EP3454989B1 - Support housing for sampling cones for a pipetting system - Google Patents

Support housing for sampling cones for a pipetting system Download PDF

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Publication number
EP3454989B1
EP3454989B1 EP17721739.5A EP17721739A EP3454989B1 EP 3454989 B1 EP3454989 B1 EP 3454989B1 EP 17721739 A EP17721739 A EP 17721739A EP 3454989 B1 EP3454989 B1 EP 3454989B1
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EP
European Patent Office
Prior art keywords
casing
mating
notch
stacking direction
members
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EP17721739.5A
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German (de)
French (fr)
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EP3454989A1 (en
Inventor
Philippe GOMES CAVACO
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Gilson SAS
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Gilson SAS
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Priority to PL17721739T priority Critical patent/PL3454989T3/en
Publication of EP3454989A1 publication Critical patent/EP3454989A1/en
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/54—Supports specially adapted for pipettes and burettes
    • B01L9/543—Supports specially adapted for pipettes and burettes for disposable pipette tips, e.g. racks or cassettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0858—Side walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells

Definitions

  • the invention relates to the field of sampling cone support boxes intended for pipetting systems such as robots, automats, or sampling pipettes. These boxes are conventionally called "racks”.
  • Such boxes are intended to carry sampling cones before they are fitted onto the pipetting system, for example on the tips of a pipetting robot or on the tips of a multichannel, manual or motorized.
  • the pitch between the housing orifices of the sampling cones is such that it coincides with the pitch of the tips of the pipetting system, to allow easy insertion of these tips into the cones.
  • the boxes fitted with cones are stacked on top of each other.
  • the hollowed-out housing is removed from the stack and gives way to a lower housing filled with other cones.
  • the stack of boxes is caused to be manipulated by the operator, so that it is usually preferable to provide coupling means between the boxes. bunk.
  • the transition from one housing to another by the operator is effected by actuating the coupling means to unlock them, and thus allow the extraction of one of the two housings.
  • the invention therefore aims to respond at least partially to the problem identified above, relating to the embodiments of the prior art.
  • each of the first and second opposite sides is equipped with a female coupling member as well as with a male coupling member arranged substantially symmetrically on either side of said median notional plane, the two female organs for coupling the first and second opposite flanks being arranged on the same side of the median notional plane and the two male members for coupling the first and second opposite flanks being arranged on the other side of the median fictional plane, and said male and female coupling members are designed so that when two identical support housings are stacked in the stacking direction with an upper housing and a lower housing both having their male members on the same side of the notional plane middle, the upper case adopts a posed position in which it is not retained by the lower case in the stacking direction, and also designed so that when the upper case and the lower case have their male coupling members respectively on either side of the notional plane middle, the upper housing adopts a retained position in which its two male coupling members cooperate respectively with the two female coupling members of the lower housing.
  • the invention proposes an original solution making it possible to keep the same and unique design of housings, while being able to arrange them in the posed position or in the retained position, depending on the intended use.
  • This feature makes it easier to manufacture the boxes and simplifies the management of the latter by users.
  • it is no longer necessary to identify the type of case manufactured, or to choose from two separate stacking paths. This advantageously results in a great simplification of the production operations, and this generates substantial gains in terms of production time and programming development, etc.
  • the invention furthermore presents at least any one of the following optional technical characteristics, taken individually or in combination.
  • Each male coupling member comprises a tab pivotally mounted on its associated flank by means of a pivot connection with an axis substantially orthogonal to the stacking direction, the tab having on either side of the pivot connection a gripping portion, as well as a hooking portion ending in a notch.
  • Said pivot connection is produced by two cords of material elastically deformable in torsion, the two cords of material being aligned with each other along the axis of the pivot connection.
  • the gripping portion projects upwards beyond its associated flank, and said notch is arranged substantially at a low end of this flank.
  • the female member has in the upper part a ramp allowing, during a relative displacement of the upper housing towards the lower housing in the direction stacking, to rotate its associated male member around said pivot link by displacement of the notch along the ramp, before automatic insertion of the notch in the female member after this notch has left said ramp.
  • said automatic insertion of the notch in the female coupling member is effected by pivoting of the male coupling member caused by a release of energy previously stored by the pivot link, during movement of the notch along the ramp.
  • this insertion can be carried out not automatically, but manually by pressing on the gripping portions of the legs, then by releasing them.
  • Each female coupling member is arranged substantially at a high end of its associated flank, near a junction with the support for sampling cones.
  • the support has 96 holes for housing the sampling cones.
  • a different number of orifices can be provided, without departing from the scope of the invention.
  • the subject of the invention is also an assembly comprising several identical housings such as that described above, said housings being stacked in the stacking direction, in the posed position or in the retained position.
  • the assembly preferably comprises a hollow bottom arranged at the base of the stack of boxes, said hollow bottom comprising female members for coupling with the lowest case in the stack.
  • an assembly 100 is shown according to a preferred embodiment of the invention, this assembly corresponding to a stack of boxes for supporting sampling cones, for pipetting system.
  • the boxes 1 are superimposed in a stacking direction 2, corresponding here to the vertical direction. According to a specific feature of the invention which will be detailed below, the boxes 1 of the stack can either be simply placed one on top of the other, or retained to each other in the direction of stacking 2.
  • the boxes 1 are intended to contain sampling cones (not shown), also called consumables.
  • sampling cones also called consumables.
  • the figures 2 to 4 illustrate one of the boxes 1 of the stack, which all have an identical design.
  • the housing 1, made in one piece, has an overall parallelepiped shape, hollow and comprising an upper partition which fulfills a support function for consumables.
  • This support 10 is arranged in a plane orthogonal to the stacking direction 1, and equipped with orifices 12 for housing the sampling cones.
  • it is for example 96 orifices 12 distributed in rows and columns, in the manner of a matrix.
  • the pitch between the orifices 12 is provided to coincide with the pitch of the tips of the pipetting system, to allow easy insertion of these tips in the cones.
  • the housing 1 extends in length in a longitudinal direction 6 and in width in a transverse direction 8, the three directions 2, 6, 8 being orthogonal to each other.
  • the housing 1 comprises four flanks, including a first and a second opposite flanks 14a, 14b, integral with the support 10 and crossed by a median imaginary plane P integrating the stacking direction 2. Consequently, each of these two flanks 14a, 14b opposite in direction 6 extends in a transverse plane, defined by the two directions 2 and 8. Two other flanks 16a, 16b opposite in direction 8 complete the contour of the support 10, each extending in a longitudinal plane defined by the two directions 2 and 6.
  • One of the features of the invention resides in the design of coupling means between the successive housings, these means being able to be active or passive depending on the relative orientation of the housings in the stack, as will be explained below. after.
  • Each of the first and second opposite sides 14a, 14b is equipped with a female coupling member 18, in the form of a single slot opening outwards in the direction 6.
  • the female member 18 is arranged substantially at the level d 'an upper end of the sidewall on which it is located, near a junction with the support 10.
  • the slot is delimited in the upper part by a ramp 19 which extends outwards in direction 6, going towards the bottom.
  • Each of the first and second opposite flanks 14a, 14b is also equipped with a male coupling member 20, taking the form of a lug pivotally mounted on its associated flank, by means of a pivot connection 22.
  • the connection pivot 22 has a pivot axis 23 substantially orthogonal to the stacking direction 2, and parallel to the transverse direction 8. It is produced by two cords of material 26 elastically deformable in torsion along the axis 23, and aligned one with the other along this same axis.
  • the tab 20 has a height greater than that of the housing 1.
  • the notch 34 projects in the direction of the interior of the housing 1, in the direction 6 as opposed to the tab 20 which extends generally in the stacking direction 2.
  • each flank 14a, 14b the female member 18 and the male member 20 are arranged substantially symmetrically on either side of the fictitious median plane P.
  • the two female coupling members 18 of the first and second flanks opposite 14a, 14b are arranged on the same side of the median fictitious plane P, and the two male coupling members 20 of these same flanks are arranged on the other side of the median fictitious plane P.
  • the upper housing 1 adopts a position placed on the lower housing, without being retained in the stacking direction 2.
  • the male members 20 of the two housings are on the same side of the median notional plane P, and therefore overlap two by two in direction 6, as is also visible on the figure 5a .
  • This type of stacking in which the boxes 1 adopt the same angular position relative to a central stacking axis, is preferably retained in the case of the use of the assembly 100 by robots / automats, allowing the realization automated pipetting operations.
  • the upper housing 1 adopts a retained position relative to the lower housing 1, the retention being effected using the aforementioned coupling means.
  • the two housings 1 instead of adopting the same angular position, have an angular position offset by 180 ° relative to each other in relation to the central stacking axis, which leads the organs male of the two housings to be located respectively on either side of the median notional plane P. This thus allows the upper housing 1 to have its two male members 20 cooperating respectively with the two female members 18 of the lower housing, as is also shown on the figure 6a at the sides 14a.
  • This type of stack is preferably retained in the case of manual pipetting operations, with a sampling pipette. This allows the operator to move the stack of boxes 1 without risking to accidentally separate them from each other.
  • FIGS 7a to 7c illustrate a way of automatically assembling two boxes 1 one on the other, simply by moving them one towards the other in the stacking direction 2. They are first aligned in the direction 2 as shown on the figure 7a , until the notch 34 abuts against the ramp 19 of the female member 18, as shown on the figure 7b .
  • the continuation of the relative displacement carried out for example by simple pressure on the upper casing downwards, causes the notch 34 to move along the ramp 19 provided for this purpose.
  • the purpose of this ramp 19 is to spread the attachment portion 32 outward, in the direction 6, as illustrated in the figure 7c . This is possible thanks to the pivoting of the tab 20 around the connection 22, along the pivot axis 23.
  • the two beads of material forming the pivot connection 22 elastically deform in torsion along the axis 23. Therefore, when the pressure down brings the notch 34 opposite. the slot defined by the female member 18, at the outlet of the ramp 19, this notch 34 is inserted automatically into the female member 18 thanks to the release of energy previously stored by the pivot link. The retained position is then obtained, this being also known as the clipped position.
  • the two housings 1 can be coupled by exerting pressure on the gripping portions 30 so as to bring them inward, then releasing this pressure after having brought the notches opposite the female organs.
  • the same pressure 40 shown diagrammatically on the figure 8 can be exerted on the gripping portions 30, in order to remove the notches outside the female organs.
  • the upper housing can be extracted upwards, or the lower housing can be extracted downwards, so as to unstack.
  • FIGS 9 to 11 illustrate the fact that the upper edge of the hollow bottom 4 has female coupling members 18 'identical or similar to those housings 1, so as to be able to cooperate with the male members 20 of the lowest housing 1 in the stack.
  • a ramp system 19 ′ allows the automatic insertion of the notches of the organs 20 into the female organs 18 ′.

