EP2903583A1 - Transfer device for tapping or delivering a fluid - Google Patents
Transfer device for tapping or delivering a fluidInfo
- Publication number
- EP2903583A1 EP2903583A1 EP13780317.7A EP13780317A EP2903583A1 EP 2903583 A1 EP2903583 A1 EP 2903583A1 EP 13780317 A EP13780317 A EP 13780317A EP 2903583 A1 EP2903583 A1 EP 2903583A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- transfer device
- wall
- closure
- bottle
- extending
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000012546 transfer Methods 0.000 title claims abstract description 69
- 239000012530 fluid Substances 0.000 title claims abstract description 11
- 238000010079 rubber tapping Methods 0.000 title abstract 2
- 230000002093 peripheral effect Effects 0.000 claims description 46
- 230000035515 penetration Effects 0.000 claims description 16
- 238000006073 displacement reaction Methods 0.000 claims description 9
- 238000007789 sealing Methods 0.000 claims description 8
- 230000003993 interaction Effects 0.000 claims description 3
- 208000027418 Wounds and injury Diseases 0.000 abstract description 10
- 230000006378 damage Effects 0.000 abstract description 10
- 208000014674 injury Diseases 0.000 abstract description 10
- 239000012528 membrane Substances 0.000 description 21
- 210000002105 tongue Anatomy 0.000 description 7
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 6
- 229910052782 aluminium Inorganic materials 0.000 description 6
- 238000001802 infusion Methods 0.000 description 6
- 238000002347 injection Methods 0.000 description 6
- 239000007924 injection Substances 0.000 description 6
- 238000003780 insertion Methods 0.000 description 6
- 230000037431 insertion Effects 0.000 description 6
- 239000000126 substance Substances 0.000 description 5
- 229910000831 Steel Inorganic materials 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 239000010959 steel Substances 0.000 description 4
- 239000003440 toxic substance Substances 0.000 description 4
- 239000000443 aerosol Substances 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000000824 cytostatic agent Substances 0.000 description 1
- 230000001085 cytostatic effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 239000013536 elastomeric material Substances 0.000 description 1
- 230000005283 ground state Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2051—Connecting means having tap means, e.g. tap means activated by sliding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1406—Septums, pierceable membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2055—Connecting means having gripping means
Definitions
- Transfer device for removing or transferring a fluid
- the invention relates to a transfer device for withdrawing or transferring a fluid from a bottle closed via a closure, comprising
- a hollow-cylindrical second part which can be adjusted to the first part and has a first wall running transversely to the longitudinal axis direction
- a puncture needle which extends from the first wall and extends in the direction of the first part, permitting puncture of the occlusion
- the first part in the absence of surrounding the closure (state before use) is axially or substantially axially immovable to the second part and in the first part surrounding the closure, the first part to the second part for piercing the closure is adjustable.
- a connector transfer device
- the other container may be another injection bottle, an infusion bag or a syringe.
- these connectors which are also referred to as adapters, can have in the center a steel cannula or a plastic mandrel which is surrounded by a collar forming a hollow cylindrical body which snaps onto the flange-shaped edge with the crimp cap of the vial, in particular consisting of aluminum. From the bottom wall of the collar, the puncture needle goes out in particular in the form of the steel cannula and extends in the longitudinal direction of the hollow cylindrical body.
- Such adapters no longer meet today's requirements for vial adapters, for two reasons. On the one hand, the accident prevention regulation TRBA 250 and a corresponding European directive require the infringement of the safety of such products.
- the second reason is that the plug must be punctured centrally by the puncture needle to ensure leak-tight connection of the vial.
- the vial will tilt when snapped into the collar. This results in a primarily eccentric puncture of the plug.
- the cannula is then forced into a centric position. This leads to the tension of the vial plug, which can lead to leaks next to the cannula. This can be toxic substances such. As cytostatics, to endanger personnel and patients.
- a transfer device of the aforementioned type can be found in EP 1 430 864 B1.
- the transfer device consists of a cap-like outer guide member and a tubular inner guide member which are telescopically displaceable to each other.
- the origins of the inner guide part snap into recesses of the outer guide part that run on the inside.
