EP1948270A1 - Commande de sequence d'auto-injecteur permettant un changement de recipient - Google Patents

Commande de sequence d'auto-injecteur permettant un changement de recipient

Info

Publication number
EP1948270A1
EP1948270A1 EP06804838A EP06804838A EP1948270A1 EP 1948270 A1 EP1948270 A1 EP 1948270A1 EP 06804838 A EP06804838 A EP 06804838A EP 06804838 A EP06804838 A EP 06804838A EP 1948270 A1 EP1948270 A1 EP 1948270A1
Authority
EP
European Patent Office
Prior art keywords
locking
mechanism holder
injection device
output member
blocking
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06804838A
Other languages
German (de)
English (en)
Inventor
Edgar Hommann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tecpharma Licensing AG
Original Assignee
Tecpharma Licensing AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecpharma Licensing AG filed Critical Tecpharma Licensing AG
Publication of EP1948270A1 publication Critical patent/EP1948270A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A61M2005/208—Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin

Definitions

  • the invention relates to an injection device for the administration of an injectable product, such as a liquid medicament such as insulin, heparin, a growth hormone or an osteoporosis preparation.
  • an injectable product such as a liquid medicament such as insulin, heparin, a growth hormone or an osteoporosis preparation.
  • the injection device may in particular be an injection pen.
  • an injection device which has a mechanical sequence control.
  • the injection process includes a puncture sequence and a dispensing sequence.
  • a propulsion structure In the piercing sequence, a propulsion structure is moved in the piercing direction so that a needle pierces the device into a body tissue.
  • the Aus thoroughlysequenz is started after completion of the Einstechsequenz, wherein a piston rod is driven in the discharge direction and drives a piston in an ampoule, which spills the product through the pierced needle into the body tissue.
  • Such an injection device is particularly preferably an auto-injector.
  • the administration of a medicament may, for example, be an insertion sequence in which. a needle is inserted into a body tissue and a Aus thoroughlysequenz, in which the Drug dispensing is included.
  • the Aus thoroughlysequenz and Einstechsequenz can be safely separated from each other so that the Aus thoroughlysequenz can only be done after the successful Einstechsequenz.
  • the device may comprise a housing which comprises, for example, two housing parts which are detachably or non-detachably connectable to each other. For this purpose, inter alia, a screw, bayonet, or snap lock in question.
  • a mechanical sequencer can be accommodated in a proximal housing part and a product container in a distal housing part.
  • proximal is meant the side opposite the needle and “distal” is understood to mean the side of the in particular elongate injection device lying on the needle.
  • the product container in particular an ampoule, can be exchangeably inserted into the distal housing part or can be formed directly from the distal housing part.
  • the injection device in particular the proximal housing part comprises a mechanism holder, which can be immovably or fixedly connected to the housing.
  • the mechanism holder can be used as a separate part in the housing and be connected axially and rotationally fixed to the housing.
  • the mechanism holder may alternatively be integral with the housing.
  • the mechanism holder is sleeve-shaped and can support a feed element, which is movable relative to the mechanism holder along a longitudinal axis of the injection device.
  • the advancing element may be sleeve-shaped and slide with its outer circumferential surface along the inner circumferential surface of the mechanism holder along.
  • the feed element for movement relative to the mechanism holder by a resilient element in particular a helical or helical fields are driven when the feed element is released for movement relative to the mechanism holder.
  • the elasticity element can be supported on the mechanism holder and on the feed element, wherein the pressure-loadable or loaded spring generates the driving force for the feed element.
  • the spring can surround the feed element over a certain length.
  • the spring may be at least partially received in an annular gap formed by the feed element and the mechanism holder is formed.
  • the advancing element may have at its distal end an annular flange on which the elastic element can be supported.
  • the advancing member may be locked for movement relative to the mechanism holder of at least one locking member coupled to the advancing member when the locking member engages the mechanism holder.
