EP3688449A4 - Dispositifs à nanoélectrodes et procédés de fabrication associés - Google Patents

Dispositifs à nanoélectrodes et procédés de fabrication associés Download PDF

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Publication number
EP3688449A4
EP3688449A4 EP18861291.5A EP18861291A EP3688449A4 EP 3688449 A4 EP3688449 A4 EP 3688449A4 EP 18861291 A EP18861291 A EP 18861291A EP 3688449 A4 EP3688449 A4 EP 3688449A4
Authority
EP
European Patent Office
Prior art keywords
nanoelectrode
fabrication
methods
devices
nanoelectrode devices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18861291.5A
Other languages
German (de)
English (en)
Other versions
EP3688449A1 (fr
Inventor
Kazusuke MIHARA
Hisao Kawasaki
Valentin V. DIMITROV
Toshihiko HONKURA
Mark F. Oldham
Eric S. Nordman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quantum Biosystems Inc
Original Assignee
Quantum Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quantum Biosystems Inc filed Critical Quantum Biosystems Inc
Publication of EP3688449A1 publication Critical patent/EP3688449A1/fr
Publication of EP3688449A4 publication Critical patent/EP3688449A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3276—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a hybridisation with immobilised receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6823—Release of bound markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3278—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction involving nanosized elements, e.g. nanogaps or nanoparticles

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nanotechnology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
EP18861291.5A 2017-09-27 2018-09-27 Dispositifs à nanoélectrodes et procédés de fabrication associés Withdrawn EP3688449A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762563859P 2017-09-27 2017-09-27
PCT/JP2018/036086 WO2019065904A1 (fr) 2017-09-27 2018-09-27 Dispositifs à nanoélectrodes et procédés de fabrication associés

Publications (2)

Publication Number Publication Date
EP3688449A1 EP3688449A1 (fr) 2020-08-05
EP3688449A4 true EP3688449A4 (fr) 2021-11-24

Family

ID=65901624

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18861291.5A Withdrawn EP3688449A4 (fr) 2017-09-27 2018-09-27 Dispositifs à nanoélectrodes et procédés de fabrication associés

Country Status (3)

Country Link
EP (1) EP3688449A4 (fr)
TW (1) TW201928340A (fr)
WO (1) WO2019065904A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011108540A1 (fr) 2010-03-03 2011-09-09 国立大学法人大阪大学 Procédé et dispositif d'identification de nucléotides, et procédé et dispositif pour déterminer la séquence nucléotidique de polynucléotides
CN106104274B (zh) 2013-09-18 2018-05-22 量子生物有限公司 生物分子测序装置、***和方法
JP2015077652A (ja) 2013-10-16 2015-04-23 クオンタムバイオシステムズ株式会社 ナノギャップ電極およびその製造方法
US10438811B1 (en) 2014-04-15 2019-10-08 Quantum Biosystems Inc. Methods for forming nano-gap electrodes for use in nanosensors
WO2015170782A1 (fr) 2014-05-08 2015-11-12 Osaka University Dispositifs, systèmes et procédés pour la linéarisation de polymères

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017189930A1 (fr) * 2016-04-27 2017-11-02 Quantum Biosystems Inc. Systèmes et procédés de mesure et de séquençage de biomolécules

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040248282A1 (en) * 2001-06-11 2004-12-09 Pisharody Sobha M. Electronic detection of biological molecules using thin layers
US9395352B2 (en) * 2007-04-06 2016-07-19 Arizona Board Of Regents On Behalf Of Arizona State University Devices and methods for target molecule characterization
US8652779B2 (en) * 2010-04-09 2014-02-18 Pacific Biosciences Of California, Inc. Nanopore sequencing using charge blockade labels
WO2013016486A1 (fr) * 2011-07-27 2013-01-31 The Board Of Trustees Of The University Of Illinois Capteurs à nanopore pour la caractérisation biomoléculaire
JP2013090576A (ja) * 2011-10-24 2013-05-16 Hitachi Ltd 核酸分析デバイス及びそれを用いた核酸分析装置
WO2013154999A2 (fr) * 2012-04-09 2013-10-17 The Trustees Of Columbia University In The City Of New York Procédé de préparation de nanopore, et utilisations de celui-ci
US9551697B2 (en) * 2013-10-17 2017-01-24 Genia Technologies, Inc. Non-faradaic, capacitively coupled measurement in a nanopore cell array
JP6516000B2 (ja) * 2014-05-08 2019-05-22 国立大学法人大阪大学 異種材料を含むナノギャップ電極
EP3315461B1 (fr) * 2015-06-23 2021-07-07 BGI Shenzhen Micro-électrode poreuse et procédé d'analyse de substances chimiques

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017189930A1 (fr) * 2016-04-27 2017-11-02 Quantum Biosystems Inc. Systèmes et procédés de mesure et de séquençage de biomolécules

Also Published As

Publication number Publication date
EP3688449A1 (fr) 2020-08-05
TW201928340A (zh) 2019-07-16
WO2019065904A1 (fr) 2019-04-04

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Inventor name: OLDHAM, MARK F.

Inventor name: HONKURA, TOSHIHIKO

Inventor name: DIMITROV, VALENTIN V.

Inventor name: MIHARA, KAZUSUKE

Inventor name: KAWASAKI, HISAO

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