- tongue-like elements emanating from the inner guide part are bent outward, with the result that the outer guide part is displaced outwards in the region of the recesses, so that the latching between the inner and outer guide parts is released.
- the puncture needle which emanates from the outer guide part, in the delivery state over the opening of the inner guide member freely accessible, so that the same injury sgefahr as in transfer devices, which are integrally formed.
- a transfer device which comprises a hollow in a cylindrical structure axially adjustable needle holder with transfer needle.
- the Structure has a wall-shaped stopper, which can be placed on the opening of a storage container to be pierced and is penetrated by the transfer needle during actuation of the transfer device.
- a transfer device has an actuator in order to be able to axially adjust a first part having a mandrel to a second part surrounding a closure of a bottle.
- the object of the present invention is to provide a transfer device, that is to say a vial connector or adapter, which is particularly resistant to injury. It is also to be ensured according to a further aspect that when unlocking the adapter parts, a removal of the first part of the second part or a withdrawal of the second part of the first part is no longer possible. Also, if possible, the possibility should be created that when puncturing the occlusion of the vial, an expulsion of fluid parts or aerosols from the vial is prevented.
- the object is essentially achieved in that the first part has a second wall extending transversely to the longitudinal axis of the first part, and in that the axial end or substantially axial unadjustability between the first and second part to each other, the distal end of the puncture needle between the first and second the second wall runs.
- the inner or first part has in its distal opening region designated as a second wall intermediate or bottom wall and is latched in the first and second part of the tip of the puncture needle of the intermediate wall of the first part and circumferentially surrounded by the peripheral wall of the second part, It is ensured that a risk of injury is excluded even if a finger gets into the interior of the first part.
- the perforation of the closure which according to the prior art is basically a consisting of aluminum and flanged around the flange edge of the vial membrane is not affected, it is provided that the second wall in the axial extension the puncture needle is broken.
- Tongue-like levers extending from the first part are used to prevent adjustability of the first part to the second part unless a vial is inserted into the first part and the first part is locked to the flange-like edge of the vial. Since the lever elements in the longitudinal direction of the transfer device, so the connector extend, they can absorb large forces without the risk of uncontrolled pivoting occurs. If the transfer device is pushed onto a vial, then the second or inner sections of the lever elements slide along the peripheral surface of the closure and are thereby pivoted radially outwards, with the result that the first or outer sections of the lever elements are pivoted radially inward and thus in reach get to the second part holding the puncture needle.
- first and the second part in the axial or substantially axial unadjustability between the first and second part are latched to each other, preferably emanating from the inside of the peripheral wall of the second part Protrusions engage in recesses of the peripheral wall of the first part.
- the first part is fundamentally adjustable to the second part exclusively in the direction of penetration, that is, withdrawal is not possible.
- the invention is also characterized by a transfer device for removing or transferring a fluid from a bottle closed via a closure, comprising a hollow-cylindrical first part with circumferential wall which can be placed on the bottle and surrounds the closure, a hollow-cylindrical second which can be adjusted to the first part Part with a transverse to the longitudinal axis direction of the first wall, one of the first wall outgoing and extending in the direction of the first part, a piercing of the closure enabling Puncture needle, the first part with the second part in their adjustment to each other in the axial direction interact with each other such that the second part is exclusively or substantially exclusively in the direction of penetration to the first part adjustable, thus retraction is prevented.
- a spirally extending contour is formed as a strip-shaped projection, with the one of the other part, in particular of its peripheral wall, outgoing element such as tongue interacts.
- the contour may have a sawtooth-like profile and the element interacts with the contour projection such as hooks, wherein an interaction takes place such that unimpeded rotation of the first part to the second part takes place exclusively in the penetration direction of the puncture needle.
- the contour protrudes beyond the outer peripheral surface of the first part, that the inner peripheral surface of the second part has at least one recess adapted at least in sections to the contour of the contour, in which the contour is guided.
- a handle extends from the first part, in particular two diametrically opposite one another and from the first part projecting wings, by means of which the first part of the bottle, so the vial is fixable.