  • the blocking element may be coupled to the feed element in such a way that, relative to the mechanism holder, it can only perform movement in an approximately radial direction with respect to the longitudinal axis and, in particular, no substantial movements in the axial direction.
  • the blocking element can be a ball which can be moved radially back and forth in a radially extending opening of the feed element.
  • the blocking element is cam-shaped and connected via an arm resiliently with the advancing element. Locking element, arm and feed element are advantageous in one piece.
  • the mechanism holder can each have a locking groove for the at least one blocking element, into which the at least one blocking element can engage.
  • the mechanism holder has an annular locking groove into which the at least one blocking element can engage.
  • the blocking element may for example be designed such that it can be moved against the Einstechtreu the needle out of engagement with the locking groove upon movement or exertion of pressure on the advancing element.
  • the blocking element for example, have a surface which can slide on an edge of the locking groove and move the blocking element out of engagement.
  • the blocking element can also be moved out of engagement with the locking groove via the force of a spring, in particular via the resilient arrangement of the blocking element on an arm.
  • a locking element which is movable along the longitudinal axis of the injection device relative to the advancing element, wherein the locking element in a position in front of the at least one blocking element blocks movement of the locking element out of engagement with the mechanism holder.
  • the locking element crosses the direction of movement with which the locking element would move out of the locking groove, the engagement of the locking element in the Mechanic holder, for example, regardless of a size of the force applied to the feed element force secured.
  • the blocking element is in particular between a Ve ⁇ iegelungsabexcellent of the locking element and the groove bottom of the locking groove.
  • the locking element can be mounted displaceably by the feed element.
  • the advancing element may have at least one groove, preferably a plurality of grooves, which extend along the longitudinal axis and in which engages the locking element, wherein the locking element can slide in the grooves along.
  • the grooves can be arranged in the wall of the sleeve-shaped feed element, for example.
  • a stop element may be formed by the feed element.
  • the locking element can slide along the stop element, wherein the locking element engages around the stop element, in particular with its locking sections.
  • the locking element may for example be U-shaped and engage around the stop element with its legs, wherein the legs can slide in the guide grooves of the feed element.
  • the legs may taper in the direction of the blocking element direction, whereby a simpler engaging behind the locking element is made possible when the locking element is engaged in the locking groove of the mechanism holder.
  • the portion of the locking element, with which the locking element is received in the grooves may have a greater distance from the longitudinal axis of the device, as the locking portion.
  • the locking portion with the radially away from the longitudinal axis facing surface, in particular the surface which holds the at least one locking element in the locking groove be approximately parallel to the longitudinal axis.
  • the sealing portion and the portion with which the locking member is received in the grooves may be connected by the tapered portion, for example.
  • the locking element of a resilient means in particular a spring can be driven, which is supported on a feed element fixed element and the locking element.
  • a corresponding spring may for example be a helical spring or a combined helical and spiral spring or a leaf spring.
  • the feed element fixed element can form the spring.
  • the spring may be biased to pressure or, whereby a force on the Locking element acts in a direction, in particular in the distal direction, which tries to push the locking portion in front of the locking element.
  • the locking element is in an axial stop with the advancing element, in particular with a stop element or the blocking element, when the movement of the blocking element out of engagement with the mechanism holder is blocked by the locking element.
  • the tapered portion may be present on the blocking element, in particular on a gear surface formed thereon.
  • the section connecting the limbs of the locking section can come into abutment with the stop element of the advancing element.
  • an output member is provided, which can be moved along the longitudinal axis relative to the feed element in particular when the blocking element engages in the mechanism holder.
