EP3319632A4 - Verfahren und zusammensetzungen in zusammenhang mit erhöhter influenzavirusproduktion - Google Patents
Verfahren und zusammensetzungen in zusammenhang mit erhöhter influenzavirusproduktion Download PDFInfo
- Publication number
- EP3319632A4 EP3319632A4 EP16821887.3A EP16821887A EP3319632A4 EP 3319632 A4 EP3319632 A4 EP 3319632A4 EP 16821887 A EP16821887 A EP 16821887A EP 3319632 A4 EP3319632 A4 EP 3319632A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- influenza virus
- virus production
- compositions related
- increased influenza
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0684—Cells of the urinary tract or kidneys
- C12N5/0686—Kidney cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
- C12N2310/531—Stem-loop; Hairpin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
- C12N2760/16152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562188817P | 2015-07-06 | 2015-07-06 | |
US201562222243P | 2015-09-23 | 2015-09-23 | |
PCT/US2016/041030 WO2017007784A1 (en) | 2015-07-06 | 2016-07-06 | Methods and compositions related to increased influenza virus production |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3319632A1 EP3319632A1 (de) | 2018-05-16 |
EP3319632A4 true EP3319632A4 (de) | 2019-05-29 |
Family
ID=57686011
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16821887.3A Pending EP3319632A4 (de) | 2015-07-06 | 2016-07-06 | Verfahren und zusammensetzungen in zusammenhang mit erhöhter influenzavirusproduktion |
Country Status (3)
Country | Link |
---|---|
US (1) | US10883086B2 (de) |
EP (1) | EP3319632A4 (de) |
WO (1) | WO2017007784A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4008343A3 (de) * | 2017-03-08 | 2022-08-24 | University of Georgia Research Foundation Inc. | Verfahren und zusammensetzungen in zusammenhang mit erhöhter viraler produktion |
CN108949761A (zh) * | 2018-07-31 | 2018-12-07 | 江苏省人民医院 | ADAMTS6基因及其shRNA序列及在抗人肺癌中的应用 |
WO2023144206A1 (en) * | 2022-01-27 | 2023-08-03 | Sanofi Pasteur | Modified vero cells and methods of using the same for virus production |
CN115896035B (zh) * | 2022-12-22 | 2024-04-16 | 苏州沃美生物有限公司 | 一种应用于病毒扩增的Vero细胞株、其构建方法及应用 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120309814A1 (en) * | 2010-02-22 | 2012-12-06 | Curna, Inc. | Treatment of pyrroline-5-carboxylate reductase 1 (pycr1) related diseases by inhibition of natural antisense transcript to pycr1 |
WO2013166264A2 (en) * | 2012-05-02 | 2013-11-07 | University Of Georgia Research Foundation, Inc. | Methods for altering virus replication |
WO2014123967A2 (en) * | 2013-02-05 | 2014-08-14 | University Of Georgia Research Foundation, Inc. | Cell lines for virus production and methods of use |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3687808A (en) | 1969-08-14 | 1972-08-29 | Univ Leland Stanford Junior | Synthetic polynucleotides |
US20090280567A1 (en) | 2004-02-06 | 2009-11-12 | Dharmacon, Inc. | Stabilized sirnas as transfection controls and silencing reagents |
JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
US8188060B2 (en) | 2008-02-11 | 2012-05-29 | Dharmacon, Inc. | Duplex oligonucleotides with enhanced functionality in gene regulation |
US20120192298A1 (en) * | 2009-07-24 | 2012-07-26 | Sigma Aldrich Co. Llc | Method for genome editing |
US8377901B2 (en) | 2010-07-07 | 2013-02-19 | The University Of Manitoba | Target host factors for treating viral infection |
-
2016
- 2016-07-06 US US15/742,766 patent/US10883086B2/en active Active
- 2016-07-06 WO PCT/US2016/041030 patent/WO2017007784A1/en active Application Filing
- 2016-07-06 EP EP16821887.3A patent/EP3319632A4/de active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120309814A1 (en) * | 2010-02-22 | 2012-12-06 | Curna, Inc. | Treatment of pyrroline-5-carboxylate reductase 1 (pycr1) related diseases by inhibition of natural antisense transcript to pycr1 |
WO2013166264A2 (en) * | 2012-05-02 | 2013-11-07 | University Of Georgia Research Foundation, Inc. | Methods for altering virus replication |
WO2014123967A2 (en) * | 2013-02-05 | 2014-08-14 | University Of Georgia Research Foundation, Inc. | Cell lines for virus production and methods of use |
Non-Patent Citations (4)
Title |
---|
JACKELYN MURRAY ET AL: "A universal mammalian vaccine cell line substrate", PLOS ONE, vol. 12, no. 11, 27 November 2017 (2017-11-27), pages e0188333, XP055543511, DOI: 10.1371/journal.pone.0188333 * |
REVERSADE B ET AL: "Mutations in PYCR1 cause cutis laxa with progeroid features", NATURE GENET, NATURE PUBLISHING GROUP, NEW YORK, US, vol. 41, no. 9, 1 January 2009 (2009-01-01), pages 1016 - 1021, XP008157253, ISSN: 1061-4036, DOI: 10.1038/NG.413 * |
See also references of WO2017007784A1 * |
VAN DER SANDEN SABINE M G ET AL: "Engineering Enhanced Vaccine Cell Lines To Eradicate Vaccine-Preventable Diseases: the Polio End Game", JOURNAL OF VIROLOGY (ONL, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 90, no. 4, 1 February 2016 (2016-02-01), pages 1694 - 1704, XP008180559, ISSN: 1098-5514, DOI: 10.1128/JVI.01464-15 * |
Also Published As
Publication number | Publication date |
---|---|
US20180273908A1 (en) | 2018-09-27 |
US10883086B2 (en) | 2021-01-05 |
EP3319632A1 (de) | 2018-05-16 |
WO2017007784A1 (en) | 2017-01-12 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12N 15/113 20100101ALI20190122BHEP Ipc: C12N 7/00 20060101ALI20190122BHEP Ipc: C12N 15/09 20060101ALI20190122BHEP Ipc: C12N 15/06 20060101ALI20190122BHEP Ipc: A61K 39/145 20060101AFI20190122BHEP Ipc: C12N 5/071 20100101ALI20190122BHEP |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20190502 |
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Ipc: C12N 15/06 20060101ALI20190425BHEP Ipc: A61K 39/145 20060101AFI20190425BHEP Ipc: C12N 15/113 20100101ALI20190425BHEP Ipc: C12N 7/00 20060101ALI20190425BHEP Ipc: C12N 5/071 20100101ALI20190425BHEP Ipc: C12N 15/09 20060101ALI20190425BHEP |
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