EP2536406A4 - Wismut-thiole als antiseptika zur biomedizinischen verwendung einschliesslich behandlung bakterieller biofilme und anderer verwendungen - Google Patents

Wismut-thiole als antiseptika zur biomedizinischen verwendung einschliesslich behandlung bakterieller biofilme und anderer verwendungen

Info

Publication number
EP2536406A4
EP2536406A4 EP11740333.7A EP11740333A EP2536406A4 EP 2536406 A4 EP2536406 A4 EP 2536406A4 EP 11740333 A EP11740333 A EP 11740333A EP 2536406 A4 EP2536406 A4 EP 2536406A4
Authority
EP
European Patent Office
Prior art keywords
antiseptics
thiols
bismuth
including treatment
bacterial biofilms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP11740333.7A
Other languages
English (en)
French (fr)
Other versions
EP2536406A2 (de
Inventor
Brett Hugh James Baker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbion Corp
Original Assignee
Microbion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2010/023108 external-priority patent/WO2010091124A2/en
Application filed by Microbion Corp filed Critical Microbion Corp
Publication of EP2536406A2 publication Critical patent/EP2536406A2/de
Publication of EP2536406A4 publication Critical patent/EP2536406A4/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
    • A01N55/02—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/29—Antimony or bismuth compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/245—Bismuth; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Inorganic Chemistry (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Child & Adolescent Psychology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Virology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP11740333.7A 2010-02-03 2011-02-03 Wismut-thiole als antiseptika zur biomedizinischen verwendung einschliesslich behandlung bakterieller biofilme und anderer verwendungen Pending EP2536406A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US2010/023108 WO2010091124A2 (en) 2009-02-03 2010-02-03 Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications
US37318810P 2010-08-12 2010-08-12
PCT/US2011/023549 WO2011097347A2 (en) 2010-02-03 2011-02-03 Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses

Publications (2)

Publication Number Publication Date
EP2536406A2 EP2536406A2 (de) 2012-12-26
EP2536406A4 true EP2536406A4 (de) 2014-04-09

Family

ID=51355699

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11740333.7A Pending EP2536406A4 (de) 2010-02-03 2011-02-03 Wismut-thiole als antiseptika zur biomedizinischen verwendung einschliesslich behandlung bakterieller biofilme und anderer verwendungen

Country Status (7)

