EP3004389A4 - Kits et méthodes de dépistage d'une sensibilité à la surdité induite par des médicaments - Google Patents

Kits et méthodes de dépistage d'une sensibilité à la surdité induite par des médicaments Download PDF

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Publication number
EP3004389A4
EP3004389A4 EP14804634.5A EP14804634A EP3004389A4 EP 3004389 A4 EP3004389 A4 EP 3004389A4 EP 14804634 A EP14804634 A EP 14804634A EP 3004389 A4 EP3004389 A4 EP 3004389A4
Authority
EP
European Patent Office
Prior art keywords
kits
methods
detecting drug
induced deafness
susceptibility
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP14804634.5A
Other languages
German (de)
English (en)
Other versions
EP3004389A1 (fr
Inventor
Yanling Kong
Guangxin Xiang
Xiaogang Zhang
Shujian LIANG
Wanli Xing
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tsinghua University
CapitalBio Technology Co Ltd
Original Assignee
Tsinghua University
CapitalBio Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tsinghua University, CapitalBio Corp filed Critical Tsinghua University
Publication of EP3004389A1 publication Critical patent/EP3004389A1/fr
Publication of EP3004389A4 publication Critical patent/EP3004389A4/fr
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP14804634.5A 2013-05-30 2014-05-30 Kits et méthodes de dépistage d'une sensibilité à la surdité induite par des médicaments Ceased EP3004389A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2013102085599A CN103276082A (zh) 2013-05-30 2013-05-30 一种检测药物性耳聋易感基因突变位点的试剂盒
PCT/CN2014/000548 WO2014190762A1 (fr) 2013-05-30 2014-05-30 Kits et méthodes de dépistage d'une sensibilité à la surdité induite par des médicaments

Publications (2)

Publication Number Publication Date
EP3004389A1 EP3004389A1 (fr) 2016-04-13
EP3004389A4 true EP3004389A4 (fr) 2017-02-01

Family

ID=49058697

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14804634.5A Ceased EP3004389A4 (fr) 2013-05-30 2014-05-30 Kits et méthodes de dépistage d'une sensibilité à la surdité induite par des médicaments

Country Status (4)

Country Link
EP (1) EP3004389A4 (fr)
CN (1) CN103276082A (fr)
HK (1) HK1222683A1 (fr)
WO (1) WO2014190762A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103451302A (zh) * 2013-09-11 2013-12-18 步迅 聋病易感基因线粒体12SrDNA 1555A＞G、1494C＞T突变比例检测试剂盒
CN103436625B (zh) * 2013-09-11 2016-03-30 步迅 6聋病易感基因位点分型／突变比例检测试剂盒
CN105506120B (zh) * 2016-01-05 2019-10-18 石玉玲 线粒体突变性耳聋的多重Taqman荧光检测试剂盒
CN106399553B (zh) * 2016-11-09 2020-10-23 上海添音生物科技有限公司 一种基于多重pcr的人线粒体全基因组高通量测序方法
CN107287303A (zh) * 2017-06-28 2017-10-24 浙江大学 线粒体耳聋a1555g突变的荧光定量pcr检测试剂盒及其应用
CN112538523A (zh) * 2019-12-31 2021-03-23 北京毅新博创生物科技有限公司 用于检测与耳聋相关的基因snp的引物组
CN112538524A (zh) * 2019-12-31 2021-03-23 北京毅新博创生物科技有限公司 用于检测与耳聋相关的基因snp的检测产品
CN117512095B (zh) * 2023-11-13 2024-07-30 广州达安临床检验中心有限公司 耳聋相关基因检测引物组、试剂盒及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101768637A (zh) * 2009-11-20 2010-07-07 温州医学院 用于同时检测线粒体dna a1555g和c1494t突变的试剂盒及其使用方法
CN102154481A (zh) * 2011-02-11 2011-08-17 智海生物工程（北京）有限公司 一种线粒体突变检测方法及试剂盒
CN102787169A (zh) * 2012-08-22 2012-11-21 郭丽敏 一种应用于检测线粒体 dna a1555g、c1494t 突变的混合液及试剂盒和检测***
CN103451302A (zh) * 2013-09-11 2013-12-18 步迅 聋病易感基因线粒体12SrDNA 1555A＞G、1494C＞T突变比例检测试剂盒

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060288444A1 (en) * 2004-08-13 2006-12-21 Mccarroll Robert Soybean polymorphisms and methods of genotyping
CN1987463B (zh) * 2006-12-26 2015-04-01 金政策 实时定量TaqMan MGB探针试剂盒
CN101684497B (zh) * 2008-09-23 2011-09-28 中国人民解放军总医院 一种耳聋易感基因筛查试剂盒

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101768637A (zh) * 2009-11-20 2010-07-07 温州医学院 用于同时检测线粒体dna a1555g和c1494t突变的试剂盒及其使用方法
CN102154481A (zh) * 2011-02-11 2011-08-17 智海生物工程（北京）有限公司 一种线粒体突变检测方法及试剂盒
CN102787169A (zh) * 2012-08-22 2012-11-21 郭丽敏 一种应用于检测线粒体 dna a1555g、c1494t 突变的混合液及试剂盒和检测***
CN103451302A (zh) * 2013-09-11 2013-12-18 步迅 聋病易感基因线粒体12SrDNA 1555A＞G、1494C＞T突变比例检测试剂盒

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HUANG SHASHA ET AL: "Rapid identification of aminoglycoside-induced deafness gene mutations using multiplex real-time polymerase chain reaction", INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, vol. 79, no. 7, 2015, pages 1067 - 1072, XP029185034, ISSN: 0165-5876, DOI: 10.1016/J.IJPORL.2015.04.028 *
See also references of WO2014190762A1 *
ZHENG L ET AL: "A novel method of detecting mitochondrial m.1494C>T and m.1555A>G mutations in a single PCR reaction using base-quenched probe", CLINICA CHIMICA ACTA, ELSEVIER BV, AMSTERDAM, NL, vol. 411, no. 23-24, 14 December 2010 (2010-12-14), pages 2114 - 2116, XP027406802, ISSN: 0009-8981, [retrieved on 20101007] *

Also Published As

Publication number Publication date
HK1222683A1 (zh) 2017-07-07
CN103276082A (zh) 2013-09-04
WO2014190762A1 (fr) 2014-12-04
EP3004389A1 (fr) 2016-04-13

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