EP1633193A1 - Agents destines a lutter contre les micro-organismes, renfermant de l'huile de patchouli, de l'alcool de patchouli et/ou leurs derives - Google Patents

Agents destines a lutter contre les micro-organismes, renfermant de l'huile de patchouli, de l'alcool de patchouli et/ou leurs derives

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Publication number
EP1633193A1
EP1633193A1 EP04736635A EP04736635A EP1633193A1 EP 1633193 A1 EP1633193 A1 EP 1633193A1 EP 04736635 A EP04736635 A EP 04736635A EP 04736635 A EP04736635 A EP 04736635A EP 1633193 A1 EP1633193 A1 EP 1633193A1
Authority
EP
European Patent Office
Prior art keywords
aspergillus
acid
agents
derivatives
patchouli
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP04736635A
Other languages
German (de)
English (en)
Other versions
EP1633193B1 (fr
Inventor
Mirko Weide
Anja SCHLÖSSER
Dirk Bockmühl
Andreas Bolte
Roland Breves
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henkel AG and Co KGaA
Original Assignee
Henkel AG and Co KGaA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2003127134 external-priority patent/DE10327134A1/de
Priority claimed from DE10327138A external-priority patent/DE10327138A1/de
Application filed by Henkel AG and Co KGaA filed Critical Henkel AG and Co KGaA
Publication of EP1633193A1 publication Critical patent/EP1633193A1/fr
Application granted granted Critical
Publication of EP1633193B1 publication Critical patent/EP1633193B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08—Magnoliopsida [dicotyledons]
    • A01N65/22—Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22—Organic compounds
    • C11D7/24—Hydrocarbons
    • C11D7/245—Hydrocarbons cyclic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/06—Oxygen or sulfur directly attached to a cycloaliphatic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A61Q11/02—Preparations for deodorising, bleaching or disinfecting dentures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B24/00—Use of organic materials as active ingredients for mortars, concrete or artificial stone, e.g. plasticisers
    • C04B24/02—Alcohols; Phenols; Ethers
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B24/00—Use of organic materials as active ingredients for mortars, concrete or artificial stone, e.g. plasticisers
    • C04B24/08—Fats; Fatty oils; Ester type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B40/00—Processes, in general, for influencing or modifying the properties of mortars, concrete or artificial stone compositions, e.g. their setting or hardening ability
    • C04B40/0028—Aspects relating to the mixing step of the mortar preparation
    • C04B40/0039—Premixtures of ingredients
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
    • C09D5/14—Paints containing biocides, e.g. fungicides, insecticides or pesticides
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K3/00—Materials not provided for elsewhere
    • C09K3/10—Materials in mouldable or extrudable form for sealing or packing joints or covers
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22—Organic compounds
    • C11D7/26—Organic compounds containing oxygen
    • C11D7/261—Alcohols; Phenols
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22—Organic compounds
    • C11D7/26—Organic compounds containing oxygen
    • C11D7/261—Alcohols; Phenols
    • C11D7/262—Alcohols; Phenols fatty or with at least 8 carbon atoms in the alkyl or alkenyl chain
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22—Organic compounds
    • C11D7/26—Organic compounds containing oxygen
    • C11D7/264—Aldehydes; Ketones; Acetals or ketals
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22—Organic compounds
    • C11D7/32—Organic compounds containing nitrogen
    • C11D7/3281—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C14—SKINS; HIDES; PELTS; LEATHER
    • C14C—CHEMICAL TREATMENT OF HIDES, SKINS OR LEATHER, e.g. TANNING, IMPREGNATING, FINISHING; APPARATUS THEREFOR; COMPOSITIONS FOR TANNING
    • C14C9/00—Impregnating leather for preserving, waterproofing, making resistant to heat or similar purposes
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2103/00—Function or property of ingredients for mortars, concrete or artificial stone
    • C04B2103/60—Agents for protection against chemical, physical or biological attack
    • C04B2103/67—Biocides
    • C04B2103/69—Fungicides
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
    • C04B2111/00474—Uses not provided for elsewhere in C04B2111/00
    • C04B2111/00663—Uses not provided for elsewhere in C04B2111/00 as filling material for cavities or the like
    • C04B2111/00672—Pointing or jointing materials
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2200/00—Chemical nature of materials in mouldable or extrudable form for sealing or packing joints or covers
    • C09K2200/04—Non-macromolecular organic compounds
    • C09K2200/0429—Alcohols, phenols, ethers
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2200/00—Chemical nature of materials in mouldable or extrudable form for sealing or packing joints or covers
    • C09K2200/04—Non-macromolecular organic compounds
    • C09K2200/0447—Fats, fatty oils, higher fatty acids or derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00—Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/20—Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
    • Y10T442/2549—Coating or impregnation is chemically inert or of stated nonreactance
    • Y10T442/2566—Organic solvent resistant [e.g., dry cleaning fluid, etc.]

