EP3823692A2 - Appareil et système d'insertion pour l'administration de médicament - Google Patents

Appareil et système d'insertion pour l'administration de médicament

Info

Publication number
EP3823692A2
EP3823692A2 EP19749511.2A EP19749511A EP3823692A2 EP 3823692 A2 EP3823692 A2 EP 3823692A2 EP 19749511 A EP19749511 A EP 19749511A EP 3823692 A2 EP3823692 A2 EP 3823692A2
Authority
EP
European Patent Office
Prior art keywords
reservoir
pump device
needle
secondary unit
body pump
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19749511.2A
Other languages
German (de)
English (en)
Inventor
Jason O'connor
Ian Mclaughlin
Daniel Allis
David Nazzaro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Insulet Corp
Original Assignee
Insulet Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insulet Corp filed Critical Insulet Corp
Publication of EP3823692A2 publication Critical patent/EP3823692A2/fr
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14566Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1407Infusion of two or more substances
    • A61M5/1408Infusion of two or more substances in parallel, e.g. manifolds, sequencing valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M5/1582Double lumen needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16877Adjusting flow; Devices for setting a flow rate
    • A61M5/16881Regulating valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3114Filling or refilling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3379Masses, volumes, levels of fluids in reservoirs, flow rates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00Ancillary equipment
    • A61M2209/04Tools for specific apparatus
    • A61M2209/045Tools for specific apparatus for filling, e.g. for filling reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1413Modular systems comprising interconnecting elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16877Adjusting flow; Devices for setting a flow rate

Definitions

  • the secondary unit 5 may include internal components (shown in other examples) for expelling a liquid drug from a liquid drug source, such as a prefilled cartridge 7, and delivering the liquid drug to a reservoir (shown in other examples) in the on-body pump device 14.
  • the prefilled cartridge 7 is shown inserted into an opening (shown in other examples) of the secondary unit 5.
  • the secondary unit 5 may be removed/decoupled from the on-body pump device 14.
  • the settings dial 6 of the secondary unit 5 may be operable to set or adjust operation of the on- body pump device (e.g., set or adjust dosages and/or flow rates of the liquid drug from the reservoir of the on-body pump device 14).
  • FIG. 3 illustrates a side view of an example of a drug delivery system 300.
  • the drug delivery system 300 includes an on-body pump device 301 and a secondary unit 305.
  • the needle insertion mechanism 325 may be configured to actuate the introducing needle device 321 of the on-body pump device 301.
  • the needle insertion mechanism 325 may include an insertion mechanism button 303, an insertion spring 304 and a member 333 coupled to the insertion spring 304.
  • the fill needle 309 may be coupled to a reservoir 310 (e.g., a bag reservoir) positioned in the on-body pump device 301. As the cartridge 307 is pushed into the secondary unit 305, the liquid drug (not shown) stored in the cartridge 307 may be expelled and delivered to the reservoir 310 through the fill needle 309.
  • a reservoir 310 e.g., a bag reservoir
  • FIG. 4 illustrates examples of components that may enable variably filling an on- body pump.
  • a user may set a required or desired fill volume using a dial, such as dial 6 of FIG. 1 or dial 306 of FIG. 3, on the secondary unit connected to a gear 27 operable to move a visual indicator 29 to the desired volume shown on a visual amount indicator component 25.
  • the visual amount indicator component 25 may include a volume scale (e.g., “units”) that shows a volume range of liquid drug that may be output by the variable fill mechanism 400.
  • the visual indicator 29 shows an amount on the visual amount indicator component 25 that has been output by the variable fill mechanism 400.
  • a needle 9 may be provided and is operable to pierce the movable plunger 20.
  • the indicator rod 24 may hit the hard stop 429 of the visual indicator 29 and prevent further fill.
  • a spring-loaded travel pin 22 releases the connection between the spring-loaded variable fill rod 21 and the indicator rod 24.
  • the spring-loaded variable fill rod 21 will return to its original position, ready for an additional cartridge to be inserted (if applicable). If the volume in the first cartridge is lower than the volume set by the user, a second cartridge may be inserted. Because the variable fill rod 21 may be spring-loaded, the variable fill rod 21 returns to its original position and the indicator rod 24 remains in place. Accordingly, the secondary unit 5 may be adjustable for any position of the plunger 20 within the cartridge 407.
  • the secondary unit 5 may include an energy storage system (e.g., a spring system) that may be used for aiding the filling process.
  • an energy storage system e.g., a spring system
  • the user may place the prefilled cartridge into the secondary unit and actuate a button or the like to trigger the energy storage system which pushes the prefilled cartridge into the opening.
  • Interlock device e.g., to require filling prior to allowing insertion