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Stackable Containers (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Devices For Use In Laboratory Experiments (AREA)

Description

DOMAINE TECHNIQUETECHNICAL AREA

L'invention se rapporte au domaine des boîtiers de support de cônes de prélèvement destinés aux systèmes de pipetage tels que des robots, automates, ou pipettes de prélèvement. Ces boîtiers sont conventionnellement dénommés « racks ».The invention relates to the field of sampling cone support boxes intended for pipetting systems such as robots, automats, or sampling pipettes. These boxes are conventionally called "racks".

ETAT DE LA TECHNIQUE ANTERIEURESTATE OF THE PRIOR ART

De tels boîtiers sont destinés à porter des cônes de prélèvement avant que ceux-ci soient emmanchés sur le système de pipetage, par exemple sur les embouts d'un robot de pipetage ou encore sur les embouts d'une pipette de prélèvement multicanal, manuelle ou motorisée. Le pas entre les orifices de logement des cônes de prélèvement est tel qu'il coïncide avec le pas des embouts du système de pipetage, pour permettre une insertion aisée de ces embouts dans les cônes.Such boxes are intended to carry sampling cones before they are fitted onto the pipetting system, for example on the tips of a pipetting robot or on the tips of a multichannel, manual or motorized. The pitch between the housing orifices of the sampling cones is such that it coincides with the pitch of the tips of the pipetting system, to allow easy insertion of these tips into the cones.