Definitions

  • the invention relates to compositions containing patchouli oil, patchouli alcohol and / or its derivatives and their use for inhibiting the asexual reproduction of fungi and for reducing the adhesion of microorganisms to surfaces, and filter media containing these substances, adhesives, building materials and / or construction aids, in particular sealing compounds and adhesives , Textiles, furs, paper, skins or leather, but also detergents, cleaning agents, rinsing agents, textile treatment agents, hand washing agents, hand dishwashing detergents, machine dishwashing detergents, building materials and building aids, cosmetic and / or pharmaceutical agents, as well as mouth, tooth and denture care agents and agents for equipment of building materials and / or auxiliary materials, textiles, furs, paper, furs or leather.
  • adhesion of microorganisms to surfaces is undesirable, especially in the case of pathogenic microorganisms.
  • Adherent microorganisms often lead to infections or reinfection in humans, animals and plants.
  • Sensitive textiles such as B. silk or microfiber, processed into garments that can only be washed at 30 or 40 0 C. This does not kill fungi, such as the human pathogenic Candida albicans. Especially after a fungal infection, such fungi adhering to clothing and not killed can lead to reinfection.
  • dentition bearers often develop oral candidiasis (thrush). Fungal cells adhering to the surface of the prosthesis can colonize the mucous membranes on contact, which are often damaged by pressure points.
  • biocides or biostatics used in detergents and cleaning agents pollute the wastewater and thus also impair the function of the microbial treatment stages in the treatment plants.
  • selection pressure on the microorganisms to form resistance is greatly increased, so that after some time new antimicrobial substances have to be found which act against these microorganisms which have become resistant.
  • Fungi in particular mold, occur, for example, in the household at various places, for example in the kitchen or in damp rooms, such as e.g. in the bathroom. Molds cause considerable problems because the spores they release into the air are often allergy-causing. Combating such fungi with biocidal agents is associated with an increased risk of developing resistance, so that after some time new antimicrobial substances have to be found that act against these microorganisms that have become resistant. In addition, biocides are not always ecologically and toxicologically safe. The undesirable effects of the spread of molds include discoloration (for example on walls, joint sealants and other bathroom surfaces), which are caused by pigmented spores.
  • the object of the invention is therefore to overcome the disadvantages of the prior art and to specifically avoid the negative effects of sporulating fungi and to remove microorganisms from surfaces without one to generate increased pressure on the microorganisms to form resistance and without polluting these surfaces or the waste water with biocidal and / or biostatic active substances or with active substances in biocidal or biostatic concentrations.
  • Microorganisms are to be understood in particular as bacteria, fungi and viruses and algae. This includes bacterial endospores or exospores as well as spores, which serve as reproductive structures in fungi.
  • reducing the adherence is meant a significant reduction in the number of adhering microorganism cells. Ideally, the adherence is completely prevented. The adherence of microorganism cells is preferably reduced or essentially prevented entirely.