- the second part of slots extending in the longitudinal direction of the second part has tongue-shaped elements with protrusions projecting into the interior of the second part, that the protrusions in the axial or substantially axial unobstructability between the first and the second part engaging in recesses provided in the first part which are spaced from the lower edge of the first part such that, when the bottle is latched from the first part, the protrusions interact with the recesses with the bottle or with an outgoing therefrom.
- provision is made in particular for the projections to be ramp-shaped or wedge-shaped in their free ends in such a way that an obliquely extending surface to the longitudinal direction slides along the bottle or its edge.
- the invention provides that the opening-side edge of the first part has inwardly projecting projections for grasping a flange-like edge surrounding the opening of the bottle, wherein unlocking between the first portions of the lever elements and the second part before grasping the flange-like edge is omitted.
- the first part snaps onto the vial, i. H. its flange-shaped edge.
- the intermediate wall which virtually shields the tip of the puncture needle when the transfer device is unused, is brought into contact with the first part on the outside of the closure when the first part is inserted into the second part or the second part is pushed onto the first part, so that the required power transmission is made possible to move the first part to the second part.
- an element extending in the axial extension of the puncture needle emanating from the second wall pierces the puncture needle peripherally sealing element such as membrane or plug.
- the corresponding elements are in particular those made of elastomeric material, which is punctured by the puncture needle and simultaneously pressed against the closure of the vial.
- the corresponding elements such as membrane or plug then seal the puncture needle circumferentially. At the same time a sealing against the Outside of the lock. This ensures that the contents of the vial can not escape when piercing the components.
- a two-piece connector cap wherein the parts are arranged telescopically against each other and mutually adjustable.
- the inner or first part has barbs for snapping the vial head and the outer or second part has the puncture needle for perforating the closure of the vial.
- the inner part protrudes from the outer part, wherein the tip of the cannula is protected behind the wall of the inner or first part to be designated as the bottom.
- lever-like locking devices are provided in the circumference of the inner part, which prevent the inner part can be pushed into the outer part. Only with complete insertion of the vial head into the inner part, the locking levers are pushed outwards by the vial head. They pivot about an axis, so that in the direction of the outer part extending end, which otherwise locks the insertion of the inner part into the outer, is pivoted inwards and thus the way for the adjustment as insertion or screwing of the inner part in the outer part of the vial adapter releases.
- the puncture needle punctures the closure, so the diaphragm of the vial stopper.
- elastomeric components can be arranged in the inner wall of the inner part, which are punctured by the puncture needle and simultaneously pressed against the outside of the closure of the vial. These components seal both around the cannula and against the occlusion of the vial, so that when piercing the substances from the vial can not escape into the open.
- Fig. 1 shows a first embodiment of a transfer device
- FIG. 2 shows the transfer device according to FIG. 1 before unlocking
- FIGS. 1 and 2 shows the transfer device according to FIGS. 1 and 2 after unlocking
- FIGS. 1 to 3 shows the transfer device according to FIGS. 1 to 3 before the penetration
- FIG. 5 shows the transfer device according to FIGS. 1 to 4 in the end position
- FIG. 7 shows a third embodiment of a transfer device, a fourth embodiment of a transfer device before penetration of a closure,
- FIG. 9 shows the transfer device according to FIG. 8 during the penetration,
- FIGS. 8 and 9 shows the transfer device according to FIGS. 8 and 9 at the end of the penetration
- FIG. 11 is a side view of a first part of the transfer device according to FIGS. 8 to 10,
- FIG. 12 is the first part of FIG. 11 in plan view
- FIG. 13 is a side view of a second part of the transfer device according to FIGS. 8 to 10,
- FIG. 17 shows the transfer device according to FIG. 16 in a position partly pushed onto a bottle
- transfer devices are shown, by means of which of a bottle or vial, a so-called vial, fluids such as dry substances or liquids such as water or solvent for infusion or injection purposes be mixed before their application or administration.
- fluids such as dry substances or liquids such as water or solvent for infusion or injection purposes be mixed before their application or administration.
- Corresponding transfer devices are also referred to as connectors or adapters.
- a corresponding transfer device is required to puncture by means of a puncture needle - such as steel cannula - the closure of the vial, and then via the transfer device, the vial to be removed fluid z.