Habituellement, les boîtiers équipés de cônes sont empilés les uns sur les autres. Ainsi, lorsqu'un boîtier a été entièrement vidé de ses cônes suite à des actions répétées de pipetage, le boîtier évidé est retiré de l'empilement et laisse place à un boîtier inférieur rempli par d'autres cônes.Usually, the boxes fitted with cones are stacked on top of each other. Thus, when a housing has been completely emptied of its cones following repeated pipetting actions, the hollowed-out housing is removed from the stack and gives way to a lower housing filled with other cones.

Dans le cas d'opérations manuelles réalisées à l'aide de pipettes de prélèvement, l'empilement de boîtiers est amené à être manipulé par l'opérateur, de sorte qu'il est habituellement préférable de prévoir des moyens d'accouplement entre les boîtiers superposés. Dans ce cas, le passage d'un boîtier à un autre par l'opérateur s'effectue en actionnant les moyens d'accouplement pour les déverrouiller, et permettre ainsi l'extraction de l'un des deux boîtiers.In the case of manual operations carried out using sampling pipettes, the stack of boxes is caused to be manipulated by the operator, so that it is usually preferable to provide coupling means between the boxes. bunk. In this case, the transition from one housing to another by the operator is effected by actuating the coupling means to unlock them, and thus allow the extraction of one of the two housings.

Pour les opérations automatisées de pipetage à l'aide d'un robot ou d'un automate, ces moyens d'accouplement sont sources de complexification du procédé de pipetage, c'est la raison pour laquelle les boîtiers sont généralement simplement posés les uns sur les autre dans l'empilement, sans moyens de retenue entre eux.For automated pipetting operations using a robot or an automaton, these coupling means are a source of complexity of the pipetting process, this is the reason why the boxes are generally simply placed one on the other. the others in the stack, without retaining means between them.

Quelques exemples de boîtiers de support de cônes de prélèvement empilables déjà existants sont donnés dans les documents suivants: US 2016/0101422 , US 2012/0257953 , US 2006/0045815 et DE 92 16 674 .Some examples of already existing stackable sampling cone support boxes are given in the following documents: US 2016/0101422 , US 2012/0257953 , US 2006/0045815 and DE 92 16 674 .

Cependant, la situation décrite ci-dessus conduit à fabriquer des boîtiers de conceptions différentes selon qu'ils sont destinés à une utilisation manuelle au automatisée. Cela complexifie le procédé de production des piles de boîtiers, car après fabrication de ces derniers, un robot agrippe chaque boîtier puis l'identifie afin de déterminer s'il doit être orienté vers une pile de boîtiers retenus les uns aux autres, ou bien vers une pile de boîtiers simplement posés les uns au-dessus des autres.However, the situation described above leads to the manufacture of boxes of different designs depending on whether they are intended for manual to automated use. This complicates the production process of the stacks of cases, because after manufacture of these, a robot grips each case and then identifies it in order to determine whether it should be oriented towards a stack of cases held together, or else towards a stack of boxes simply placed one above the other.

Du point de vue de l'utilisateur, un inconvénient analogue subsiste car il doit disposer des boîtiers de différents types, en fonction du système de pipetage mis en œuvre. Cela complexifie la gestion de ces supports de consommables.From the user's point of view, a similar drawback remains because it must have housings of different types, depending on the pipetting system used. This complicates the management of these consumables supports.

EXPOSÉ DE L'INVENTIONSTATEMENT OF THE INVENTION

L'invention a donc pour but de répondre au moins partiellement à la problématique identifiée ci-dessus, relative aux réalisations de l'art antérieur.The invention therefore aims to respond at least partially to the problem identified above, relating to the embodiments of the prior art.

Pour ce faire, l'invention a pour objet un boîtier de support de cônes de prélèvement pour système de pipetage, le boîtier étant destiné à être empilé avec d'autres boîtiers identiques selon une direction d'empilement, et comprenant :

  • un support pourvu d'orifices pour le logement des cônes de prélèvement ; et
  • un premier et un second flancs opposés solidaires du support et traversés par un plan fictif médian intégrant la direction d'empilement.
To do this, the subject of the invention is a housing for the support of sampling cones for a pipetting system, the housing being intended to be stacked with other identical housings in a stacking direction, and comprising:
  • a support provided with orifices for housing the sampling cones; and
  • first and second opposite flanks integral with the support and crossed by a fictitious median plane integrating the stacking direction.

Selon l'invention, chacun des premier et second flancs opposés est équipé d'un organe femelle d'accouplement ainsi que d'un organe mâle d'accouplement agencés sensiblement symétriquement de part et d'autre dudit plan fictif médian, les deux organes femelles d'accouplement des premier et second flancs opposés étant agencés d'un même côté du plan fictif médian et les deux organes mâles d'accouplement des premier et second flancs opposés étant agencés de l'autre côté du plan fictif médian,
et lesdits organes mâles et femelles d'accouplement sont conçus de sorte que lorsque deux boîtiers de support identiques sont empilés selon la direction d'empilement avec un boîtier supérieur et un boîtier inférieur présentant tous deux leurs organes mâles d'un même côté du plan fictif médian, le boîtier supérieur adopte une position posée dans laquelle il est non retenu par le boîtier inférieur dans la direction d'empilement, et également conçus de sorte que lorsque le boîtier supérieur et le boîtier inférieur présentent leurs organes mâles d'accouplement respectivement de part et d'autre du plan fictif médian, le boîtier supérieur adopte une position retenue dans laquelle ses deux organes mâles d'accouplement coopèrent respectivement avec les deux organes femelles d'accouplement du boîtier inférieur.According to the invention, each of the first and second opposite sides is equipped with a female coupling member as well as with a male coupling member arranged substantially symmetrically on either side of said median notional plane, the two female organs for coupling the first and second opposite flanks being arranged on the same side of the median notional plane and the two male members for coupling the first and second opposite flanks being arranged on the other side of the median fictional plane,
and said male and female coupling members are designed so that when two identical support housings are stacked in the stacking direction with an upper housing and a lower housing both having their male members on the same side of the notional plane middle, the upper case adopts a posed position in which it is not retained by the lower case in the stacking direction, and also designed so that when the upper case and the lower case have their male coupling members respectively on either side of the notional plane middle, the upper housing adopts a retained position in which its two male coupling members cooperate respectively with the two female coupling members of the lower housing.

