ES2036523T3 - 4-aminoarildihidropiridinlactonas, procedimiento para su obtencion y su empleo en medicamentos. - Google Patents

4-aminoarildihidropiridinlactonas, procedimiento para su obtencion y su empleo en medicamentos.

Info

Publication number
ES2036523T3
ES2036523T3 ES198686117972T ES86117972T ES2036523T3 ES 2036523 T3 ES2036523 T3 ES 2036523T3 ES 198686117972 T ES198686117972 T ES 198686117972T ES 86117972 T ES86117972 T ES 86117972T ES 2036523 T3 ES2036523 T3 ES 2036523T3
Authority
ES
Spain
Prior art keywords
procedure
obtaining
aminoarildihidropiridinlactonas
employment
medicines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198686117972T
Other languages
English (en)
Inventor
Siegfried Dr. Goldmann
Matthias Dr. Schramm
Rainer Prof. Dr. Gross
Gunther Dr. Cno Bayer Italia S.P.A. Thomas
Martin Dr. Bechem
Michael Dr. Kayser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2036523T3 publication Critical patent/ES2036523T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

DESCRIPCION DE 4-AMINOARILDIHIDROPIRIDINAS DE FORMULA (I), CON LA DEFINICION DE LOS SUSTITUYENTES CARACTERIZADOS SEGUN LA DESCRIPCION DE UN PROCEDIMIENTO PARA SU OBTENCION POR REDUCCION DE LA 4-NITROARILDIHIDROPIRIDINA CORRESPONDIENTE Y EVENTUALMENTE TRANSFORMACION ULTERIOR EN EL GRUPO 4-AMINOARILO, ASI COMO SU APLICACION EN MEDICAMENTOS.
ES198686117972T 1986-01-11 1986-12-23 4-aminoarildihidropiridinlactonas, procedimiento para su obtencion y su empleo en medicamentos. Expired - Lifetime ES2036523T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863600596 DE3600596A1 (de) 1986-01-11 1986-01-11 4-aminoaryldihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Publications (1)

Publication Number Publication Date
ES2036523T3 true ES2036523T3 (es) 1993-06-01

Family

ID=6291664

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198686117972T Expired - Lifetime ES2036523T3 (es) 1986-01-11 1986-12-23 4-aminoarildihidropiridinlactonas, procedimiento para su obtencion y su empleo en medicamentos.

Country Status (9)

Country Link
US (1) US4804667A (es)
EP (1) EP0231511B1 (es)
JP (1) JPH0791300B2 (es)
KR (1) KR870007178A (es)
AT (1) ATE62488T1 (es)
CA (1) CA1300627C (es)
DE (2) DE3600596A1 (es)
DK (1) DK10487A (es)
ES (1) ES2036523T3 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868181A (en) * 1986-08-04 1989-09-19 E. I. Du Pont De Nemours And Company 1,4-dihydropyridine derivatives with calcium agonist and alpha1 -antagonist activity
DE3706204A1 (de) * 1987-02-26 1988-09-08 Bayer Ag Benzylaminoaryl-dihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
AU2004272078A1 (en) * 2003-09-10 2005-03-24 Synta Pharmaceuticals Corp. Dihydropyridine compounds for treating or preventing metabolic disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
US4284634A (en) * 1975-07-02 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 1,4-Dihydropyridine derivatives, and pharmaceutical method of the same
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3130041A1 (de) * 1981-07-30 1983-02-17 Bayer Ag, 5090 Leverkusen Dihydropyridine mit positiv inotroper wirkung, neue verbindungen, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
EP0111453A1 (de) * 1982-12-10 1984-06-20 Ciba-Geigy Ag Amid-Verbindungen
DE3410645A1 (de) * 1984-03-23 1985-09-26 Bayer Ag, 5090 Leverkusen L-alkylsubstituierte 1,4-dihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
DK10487A (da) 1987-07-12
DE3678707D1 (de) 1991-05-16
JPS62190187A (ja) 1987-08-20
DK10487D0 (da) 1987-01-09
EP0231511B1 (de) 1991-04-10
JPH0791300B2 (ja) 1995-10-04
DE3600596A1 (de) 1987-07-16
EP0231511A1 (de) 1987-08-12
ATE62488T1 (de) 1991-04-15
CA1300627C (en) 1992-05-12
US4804667A (en) 1989-02-14
KR870007178A (ko) 1987-08-17

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