  • the term asexual reproduction includes, in particular, spore formation, budding and fragmentation.
  • the present invention therefore relates to compositions comprising patchouli oil, patchouli alcohol and / or derivatives thereof and the use thereof Inhibiting the asexual reproduction of fungi and reducing the adherence of microorganisms to surfaces.
  • patchouli oil is obtained from the plant parts of the patchouli shrub (Pogostemon cablin or patchouli and P. heyneaus from the family of the Laminaceae or Labiatae). According to the invention, it is possible to obtain the patchouli oil by extraction with solvents or their mixtures, preferably organic solvents, in particular with hydrocarbons (for example CAS 84238-39-1; CAS 90082-40-9).
  • solvents or their mixtures preferably organic solvents, in particular with hydrocarbons (for example CAS 84238-39-1; CAS 90082-40-9).
  • Patchouli oil (in particular CAS 8014-09-3) obtained from the leaves by means of steam distillation is particularly preferred. Fermented leaves of the patchouli shrub are preferably used for the extraction.
  • the patchouli oil is particularly well absorbed on surfaces, so that finishing, particularly of textiles, but also of plastic and metal surfaces, can be carried out particularly effectively and easily.
  • the patchouli oil obtained by steam distillation of the fermented leaves contains patchouli alcohol, patchoulenol, patchoulenon, norpatchoulenol, nortetrapatchoulol, Seychelles, ⁇ -patchoules, ß-patchoules, ⁇ -guaajes and ⁇ -Bulnese.
  • patchouli alcohol derivatives also include patchoulenol, norpatchoulenol and Seychelles.
  • the growth of the microorganisms is advantageously neither inhibited nor killed, only the adhesion of microorganisms to surfaces and the asexual reproduction inhibited or suppressed by fungi.
  • the selection pressure for the development of resistance is therefore low.
  • patchouli oil and patchouli alcohol are toxicologically safe, as far as is known at the present time, so that the use of biocidal substances which are significantly more harmful to humans, animals and the environment can be dispensed with or at least the use can be reduced.
  • the use of patchouli oil or patchouli alcohol at the same concentration is more advantageous from the point of view of toxicological compatibility.
  • Another advantage of the invention is that, compared to biocides or biostatics, these substances are effective even in low final concentrations and therefore hardly any side effects have to be feared.
  • the inhibition of asexual reproduction and the reduction in adherence due to the reduced contact of the human body with the microorganism cells, for example the respiratory tract with mold spores, can also lead to a reduction in the allergy-triggering potential, in particular within living spaces.
  • patchouli oil, patchouli alcohol and / or its derivatives are used in such final concentrations that they do not have a biocidal or biostatic, in particular fungicidal or fungistatic.
  • a particular advantage of this embodiment is that the risk of developing resistance to the substances used is relatively low, since the microorganisms are neither killed nor inhibited in their growth.
  • the concentrations at which growth is not yet inhibited, as well as the minimum inhibitory concentrations themselves, can easily be determined in a manner known to those skilled in the art.
  • patchouli oil, patchouli alcohol and / or its derivatives are present in an amount of 0.000001 to 3% by weight.
  • a particular advantage of this embodiment is that only small concentrations of these active ingredients have to be present, so that the asexual multiplication of fungi, in particular sporulation, is inhibited or the adherence of the microorganisms to surfaces is reduced or essentially completely prevented.
  • the substances are preferably contained in 0.00001 to 1% by weight and in particular in 0.0001 to 0.5% by weight. Ranges between 0.0001 and 0.1% by weight are particularly preferred.
  • concentration ranges between 0.0001 and 0.05% by weight are particularly preferred.
  • amounts between 0.0001 and 1.0% by weight are particularly preferred.
  • Dilution factor ratio of detergent concentrate: water
  • the dilution ratio for detergents is often between 1:60 and 1:100, for example 1:80.