Ainsi, l'invention propose une solution originale permettant de conserver une même et unique conception de boîtiers, tout en pouvant les disposer en position posée ou en position retenue, en fonction de l'utilisation envisagée. Cette particularité permet de faciliter la fabrication des boîtiers et simplifie la gestion de ces derniers par les utilisateurs. Notamment, dans la chaîne de production des boîtiers, il n'est plus nécessaire d'identifier le type de boîtier fabriqué, ni de choisir parmi deux voies distinctes d'empilement. Il en découle avantageusement une grande simplification des opérations de production, et cela génère des gains substantiels en termes de temps de production et de développement de programmation, etc.Thus, the invention proposes an original solution making it possible to keep the same and unique design of housings, while being able to arrange them in the posed position or in the retained position, depending on the intended use. This feature makes it easier to manufacture the boxes and simplifies the management of the latter by users. In particular, in the case production chain, it is no longer necessary to identify the type of case manufactured, or to choose from two separate stacking paths. This advantageously results in a great simplification of the production operations, and this generates substantial gains in terms of production time and programming development, etc.

L'invention présente par ailleurs au moins l'une quelconque des caractéristiques techniques optionnelles suivantes, prises isolément ou en combinaison.The invention furthermore presents at least any one of the following optional technical characteristics, taken individually or in combination.

Chaque organe mâle d'accouplement comprend une patte montée pivotante sur son flanc associé par l'intermédiaire d'une liaison pivot d'axe sensiblement orthogonal à la direction d'empilement, la patte présentant de part et d'autre de la liaison pivot une portion de préhension, ainsi qu'une portion d'accrochage se terminant par un cran.Each male coupling member comprises a tab pivotally mounted on its associated flank by means of a pivot connection with an axis substantially orthogonal to the stacking direction, the tab having on either side of the pivot connection a gripping portion, as well as a hooking portion ending in a notch.

Ladite liaison pivot est réalisée par deux cordons de matière déformables élastiquement en torsion, les deux cordons de matière étant alignés l'un avec l'autre selon l'axe de la liaison pivot.Said pivot connection is produced by two cords of material elastically deformable in torsion, the two cords of material being aligned with each other along the axis of the pivot connection.

La portion de préhension fait saillie vers le haut au-delà de son flanc associé, et ledit cran se trouve agencé sensiblement au niveau d'une extrémité basse de ce flanc.The gripping portion projects upwards beyond its associated flank, and said notch is arranged substantially at a low end of this flank.

L'organe femelle présente en partie supérieure une rampe permettant, lors d'un déplacement relatif du boîtier supérieur vers le boîtier inférieur dans la direction d'empilement, de faire pivoter son organe mâle associé autour de ladite liaison pivot par déplacement du cran le long de la rampe, avant insertion automatique du cran dans l'organe femelle après que ce cran ait quitté ladite rampe.The female member has in the upper part a ramp allowing, during a relative displacement of the upper housing towards the lower housing in the direction stacking, to rotate its associated male member around said pivot link by displacement of the notch along the ramp, before automatic insertion of the notch in the female member after this notch has left said ramp.

Dans ce cas de figure, ladite insertion automatique du cran dans l'organe femelle d'accouplement s'effectue par pivotement de l'organe mâle d'accouplement provoqué par une libération d'énergie préalablement emmagasinée par la liaison pivot, lors du déplacement du cran le long de la rampe.In this case, said automatic insertion of the notch in the female coupling member is effected by pivoting of the male coupling member caused by a release of energy previously stored by the pivot link, during movement of the notch along the ramp.

Alternativement, cette insertion peut s'effectuer non pas automatiquement, mais manuellement en appuyant sur les portions de préhension des pattes, puis en les relâchant.Alternatively, this insertion can be carried out not automatically, but manually by pressing on the gripping portions of the legs, then by releasing them.

Chaque organe femelle d'accouplement se trouve agencé sensiblement au niveau d'une extrémité haute de son flanc associé, à proximité d'une jonction avec le support de cônes de prélèvement.Each female coupling member is arranged substantially at a high end of its associated flank, near a junction with the support for sampling cones.

Le support présente 96 orifices pour le logement des cônes de prélèvement. Bien entendu, il peut être prévu un nombre différent d'orifices, sans sortir du cadre de l'invention.The support has 96 holes for housing the sampling cones. Of course, a different number of orifices can be provided, without departing from the scope of the invention.

L'invention a également pour objet un ensemble comprenant plusieurs boîtiers identiques tel que celui décrit ci-dessus, lesdits boîtiers étant empilés selon la direction d'empilement, dans la position posée ou dans la position retenue.The subject of the invention is also an assembly comprising several identical housings such as that described above, said housings being stacked in the stacking direction, in the posed position or in the retained position.

Enfin, l'ensemble comprend de préférence un fond creux agencé à la base de l'empilement de boîtiers, ledit fond creux comprenant des organes femelles d'accouplement avec le boîtier le plus bas dans l'empilement.Finally, the assembly preferably comprises a hollow bottom arranged at the base of the stack of boxes, said hollow bottom comprising female members for coupling with the lowest case in the stack.

D'autres avantages et caractéristiques de l'invention apparaîtront dans la description détaillée non limitative ci-dessous.Other advantages and characteristics of the invention will appear in the detailed non-limiting description below.

BRÈVE DESCRIPTION DES DESSINSBRIEF DESCRIPTION OF THE DRAWINGS

Cette description sera faite au regard des dessins annexés parmi lesquels ;