  • the output member may be sleeve-shaped and slide on the feed element, in particular within the feed element along. Between the inner peripheral surface of the feed element and the outer peripheral surface of the output member may be an annular gap.
  • the output member may, for example, at a proximal end have a projecting from the longitudinal axis in approximately radial direction collar, which may be in an axial stop with the blocking element of the feed element, so that a movement of the output member in the discharge direction is blocked in particular when the Locking element is disengaged from the locking groove.
  • the collar preferably protrudes radially from the outer peripheral surface of the output member with a dimension which is smaller than the radial width of the annular groove between the output member and the feed element.
  • the locking member may prevent the movement of at least one of the output member and locking member along the longitudinal axis relative to each other or to the feed element, when the locking element is not in engagement with the mechanism holder.
  • the force can be generated, for example, by an elastic element, in particular a spring, which can be or be biased under pressure.
  • a coil spring is suitable.
  • the elastic element is preferably within the sleeve-shaped output member added.
  • the elasticity or spring constant of the elasticity agent, which can drive the advancing element is greater than the elasticity or elasticity. Spring constant of the elasticity agent, which can drive the output member.
  • the use of a locking element is particularly advantageous when the device is retightened after an injection.
  • the elastic element for driving the output member can be supported in particular on the output member and on the feed element, in particular on the stop element.
  • the driven member is in direct abutment with the locking member and the locking member in direct abutment with the driven member so that I can locate the driven member between the locking member and the locking member when the locking member is not in engagement with the mechanism holder.
  • the blocking element may have a gear surface, which is inclined towards the longitudinal axis of the injection device, so that a longitudinal movement, in particular in the distal direction of at least one driven element and locking element, can move the at least one blocking element radially into engagement with the locking groove of the mechanism holder Locking element axially located approximately at the same height as the locking groove.
  • the gear surface preferably forms the axial stop for the output member and / or the locking element.
  • the locking element can engage in the locking groove against a spring force acting on the locking element against its Einschschulsraum.
  • the collar of the driven member presses the locking member into engagement with the mechanism holder, the advancing locking member sliding in front of the locking member and preventing disengagement of the locking member from engagement with the mechanism holder.
  • the collar of the output member may have a surface which is inclined against the longitudinal axis, in particular with the same degree as the gear surface of the locking element against the longitudinal axis, so that the gear surface and the inclined surface of the collar lie approximately flat on slipping.
  • the at least one locking portion of the Ve ⁇ egelungselements can form the stop for the interaction with the collar or the blocking element.
  • the device may further comprise a switching element which is movable from an initial position via a coupling position to a triggering position along the longitudinal axis. From the starting position to the coupling position of the switching element is arranged, for example, resiliently arranged on the mechanism holder locking member of the switching element into engagement with the feed element, in particular in each case provided for the locking member locking groove.
  • the locking groove may in particular be annular, wherein the at least one locking member engages in the common annular locking groove.
  • the switching element releases the locking element engaging in the advancing element, for example, radially outward, so that the locking member is moved out of engagement with the locking groove, whereby the advancing element is moved in the piercing direction of the needle, for example by a prestressed spring.
  • the feed element takes over the product container in the puncturing direction via, for example, a longitudinally displaceable cage, so that the needle is inserted into a tissue.
  • the at least one blocking element of the advancing element can engage in the mechanism holder as described, whereby in particular the feed element is axially locked, the driven element released for a dispensing movement and / or the locking element is pushed in front of the at least one blocking element of the advancing element.