  • concentrations would be from 0.001 to 1.5
  • % By weight in particular from 0.01 to 0.8% by weight, is suitable.
  • microorganisms are preferably bacteria and fungi.
  • the yeasts, molds and the keratinophilic fungi are particularly preferred.
  • the active ingredients patchouli oil, patchouli alcohol and / or its derivatives which can be used according to the invention are particularly suitable for use (in particular for inhibiting the asexual propagation of fungi) against those fungi which are in the master lists "DSMZ - List of Filamentous Fungi” and “DSMZ - List of Yeasts "of the DSMZ (German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig) are listed. The lists can be viewed on the Internet at (http://www.dsmz.de/species/fungi.htm) or (http://www.dsmz.de/species/veasts.htm).
  • molds are to be understood as those fungi which have their habitat in the soil, on food and / or feed or in concentrated nutrient solutions, form a typical mycelium and obtain their nutrients from organic substances which they decompose as a result (saprobionic or saprophytic way of life). Furthermore, they reproduce predominantly asexually through spores (in particular sporangiospores or conidia) and form, if at all, only very small sexual reproductive organs.
  • species from the classes Ascomycota, Basidiomycota, Deuteromycota and Zygomycota in particular all species of the genera Aspergillus, Penicillium, Cladosporium and Mucor, as well as Stachybotrys, Phoma, Alternaria, Aureobasidium, Ulocladium, Epicoccum, Paemilomis, Stomilomisis, Stodermylis , Wallemia, Botrytis, Verticillium and Chaetonium.
  • the Ascomycota include in particular all species of the genera Aspergillus, Penicillium and Cladosporium. These fungi form spores that have a strong allergy-causing potential when they come into contact with the skin or the respiratory tract.
  • Cryptococcus neoformans belongs to the Basidiomycota counting.
  • Deuteromycota includes all genera known as molds, especially those that, due to the lack of a sexual stage, are not assigned to the Ascomycota, Basidiomycota or Zygomycota classes.
  • Patchouli oil, patchouli alcohol and / or its derivatives are particularly preferred for inhibiting asexual reproduction, in particular sporulation, of all species of the genus Aspergillus, and for reducing their adhesion to surfaces, very particularly preferably for species selected from Aspergillus aculeatus, Aspergillus albus, Aspergillus alliaceus, Aspergillus asperescens, Aspergillus awamori, Aspergillus candidus, Aspergillus carbonarius, Aspergillus carneus, Aspergillus chevalieri, Aspergillus chevalieri var.
  • the sporulation of Aspergillus flavus and Apsergillus nidulans is particularly preferably inhibited and their adherence is reduced or essentially prevented.
  • patchouli oil, patchouli alcohol and / or its derivatives are very particularly preferably used to inhibit spore formation in species of the genus Aspergillus, which are selected from Aspergillus flavus and Aspergillus nidulans.
  • the patchouli oil, patchouli alcohol and / or its derivatives are used to inhibit the Spore formation used.
  • Spore formation means both the formation of propagation forms, for example conidia, gonitocysts, sporangiospores, arthrospores, blastospores and their associated organs (for example conidiophores), as well as permanent forms (for example chlamydospores).
  • patchouli oil, patchouli alcohol and / or its derivatives to inhibit spore formation has the further advantage that the concentration required to inhibit sporulation is surprisingly significantly lower than that of other sesquiterpenes, for example Famesol. A comparable effect can also be achieved with a lower concentration of active ingredient.
  • patchouli oil and patchouli alcohol have a woody fragrance, which gives the corresponding substances according to the invention a pleasant fragrance and can possibly make additional perfume addition unnecessary.
  • yeasts are unicellular fungi which multiply predominantly by sprouting. Yeasts do not represent an independent taxonomic category in the system of fungi. Most of the yeasts are systematically classified as endomycetes. In addition, sprout cell stages occur in various other fungi in the development cycle or under certain environmental conditions, which are referred to as yeast stages. Such unicellular, yeast-like sprouting growth forms occur with the Ascomycetes, but also with the Zygomycetes, Basidomycetes and Deuteromycetes. According to the invention, all of these growth forms are also to be understood as yeasts.