  • la figure 1 représente une vue de face, partiellement en coupe, d'un ensemble empilé de boîtiers de support de cônes de prélèvement, selon un mode de réalisation préféré de l'invention ;
  • la figure 2 représente une vue en perspective de l'un des boîtiers de l'empilement montré sur la figure précédente ;
  • la figure 3 est une vue en coupe longitudinale d'une partie du boîtier montré sur la figure précédente, passant par l'un de ses organes mâles d'accouplement ;
  • la figure 4 est une vue de dessus du boîtier montré sur les figures 2 et 3;
  • la figure 5 est une vue en perspective d'un empilement de deux boîtiers en position posée ;
  • la figure 6 est une vue en perspective d'un empilement de deux boîtiers en position retenue ;
  • la figure 5a est une vue en coupe longitudinale d'une partie de l'empilement montré sur la figure 5, passant par les organes mâles d'accouplement ;
  • la figure 6a est une vue en coupe longitudinale d'une partie de l'empilement montré sur la figure 6, passant par les organes mâle et femelle d'accouplement ;
  • les figures 7a à 7c illustrent différentes étapes d'assemblage des boîtiers de l'empilement montré sur les figures 6 et 6a ;
  • la figure 8 illustrent une manière de désaccoupler les deux boîtiers montrés sur les figures 6, 6a et 7a à 7c ;
  • la figure 9 est une vue en perspective d'un fond creux coopérant avec le boîtier le plus bas dans l'empilement ;
  • la figure 10 est une vue similaire à celle de la figure 9, sans le boîtier; et
  • la figure 11 est une vue en coupe transversale prise sur la figure 9, et passant par l'organe mâle d'accouplement du boîtier.
This description will be made with reference to the accompanying drawings, among which;
  • the figure 1 shows a front view, partially in section, of a stacked set of sampling cone support boxes, according to a preferred embodiment of the invention;
  • the figure 2 shows a perspective view of one of the boxes of the stack shown in the previous figure;
  • the figure 3 is a view in longitudinal section of a part of the housing shown in the previous figure, passing through one of its male coupling members;
  • the figure 4 is a top view of the housing shown on the figures 2 and 3 ;
  • the figure 5 is a perspective view of a stack of two boxes in the posed position;
  • the figure 6 is a perspective view of a stack of two housings in the retained position;
  • the figure 5a is a longitudinal section view of part of the stack shown on the figure 5 , passing through the male coupling members;
  • the figure 6a is a longitudinal section view of part of the stack shown on the figure 6 , passing through the male and female coupling members;
  • the Figures 7a to 7c illustrate different stages of assembling the boxes of the stack shown on the Figures 6 and 6a ;
  • the figure 8 illustrate a way of uncoupling the two boxes shown on the Figures 6, 6a and 7a to 7c ;
  • the figure 9 is a perspective view of a hollow bottom cooperating with the lowest case in the stack;
  • the figure 10 is a view similar to that of the figure 9 , without the housing; and
  • the figure 11 is a cross-sectional view taken on the figure 9 , and passing through the male coupling member of the housing.

EXPOSÉ DÉTAILLÉ DE MODES DE RÉALISATION PRÉFÉRÉSDETAILED DESCRIPTION OF PREFERRED EMBODIMENTS

En référence à la figure 1, il est représenté un ensemble 100 selon un mode de réalisation préféré de l'invention, cet ensemble correspondant à un empilement de boîtiers de support de cônes de prélèvement, pour système de pipetage.With reference to the figure 1 , an assembly 100 is shown according to a preferred embodiment of the invention, this assembly corresponding to a stack of boxes for supporting sampling cones, for pipetting system.

Les boîtiers 1 sont superposés selon une direction d'empilement 2, correspondant ici à la direction verticale. Selon une spécificité de l'invention qui sera détaillée ci-après, les boîtiers 1 de l'empilement peuvent être soit simplement posés les uns sur les autres, soit retenus les uns aux autres selon la direction d'empilement 2.The boxes 1 are superimposed in a stacking direction 2, corresponding here to the vertical direction. According to a specific feature of the invention which will be detailed below, the boxes 1 of the stack can either be simply placed one on top of the other, or retained to each other in the direction of stacking 2.

Les boîtiers 1 sont destinés à contenir des cônes de prélèvement (non représentés), également dénommés consommables. Ainsi, lorsque l'ensemble des cônes sont retirés du boîtier le plus haut de l'empilement, ce même boîtier est extrait de l'empilement et donne accès aux cônes portés par le boîtier directement consécutifs. Ce processus est réitéré jusqu'au boîtier le plus bas, porté par un fond creux 4 agencé à la base de l'empilement.The boxes 1 are intended to contain sampling cones (not shown), also called consumables. Thus, when all of the cones are removed from the uppermost housing of the stack, this same housing is extracted from the stack and gives access to the cones carried by the housing directly consecutive. This process is repeated up to the lowest case, carried by a hollow bottom 4 arranged at the base of the stack.

Les figures 2 à 4 illustrent l'un des boîtiers 1 de l'empilement, qui présentent tous une conception identique.The figures 2 to 4 illustrate one of the boxes 1 of the stack, which all have an identical design.

Le boîtier 1, réalisé d'une seule pièce, dispose d'un forme globale parallélépipédique, creuse et comprenant une cloison supérieure qui remplit une fonction de support pour les consommables. Ce support 10 est agencé dans un plan orthogonal à la direction d'empilement 1, et équipé d'orifices 12 pour le logement des cônes de prélèvement. Ici, il s'agit par exemple de 96 orifices 12 répartis en rangées et colonnes, à la manière d'une matrice. Le pas entre les orifices 12 est prévu pour coïncider avec le pas des embouts du système de pipetage, pour permettre une insertion aisée de ces embouts dans les cônes.The housing 1, made in one piece, has an overall parallelepiped shape, hollow and comprising an upper partition which fulfills a support function for consumables. This support 10 is arranged in a plane orthogonal to the stacking direction 1, and equipped with orifices 12 for housing the sampling cones. Here, it is for example 96 orifices 12 distributed in rows and columns, in the manner of a matrix. The pitch between the orifices 12 is provided to coincide with the pitch of the tips of the pipetting system, to allow easy insertion of these tips in the cones.

Le boîtier 1 s'étend en longueur selon une direction longitudinale 6 et en largeur selon une direction transversale 8, les trois directions 2, 6, 8 étant orthogonales entre elles.The housing 1 extends in length in a longitudinal direction 6 and in width in a transverse direction 8, the three directions 2, 6, 8 being orthogonal to each other.

A la périphérie du support 10, le boîtier 1 comprend des quatre flancs, dont un premier et un second flancs opposés 14a, 14b, solidaires du support 10 et traversés par un plan fictif médian P intégrant la direction d'empilement 2. Par conséquent, chacun de ces deux flancs 14a, 14b opposés selon la direction 6 s'étend dans un plan transversal, défini par les deux directions 2 et 8. Deux autres flancs 16a, 16b opposés selon la direction 8 complètent le contour du support 10, en s'étendant chacun dans un plan longitudinal défini par les deux directions 2 et 6.At the periphery of the support 10, the housing 1 comprises four flanks, including a first and a second opposite flanks 14a, 14b, integral with the support 10 and crossed by a median imaginary plane P integrating the stacking direction 2. Consequently, each of these two flanks 14a, 14b opposite in direction 6 extends in a transverse plane, defined by the two directions 2 and 8. Two other flanks 16a, 16b opposite in direction 8 complete the contour of the support 10, each extending in a longitudinal plane defined by the two directions 2 and 6.