  • the dispensing movement of the output member is transmitted for example via a piston rod to a piston in the product container, whereby the liquid, for example viscous product is released through the needle into the tissue.
  • the invention further relates to a method for preparing the injection device for a puncture and Aus commonlysequenz. It is assumed that the device is in a state after a successful product distribution.
  • the output member is moved counter to the direction for the product distribution and thereby moves so long relative to the feed element until the output member first the locking element entrains, whereby the blocking element is released for movement and then entrains the feed element.
  • the locking element arranged on the advancing element is moved out of engagement with the mechanism holder and in particular into engagement with the driven member.
  • the blocking element is moved into engagement with the driven member, that the driven member can be moved back only in the dispensing direction by a part of the distance traveled during pushing back against the dispensing direction.
  • the feed element is moved back so far until the locking element of the mechanism holder in the longitudinal direction is approximately at the same height as the locking groove of the feed element, so that the blocking element is moved into the locking groove. In particular, this blocks the movement of the advancing element in the piercing direction.
  • the switching element can be moved back from the release position via the coupling position to the starting position. The device is now ready for a new injection.
  • the invention further relates to a method for controlling the sequence of the injection, wherein the advancing element is moved along the longitudinal axis until at least one locking element coupled to the advancing element engages in a mechanism holder such that movement of the advancing element relative to the mechanism holder is blocked.
  • the locking element is released approximately simultaneously with the intervention of the at least one locking element in the mechanism holder.
  • the locking element is slid along the longitudinal axis to a position in front of the at least one blocking element, so that movement of the at least one blocking element out of engagement with the mechanism holder is blocked.
  • Figure 1 is a sectional view taken along a longitudinal axis of a
  • Figure 2 is a sectional view taken along a longitudinal axis of a
  • Figure 3 is a perpendicular to the sectional view of Figure 2 standing
  • Figure 4 is a perspective view of a switching element and a
  • Figure 5 is a sectional view of a part of an I ⁇ jetechnischsvortechnische in one
  • FIG. 6 shows a sectional view of the part of the injection device from FIG. 5 after product dispensing
  • FIG. 7 shows a sectional view of a switching element and a triggering element in an initial position
  • FIG. 8 shows a sectional view of the switching element and the triggering element
  • Figure 7 in a coupling position
  • Figure 9 is a sectional view of the switching element and the trigger element of the
  • Figures 7 and 8 in a release position and Figure 10 is an exploded view with a feed element, a
  • Locking element and a means of elasticity Locking element and a means of elasticity.
  • FIG. 1 shows an injection device in the form of an auto-injector.
  • the injection device comprises a mechanism with a mechanical sequence control, with which a product container 21 contained in the injection device is first displaced in a distal direction during a puncture sequence, so that the needle 22 attached to the product container 21 is inserted into a body tissue of a patient the puncture sequence is moved distally in the product container 21 during a dispensing sequence of the pistons 20, so that the product contained in the container 21 is dispensed through the needle 22 into the body or body tissue of a patient.
  • FIG. 1 relates in particular also to FIGS. 2 and 3, in which a similar injection device, in particular without a product container 21, is shown.
  • the injection device comprises a distal housing part 25 and a proximal housing part 24, which are connected to a detachable connection, in particular a bayonet closure 23.
  • a mechanism holder 5 is received, which is rotatably and axially fixed to the proximal housing part 24 is connected.
  • this is surrounded with its end faces axially between a radially inwardly projecting projection of the housing 24 and a proximal to the housing 24 plugged cap 26.
  • the mechanism holder 5 surrounds a feed element 6, which is displaceable relative to the mechanism holder 5 along the longitudinal axis L of the injection device.
  • the sleeve-shaped feed element 6 can slide with its outer peripheral surface on the inner peripheral surface of the approximately sleeve-shaped mechanism holder 5 along. Between a distal end face of the mechanism holder 5 and a proximal end face of an annular flange arranged at the distal end of the feed element 6, a spring 10, in particular a helical spring 10 is arranged, which in a pressure-biased state, the feed element 6 relative to the mechanism holder 5 in the distal direction acted upon by a feed force.
  • the distal end surface of the annular flange mounted distally on the advancing element 6 can act in a direction along the longitudinal axis L on a cage 17, which is displaceable along the longitudinal axis L in the housing 24, 25.
  • the cage 17 is coupled to the product container 21 so that upon movement of the cage 17 in the distal direction, the product container 21 is also moved in the distal direction, namely in Einstechiques the needle 22.
  • a movement of the piston 20 within the product container 21 is not yet caused.
  • a pressure-biased spring 27 By means of a pressure-biased spring 27, the product container 21 and the cage 17 are pressed in the proximal direction of the injection device.
  • the force of the spring 27 with which the cage 17 is pressed in the proximal direction is smaller than the force of the spring 10 with which the advancing element 6 and the cage 17 can be moved in the distal direction when the advancing element 6 for movement along the longitudinal axis L. is released, so that the product container 21 can be moved with the needle 22 in the distal direction for piercing the needle 22 in the body tissue.
  • a sleeve-shaped output member 9 is arranged, which can be moved for a Aus thoroughlysequenz relative to the feed element 6 along the longitudinal axis L when it is released for axial movement.
  • a radially outwardly projecting collar 92 At the proximal end of the output member 9 is a radially outwardly projecting collar 92.
  • annular groove Between the output member 9 and the feed element 6 is an annular groove whose groove width is greater than the amount that the collar 92 projects radially from the output member 9.
  • the cage 17 engages with a sleeve-shaped section from the distal side into the inner diameter of the advancing element 9, as can best be seen in FIG.
  • the distal end of the output member 9 has an end face 91 which acts as a stop surface and against which a spring 15, in particular a helical spring, can be supported.
  • the pressure-biasable spring 15 is supported at its other end on a distal surface of a stopper member 64 which is formed at a proximal portion of the advancing member 6.
  • the spring 15, which in particular has a greater spring constant than the spring 10, can drive the released output member 9 in the distal direction along the longitudinal axis L.
  • a locking element 7 which is movable relative to the advancing element 6 along the longitudinal axis L is arranged at the proximal end of the advancing element 6.
  • the locking element 7 is, as can be seen in Figure 10, forked and engages around the longitudinal axis L with two locking portions 71.
  • the locking portions 71 are each guided in a groove-shaped guide 67 ( Figure 10), which is formed by the feed element 6.
  • the locking element 7 is also guided by a stop element 64 accommodated between the locking sections 71 and formed by the advancing element 6. Between the proximal End face of the stop element 64 and a distal end face of the locking element
  • a distance d exist by which the locking member 7 is movable in the distal direction.
  • the locking element 7 is acted upon by a spring 8 with a force in the distal direction.
  • the spring 8 is supported on the proximal end of the locking element 7 and on a feed element-fixed element arranged proximally thereof, namely on the retaining web 81.
  • the holding web 81 can be introduced through openings which form a holding web recording 66, transversely to the longitudinal axis L in the advancing member 6 and attached thereto, as an abutment for the spring
  • the spring 8 may be for example a helical or combined helical and spiral spring or a leaf spring.
  • the retaining web 81 may be made of a spring material and have a shape that can act directly on the locking element 7 with a spring force, so that the spring 8 can be omitted because the locking element 7 takes over the task of the spring 8.
  • a movement of the locking element 7 in the distal direction is prevented, in particular by blocking the locking element 7, in particular with its locking sections 71, by a respective gear surface 65 of a locking element 62.
  • the cam-shaped blocking element 62 is arranged on an arm 61 and, for example, integrally connected in a resilient manner to the advancing element 6.