  • patchouli oil, patchouli alcohol and / or its derivatives reduces the adhesion of fungi which are pathogenic to humans and / or inhibits their asexual reproduction.
  • fungi which are pathogenic to humans and / or inhibits their asexual reproduction.
  • human-pathogenic species from the classes Ascomycota, Basidiomycota, Deuteromycota and Zygomycota, in particular the human-pathogenic forms of Candida.
  • the human pathogenic Candida species also colonize the skin and mucous membranes in healthy people. If the fungal cells multiply rapidly, e.g. B. after damage to the bacterial mucosal flora by antibiotics, but they cause local inflammation, which is also referred to as thrush. In particular, these occur in the mouth and genital area (so-called oral or vaginal thrush). Skin and diaper thrush are also known. The mucous membrane is red, lesions appear, a white coating and itching.
  • the adhesion of fungi of the Candida species is reduced (hereinafter abbreviated to C.), such as. E.g .: C. aaseri, C. actiscondensi, C. acutus, C. agrestis, C. albicans, C. amapae, C. anatomiae, C. ancudensis, C. antarctica, C. antillancae, C. apicola, C. apis , C. aquaetextoris, C. aquatica, C. atlantica, C. atmaerica, C. auringiensis, C. azyma, C. beechii, C. benhamii, C.
  • C. such as. E.g .: C. aaseri, C. actiscondensi, C. acutus, C. agrestis, C. albicans, C. amapae, C. anatomiae, C. ancuden
  • the attachment of fungi of the species Rhodotorula spp., Cryptococcus spp., Exophilia spp. , Hormoconis spp. reduced.
  • the use according to the invention preferably reduces the adhesion of the medically relevant forms of Candida, for example: C. albicans, C. boidinii, C. catenulata, C. cifieri, C. dubliniensis, C. glabrata, C. guilliermondii, C. haemulonii, C. kefyr, C. krusei, C. lipolytica, C. lusitaniae, C. norvegensis, C. parapsilosis, C. p ⁇ lcherrima, C. rugosa, C. tropicalis, C. utilis, C. viswanathii. C. albicans, C.
  • Candida for example: C. albicans, C. boidinii, C. catenulata, C. cifieri, C. dubliniensis, C. glabrata, C. guilliermondii, C. haemulonii, C. kef
  • the mycelial form of Candida is considered to be a human-pathogenic form of the fungus.
  • Keratinophilic fungi are to be understood as those skin and / or hair fungi that grow in horny skin and its appendages (in particular hair and / or nails). In particular, this includes dermatophytes and all species of the genus Malassezia. According to the invention, dermatophytes are to be understood in particular to mean all species of the genera Trichophyton, Microsporum and Epidermophyton.
  • the keratinophilic mushroom Malassezia a yeast
  • Malassezia a yeast
  • This organism is also considered to trigger the skin disease pityriasis versicolor. It is therefore particularly advantageous to reduce or substantially prevent the adhesion of Malassezia, in particular the species M. furfur (also known under the name Pityrosporum ovale), M. pachydermatis, M. sympodialis and / or M. globosa.
  • the keratinophilic fungi are selected from Trichophyton mentagrophytes, T. rubrum, T. asteroides, T. concentrium, T. equinum, T. meginii, T. gallinae, T. tonsurans, T. schoenleinii, T. terrestre, T. verrucosum, T. violaceum, Microsporum canis, Microsporum audounii, M. gypseum, Epidermophyton flossocum, Malassezia furfur, M. sympodialis, M. globosa and M. pachydermatis.
  • the use of patchouli oil, patchouli alcohol and / or its derivatives prevents the adhesion of Dermatophytes diminished on surfaces.