L'une des particularités de l'invention réside dans la conception de moyens d'accouplement entre les boîtiers successifs, ces moyens pouvant être actifs ou passifs en fonction du l'orientation relative des boîtiers dans l'empilement, comme cela sera expliqué ci-après.One of the features of the invention resides in the design of coupling means between the successive housings, these means being able to be active or passive depending on the relative orientation of the housings in the stack, as will be explained below. after.

Chacun des premier et second flancs opposés 14a, 14b est équipé d'un organe femelle d'accouplement 18, en forme de simple fente s'ouvrant vers l'extérieur dans la direction 6. L'organe femelle 18 est agencé sensiblement au niveau d'une extrémité haute du flanc sur lequel elle se trouve, à proximité d'une jonction avec le support 10. La fente est délimitée en partie supérieure par une rampe 19 qui s'étend vers l'extérieur dans la direction 6, en allant vers le bas.Each of the first and second opposite sides 14a, 14b is equipped with a female coupling member 18, in the form of a single slot opening outwards in the direction 6. The female member 18 is arranged substantially at the level d 'an upper end of the sidewall on which it is located, near a junction with the support 10. The slot is delimited in the upper part by a ramp 19 which extends outwards in direction 6, going towards the bottom.

Chacun des premier et second flancs opposés 14a, 14b est aussi équipé d'un organe mâle d'accouplement 20, prenant la forme d'une patte montée pivotante sur son flanc associé, par l'intermédiaire d'une liaison pivot 22. La liaison pivot 22 présente un axe de pivotement 23 sensiblement orthogonal à la direction d'empilement 2, et parallèle à la direction transversale 8. Elle est réalisée par deux cordons de matière 26 déformables élastiquement en torsion selon l'axe 23, et alignés l'un avec l'autre selon ce même axe.Each of the first and second opposite flanks 14a, 14b is also equipped with a male coupling member 20, taking the form of a lug pivotally mounted on its associated flank, by means of a pivot connection 22. The connection pivot 22 has a pivot axis 23 substantially orthogonal to the stacking direction 2, and parallel to the transverse direction 8. It is produced by two cords of material 26 elastically deformable in torsion along the axis 23, and aligned one with the other along this same axis.

La patte 20 présente une hauteur supérieure à celle du boîtier 1. De part et d'autre de la liaison pivot 22, elle comprend d'une part une portion de préhension 30 s'étendant vers le haut en faisant saillie au-delà de son flanc associé et du support 10, et d'autre part une portion d'accrochage 32 se terminant par un cran 34 agencé sensiblement au niveau d'une extrémité basse du flanc.The tab 20 has a height greater than that of the housing 1. On either side of the pivot link 22, it comprises on the one hand a gripping portion 30 extending upwardly projecting beyond its associated sidewall and support 10, and secondly a hooking portion 32 ending in a notch 34 arranged substantially at a lower end of the sidewall.

Le cran 34 se projette en direction de l'intérieur du boîtier 1, selon la direction 6 par opposition à la patte 20 qui s'étend globalement dans la direction d'empilement 2.The notch 34 projects in the direction of the interior of the housing 1, in the direction 6 as opposed to the tab 20 which extends generally in the stacking direction 2.

Comme cela est le mieux visible sur la figure 4, sur chaque flanc 14a, 14b, l'organe femelle 18 et l'organe mâle 20 sont agencés sensiblement symétriquement de part et d'autre plan fictif médian P. De plus, les deux organes femelles d'accouplement 18 des premier et second flancs opposés 14a, 14b sont agencés d'un même côté du plan fictif médian P, et les deux organes mâles d'accouplement 20 de ces mêmes flancs sont agencés de l'autre côté du plan fictif médian P.As is best seen on the figure 4 , on each flank 14a, 14b, the female member 18 and the male member 20 are arranged substantially symmetrically on either side of the fictitious median plane P. In addition, the two female coupling members 18 of the first and second flanks opposite 14a, 14b are arranged on the same side of the median fictitious plane P, and the two male coupling members 20 of these same flanks are arranged on the other side of the median fictitious plane P.

De cette manière, il est possible d'empiler deux boîtiers 1 de deux manières différentes, représentées sur les figures 5 et 6. Dans l'empilement de la figure 5, le boîtier supérieur 1 adopte une position posée sur le boîtier inférieur, sans être retenu selon la direction d'empilement 2. En effet, dans ce cas de figure, les organes mâles 20 des deux boîtiers se trouvent du même côté du plan fictif médian P, et se recouvrent donc deux à deux selon la direction 6, comme cela est également visible sur la figure 5a.In this way, it is possible to stack two boxes 1 in two different ways, shown on the figures 5 and 6 . In the stack of figure 5 , the upper housing 1 adopts a position placed on the lower housing, without being retained in the stacking direction 2. Indeed, in this case, the male members 20 of the two housings are on the same side of the median notional plane P, and therefore overlap two by two in direction 6, as is also visible on the figure 5a .

Dans cette position simplement posée du boîtier supérieur 1 sur le boîtier inférieur 1, les organes mâles 20 ne coopèrent donc pas avec les organes femelles 18, qui se trouvent de l'autre côté du plan fictif médian P.In this simply placed position of the upper housing 1 on the lower housing 1, the male members 20 therefore do not cooperate with the female organs 18, which are located on the other side of the median imaginary plane P.

Ce type d'empilement, dans lequel les boîtiers 1 adoptent une même position angulaire en rapport à un axe central d'empilement, est préférentiellement retenu dans le cas de l'utilisation de l'ensemble 100 par des robots / automates, permettant la réalisation automatisée d'opérations de pipetage.This type of stacking, in which the boxes 1 adopt the same angular position relative to a central stacking axis, is preferably retained in the case of the use of the assembly 100 by robots / automats, allowing the realization automated pipetting operations.