  • the gear surface 65 also serves in the position shown in Figure 5 for blocking the longitudinal movement of the output member 9.
  • the output member 9 is at its collar 92 on the gear surface 65 at.
  • the locking element 7 can be present either directly on the gear surface 65 or on a proximal portion of the collar 92.
  • the blocking element 62 comes after a certain distance, which preferably corresponds approximately to the path by which the product container 21 is moved to pierce, approximately at the same axial height as a locking groove 53 Locking groove 53 is formed by the feed element 6.
  • the locking groove 53 may be a recess or an annular circumferential recess for the locking elements 62.
  • the locking groove 53 and the locking member 62 are at an axially equal height, is due to the spring force of the arms 61 and / or the Spring force of the spring 8 and / or moved due to the spring force of the spring 15 in conjunction with the sliding of the collar 92 and / or the locking element 7 on the gear surface 65 of the locking element 62 radially outwardly into the locking groove 53. This starts the ejection sequence.
  • the collar 92 is then no longer blocked by the gear surface 65, whereby the spring 15 drives the output member 9 in the distal direction and thus the piston 20 for a product distribution.
  • the locking element 7 is released for axial movement, so that the spring 8 displaces the locking element 7 by the distance d (FIG. 5), as a result of which the locking sections 71 slide in front of the blocking elements 62.
  • a movement of the locking member 62 from the locking groove 53 is prevented because the locking portion 71 blocks the movement that would make the locking member 62 in a movement out of the locking groove 53.
  • the movement can be of the • driven member 9 on a path z (figure 4), wherein the sleeve-shaped portion of the cage 17 forms the end stop, or be limited to a distance which the piston can travel in the product container 21 twentieth
  • the dispensing movement of the output member 9 can not take place until the needle 22 has completed its piercing movement. It is further preferred that the puncture sequence can be started only when designed as a needle cover transfer element 2 is pressed sufficiently firmly at the puncture site on the body tissue.
  • the transmission member 2 is displaced relative to the distal housing part 25.
  • a switching element 1 is movably mounted along the longitudinal axis L. As shown in Figures 7 to 9, the switching element 1 is carried along by the movement of the transfer member 2 in the proximal direction. In this case, a proximal end face of the transmission member 2 and a distal end face of the switching element 1 get into a stop.
  • the transmission member 2 is moved against the force of a spring in the proximal direction.
  • the switching element 1 is pressed by a spring 18 in the distal direction.
  • the switching element 1 can be moved against the force of the spring 18 in the proximal direction.
  • the switching element 1 has an annular portion which cooperates as an axial stop for a movement in the distal direction of the switching element 1 with the mechanism holder 5 when the switching element 1 is in its initial position.
  • the switching element 1 has a control surface element 4, which has a control surface 41 which is inclined relative to the longitudinal axis L. As shown in particular in Figure 4, the switching element 1 is forked. At each of the two fork elements is a control surface element 4.
  • a trigger element 3, which is also forked, has at each of its fork elements on a cam 33 which can cooperate with the respective control surface element 4.
  • the trigger element 3 is transversely, in particular, as shown herein, perpendicular to the longitudinal axis L movable.
  • the cams 33 and the control surface elements 4 are each arranged at a distance from a plane which is spanned by the longitudinal axis L and the direction of movement of the triggering element 3.
  • the fork elements of the switching element 1 and the trigger element 3 engage around the longitudinal axis L.
  • FIG. 7 an initial position of the switching element 1 is shown.
  • the triggering element 3 is pressed by a resilient element, in particular a spring (not shown) with the cam 33 against the control surface 41 of the control surface element 4.
  • an actuating element 31 connected to the triggering element 3 assumes a position below or flush with the level of the housing 24, 25, as shown for example in FIG. 6, the position shown in FIG. 6 being only an example.
  • the actuating element 31 can not or can not easily be actuated, for example, with a finger of the user. Actuation of the actuating element 31 in the starting position shown in FIG. 7 or in an intermediate position between the starting position and the coupling position of the switching element 1 does not trigger the sequence control for the injection.