  • the dermatophytes are selected from Trichophyton mentagrophytes, T. rubrum, T. asteroides, T. concentrium, T. equinum, T. meginii, T. gallinae, T. tonsurans, T. schoenleinii, T. terrestre, T. verrucosum, T. violaceum, Microsporum canis, Microsporum audounii, M. gypseum and Epidermophyton flossocum.
  • the use of patchouli oil, patchouli alcohol and / or its derivatives reduces the adhesion of bacteria, e.g. the following gram-negative and gram-positive bacteria, in particular the pathogenic bacteria Propionibacterium acnes, Stapylococcus aureus, streptococcal group A (beta-hemolytic S.), S. pyogenes, Corynebacterium spp. (particularly C. tenuis, C. diphtheriae, C. minutissimum), Micrococcus spp. (especially M. sedentarius), Bacillus anthracis, Neisseria meningitidis, N.
  • bacteria e.g. the following gram-negative and gram-positive bacteria, in particular the pathogenic bacteria Propionibacterium acnes, Stapylococcus aureus, streptococcal group A (beta-hemolytic S.), S. pyogenes, Corynebacterium spp. (particularly
  • Stenotrophomonas spec Stenotrophomonas spec, Xanthomonas spec (campestris), Neisseria spec, Haemophilus spec. as well as all microorganisms that acc. "Paster et al. J. Bac 183, 12, 2001, 3770-3783".
  • patchouli oil, patchouli alcohol and / or its derivatives prevents the attachment of viruses which are pathogenic to humans, animals and / or plants and bacteriophages.
  • Algae are single to multicellular, differently colored, primarily photoautotrophic plants or photoautotrophic bacteria of mostly thallophytic organization, the gametes and spore-forming organs of which are generally unicellular and possibly have envelopes made of sterile cells. Algae are differentiated according to their pigment composition into green, red, blue and brown algae, whereby green and blue algae on facades and building materials are particularly relevant.
  • the relevant representatives of the blue-green algae (Cyanobacteria) are from the genera Anabaena, Anacystis, esp. Anacystis montana, Gloeocapsa, Lyngbia, Nostoc, Oscillatoria, esp.
  • Chlorophyla Choricystis
  • Chlamydomonas Chlorococcum
  • Stichcoccus esp. Stichcoccus bacillaris
  • Ulothrix and Trentepholia esp. Trentepholia odorata.
  • the adherence of algae to surfaces, particularly in very damp rooms and aquariums, but also to surfaces that are exposed to the weather, such as building materials, including in particular sealants or seals can be achieved by using patchchouli oil, patchouli alcohol and / or whose derivatives are prevented.
  • the adherence of microorganisms to the surfaces which frequently come into contact with the human body is reduced or essentially completely prevented.
  • Abiotic, technical (or technically manufactured) surfaces are meant in particular. In the sense of this particular embodiment, human tissue is therefore not to be understood as being included.
  • the asexual multiplication and / or the adhesion of microorganisms on such surfaces as textiles, ceramics, metals and / or plastics or in or on filter media, building materials, construction aids, furs, paper, skins, leather is inhibited or reduced.
  • the present invention furthermore relates to detergents, cleaning agents, rinsing agents, hand washing agents, hand dishwashing detergents, machine dishwashing detergents, cosmetic and / or pharmaceutical agents and agents for finishing surfaces and / or packaging, in particular those which come into contact with food, filter media, building materials, auxiliary building materials , Textiles, furs, paper, skins or leather, containing patchouli oil, patchouli alcohol and / or its derivatives, in particular to inhibit the asexual reproduction of fungi and to reduce the adhesion of microorganisms to surfaces.
  • Further objects of the present invention are filter media, building materials, auxiliary building materials, textiles, furs, paper, furs or leather which contain patchouli oil, patchouli alcohol and / or its derivatives and / or have been equipped with an agent according to the invention.
