 ES 2039256T3 ES 198787401562 T ES198787401562 T ES 198787401562T ES 87401562 T ES87401562 T ES 87401562T ES 2039256 T3 ES2039256 T3 ES 2039256T3
- Authority
- ES
- Spain
- Prior art keywords
- group
- procedure
- tricyclic compounds
- vinylene
- obtaining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/36—Benzo-cinnolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A LOS NUEVOS DERIVADOS TRICICLICOS AGONISTAS DE RECEPTORES COLINERGICOS. ESTOS COMPUESTOS RESPONDEN A LA FORMULA (I) EN LA CUAL - X REPRESENTA UN GRUPO (CH2)N CON N REPRESENTANDO UN ENTERO IGUAL A 2,3 O 4 O DE NUEVO A UN GRUPO VINILENO O UN GRUPO METIL VINILENO; - R1 Y R2 CONSIDERADOS INDEPENDIENTEMENTE, REPRESENTAN AL HIDROGENO O UN SUSTITUYENTE QUE OCUPA UNA DE LAS POSICIONES LIBRES DEL CICLO BENCENICO Y ELEGIDO ENTRE LOS HALOGENOS, UN GRUPO ALQUILO INFERIOR, UN GRUPO ALCOXI INFERIOR, UN GRUPO HIDROXI, UN GRUPO TIOL, UN GRUPO NITRO, UN GRUPO AMINO EVENTUALMENTE SUSTITUIDO; - Y REPRESENTA EL OXIGENO, EL AZUFRE O UN GRUPO -NH-; - R3 REPRESENTA PRINCIPALMENTE UN GRUPO AMINO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8609681A FR2601011B1 (fr) | 1986-07-03 | 1986-07-03 | Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2039256T3 true ES2039256T3 (es) | 1993-09-16 |
Family
ID=9337042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198787401562T Expired - Lifetime ES2039256T3 (es) | 1986-07-03 | 1987-07-03 | Procedimiento para la obtencion de compuestos triciclicos. |
Country Status (16)
Country | Link |
---|---|
US (1) | US4977152A (es) |
EP (1) | EP0251937B1 (es) |
JP (1) | JPH029866A (es) |
KR (1) | KR880001614A (es) |
AR (1) | AR245123A1 (es) |
AT (1) | ATE60589T1 (es) |
AU (1) | AU602339B2 (es) |
CA (1) | CA1312864C (es) |
DE (1) | DE3767794D1 (es) |
DK (1) | DK162220C (es) |
ES (1) | ES2039256T3 (es) |
FR (1) | FR2601011B1 (es) |
GR (1) | GR3001646T3 (es) |
NZ (1) | NZ220926A (es) |
PT (1) | PT85234B (es) |
ZA (1) | ZA874846B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2625201B1 (fr) * | 1987-12-24 | 1990-06-15 | Sanofi Sa | Nouveaux derives tricycliques agonistes des recepteurs cholinergiques et medicaments en contenant |
US4985560A (en) * | 1990-01-12 | 1991-01-15 | American Home Products Corporation | Pyridazino(4,5-b)indolizines |
US20100210590A1 (en) * | 1995-09-27 | 2010-08-19 | Northwestern University | Compositions and treatments for seizure-related disorders |
EP1430033A4 (en) * | 2001-08-31 | 2004-12-15 | Univ Northwestern | PROTEIN KINASE ANTI-INFLAMMATORY AND INHIBITOR COMPOSITION AND METHOD OF USE |
KR100422589B1 (ko) * | 2001-11-20 | 2004-03-16 | (주)경인양행 | 셀룰로오스 섬유 또는 셀룰로오스 혼방섬유의 염색 방법 |
ATE523199T1 (de) * | 2004-11-02 | 2011-09-15 | Univ Northwestern | Pyridazinverbindungen und verfahren |
EP1812408B1 (en) | 2004-11-02 | 2013-10-09 | Northwestern University | Pyridazine compounds, compositions and methods |
CA2650711A1 (en) * | 2006-04-28 | 2007-11-08 | Northwestern University | Compositions and treatments using pyridazine compounds and cholinesterase inhibitors |
CA2650704A1 (en) * | 2006-04-28 | 2007-11-08 | Northwestern University | Salts of pyridazine compounds |
CA2650625A1 (en) | 2006-04-28 | 2007-11-08 | Northwestern University | Formulations containing pyridazine compounds for treating neuroinflammatory diseases |
WO2009089305A1 (en) * | 2008-01-07 | 2009-07-16 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2510997A1 (fr) * | 1981-08-10 | 1983-02-11 | Sanofi Sa | Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant |
FR2619818B1 (fr) * | 1987-09-01 | 1990-01-12 | Sanofi Sa | Imidazo (1,2-b) pyridazines, procede pour leur preparation et compositions pharmaceutiques les contenant |
-
1986
- 1986-07-03 FR FR8609681A patent/FR2601011B1/fr not_active Expired
-
1987
- 1987-07-02 AR AR87308037A patent/AR245123A1/es active
- 1987-07-02 CA CA000541127A patent/CA1312864C/en not_active Expired - Fee Related
- 1987-07-02 PT PT85234A patent/PT85234B/pt not_active IP Right Cessation
- 1987-07-02 AU AU75049/87A patent/AU602339B2/en not_active Ceased
- 1987-07-02 NZ NZ220926A patent/NZ220926A/xx unknown
- 1987-07-02 DK DK340987A patent/DK162220C/da not_active IP Right Cessation
- 1987-07-03 ZA ZA874846A patent/ZA874846B/xx unknown
- 1987-07-03 DE DE8787401562T patent/DE3767794D1/de not_active Expired - Fee Related
- 1987-07-03 KR KR1019870007113A patent/KR880001614A/ko not_active Application Discontinuation
- 1987-07-03 AT AT87401562T patent/ATE60589T1/de not_active IP Right Cessation
- 1987-07-03 ES ES198787401562T patent/ES2039256T3/es not_active Expired - Lifetime
- 1987-07-03 JP JP62166746A patent/JPH029866A/ja active Pending
- 1987-07-03 EP EP87401562A patent/EP0251937B1/fr not_active Expired - Lifetime
-
1990
- 1990-01-25 US US07/471,680 patent/US4977152A/en not_active Expired - Fee Related
-
1991
- 1991-03-21 GR GR91400356T patent/GR3001646T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DK340987D0 (da) | 1987-07-02 |
DK162220B (da) | 1991-09-30 |
KR880001614A (ko) | 1988-04-25 |
JPH029866A (ja) | 1990-01-12 |
ATE60589T1 (de) | 1991-02-15 |
PT85234B (pt) | 1990-04-30 |
DK340987A (da) | 1988-01-04 |
PT85234A (fr) | 1987-08-01 |
CA1312864C (en) | 1993-01-19 |
AU602339B2 (en) | 1990-10-11 |
DE3767794D1 (de) | 1991-03-07 |
DK162220C (da) | 1992-03-02 |
AR245123A1 (es) | 1993-12-30 |
AU7504987A (en) | 1988-01-07 |
NZ220926A (en) | 1989-11-28 |
ZA874846B (en) | 1988-03-30 |
FR2601011A1 (fr) | 1988-01-08 |
EP0251937B1 (fr) | 1991-01-30 |
GR3001646T3 (en) | 1992-11-23 |
FR2601011B1 (fr) | 1988-10-28 |
US4977152A (en) | 1990-12-11 |
EP0251937A1 (fr) | 1988-01-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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