ES2008151A6 - Procedimiento para la preparacion de un polipepido util para la obtencion de vacunas contra la malaria y para la deteccion de enfermedades paludicas - Google Patents
Procedimiento para la preparacion de un polipepido util para la obtencion de vacunas contra la malaria y para la deteccion de enfermedades paludicasInfo
- Publication number
- ES2008151A6 ES2008151A6 ES8702234A ES8702234A ES2008151A6 ES 2008151 A6 ES2008151 A6 ES 2008151A6 ES 8702234 A ES8702234 A ES 8702234A ES 8702234 A ES8702234 A ES 8702234A ES 2008151 A6 ES2008151 A6 ES 2008151A6
- Authority
- ES
- Spain
- Prior art keywords
- peptides
- diagnostic kits
- protein
- antimalarial vaccines
- region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 238000009007 Diagnostic Kit Methods 0.000 title 1
- 230000000078 anti-malarial effect Effects 0.000 title 1
- 239000003430 antimalarial agent Substances 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 235000018102 proteins Nutrition 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract 1
- 241000223960 Plasmodium falciparum Species 0.000 abstract 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 1
- 229960001230 asparagine Drugs 0.000 abstract 1
- 235000009582 asparagine Nutrition 0.000 abstract 1
- 230000003252 repetitive effect Effects 0.000 abstract 1
- 210000003046 sporozoite Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE UN POLIPEPTIDO CONSTITUIDO POR UN PEPTIDO DE SINTESIS QUE REPITE LA REGION 1 DE P. FALCIPARUM Y POR UN NUMERO VARIABLE DE UNIDADES DEL TETRAPEPTIDO REPETITIVAS DE LA PROTEINA CS DE P. FALCIPARUM VINCULADAS ENTRE SI MEDIANTE ENLACE AMIDICO ENTRE LA PROLINA TERMINAL DE LA REGION 1 Y LA ASPARAGINA INICIAL DEL PRIMER TETRAPEPTIDO, CONSISTENTE EN UN PROCESO DE SINTESIS EN FASE SOLIDA QUE COMPRENDE UNA SERIE DE CONDENSACIONES SUCESIVAS DE DIVERSOS AMINOACIDOS A UN SOPORTE SOLIDO INSOLUBLE MEDIANTE RESPECTIVAS REACCIONES DE ESTERIFICACION Y ACILACION, EL DESBLOQUEO DEL POLIPEPTIDO ASI OBTENIDO DEL SOPORTE SOLIDO INSOLUBLE MEDIANTE HIDROLISIS ACIDA, Y SU RECUPERACION Y PURIFICACION MEDIANTE CROMATOGRAFIA. DICHO POLIPEPTIDO ES UTIL PARA LA OBTENCION DE VACUNAS CONTRA LA MALARIA Y PARA LA DETECCION DE ENFERMEDADES PALUDICAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21144/86A IT1196501B (it) | 1986-07-16 | 1986-07-16 | Polipeptide utile per la preparazione di vaccini per la malaria e di kits diagnostici per la determinazione di affezioni malariche |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2008151A6 true ES2008151A6 (es) | 1989-07-16 |
Family
ID=11177390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8702234A Expired ES2008151A6 (es) | 1986-07-16 | 1987-07-14 | Procedimiento para la preparacion de un polipepido util para la obtencion de vacunas contra la malaria y para la deteccion de enfermedades paludicas |
Country Status (13)
| Country | Link |
|---|---|
| AT (1) | ATA179087A (es) |
| BE (1) | BE1000729A4 (es) |
| CH (1) | CH673461A5 (es) |
| DE (1) | DE3723583A1 (es) |
| ES (1) | ES2008151A6 (es) |
| FR (1) | FR2601590B1 (es) |
| GB (1) | GB2193215B (es) |
| GR (1) | GR871021B (es) |
| IT (1) | IT1196501B (es) |
| NL (1) | NL8701686A (es) |
| OA (1) | OA08626A (es) |
| SE (1) | SE468393B (es) |
| ZA (1) | ZA874778B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2055785T3 (es) * | 1989-01-17 | 1994-09-01 | Eniricerche Spa | Peptidos sinteticos y su uso como vehiculos universales para la preparacion de conjugados inmunogenos aptos para el desarrollo de vacunas sinteticas. |
| CA2031468A1 (en) * | 1989-12-08 | 1991-06-09 | Mitchell S. Gross | Malaria vaccine |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4707357A (en) * | 1984-06-26 | 1987-11-17 | The United States Of America As Represented By The Secretary Of The Army | Immunologically active peptides capable of inducing immunization against malaria and genes encoding therefor |
| PT82282B (pt) * | 1985-03-28 | 1988-02-17 | Univ New York | Processo de preparacao de um conjugado de proteina de suporte-antigeno imunogenico para uso como vacina contra malaria |
| IT1187710B (it) * | 1985-07-25 | 1987-12-23 | Eniricerche Spa | Composizione peptidica utile per la preparazione di vaccini per la malaria e di kit diagnostici per la determinazione di affezioni malariche |
-
1986
- 1986-07-16 IT IT21144/86A patent/IT1196501B/it active
-
1987
- 1987-06-30 SE SE8702698A patent/SE468393B/sv not_active IP Right Cessation
- 1987-06-30 GR GR871021A patent/GR871021B/el unknown
- 1987-07-01 ZA ZA874778A patent/ZA874778B/xx unknown
- 1987-07-02 CH CH2506/87A patent/CH673461A5/it not_active IP Right Cessation
- 1987-07-03 GB GB8715737A patent/GB2193215B/en not_active Expired - Lifetime
- 1987-07-03 OA OA59154A patent/OA08626A/xx unknown
- 1987-07-13 BE BE8700769A patent/BE1000729A4/fr not_active IP Right Cessation
- 1987-07-14 ES ES8702234A patent/ES2008151A6/es not_active Expired
- 1987-07-15 AT AT0179087A patent/ATA179087A/de not_active IP Right Cessation
- 1987-07-15 FR FR878709960A patent/FR2601590B1/fr not_active Expired - Lifetime
- 1987-07-16 DE DE19873723583 patent/DE3723583A1/de active Granted
- 1987-07-16 NL NL8701686A patent/NL8701686A/nl not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NL8701686A (nl) | 1988-02-16 |
| GB8715737D0 (en) | 1987-08-12 |
| GB2193215B (en) | 1990-03-07 |
| SE468393B (sv) | 1993-01-11 |
| FR2601590A1 (fr) | 1988-01-22 |
| CH673461A5 (es) | 1990-03-15 |
| ATA179087A (de) | 1996-07-15 |
| GR871021B (en) | 1987-11-13 |
| FR2601590B1 (fr) | 1990-05-18 |
| GB2193215A (en) | 1988-02-03 |
| SE8702698D0 (sv) | 1987-06-30 |
| BE1000729A4 (fr) | 1989-03-21 |
| DE3723583A1 (de) | 1988-01-28 |
| SE8702698L (sv) | 1988-01-17 |
| ZA874778B (en) | 1988-01-13 |
| IT8621144A0 (it) | 1986-07-16 |
| DE3723583C2 (es) | 1991-06-13 |
| OA08626A (en) | 1988-11-30 |
| IT1196501B (it) | 1988-11-16 |
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