- a puncture needle - such as steel cannula - the closure of the vial
- the transfer devices to be taken from the figures have telescopically arranged and mutually adjustable parts, which are referred to as first and second part or inner or outer part.
- first and second part or inner or outer part For the sake of simplicity, the transfer device will hereinafter be referred to as a connector and the vial to be connected to it as a vial.
- the first part is also called Vialhalter and the second part as a cannula holder.
- a first embodiment of a connector 10 which is composed of an inner or first part 12 and a second or outer part 14 which are arranged telescopically to each other and axially displaceable to each other.
- the inner part 12 and the outer part 14 is in particular an injection molded part and consists of a suitable plastic.
- the inner part 12 has a peripheral wall 16 which has a hollow cylindrical shape and comprises tongue-like and thus movable sections 18 which are peripherally bounded by slots and have projections 20 projecting inward in their free ends in order to engage behind a flange-like edge 22 of a vial 24 in the use position.
- the flange-like edge 22 is an opening of the vial 24, which is closed by a sealing plug 26.
- an aluminum crimp cap is applied. On this can be a flip-off cap made of plastic.
- This flip-off cap is withdrawn from the aluminum crimp cap to form a "hole" in the center of the aluminum crimp cap to reveal the plug 26.
- This preparation for opening the aluminum crimp cap, hereinafter referred to as diaphragm 28 is typically performed prior to piercing with a cannula, as the plastic flip-off cap must be removed, to which extent reference is made to well-known constructions.
- the inner or first part 12 furthermore has, at a distance from the latching projections 20, an intermediate wall 30, which runs transversely to the longitudinal axis of the first part 12 and is referred to as a second wall, which is also referred to as a bottom wall, the same way web-like sections of the circumferential wall 16 extend over the intermediate wall. or bottom wall 30 extend in the direction of the second part 14, as the drawings illustrate. Further, it is apparent from the illustrations that the outside of the peripheral wall 16 has a sawtooth-like notch 32 to serve as barbs for explanatory projections of the outer or second part 14, hereinafter.
- each lever element 34, 36 - also called lever - thus consists of a first or outer portion 38 and a second or inner portion 40, wherein in the ground state, ie when the levers 34, 36 no radial forces act, the outer portion 38th partially protrudes laterally beyond the outer surface of the peripheral wall 16, whereas the inner portion 14 protrudes with its hook-shaped end 42 in sections into the interior of the first part 12.
- the outer or second part 14 likewise has a circumferential wall 44 which forms a hollow cylinder geometry and is delimited by a bottom wall 46 to be designated as the first wall, of which on the one hand a cannula 48 extending in the longitudinal axis direction of the connector 10 in the direction of the first part runs in opposite directions a so-called break-off connector 50 goes out, which consists of plastic and in which the cannula 48 is glued.
- the break-off connector 50 has a thinned predetermined breaking point 52 to break the tip 54 when the connector 10 is used. In that regard, reference is also made to known constructions.
- first wall or bottom wall 46 has a flange 55 protruding beyond the circumferential wall 44 or a flange-like handle, so that, basically, a hat geometry results for the second part 14.
- peripheral wall 44 of the outer part 14 also preferably distributed uniformly around the circumference, provided by slots tongue-like portions 56, 58 are present, which have hook-shaped projections 60 in their free ends to lock with the inner part 12 can.
- the projections 60 protrude upon delivery of the connector 10 in above the second wall 30 projecting and in extension of the peripheral wall 16 extending web-like portions 62, 64 existing recesses (detent recesses) 66, 68 latching. This ensures that the inner part 12 can not be pulled out of the outer part 14 in order to release the parts 12, 14.
- the outer part 14 is supported on the outer sections 38 of the tongue-like lever elements 34.
- the distal end ie the tip 74 of the cannula 48, extends between the bottom wall 30 of the inner part 12 and the bottom wall 46 of the outer part 14, so that notwithstanding the fact that the bottom wall 30 has an opening 76 in this area, There is no risk of injury to a user if his finger should accidentally enter the interior of the inner part 12 of the connector 14.