Au contraire, dans l'empilement de la figure 6, le boîtier supérieur 1 adopte une position retenue par rapport au boîtier inférieur 1, la rétention s'effectuant à l'aide des moyens d'accouplement précités. En effet, au lieu d'adopter une même position angulaire, les deux boîtiers 1 présentent une position angulaire décalée de 180° l'une par rapport à l'autre en rapport à l'axe central d'empilement, ce qui conduit les organes mâles des deux boîtiers à se situer respectivement de part et d'autre du plan fictif médian P. Cela permet ainsi au boîtier supérieur 1 d'avoir ses deux organes mâles 20 coopérant respectivement avec les deux organes femelles 18 du boîtier inférieur, comme cela est également représenté sur la figure 6a au niveau des flancs 14a.On the contrary, in the stacking of the figure 6 , the upper housing 1 adopts a retained position relative to the lower housing 1, the retention being effected using the aforementioned coupling means. Indeed, instead of adopting the same angular position, the two housings 1 have an angular position offset by 180 ° relative to each other in relation to the central stacking axis, which leads the organs male of the two housings to be located respectively on either side of the median notional plane P. This thus allows the upper housing 1 to have its two male members 20 cooperating respectively with the two female members 18 of the lower housing, as is also shown on the figure 6a at the sides 14a.

Ce type d'empilement est préférentiellement retenu dans le cas d'opérations manuelles de pipetage, avec une pipette de prélèvement. Cela permet à l'opérateur de déplacer l'empilement de boîtiers 1 sans risquer de les désolidariser accidentellement les uns des autres.This type of stack is preferably retained in the case of manual pipetting operations, with a sampling pipette. This allows the operator to move the stack of boxes 1 without risking to accidentally separate them from each other.

Les figures 7a à 7c illustrent une manière d'assembler automatiquement deux boîtiers 1 l'un sur l'autre, simplement en les déplaçant l'un vers l'autre selon la direction d'empilement 2. Ils sont tout d'abord alignés selon la direction 2 comme montré sur la figure 7a, jusqu'à ce que le cran 34 arrive en butée contre la rampe 19 de l'organe femelle 18, comme montré sur la figure 7b. La poursuite du déplacement relatif, réalisée par exemple par simple pression sur le boîtier supérieur vers le bas, conduit le cran 34 à se déplacer le long de la rampe 19 prévue à cet effet. Cette rampe 19 a pour but d'écarter la portion d'accrochage 32 vers l'extérieur, selon la direction 6, comme cela a été illustré sur la figure 7c. Cela est possible grâce au pivotement de la patte 20 autour de la liaison 22, selon l'axe de pivotement 23.The Figures 7a to 7c illustrate a way of automatically assembling two boxes 1 one on the other, simply by moving them one towards the other in the stacking direction 2. They are first aligned in the direction 2 as shown on the figure 7a , until the notch 34 abuts against the ramp 19 of the female member 18, as shown on the figure 7b . The continuation of the relative displacement, carried out for example by simple pressure on the upper casing downwards, causes the notch 34 to move along the ramp 19 provided for this purpose. The purpose of this ramp 19 is to spread the attachment portion 32 outward, in the direction 6, as illustrated in the figure 7c . This is possible thanks to the pivoting of the tab 20 around the connection 22, along the pivot axis 23.

Durant l'écartement de la portion d'accrochage 32, les deux cordons de matière formant la liaison pivot 22 se déforment élastiquement en torsion selon l'axe 23. De ce fait, lorsque la pression vers le bas amène le cran 34 en regard de la fente définie par l'organe femelle 18, en sortie de rampe 19, ce cran 34 s'insère automatiquement dans l'organe femelle 18 grâce à la libération d'énergie préalablement emmagasinée par la liaison pivot. La position retenue est alors obtenue, celle-ci étant également dénommée position clipsée.During the spacing of the attachment portion 32, the two beads of material forming the pivot connection 22 elastically deform in torsion along the axis 23. Therefore, when the pressure down brings the notch 34 opposite. the slot defined by the female member 18, at the outlet of the ramp 19, this notch 34 is inserted automatically into the female member 18 thanks to the release of energy previously stored by the pivot link. The retained position is then obtained, this being also known as the clipped position.

Alternativement, l'accouplement des deux boîtiers 1 peut s'effectuer en exerçant une pression sur les portions de préhension 30 de façon à les ramener vers l'intérieur, puis en relâchant cette pression après avoir amené les crans en regard des organes femelles.Alternatively, the two housings 1 can be coupled by exerting pressure on the gripping portions 30 so as to bring them inward, then releasing this pressure after having brought the notches opposite the female organs.

Pour le désaccouplement des deux boîtiers, une même pression 40 schématisée sur la figure 8 peut être exercée sur les portions de préhension 30, afin de retirer les crans en dehors des organes femelles. Une fois le dégagement réalisé, le boîtier supérieur peut être extrait vers le haut, ou bien le boîtier inférieur peut être extrait vers le bas, de manière à effectuer un dépilage.For the uncoupling of the two boxes, the same pressure 40 shown diagrammatically on the figure 8 can be exerted on the gripping portions 30, in order to remove the notches outside the female organs. Once the clearance has been achieved, the upper housing can be extracted upwards, or the lower housing can be extracted downwards, so as to unstack.

Enfin, les figures 9 à 11 illustrent le fait que le chant supérieur du fond creux 4 présente des organes femelles d'accouplement 18' identiques ou similaires à ceux des boîtiers 1, de façon à pouvoir coopérer avec les organes mâles 20 du boîtier 1 le plus bas dans l'empilement. De même, un système de rampe 19' permet l'insertion automatique des crans des organes 20 dans les organes femelles 18'.Finally, the Figures 9 to 11 illustrate the fact that the upper edge of the hollow bottom 4 has female coupling members 18 'identical or similar to those housings 1, so as to be able to cooperate with the male members 20 of the lowest housing 1 in the stack. Likewise, a ramp system 19 ′ allows the automatic insertion of the notches of the organs 20 into the female organs 18 ′.

Bien entendu, diverses modifications peuvent être apportées par l'homme du métier à l'invention qui vient d'être décrite, uniquement à titre d'exemples non limitatifs.Of course, various modifications can be made by those skilled in the art to the invention which has just been described, only by way of nonlimiting examples.