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

Selon des modes de réalisation donnés à titre d'exemple, l'invention concerne un système d'administration de médicament et des composants de celui-ci. Le système peut comprendre un dispositif de pompe sur corps et une unité secondaire. Le dispositif de pompe sur corps peut comprendre un réservoir et un trajet de fluide. Le réservoir peut être conçu pour contenir un médicament liquide. L'unité secondaire peut être accouplée amovible au dispositif de pompe sur corps. L'unité secondaire peut être conçue pour recevoir une cartouche pré-remplie contenant un médicament liquide, expulser le médicament liquide de la cartouche pré-remplie, et distribuer le médicament liquide au réservoir du dispositif de pompe sur corps par l'intermédiaire du trajet de fluide. Des exemples de variations de l'unité secondaire sont également décrits.
EP19749511.2A 2018-07-18 2019-07-18 Appareil et système d'insertion pour l'administration de médicament Pending EP3823692A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862699805P 2018-07-18 2018-07-18
PCT/US2019/042408 WO2020018792A2 (fr) 2018-07-18 2019-07-18 Appareil et système d'insertion pour l'administration de médicament

Publications (1)

Publication Number Publication Date
EP3823692A2 true EP3823692A2 (fr) 2021-05-26

Family

ID=67539610

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19749511.2A Pending EP3823692A2 (fr) 2018-07-18 2019-07-18 Appareil et système d'insertion pour l'administration de médicament

Country Status (7)

Country Link
US (1) US11992653B2 (fr)
EP (1) EP3823692A2 (fr)
JP (1) JP7204875B2 (fr)
CN (1) CN112423804B (fr)
AU (2) AU2019308285B2 (fr)
CA (2) CA3226051A1 (fr)
WO (1) WO2020018792A2 (fr)

Families Citing this family (6)

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EP1762259B1 (fr) 2005-09-12 2010-09-08 Unomedical A/S Inserteur pour un équipement d'infusion avec une première et deuxieme unités de ressort
WO2012123274A1 (fr) 2011-03-14 2012-09-20 Unomedical A/S Système d'insertion doté d'une protection pour son transport
CN113950341B (zh) 2019-05-20 2024-03-19 优诺医疗有限公司 可旋转的输注装置及其方法
CN114247009A (zh) * 2020-09-25 2022-03-29 群康生技股份有限公司 出针机构
FR3134726A1 (fr) * 2022-04-26 2023-10-27 Société Industrielle de Sonceboz S.A. Système d’activation pour dispositif d’administration de médicament transdermique
WO2024064318A2 (fr) * 2022-09-23 2024-03-28 Becton, Dickinson And Company Procédé pour assurer un remplissage de produit médicamenteux dans un dispositif d'administration de médicament porté sur le corps

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Also Published As

Publication number Publication date
US11992653B2 (en) 2024-05-28
US20200023123A1 (en) 2020-01-23
JP2022501084A (ja) 2022-01-06
AU2023201793A1 (en) 2023-04-27
WO2020018792A3 (fr) 2020-02-20
AU2019308285A1 (en) 2021-03-11
CN112423804A (zh) 2021-02-26
AU2019308285B2 (en) 2022-12-22
CA3226051A1 (fr) 2020-01-23
CA3105177C (fr) 2024-02-27
CA3105177A1 (fr) 2020-01-23
CN112423804B (zh) 2023-07-18
JP7204875B2 (ja) 2023-01-16
WO2020018792A2 (fr) 2020-01-23

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