- the distal end extends within the bottom wall 30 of the inner part 12. In that regard, this position of the invention is understood or grasped by the invention that the distal end between the bottom walls 30, 46, as the first wall and the second wall is positioned.
- Fig. 1 the connector 10 is placed on the edge 12 in the delivery state for emptying the vial 24. Then there is a relative movement between the vial 24 and the connector 10, without a relative movement between the inner and outer part 12, 14 takes place, as a comparison of Figures 1 and 2 occupied. Because the inner part 12 can not be pushed into the outer part 14, as this is prevented by the lever members 34, 36, since these are supported with their outer portions 38 at the boundary of the recess 70, ie on the wall 72.
- Fig. 2 the position is shown in which the connector 10 is located shortly before unlocking. In this position, the locking projections 20 of the tongue-like portions 18 of the peripheral wall 16 do not yet underline the underside 78 of the edge 22 of the vial 24.
- FIG. 3 snap the locking projections 20 under the flange-like edge 22 of the vial 24.
- the lever members 34, 36 are pivoted, since the projection 42 along the peripheral surface of the edge 22 of the vial 24 is guided along with the result that thereby pivoting of the lever 34 shown on the left in the drawing takes place in a clockwise direction.
- the clear distance between the projection 42 of the lever 34 in the basic position of the connector 10 (Fig. 1) to the central axis 80 of the connector 10 is smaller than half the diameter of the edge 22 of the vial 24 with the result that by interaction of the Projection 42 with the peripheral surface of the edge 22, the desired pivoting of the lever 34 is made possible.
- the vial 24 is pushed into the inner part 12 until the membrane 28 of the closure of the vial 24 bears against the second wall, that is to say the bottom wall 30, as FIG. 4 illustrates. In this position, the cannula 48 does not perforate the membrane 28 yet. If the vial 24 with the inner part 12 is then displaced into the outer part 14, the tip, that is to say the distal end 74 of the cannula 48, penetrates the membrane 28 or its hole. At the same time, the locking projection 60 of the tongue-like portions 56, 58 of the peripheral wall 44 of the outer part 14 comes into engagement with the locking receptacles 66, 68 and slides along the peripheral surface of the Peripheral wall 16 and can gradually lock with the sawtooth projections 18.
- Fig. 5 the final state is shown, d. H. the cannula 48 with its tip 74 has penetrated into the vial 24 to the required extent. At the same time latch the locking projections 60 in locking recesses 82 in the peripheral wall 16 of the first part 12, so that a release between the inner and outer part 12, 14 is no longer possible. Also, in this position, as can be seen from FIG. 5, bending away of the tongue-like sections 18 of the peripheral wall 16 radially outward is no longer possible, so that detachment from the vial 24 is precluded. Furthermore, in the end position according to FIG. 5, the end region of the outer section 38 of the lever elements 34 engages in corresponding recesses 84 of the bottom wall 46 of the outer part 14. Thus, the lever member 34 can be formed relatively long, without resulting in the height and thus the compactness of the connector 10 disadvantages.
- FIGS. 6 and 7 differ from those of FIGS. 1 to 5 in that elements which consist of the bottom wall 30, that is to say the second wall, in particular of an elastomer material, are in the form of a hat-shaped membrane 86 (FIG. 7). or a plug 88 ( Figure 6) emanating from the cannula 48, d. H. its tip 74 are pierced before penetrating the membrane 28 of the closure of the vial 24, wherein the elements 86, 88 on the one hand tightly around the cannula 48 and on the other hand allow a seal against the membrane 28 with the result that when piercing the membrane 28 contents of the vial 24 can not escape to the outside. This is particularly advantageous if there are 24 toxic substances in the vial.
- FIGS. 8 to 15 A further preferred embodiment of a connector 100 can be seen in FIGS. 8 to 15.
- the structure and operation of the connector 100 in particular with respect to the possibility of the inner or first part 12 to adjust to the second or outer part 14, when the inner part 12 on the vial 24, ie on the edge 22, is latched, reference is made to the features and explanations described above. Also, the same reference numerals are used for the same elements in principle.
