ES2006730A6 - Un metodo de preparar un peptido o polipeptido sintetico que presenta la antigenicidad de la totalidad o una parte de un antigeno de p. falciparum - Google Patents

Un metodo de preparar un peptido o polipeptido sintetico que presenta la antigenicidad de la totalidad o una parte de un antigeno de p. falciparum

Info

Publication number
ES2006730A6
ES2006730A6 ES8603595A ES8603595A ES2006730A6 ES 2006730 A6 ES2006730 A6 ES 2006730A6 ES 8603595 A ES8603595 A ES 8603595A ES 8603595 A ES8603595 A ES 8603595A ES 2006730 A6 ES2006730 A6 ES 2006730A6
Authority
ES
Spain
Prior art keywords
falciparum
antigens
antigen
plasmodium falciparum
antigenicity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8603595A
Other languages
English (en)
Inventor
David James Kemp
Robin Fredric Anders
Ross Leon Coppel
Graham Vallance Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Walter and Eliza Hall Institute of Medical Research
Original Assignee
Walter and Eliza Hall Institute of Medical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Walter and Eliza Hall Institute of Medical Research filed Critical Walter and Eliza Hall Institute of Medical Research
Publication of ES2006730A6 publication Critical patent/ES2006730A6/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445Plasmodium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

UN METODO DE PREPARAR UN PEPTIDO O POLIPEPTIDO SINTETICO QUE PRESENTA LA ANTIGONICIDAD DE LA TOTALIDAD O UNA PARTE DE UN ANTIGENO DE P. FALCIPARUM, EN EL QUE SE CULTIVA UNA CELULA HOSPEDANTE QUE CONTIENE UNA MOLECULA DE ADN QUE COMPRENDE UNA SECUENCIA DE NUCLEOTIDOS CAPAZ DE SER EXPRESADA COMO AL MENOS UN POLIPEPTIDO CON LA ANTIGENICIDAD DE UN ANTIGENO DE P. FALCIPARUM, O UN VEHICULO O VECTOR DE CLONACION DE ADN RECOMBINANTE QUE TIENE INSERTADA UNA SECUENCIA DE NUCLEOTIDOS CAPAZ DE SER EXPRESADA COMO AL MENOS UN POLIPEPTIDO CON LA ANTIGENICIDAD DE UN ANTIGENO DE P. FALCIPARUM, Y SE RECUPERA DICHO PEPTIDO O POLIPEPTIDO DEL CULTIVO, COMPRENDIENDO AL MENOS UNA PORCION DE DICHA SECUENCIA DE NUCLEOTIDOS UNA SECUENCIA DE BASES QUE RESPONDE PREFERIBLEMENTE A LA FORMULA: LOS PRODUCTOS OBTENIDOS PUEDEN UTILIZARSE EN FORMULACIONES FARMACEUTICAS PARA ESTIMULAR RESPUESTAS INMUNES CONTRA ANTIGENOS DE P. FALCIPARUM EN MAMIFEROS.
ES8603595A 1985-12-24 1986-12-24 Un metodo de preparar un peptido o polipeptido sintetico que presenta la antigenicidad de la totalidad o una parte de un antigeno de p. falciparum Expired ES2006730A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPH402185 1985-12-24

Publications (1)

Publication Number Publication Date
ES2006730A6 true ES2006730A6 (es) 1989-05-16

Family

ID=3771425

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8603595A Expired ES2006730A6 (es) 1985-12-24 1986-12-24 Un metodo de preparar un peptido o polipeptido sintetico que presenta la antigenicidad de la totalidad o una parte de un antigeno de p. falciparum

Country Status (12)

Country Link
US (1) US5116755A (es)
EP (1) EP0252098A4 (es)
JP (1) JPS63502002A (es)
KR (1) KR880700812A (es)
DK (1) DK441287A (es)
ES (1) ES2006730A6 (es)
GR (1) GR862941B (es)
IL (1) IL81026A0 (es)
PT (1) PT84018B (es)
WO (1) WO1987003882A1 (es)
ZA (1) ZA869671B (es)
ZW (1) ZW25286A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286483A (en) * 1985-10-28 1994-02-15 Alain Vernes 50 kilodalton antigen obtained from the intraerythrocytic phase of plasmodium falciparum
WO1989010936A1 (en) * 1988-05-02 1989-11-16 The United States Of America, As Represented By Th Gene for encoding a human malaria vaccine antigen
US6333406B1 (en) 1988-08-12 2001-12-25 Joseph W. Inselburg Gene encoding protein antigens of Plasmodium falciparum and uses therefor
WO1990001549A2 (en) * 1988-08-12 1990-02-22 Trustees Of Dartmouth College Gene encoding protein antigens of plasmodium falciparum
GB8905857D0 (en) * 1989-03-14 1989-04-26 Hoffmann La Roche Plasmodium merozoite rhoptries antigen
WO1992002623A1 (en) * 1990-08-02 1992-02-20 Saramane Pty. Ltd. CLONING AND EXPRESSION OF A RHOPTRY ASSOCIATED PROTEIN OF $i(P.FALCIPARUM)
AU2003302240A1 (en) 2002-12-06 2004-06-30 Epimmune, Inc. Plasmodium falciparum antigens and methods of use
CN105561343B (zh) * 2016-02-04 2018-12-07 山东大学 一种预防人或动物弓形虫病的dna疫苗

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL65496A (en) * 1981-04-15 1985-10-31 Wellcome Found Protozoal antigen,its preparation and vaccine containing it
AU569722B2 (en) * 1983-01-28 1988-02-18 Saramane Pty Ltd Expression of plasmodium falciparum polypeptides from cloned cdna
DK79985A (da) * 1984-02-22 1985-08-23 Wellcome Found Kloning af dna for protozoelle antigener og dets anvendelse
IL76338A (en) * 1984-09-11 1994-08-26 Saramane Pty Ltd Plasmodium plasmodium immunogenic polypeptides, AND molecules encoding them, a method for preparing the polypeptides and preparations containing the polypeptide
IL78476A0 (en) * 1985-04-11 1986-08-31 Inst Medical W & E Hall Highly repetitive antigens of plasmodium falciparum

Also Published As

Publication number Publication date
ZA869671B (en) 1987-08-26
PT84018B (en) 1988-06-20
DK441287D0 (da) 1987-08-24
DK441287A (da) 1987-08-24
ZW25286A1 (en) 1987-04-01
PT84018A (en) 1987-01-01
KR880700812A (ko) 1988-04-12
GR862941B (en) 1987-04-28
WO1987003882A1 (en) 1987-07-02
JPS63502002A (ja) 1988-08-11
US5116755A (en) 1992-05-26
EP0252098A4 (en) 1989-11-29
EP0252098A1 (en) 1988-01-13
IL81026A0 (en) 1987-03-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010402