Claims (10)

  1. A casing (1) for supporting sampling cones for a pipetting system, the casing being intended to be stacked with other identical casings along a stacking direction (2), and comprising:
    - a support (10) provided with ports (12) for housing the sampling cones; and
    - first and second opposite flanks (14a, 14b) integral with the support and through which a median imaginary plane (P) integrating the stacking direction (2) passes,
    characterised in that each of the first and second opposite flanks (14a, 14b) is equipped with a mating female member (18) as well as a mating male member (20) arranged substantially symmetrically on either side of said median imaginary plane (P), both mating female members (18) of the first and second opposite flanks (14a, 14b) being arranged on a same side of the median imaginary plane (P) and both mating male members (20) of the first and second opposite flanks being arranged on the other side of the median imaginary plane (P),
    and in that said mating male and female members (20, 18) are designed such that when two identical supporting casings (1) are stacked along the stacking direction (2) with an upper casing and a lower casing both having their male members (20) on a same side of the median imaginary plane (P), the upper casing (1) assumes a laid position in which it is not retained by the lower casing (1) in the stacking direction, and also designed such that when the upper casing (1) and the lower casing (1) have their mating male members (20) respectively on either side of the median imaginary plane (P), the upper casing (1) assumes a retained position in which its two mating male members (20) respectively cooperate with both mating female members (18) of the lower casing (1).
  2. The casing according to claim 1, characterised in that each mating male member (20) comprises a tab pivotably mounted to its associated flank through a pivot joint (22) with an axis (23) substantially orthogonal to the stacking direction (2), the tab having on either side of the pivot joint (22) a gripping portion (30), as well as an anchoring portion (32) terminating with a notch (34).
  3. The casing according to claim 2, characterised in that said pivot joint (22) is made of two elastically torsionally deformable beads of material (26), both beads of material being aligned with each other along the axis (23) of the pivot joint.
  4. The casing according to claim 2 or claim 3, characterised in that the gripping portion (30) upwardly projects beyond its associated flank (14a, 14b), and in that said notch (34) is arranged substantially at a bottom end of this flank.
  5. The casing according to any of claims 2 to 4, characterised in that the female member (18) has in an upper part thereof a ramp (19) enabling, during a relative movement of the upper casing towards the lower casing in the stacking direction (2), its associated male member (20) to be pivoted about said pivot joint (22) by moving the notch (34) along the ramp (19), before the notch (34) is automatically inserted in the female member (18) after this notch has left said ramp.
  6. The casing according to claim 5, characterised in that said automatic insertion of the notch (34) in the mating female member (18) is made by pivoting the mating male member (20) caused by a release of energy previously stored by the pivot joint (22), during the movement of the notch (34) along the ramp (19).
  7. The casing according to any of the preceding claims, characterised in that each mating female member (18) is arranged substantially at a top end of its associated flank, in the proximity of a junction with the support (10) of sampling cones.
  8. The casing according to any of the preceding claims, characterised in that the support has 96 ports (12) for housing the sampling cones.
  9. An assembly (100) comprising several identical casings (1) according to any of the preceding claims, said casings (1) being stacked along the stacking direction (2), in the laid position or in the retained position.
  10. The assembly according to claim 9, characterised in that it includes a hollow bottom (4) arranged at the base of the stack of casings, said hollow bottom (4) comprising female members (18') for mating with the casing (1) which is the lowermost in the stack.
EP17721739.5A 2016-05-12 2017-05-10 Support housing for sampling cones for a pipetting system Active EP3454989B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL17721739T PL3454989T3 (en) 2016-05-12 2017-05-10 Support housing for sampling cones for a pipetting system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1654249A FR3051125B1 (en) 2016-05-12 2016-05-12 SUPPORTING CONES HOLDER HOUSING FOR PIPETTING SYSTEM
PCT/EP2017/061121 WO2017194575A1 (en) 2016-05-12 2017-05-10 Support housing for sampling cones for a pipetting system

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EP3454989A1 EP3454989A1 (en) 2019-03-20
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US (1) US10835902B2 (en)
EP (1) EP3454989B1 (en)
JP (1) JP6929303B2 (en)
KR (1) KR20190008217A (en)
CN (1) CN109070085B (en)
CA (1) CA3024403A1 (en)
ES (1) ES2789677T3 (en)
FR (1) FR3051125B1 (en)
PL (1) PL3454989T3 (en)
WO (1) WO2017194575A1 (en)

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EP3960296A1 (en) * 2020-08-26 2022-03-02 Sartorius Biohit Liquid Handling Oy A holder, a set of parts, and a method of manipulating holders of laboratory consumables

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US2868430A (en) * 1956-08-07 1959-01-13 Container Corp Stacking paperboard tray
DE9216674U1 (en) * 1992-12-08 1993-03-18 Steinbrenner, Bernd, Dr., 6901 Wiesenbach Device for providing preferably sterilized pipette tips
US5882603A (en) * 1997-10-15 1999-03-16 Point Plastics Incorporated Support rack for pipette tips
US7232038B2 (en) * 2004-04-27 2007-06-19 Whitney Steven G Disposable test tube rack
US7658887B2 (en) * 2004-09-02 2010-02-09 Scientific Specialties, Inc. Pipette tip grid with lock mechanism
CN102204017B (en) * 2008-09-09 2014-08-06 莫列斯公司 Flexible use connector
JP6049235B2 (en) * 2009-12-10 2016-12-21 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Combination tip rack
US8906327B2 (en) * 2011-04-08 2014-12-09 Molecular Bioproducts, Inc. Pipette tip stacking tray
EP2623204A1 (en) * 2012-02-03 2013-08-07 F. Hoffmann-La Roche AG Sample handling system
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CN104554989B (en) * 2013-12-23 2021-01-08 上海鸿研物流技术有限公司 Stacking device with tray
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PL3454989T3 (en) 2020-07-13
KR20190008217A (en) 2019-01-23
JP6929303B2 (en) 2021-09-01
FR3051125A1 (en) 2017-11-17
ES2789677T3 (en) 2020-10-26
US20190201908A1 (en) 2019-07-04
JP2019516544A (en) 2019-06-20
EP3454989A1 (en) 2019-03-20
CN109070085A (en) 2018-12-21
FR3051125B1 (en) 2018-06-15
CN109070085B (en) 2020-12-08
WO2017194575A1 (en) 2017-11-16
CA3024403A1 (en) 2017-11-16
US10835902B2 (en) 2020-11-17

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