- the needle holder In order to allow an axial adjustment of the inner part 12, so the vial holder, to the outer part 14, the needle holder, according to the embodiment of FIGS. 8 to 16 a rotational movement between the inner and outer part 12, 14 is performed.
- the inner part 12 has a spiral-shaped contour 102, which starts from the peripheral wall 16 of the inner part 12 and thus projects beyond its circumferential outer surface 116.
- the spiral contour 102 which may have a strip-shaped course, thus forms a screw thread or a section of such, as is apparent in particular from FIG. 11.
- This contour 102 is interrupted in the region of the slots which delimit the sections 18 and the lever elements 34, 36. This is also clear from FIG. 11.
- a screw can also be provided several screw threads.
- the contour 102 extending coaxially with the longitudinal axis 118 of the vial mount has a sawtooth structure for latching engagement with a tongue-like element 120 which is cut free in the circumferential wall 44 of the outer part 14 and has one or more projections 122 extending in the direction of the contour 102, the one or more with the sawtooth profiling of the contour 102 such cooperate, that in the embodiment, the outer part 14 can be rotated exclusively in a clockwise direction, whereby the cannula 48 is adjusted in the direction of the sealing plug 26 in order to pierce the membrane 28 can.
- a counterclockwise rotation is not possible since in this case the hook-shaped projection 122 engages with correspondingly geometrically aligned projections of the sawtooth-shaped profiling of the contour 102.
- the screw thread or a portion of such a following contour 102 extends within a matching recess 124 in the peripheral wall 44 of the outer part 14, which thus forms a guide during the rotational movement.
- FIG. 8 shows the position in which the outer sections 38 of the lever elements 34, 36 are pivoted inwards, so that rotation of the outer part 14 towards the inner part 12 becomes possible.
- the starting position is shown in which a rotation of the outer part 14 to the inner part 12 can take place in order to adjust the cannula 48 in the direction of the diaphragm 28 axially.
- the outer part 14 has been adjusted relative to the inner part 12, so that the membrane 28 is already pierced by the tip 54 of the cannula 48.
- Fig. 10 reflects the end position, in which the cannula 44 in desired extent the membrane 28 has penetrated. At the same time a locking of the outer part 14 with the first part 12 is possible in this position.
- FIGS. 16 to 20 show a further embodiment of a transfer device 200 to be emphasized, which obeys the teaching according to the invention. Therefore, the same reference numerals are basically used according to FIGS. 1 to 15 for the same elements.
- the transfer device hereinafter referred to as connector 200 thus consists of the inner or first part 12 and the outer or second part 14, which are axially displaceable to each other.
- the second or outer part 14 has a plurality of preferably uniformly circumferentially distributed tongue-shaped resilient elements limited by slots 202 , 204, hereinafter referred to as tongues.
- the tongues 202, 204 have in their ends inwardly, ie in the direction of the central axis 80 of the connector 200 extending latching projections 206, 208, which may have a wedge or ramp-shaped geometry.
- latching projections 206, 208 which may have a wedge or ramp-shaped geometry.
- the locking projections 206, 208 protrude into corresponding recesses 210, 212 in the peripheral wall of the inner part 12.
- the latching projections 206, 208 remain in the recesses 210, 212 of the inner part 12 until the inwardly directed projections 20 of the first part 12 behind the lower edge of the flange-like edge 22 of the vial 24.
- the flange-like edge 22 another element enabling a fixing of the connector 200 is covered.
- FIG. 17 a position is shown, in which the first part 12 with the free edge of the inwardly projecting projections 20, the underside of the edge 22 of the vial 24 or a vial surrounding the closure 24 behind.
- the latching projections 206, 208 with the spring-like tongue elements 202, 204 are bent outwardly by cooperation with the upper side or the upper corner of the edge 22, as FIG. 18 illustrates.
- the distance between the recesses 210, 212 to the latching projections 20 of the first part 12 engaging behind the underside of the edge 22 of the vial is selected such that, when the first part 12 is properly fixed to the vial 24, the latching projections 206, 208 of the second part 14 along the peripheral upper edge of the flange-like edge 22 can slide when acting on the second part 14, a force in the direction of the first part 12.
- the latching projections 206, 208 along the outside of the first part 12 are displaced until the latching projections 206, 208 due to the resilient properties of the tongue elements 202, 204, the lower edge of the first Part 12 behind, as can be seen from Fig. 20, in which the vial 24 is not shown in the drawing.
- the connector 200 fulfills the requirement that in the unused state or in the case of incorrectly surrounding the vial 24, the cannula 48 with its tip 76 is not freely accessible, ie a risk of injury is ruled out. Only when the first part 12 properly surrounds the closure region of the vial 24, a unlocking and thus activating the connector 200 is such that an axial adjustment between the first and second part 12, 14 is made possible and thus the cannula 48 can be adjusted in the direction of the membrane 28 of the sealing plug 26 for penetrating this, as can be seen from FIGS. 16 to 20, which are self-explanatory.
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Description
Claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL13780317T PL2903583T3 (en) | 2012-10-01 | 2013-09-30 | Transfer device for tapping or delivering a fluid |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102012109322 | 2012-10-01 | ||
DE201210113002 DE102012113002B4 (en) | 2012-10-01 | 2012-12-21 | Transfer device for removing or transferring a fluid |
PCT/EP2013/070320 WO2014053430A1 (en) | 2012-10-01 | 2013-09-30 | Transfer device for tapping or delivering a fluid |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2903583A1 true EP2903583A1 (en) | 2015-08-12 |
EP2903583B1 EP2903583B1 (en) | 2016-11-09 |
Family
ID=50276184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13780317.7A Active EP2903583B1 (en) | 2012-10-01 | 2013-09-30 | Transfer device for tapping or delivering a fluid |
Country Status (8)
Country | Link |
---|---|
US (1) | US10058482B2 (en) |
EP (1) | EP2903583B1 (en) |
DE (1) | DE102012113002B4 (en) |
DK (1) | DK2903583T3 (en) |
ES (1) | ES2615479T3 (en) |
PL (1) | PL2903583T3 (en) |
PT (1) | PT2903583T (en) |
WO (1) | WO2014053430A1 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7547300B2 (en) | 2006-04-12 | 2009-06-16 | Icu Medical, Inc. | Vial adaptor for regulating pressure |
CA3176437A1 (en) | 2011-08-18 | 2013-02-21 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
AU2013204180B2 (en) | 2012-03-22 | 2016-07-21 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
DE102012113002B4 (en) | 2012-10-01 | 2014-04-30 | Medac Gesellschaft für klinische Spezialpräparate mbH | Transfer device for removing or transferring a fluid |
US9089475B2 (en) | 2013-01-23 | 2015-07-28 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
CN105722493B (en) | 2013-07-19 | 2019-10-11 | 伊库医学有限公司 | Pressure adjusts fluid delivery system and method |
DE102014104281B3 (en) * | 2014-03-27 | 2015-09-10 | Medac Gesellschaft für klinische Spezialpräparate mbH | transfer device |
DE102015201275A1 (en) * | 2015-01-26 | 2016-07-28 | Bayer Pharma AG | Device for transferring a liquid between a storage container and at least one further use container |
WO2017132588A1 (en) | 2016-01-29 | 2017-08-03 | Icu Medical, Inc. | Pressure-regulating vial adaptors |
DE102016110569B3 (en) | 2016-06-08 | 2017-10-26 | Sfm Medical Devices Gmbh | adapter |
WO2018064206A1 (en) * | 2016-09-30 | 2018-04-05 | Icu Medical, Inc. | Pressure-regulating vial access devices and methods |
EP3542772B1 (en) * | 2016-11-21 | 2023-08-16 | Terumo Kabushiki Kaisha | Drug solution filling unit, drug solution filling set, and filling adapter |