  • the control surface 41 which is inclined towards the longitudinal axis L, slides along the cam 33, as a result of which the triggering element 3 is initially displaced transversely to the longitudinal axis L, so that the actuating element 31 above the level of the housing 25 lifts.
  • the user can, for example, gain access to the actuating element 31 or an optical indication for the readiness of the device for triggering the sequence control, so that he can actuate the triggering element 3 later in the process.
  • a control surface 42 travels along the cam 33 in a further movement of the switching element 1 in the proximal direction, wherein the control surface 42, as shown in this example, runs approximately parallel to the longitudinal axis L, so that upon movement of the control surface 42 along the Cam 33, the trigger element 3 is stationary.
  • the switching element has reached the coupling position shown in Figure 8, the trigger element 3 and the actuator 31 is operable for effective triggering of the flow control.
  • the actuator 31 is pressed transversely to the longitudinal axis L, then the control surface 32 of the trigger member 3 slides on the cam member 4, whereby the switching element 1 is moved by a distance X 3 in the proximal direction, so that it occupies a release position. In the release position, the sequence control of the injection device is set in motion.
  • the mechanism holder 4 has a locking member 52, which is arranged so as to be resilient via an arm 51 and which engages in a latching groove 63 which is located on the outer circumference of the feed element 6. As long as the locking member 52 engages in the locking groove 63, a movement of the feed element 6 is blocked relative to the mechanism holder 5.
  • a holding stage 11 which is formed by the switching element 1, at the axial height with the locking member 52, so that the locking member 52 is held by the holding stage 11 in engagement with the feed element 6 .
  • a release step 12 formed by the switching element 1 is brought to axial height with the locking member 52, which due to the resilient arm 51 and / or due to the transmission effect of the applied with an axial force of the spring 10 Feed element 6 and the geometry of the locking member 52, the locking member 52 is pressed out of engagement with the locking groove 63.
  • the distance from the holding stage 11 to the longitudinal axis L is less than the distance of the release stage 12 to the longitudinal axis L.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un dispositif d'injection, en particulier un auto-injecteur, comprenant a) un support de mécanisme (5), b) un élément d'avance (6) pouvant être déplacé le long d'un axe longitudinal (L) par rapport au support de mécanisme (5), c) un élément à élasticité (10) destiné à entraîner l'élément d'avance (6), d) au moins un élément d'arrêt (62), pouvant être couplé à l'élément d'avance (6) et pouvant s'engager dans le support de mécanisme (5) pour empêcher un mouvement longitudinal de l'élément d'avance (6) par rapport au support de mécanisme (5), et e) un élément de verrouillage (7) pouvant être déplacé le long de l'axe longitudinal (L) par rapport à l'élément d'avance (6) et qui, lorsqu'il se trouve dans une position de blocage devant ledit au moins un élément d'arrêt (62), bloque ledit au moins un élément d'arrêt (62) afin d'éviter que ce dernier se désengage du support de mécanisme (5).
EP06804838A 2005-11-03 2006-10-31 Commande de sequence d'auto-injecteur permettant un changement de recipient Withdrawn EP1948270A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005052460A DE102005052460A1 (de) 2005-11-03 2005-11-03 Autoinjektor - Ablaufsteuerung für Behältniswechsel
PCT/CH2006/000604 WO2007051331A1 (fr) 2005-11-03 2006-10-31 Commande de sequence d'auto-injecteur permettant un changement de recipient

Publications (1)

Publication Number Publication Date
EP1948270A1 true EP1948270A1 (fr) 2008-07-30

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EP06804838A Withdrawn EP1948270A1 (fr) 2005-11-03 2006-10-31 Commande de sequence d'auto-injecteur permettant un changement de recipient

Country Status (7)

Country Link
US (1) US20080262443A1 (fr)
EP (1) EP1948270A1 (fr)
JP (1) JP2009514573A (fr)
CN (1) CN101355978A (fr)
AU (1) AU2006310972B2 (fr)
DE (1) DE102005052460A1 (fr)
WO (1) WO2007051331A1 (fr)

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Also Published As

Publication number Publication date
WO2007051331A1 (fr) 2007-05-10
AU2006310972B2 (en) 2010-08-26
CN101355978A (zh) 2009-01-28
US20080262443A1 (en) 2008-10-23
AU2006310972A1 (en) 2007-05-10
JP2009514573A (ja) 2009-04-09
DE102005052460A1 (de) 2007-05-16

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