EP2329257A4 - Devices and methods for the purification, isolation, desalting or buffer/solvent exchange of substances - Google Patents

Devices and methods for the purification, isolation, desalting or buffer/solvent exchange of substances

Info

Publication number
EP2329257A4
EP2329257A4 EP09803694.0A EP09803694A EP2329257A4 EP 2329257 A4 EP2329257 A4 EP 2329257A4 EP 09803694 A EP09803694 A EP 09803694A EP 2329257 A4 EP2329257 A4 EP 2329257A4
Authority
EP
European Patent Office
Prior art keywords
desalting
isolation
purification
substances
buffer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP09803694.0A
Other languages
German (de)
French (fr)
Other versions
EP2329257B1 (en
EP2329257A1 (en
Inventor
Elliott P Dawson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BioVentures Inc
Original Assignee
BioVentures Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BioVentures Inc filed Critical BioVentures Inc
Priority to EP15002788.6A priority Critical patent/EP3006934B1/en
Publication of EP2329257A1 publication Critical patent/EP2329257A1/en
Publication of EP2329257A4 publication Critical patent/EP2329257A4/en
Application granted granted Critical
Publication of EP2329257B1 publication Critical patent/EP2329257B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6091—Cartridges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/22—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B01J20/267—Cross-linked polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/283—Porous sorbents based on silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/291—Gel sorbents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/58—Use in a single column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N2030/381—Flow patterns centrifugal chromatography
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP09803694.0A 2008-08-01 2009-07-31 Devices and methods for the purification, isolation, desalting or buffer/solvent exchange of substances Active EP2329257B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP15002788.6A EP3006934B1 (en) 2008-08-01 2009-07-31 Device for the purification, isolation, desalting or buffer/solvent exchange of substances

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8559108P 2008-08-01 2008-08-01
PCT/US2009/052517 WO2010014970A1 (en) 2008-08-01 2009-07-31 Devices and methods for the purification, isolation, desalting or buffer/solvent exchange of substances

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP15002788.6A Division-Into EP3006934B1 (en) 2008-08-01 2009-07-31 Device for the purification, isolation, desalting or buffer/solvent exchange of substances
EP15002788.6A Division EP3006934B1 (en) 2008-08-01 2009-07-31 Device for the purification, isolation, desalting or buffer/solvent exchange of substances

Publications (3)

Publication Number Publication Date
EP2329257A1 EP2329257A1 (en) 2011-06-08
EP2329257A4 true EP2329257A4 (en) 2014-03-05
EP2329257B1 EP2329257B1 (en) 2018-03-07

Family

ID=41610765

Family Applications (2)

Application Number Title Priority Date Filing Date
EP09803694.0A Active EP2329257B1 (en) 2008-08-01 2009-07-31 Devices and methods for the purification, isolation, desalting or buffer/solvent exchange of substances
EP15002788.6A Active EP3006934B1 (en) 2008-08-01 2009-07-31 Device for the purification, isolation, desalting or buffer/solvent exchange of substances

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP15002788.6A Active EP3006934B1 (en) 2008-08-01 2009-07-31 Device for the purification, isolation, desalting or buffer/solvent exchange of substances

Country Status (5)

Country Link
US (3) US8062533B2 (en)
EP (2) EP2329257B1 (en)
CN (2) CN103657145A (en)
CA (1) CA2730312C (en)
WO (1) WO2010014970A1 (en)

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CN103320319B (en) * 2013-07-05 2015-06-24 博奥生物集团有限公司 Alternative high-throughput electroporation device
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EP3146331B1 (en) * 2014-05-20 2021-02-17 Tecan SP, Inc. Sample extraction apparatus with micro elution bed design
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CN112067731A (en) * 2015-06-10 2020-12-11 恩姆菲舍尔科技公司 Extraction column
CN106317166A (en) * 2015-07-02 2017-01-11 北京中原领先科技有限公司 Device for separating proteins by using high-rate filtration and chromatography mixed mechanism
JP6941168B2 (en) * 2016-10-26 2021-09-29 イー・エム・デイー・ミリポア・コーポレイシヨン Reduction of leachable beta-glucan levels from cellulose-containing filter materials
CN107029452B (en) * 2017-03-29 2020-05-19 广西科技大学 Method for removing plane rigid structure substance from sample
GB201706680D0 (en) * 2017-04-27 2017-06-14 Ge Healthcare Uk Ltd Device and method for sample isolation
USD852375S1 (en) 2017-10-25 2019-06-25 Wake Forest University Health Sciences Cell collection and centrifuge tube assembly
CN111433350B (en) * 2017-11-30 2023-11-14 烟台澳斯邦生物工程有限公司 Method, system and filtration unit for separating particles from biological samples
CN109142600A (en) * 2018-10-18 2019-01-04 云南中烟工业有限责任公司 A kind of method of 4 kinds of mercapturic acids in measurement smoker urine
CN110127888B (en) * 2019-06-18 2023-12-29 大连地拓环境科技有限公司 Selective permeation drainage system for mine restoration
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Title
See also references of WO2010014970A1 *

Also Published As

Publication number Publication date
US8187476B2 (en) 2012-05-29
WO2010014970A1 (en) 2010-02-04
EP2329257B1 (en) 2018-03-07
EP2329257A1 (en) 2011-06-08
CA2730312C (en) 2016-08-16
EP3006934B1 (en) 2017-02-01
EP3006934A3 (en) 2016-06-08
EP3006934A2 (en) 2016-04-13
US8562840B2 (en) 2013-10-22
US20120214974A1 (en) 2012-08-23
CN102132156A (en) 2011-07-20
CN102132156B (en) 2014-11-26
US20100216220A1 (en) 2010-08-26
CA2730312A1 (en) 2010-02-04
CN103657145A (en) 2014-03-26
US8062533B2 (en) 2011-11-22
US20120031845A1 (en) 2012-02-09

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