Country Link
EP (1) EP2536406A4 (de)
JP (1) JP2013518895A (de)
CN (2) CN103079557A (de)
AU (1) AU2011212941B2 (de)
CA (1) CA2788669C (de)
MX (1) MX346409B (de)
WO (1) WO2011097347A2 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005072710A2 (en) 2004-01-28 2005-08-11 Johns Hopkins University Drugs and gene carrier particles that rapidly move through mucous barriers
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
EP2844295A1 (de) 2012-05-03 2015-03-11 Kala Pharmaceuticals, Inc. Pharmazeutische nanopartikel mit verbessertem mukosalem transport
WO2013166408A1 (en) 2012-05-03 2013-11-07 Kala Pharmaceuticals, Inc. Pharmaceutical nanoparticles showing improved mucosal transport
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
WO2014052973A1 (en) * 2012-09-28 2014-04-03 Stelo Technologies Methods of making silver nanoparticles and their applications
CN103667119B (zh) * 2013-11-26 2015-07-29 浙江大学 用于降解乙硫醇的菌株及其培养方法和应用
US11039621B2 (en) 2014-02-19 2021-06-22 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US9622483B2 (en) 2014-02-19 2017-04-18 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US11039620B2 (en) 2014-02-19 2021-06-22 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
AU2014385792B2 (en) 2014-03-07 2021-01-21 Tuffley, Mark DR Composition and method for enhancing wound healing
CN105572126B (zh) * 2015-04-07 2018-10-23 湖南华纳大药厂股份有限公司 一种胶体果胶铋药物组合物
US10045950B2 (en) * 2015-04-08 2018-08-14 BioMendics, LLC Formulation and process for modulating wound healing
WO2017145142A1 (en) 2016-02-25 2017-08-31 Nobio Ltd. Micro and nanoparticulate compositions comprising anti-microbially active groups
BR112019011660A2 (pt) * 2016-12-05 2019-10-22 Technophage Investig E Desenvolvimento Em Biotecnologia Sa composições de bacteriófagos que compreendem fagos antibacterianos respiratórios e métodos de uso das mesmas
WO2018112511A1 (en) * 2016-12-22 2018-06-28 Whiteley Corporation Pty Ltd Biofilm disrupting composition
WO2019043714A1 (en) 2017-08-30 2019-03-07 Nobio Ltd. ANTIMICROBIAL PARTICLES AND METHODS OF USE THEREOF
EP3485869B1 (de) * 2017-11-16 2021-07-21 DSM IP Assets B.V. Verwendung von phytantriol als antimikrobielles mittel zur erhaltung einer zusammensetzung
CN110387416B (zh) * 2018-04-16 2022-06-17 华东理工大学 可控聚合调控功能的纳米金双探针体系及其应用
CN112788950A (zh) * 2018-07-31 2021-05-11 微生物公司 用于治疗伤口的铋-硫醇组合物和方法
US11464749B2 (en) * 2018-07-31 2022-10-11 Microbion Corporation Bismuth-thiol compositions and methods of use
CN110870874A (zh) * 2018-08-13 2020-03-10 中山大学 具有抗菌效果的药物及其应用
KR102054341B1 (ko) * 2019-06-20 2019-12-10 한국지질자원연구원 비흡수성 항생물질 및 점토광물의 복합체를 포함하는 항생제 내성인 헬리코박터 파일로리 제균을 위한 경구투여용 약학적 조성물
SG11202108262VA (en) * 2019-01-31 2021-08-30 Pulsethera Corp Bacterialcidal methods and compositions
WO2020191076A1 (en) * 2019-03-18 2020-09-24 Cedars-Sinai Medical Center Compositions and methods to treat gastrointestinal diseases and disorders
CN112425608B (zh) * 2019-08-23 2023-07-21 香港科技大学 弹性蛋白酶抑制剂、具有抗生物膜活性的抑菌剂
CN111034711B (zh) * 2019-12-19 2022-04-05 海南一龄医疗产业发展有限公司 高效清除细胞培养过程中微生物污染的组合物及方法
CN111175103B (zh) * 2020-01-16 2023-07-04 江西业力医疗器械有限公司 一种真菌性***炎荧光检测的白带样本前处理液及其制备方法
US20230124862A1 (en) * 2020-03-24 2023-04-20 Jeffrey W. MILLARD Bismuth thiol compounds and compositions and methods of treating microbial co-infections
CN113712842B (zh) * 2020-05-25 2023-06-13 基元美业生物科技(上海)有限公司 一种组合物及其在制备化妆品及医疗器械中的应用
CN112618716B (zh) * 2021-01-11 2022-04-08 福州大学 一种光动力联合溶菌酶抗菌方法
CN113930462A (zh) * 2021-10-19 2022-01-14 江南大学 高丝氨酸内酯信号分子促进碳链延长微生物合成己酸的方法
CN114984746B (zh) * 2022-08-05 2022-11-01 山东建筑大学 一种消杀剂及养殖废水池VOCs废气处理***方法和装置
CN115532295B (zh) * 2022-09-27 2023-07-25 苏州大学 含有Zn-N-C活性中心的纳米材料在去除细菌生物膜中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020197282A1 (en) * 1999-02-23 2002-12-26 Mohseni Saeed H. Sonic method of enhancing chemical reactions to provide uniform, non-agglomerated particles
WO2010091124A2 (en) * 2009-02-03 2010-08-12 Microbion Corporation Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6086921A (en) * 1995-04-25 2000-07-11 Wintrop-University Hospital Metal/thiol biocides
US5999828A (en) * 1997-03-19 1999-12-07 Qualcomm Incorporated Multi-user wireless telephone having dual echo cancellers
US6380248B1 (en) * 1998-02-04 2002-04-30 Winthrop University Hospital Metal-thiols as immunomodulating agents
US7381751B2 (en) * 2003-08-26 2008-06-03 Shantha Sarangapani Antimicrobial composition for medical articles
US8343536B2 (en) * 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020197282A1 (en) * 1999-02-23 2002-12-26 Mohseni Saeed H. Sonic method of enhancing chemical reactions to provide uniform, non-agglomerated particles
WO2010091124A2 (en) * 2009-02-03 2010-08-12 Microbion Corporation Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications

Also Published As

Publication number Publication date
MX2012009054A (es) 2012-12-17
CA2788669A1 (en) 2011-08-11
WO2011097347A3 (en) 2011-12-22
CA2788669C (en) 2021-05-25
MX346409B (es) 2017-03-17
AU2011212941B2 (en) 2016-03-03
CN107308186A (zh) 2017-11-03
WO2011097347A2 (en) 2011-08-11
EP2536406A2 (de) 2012-12-26
JP2013518895A (ja) 2013-05-23
AU2011212941A1 (en) 2012-09-27
CN103079557A (zh) 2013-05-01

Similar Documents

Publication Publication Date Title
EP2536406A4 (de) Wismut-thiole als antiseptika zur biomedizinischen verwendung einschliesslich behandlung bakterieller biofilme und anderer verwendungen
EP2629736A4 (de) Gewebebehandlung
ZA201208413B (en) Skin treatment composition
ZA201005798B (en) Treatment of microbial infections
EP2654745A4 (de) Zusammensetzung zur behandlung von hautleiden
GB201217097D0 (en) Treatment of bacterial infection
HK1183454A1 (zh) 用於治療微生物感染的羅望子種子多糖
IL223289A0 (en) Treatment of type 2 diabetes
AU2011348474A1 (en) Antimicrobial composition having skin care properties
HK1180182A1 (en) Platelet-derived growth factor compositions and methods for the treatment of tendinopathies
IL225755B (en) amido derivatives - 6 of epoxymorphinans - a5, 4 for the treatment of pain
ZA201208568B (en) Skin treatment composition
WO2011156820A9 (en) Compositions, methods and uses for treatment of type 1 diabetes
EP2650292A4 (de) Thiazolaminderivat und seine verwendung als medikament gegen picornaviridae-infektionen
ZA201204249B (en) Treatment of microbial infections
EP2529728A4 (de) Pharmazeutische zusammensetzungen zur behandlung von bakterieninfektionen
EP2665738A4 (de) Verbindungen zur verwendung bei der behandlung bakterieller infektionen
AU2010901811A0 (en) Avian-Based Treatment for Microbial Infection
AU2010904571A0 (en) Skin Treatment Formulation
GB0807781D0 (en) Treatment of bacterial infection
GB0801768D0 (en) Treatment of microbial infections
AU2009904943A0 (en) Skin Treatment Formulation
AU2012902449A0 (en) Novel animal infection treatment and prophylaxis
AU2010900846A0 (en) Treatment or prevention of infection
AU2009900969A0 (en) Treatment of infection

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20120817

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAX Request for extension of the european patent (deleted)
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1180215

Country of ref document: HK

A4 Supplementary search report drawn up and despatched

Effective date: 20140311

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 38/48 20060101AFI20140305BHEP

Ipc: C07H 21/04 20060101ALI20140305BHEP

Ipc: C12N 1/21 20060101ALI20140305BHEP

Ipc: C12N 9/64 20060101ALI20140305BHEP

Ipc: C07K 14/61 20060101ALI20140305BHEP

Ipc: C12N 5/10 20060101ALI20140305BHEP

Ipc: A61P 3/08 20060101ALI20140305BHEP

Ipc: C12N 15/63 20060101ALI20140305BHEP

Ipc: C12N 15/62 20060101ALI20140305BHEP

Ipc: A61P 3/10 20060101ALI20140305BHEP

Ipc: C07K 14/46 20060101ALI20140305BHEP

Ipc: A61P 3/04 20060101ALI20140305BHEP

Ipc: A61K 9/14 20060101ALI20140305BHEP

Ipc: A61K 38/27 20060101ALI20140305BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20170524

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS