EP1701659A1 - Gerät für die verbesserte schockwellen-lithotripsie (swl) mit einem piezoelektrischen ringförmigen (peaa) stosswellengenerator in kombination mit einer primären stosswelle - Google Patents

Gerät für die verbesserte schockwellen-lithotripsie (swl) mit einem piezoelektrischen ringförmigen (peaa) stosswellengenerator in kombination mit einer primären stosswelle

Info

Publication number
EP1701659A1
EP1701659A1 EP03818331A EP03818331A EP1701659A1 EP 1701659 A1 EP1701659 A1 EP 1701659A1 EP 03818331 A EP03818331 A EP 03818331A EP 03818331 A EP03818331 A EP 03818331A EP 1701659 A1 EP1701659 A1 EP 1701659A1
Authority
EP
European Patent Office
Prior art keywords
shock wave
wave source
primary
piezoelectric
primary shock
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP03818331A
Other languages
English (en)
French (fr)
Other versions
EP1701659A4 (de
Inventor
Pei Zhong
Xufeng Xi
Franklin H. Cocks
Glenn M. Preminger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duke University
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Publication of EP1701659A1 publication Critical patent/EP1701659A1/de
Publication of EP1701659A4 publication Critical patent/EP1701659A4/de
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/225—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for for extracorporeal shock wave lithotripsy [ESWL], e.g. by using ultrasonic waves
    • G—PHYSICS
    • G10—MUSICAL INSTRUMENTS; ACOUSTICS
    • G10K—SOUND-PRODUCING DEVICES; METHODS OR DEVICES FOR PROTECTING AGAINST, OR FOR DAMPING, NOISE OR OTHER ACOUSTIC WAVES IN GENERAL; ACOUSTICS NOT OTHERWISE PROVIDED FOR
    • G10K15/00—Acoustics not otherwise provided for
    • G10K15/04—Sound-producing devices
    • G10K15/043—Sound-producing devices producing shock waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B2017/22005—Effects, e.g. on tissue
    • A61B2017/22007—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
    • A61B2017/22008—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing used or promoted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B2017/22027—Features of transducers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B2017/22027—Features of transducers
    • A61B2017/22028—Features of transducers arrays, e.g. phased arrays

Definitions

  • Electromagnetic shock wave generators may also be used such as the apparatus disclosed by Hahn et al. in U.S. Patent No. 4,655,220.
  • piezoelectric Shockwave generators are equally well known to those skilled in the art and may also be used, such as the apparatus disclosed by Wurster et al. in U.S. Patent No. 4,821 ,730.
  • These previously disclosed devices generate a distribution of high-intensity shock waves in a focal volume embracing the target concretions 4. It is well known in the art that the beam diameter of the shock wave pulses in the focal plane and the depth of focus along the shock wave axis are in the range of 2 to 15, and 12 to 120 mm, respectively.
  • DORNIER HM-3 reflector not shown
  • the pressure waveform produced by either the PEAA 120 or EH 110 source individually was measured using a calibrated polyvinylidene difluoride (PVDF) membrane hydrophone 124 (Sonic Industries, Halboro, PA) that had a frequency bandwidth of 20 MHz, a minimal rise time resolution of 11 ns and a sensitivity of 6.8 kPa/mV.
  • PVDF polyvinylidene difluoride
  • the PVDF hydrophone was scanned at 1 - or 2-mm steps, either along or transverse to the shock-wave axis.
  • the output signal of the hydrophone was recorded on a LECROY digital oscilloscope 126 (Model 9314) at 100 MHz sampling rate.

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Multimedia (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Acoustics & Sound (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
EP03818331A 2003-08-14 2003-08-14 Gerät für die verbesserte schockwellen-lithotripsie (swl) mit einem piezoelektrischen ringförmigen (peaa) stosswellengenerator in kombination mit einer primären stosswelle Ceased EP1701659A4 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2003/025305 WO2005018469A1 (en) 2003-08-14 2003-08-14 Apparatus for improved shock-wave lithotripsy (swl) using a piezoelectric annular array (peaa) shock-wave generator in combination with a primary shock wave

Publications (2)

Publication Number Publication Date
EP1701659A1 true EP1701659A1 (de) 2006-09-20
EP1701659A4 EP1701659A4 (de) 2010-04-07

Family

ID=34215308

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03818331A Ceased EP1701659A4 (de) 2003-08-14 2003-08-14 Gerät für die verbesserte schockwellen-lithotripsie (swl) mit einem piezoelektrischen ringförmigen (peaa) stosswellengenerator in kombination mit einer primären stosswelle

Country Status (4)