IL249408A0 (en) | 2016-12-06 | 2017-03-30 | Medimop Medical Projects Ltd | Liquid transfer device for use with infusion liquid container and pincers-like hand tool for use therewith for releasing intact drug vial therefrom |
IL251458A0 (en) * | 2017-03-29 | 2017-06-29 | Medimop Medical Projects Ltd | User actuated liquid drug transfer devices for use in ready-to-use (rtu) liquid drug transfer assemblages |
EP3687323B1 (en) * | 2017-09-27 | 2021-12-01 | Philip Morris Products S.A. | Support element for aerosol generating article |
IL254802A0 (en) | 2017-09-29 | 2017-12-31 | Medimop Medical Projects Ltd | Dual vial adapter assemblages with twin vented female vial adapters |
JP1630477S (en) | 2018-07-06 | 2019-05-07 | ||
US11850320B2 (en) | 2018-12-20 | 2023-12-26 | Asp Global Manufacturing Gmbh | Liquid-chemical sterilization system with biological indicator |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1173370B (en) * | 1984-02-24 | 1987-06-24 | Erba Farmitalia | SAFETY DEVICE TO CONNECT A SYRINGE TO THE MOUTH OF A BOTTLE CONTAINING A DRUG OR A TUBE FOR DISPENSING THE SYRINGE DRUG |
IT1231892B (en) | 1987-10-14 | 1992-01-15 | Farmitalia Carlo Erba S P A Mi | APPARATUS WITH SAFETY LOCKING ORGANS FOR CONNECTION OF A SYRINGE TO A BOTTLE CONTAINING A DRUG |
GB9701413D0 (en) | 1997-01-24 | 1997-03-12 | Smithkline Beecham Biolog | Novel device |
FR2789369B1 (en) | 1999-02-10 | 2001-04-27 | Biodome | CONNECTION DEVICE BETWEEN A CONTAINER AND A CONTAINER AND READY-TO-USE ASSEMBLY COMPRISING SUCH A DEVICE |
JP4341239B2 (en) | 2002-12-19 | 2009-10-07 | ニプロ株式会社 | Liquid transfer tool |
FR2867396B1 (en) | 2004-03-10 | 2006-12-22 | P2A | PERFORATING PERFORMER WITH STERILE CONNECTION |
DE102005006771A1 (en) * | 2005-02-15 | 2006-08-17 | Disetronic Licensing Ag | Sterile link fitting for the transfer of insulin or other medication from a reservoir to a container e.g. bottle comprises retractable needle unit |
US8241265B2 (en) | 2007-08-01 | 2012-08-14 | Hospira, Inc. | Medicament admixing system |
WO2011140596A1 (en) | 2010-05-11 | 2011-11-17 | Noble House Group Pty. Ltd. | Medical sampling port |
DE102012113002B4 (en) | 2012-10-01 | 2014-04-30 | Medac Gesellschaft für klinische Spezialpräparate mbH | Transfer device for removing or transferring a fluid |
US9033949B2 (en) * | 2012-11-27 | 2015-05-19 | Bang & Olufsen Medicom A/S | Needle protection device |
-
2012
- 2012-12-21 DE DE201210113002 patent/DE102012113002B4/en active Active
-
2013
- 2013-09-30 EP EP13780317.7A patent/EP2903583B1/en active Active
- 2013-09-30 WO PCT/EP2013/070320 patent/WO2014053430A1/en active Application Filing
- 2013-09-30 ES ES13780317.7T patent/ES2615479T3/en active Active
- 2013-09-30 DK DK13780317.7T patent/DK2903583T3/en active
- 2013-09-30 US US14/432,809 patent/US10058482B2/en active Active
- 2013-09-30 PL PL13780317T patent/PL2903583T3/en unknown
- 2013-09-30 PT PT137803177T patent/PT2903583T/en unknown
Non-Patent Citations (1)
Title |
---|
See references of WO2014053430A1 * |
Also Published As
Publication number | Publication date |
---|---|
US20150209232A1 (en) | 2015-07-30 |
DE102012113002B4 (en) | 2014-04-30 |
WO2014053430A1 (en) | 2014-04-10 |
ES2615479T3 (en) | 2017-06-07 |
DK2903583T3 (en) | 2017-02-13 |
PL2903583T3 (en) | 2017-04-28 |
US10058482B2 (en) | 2018-08-28 |
EP2903583B1 (en) | 2016-11-09 |
PT2903583T (en) | 2017-02-13 |
DE102012113002A1 (en) | 2014-04-03 |
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