ES2015433A6 - Procedimientos de preparacion de la sal de piperacina del monotosilato del acido 2,5-dihidroxibencenosulfonico - Google Patents
Procedimientos de preparacion de la sal de piperacina del monotosilato del acido 2,5-dihidroxibencenosulfonicoInfo
- Publication number
- ES2015433A6 ES2015433A6 ES8902754A ES8902754A ES2015433A6 ES 2015433 A6 ES2015433 A6 ES 2015433A6 ES 8902754 A ES8902754 A ES 8902754A ES 8902754 A ES8902754 A ES 8902754A ES 2015433 A6 ES2015433 A6 ES 2015433A6
- Authority
- ES
- Spain
- Prior art keywords
- monotosylate
- salt
- piperazine
- preparing
- dihydroxybenzenesulphonic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/32—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of salts of sulfonic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE LA SAL DE PIPERACINA DEL MOTOSILATO DEL ACIDO 2,5-DIHIDROXIBENCENOSULFONICO. SE CARACTERIZA PORQUE SE UTILIZA COMO MATERIAL DE PARTIDA LA SAL DE DIETILAMINA O LA SAL DE AMONIO DEL ACIDO 2,5-DIHIDROXIBENCENOSULFONICO, LA CUAL ES TOSILADA EN MEDIO AMONIACAL PARA CONDUCIR EN AMBOS CASOS A LA OBTENCION DE LA SAL AMONIO DEL MONOTOSILATO DEL ACIDO 2,5-DIHIDROXIBENCENOSULFONICO, LA CUAL A SU VEZ SE CONVIERTE INICIALMENTE EN LA DISAL DE PIPERACINA CORRESPONDIENTE QUE SE SEPARA EN MEDIO ACUOSO Y FINALMENTE EN MEDIO HIDROALCOHOLICO SE OBTIENE LA SAL DE PIPERACINA DEL MONOTOSILATO DEL ACIDO 2,5-DIHIDROXIBENCENOSULFONICO, TAMBIEN CONOCIDA COMO SULTOSILATO DE PIPERACINA. APLICACIONES MEDICINALES.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES8902754A ES2015433A6 (es) | 1989-08-03 | 1989-08-03 | Procedimientos de preparacion de la sal de piperacina del monotosilato del acido 2,5-dihidroxibencenosulfonico |
US07/557,918 US5082941A (en) | 1989-08-03 | 1990-07-25 | Process for preparing the piperazine salt of 2,5-dihydroxybenzenesulphonic acid monotosylate |
JP2201030A JPH0366662A (ja) | 1989-08-03 | 1990-07-27 | 2,5―ジヒドロキシベンゼンスルホン酸モノトシラートピペラジン塩の製造法 |
EP19900402205 EP0412011A3 (en) | 1989-08-03 | 1990-08-01 | Process for preparing the piperazine salt of 2,5-dihydroxybenzenesulphonic acid monotosylate |
CA002022618A CA2022618A1 (en) | 1989-08-03 | 1990-08-02 | Process for preparing the piperazine salt of 2,5-dihydroxybenzenesulphonic acid monotosylate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES8902754A ES2015433A6 (es) | 1989-08-03 | 1989-08-03 | Procedimientos de preparacion de la sal de piperacina del monotosilato del acido 2,5-dihidroxibencenosulfonico |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2015433A6 true ES2015433A6 (es) | 1990-08-16 |
Family
ID=8263440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8902754A Expired - Lifetime ES2015433A6 (es) | 1989-08-03 | 1989-08-03 | Procedimientos de preparacion de la sal de piperacina del monotosilato del acido 2,5-dihidroxibencenosulfonico |
Country Status (5)
Country | Link |
---|---|
US (1) | US5082941A (es) |
EP (1) | EP0412011A3 (es) |
JP (1) | JPH0366662A (es) |
CA (1) | CA2022618A1 (es) |
ES (1) | ES2015433A6 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2491226T3 (es) | 2006-08-16 | 2014-09-05 | AmDerma Pharmaceuticals, LLC | Compuestos de 2,5-dihidroxibenceno para el tratamiento de psoriaris |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH563356A5 (es) * | 1972-05-17 | 1975-06-30 | Esteve Dr Lab Del Sa | |
CH591437A5 (es) * | 1974-05-08 | 1977-09-15 | Esteve Dr Lab Del Sa | |
AR204506A1 (es) * | 1972-05-17 | 1976-02-12 | Esteve Labor Dr | Procedimiento de preparacion de sales de acidos p-dihidroxibencenodisulfonicos |
US3954767A (en) * | 1972-05-17 | 1976-05-04 | Esteve Subirana Antonio | Piperazine salts of 2,5-dihydroxy benzene sulfonic acid mono- and diesters |
ZA745083B (en) * | 1973-09-11 | 1975-08-27 | Esteve Labor Dr | Process for the preparation of monoesters and diesters of 2,5-dihydroxy-benzene-sulphonic acid |
US4115648A (en) * | 1974-09-13 | 1978-09-19 | Laboratorios Del Dr. Esteve, S.A. | 2,5-Dihydroxy benzene sulfonic acid mono esters |
IT8222600A0 (it) * | 1982-07-28 | 1982-07-28 | Pietro Tommaso Tessitore | Nuovi idrossibenzensolfonati della 5-(o-clorobenzil)-4,5,6,7-tetraidro tieno parentesi quadra aperta 3,2-c parentesi quadra chiusa piridina. |
-
1989
- 1989-08-03 ES ES8902754A patent/ES2015433A6/es not_active Expired - Lifetime
-
1990
- 1990-07-25 US US07/557,918 patent/US5082941A/en not_active Expired - Fee Related
- 1990-07-27 JP JP2201030A patent/JPH0366662A/ja active Pending
- 1990-08-01 EP EP19900402205 patent/EP0412011A3/en not_active Withdrawn
- 1990-08-02 CA CA002022618A patent/CA2022618A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US5082941A (en) | 1992-01-21 |
EP0412011A3 (en) | 1991-04-17 |
CA2022618A1 (en) | 1991-02-04 |
JPH0366662A (ja) | 1991-03-22 |
EP0412011A2 (en) | 1991-02-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20100412 |