Country Link
EP (1) EP1701659A4 (de)
AU (1) AU2003262631A1 (de)
DE (1) DE10394286T5 (de)
WO (1) WO2005018469A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8057408B2 (en) 2005-09-22 2011-11-15 The Regents Of The University Of Michigan Pulsed cavitational ultrasound therapy
US10219815B2 (en) 2005-09-22 2019-03-05 The Regents Of The University Of Michigan Histotripsy for thrombolysis
DE102006021049A1 (de) * 2006-05-05 2007-11-08 Siemens Ag Stoßwellenkopf für eine Stoßwellenbehandlungsvorrichtung und Verfahren zur Fragmentierung und zur Kontrolle der Fragmentierung eines in einem Untersuchungsobjekt angeordneten Fragmentierungsobjekts
CA2742193A1 (en) * 2008-10-18 2010-04-22 Gosbert Weth Pulse wave generator
CA2770706C (en) 2009-08-26 2017-06-20 Charles A. Cain Devices and methods for using controlled bubble cloud cavitation in fractionating urinary stones
JP5863654B2 (ja) 2009-08-26 2016-02-16 リージェンツ オブ ザ ユニバーシティー オブ ミシガン 治療および画像処理超音波変換器用のマイクロマニピュレータ制御アーム
EP2608897B1 (de) 2010-08-27 2023-08-02 SOCPRA Sciences et Génie s.e.c. Mechanischer wellengenerator und verfahren dafür
US9144694B2 (en) 2011-08-10 2015-09-29 The Regents Of The University Of Michigan Lesion generation through bone using histotripsy therapy without aberration correction
WO2013166019A1 (en) 2012-04-30 2013-11-07 The Regents Of The University Of Michigan Ultrasound transducer manufacturing using rapid-prototyping method
WO2014055906A1 (en) 2012-10-05 2014-04-10 The Regents Of The University Of Michigan Bubble-induced color doppler feedback during histotripsy
BR112015032926B1 (pt) * 2013-07-03 2022-04-05 Histosonics, Inc. Sistema de terapia de ultrassom
US11432900B2 (en) 2013-07-03 2022-09-06 Histosonics, Inc. Articulating arm limiter for cavitational ultrasound therapy system
WO2015027164A1 (en) 2013-08-22 2015-02-26 The Regents Of The University Of Michigan Histotripsy using very short ultrasound pulses
EP3313517B1 (de) 2015-06-24 2023-06-07 The Regents Of The University Of Michigan System für histotripsietherapie zur behandlung des hirngewebes
US11813484B2 (en) 2018-11-28 2023-11-14 Histosonics, Inc. Histotripsy systems and methods
US11813485B2 (en) 2020-01-28 2023-11-14 The Regents Of The University Of Michigan Systems and methods for histotripsy immunosensitization
CN117340692B (zh) * 2023-12-05 2024-02-20 太原理工大学 金属增材制造零件声磁耦合场辅助液体喷射抛光装置

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888746A (en) * 1987-09-24 1989-12-19 Richard Wolf Gmbh Focussing ultrasound transducer
US5582578A (en) * 1995-08-01 1996-12-10 Duke University Method for the comminution of concretions
US6298264B1 (en) * 1998-08-31 2001-10-02 Duke University Apparatus and method for macromolecule delivery into living cells
US20030093013A1 (en) * 2001-11-09 2003-05-15 Duke University Method and apparatus to reduce tissue injury in shock wave lithotripsy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2643252B1 (fr) * 1989-02-21 1991-06-07 Technomed Int Sa Appareil de destruction selective de cellules incluant les tissus mous et les os a l'interieur du corps d'un etre vivant par implosion de bulles de gaz
US5827204A (en) * 1996-11-26 1998-10-27 Grandia; Willem Medical noninvasive operations using focused modulated high power ultrasound
US6309355B1 (en) * 1998-12-22 2001-10-30 The Regents Of The University Of Michigan Method and assembly for performing ultrasound surgery using cavitation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888746A (en) * 1987-09-24 1989-12-19 Richard Wolf Gmbh Focussing ultrasound transducer
US5582578A (en) * 1995-08-01 1996-12-10 Duke University Method for the comminution of concretions
US6298264B1 (en) * 1998-08-31 2001-10-02 Duke University Apparatus and method for macromolecule delivery into living cells
US20030093013A1 (en) * 2001-11-09 2003-05-15 Duke University Method and apparatus to reduce tissue injury in shock wave lithotripsy

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO2005018469A1 *
XI X ET AL: "Improvement of stone fragmentation during shock-wave lithotripsy using a combined EH/PEAA shock-wave generator-in vitro experiments" ULTRASOUND IN MEDICINE AND BIOLOGY, NEW YORK, NY, US, vol. 26, no. 3, 1 March 2000 (2000-03-01), pages 457-467, XP004295535 ISSN: 0301-5629 *

Also Published As

Publication number Publication date
EP1701659A4 (de) 2010-04-07
WO2005018469A1 (en) 2005-03-03
AU2003262631A1 (en) 2005-03-10
DE10394286T5 (de) 2006-06-29

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