  • patchouli oil, patchouli alcohol and / or its derivatives are added to detergents and / or cleaning agents or for oral care or denture cleaning products.
  • the modern textile fibers which cannot be washed with heavy-duty detergents or at high temperatures, cannot be completely freed from microorganism build-up by conventional mild detergents or washing temperatures at 30 or 40 ° C.
  • One advantage of using such additives in detergents and cleaning agents is that, despite the low wastewater pollution and the low risk of developing resistance, clothing can be freed from the adhesion of microorganisms.
  • Dental prostheses especially dentures, can be cleaned from the microorganism adhesion effectively, simply and without stressing the treated surface with strongly biocidal, possibly conditionally toxic substances by the use of such substances in oral, tooth and / or denture care products.
  • Patchouli oil, patchouli alcohol and / or its derivatives are particularly suitable for oral, dental and / or dental prosthesis care.
  • Another object of the invention are washing and / or cleaning agents containing 0.000001 to 3% by weight of patchouli oil, patchouli alcohol and / or its derivatives. Concentrations of 0.00001 to 1.0% by weight and in particular 0.0001 to 0.5% by weight are particularly preferred.
  • the washing and cleaning agents very particularly preferably contain 0.0001 to 0.05% by weight, in particular up to 0.01% by weight, of these substances.
  • washing and cleaning agents can contain relatively small amounts of the substances without polluting the waste water. Since they are used in concentrated form and on the corresponding effective concentrations in the Dilute wash liquor, the active ingredients must be used in a correspondingly higher concentration. Dilutions of the washing and cleaning agents with water between 1: 40 and 1: 200 are common.
  • such substances can also be used for cleaning agents which are used to clean hard surfaces, such as floors, tiles, tiles, plastics and other hard surfaces in the household, in particular in damp rooms (for example bathrooms), in public sanitary facilities, in swimming pools, saunas , Sports facilities or in medical or massage practices.
  • cleaning agents which are used to clean hard surfaces, such as floors, tiles, tiles, plastics and other hard surfaces in the household, in particular in damp rooms (for example bathrooms), in public sanitary facilities, in swimming pools, saunas , Sports facilities or in medical or massage practices.
  • damp rooms for example bathrooms
  • shower curtains and other bath textiles as well as plastics can also be protected from mold (-spore) -related discoloration.
  • pathogenic microorganisms especially fungi and bacteria
  • Salmonelle spec especially Brachybacterium spec
  • Actinobacteria especially Brachybacterium spec
  • alpha-Proteobacteria especially Agrobacterium spec
  • beta-Proteobacteria especially Ntrosomonas spec
  • Aquabacterium spec especially Hydrogenophaga
  • gamma-Proteobacteria especially Stenotrophomonas spec., Xanth (campestris)
  • detergents and cleaning agents in the context of the invention include preparations in solid form (particles, powder, etc.), semi-solid form (pastes, etc.), liquid form (solutions, emulsions, suspensions, gels, etc.) and gas-like form ( Aerosols etc.) understood, which contain one or more surfactants with a view to an advantageous effect, usually in addition to other components which are customary for the respective application.
  • surfactant-containing preparations are surfactant-containing detergent preparations, surfactant-containing cleaning agents for hard surfaces, or surfactant-containing finishing agents, which can each be solid or liquid, but can also be in a form which comprises solid and liquid components or partial amounts of the components side by side.
  • the detergents and cleaning agents can usually contain ingredients, such as anionic, nonionic, cationic and amphoteric surfactants, inorganic and organic builder substances, special polymers (for example those with cobuilder properties), foam inhibitors, dyes and, if appropriate, additional fragrances (perfumes), bleaches (such as for example peroxo bleach and chlorine bleach), bleach activators, bleach stabilizers, bleach catalysts, enzymes and graying inhibitors, without the ingredients being restricted to these substance groups.
  • Important ingredients of these preparations are often also washing aids, for which exemplary and non-limiting optical brighteners, UV protection substances, so-called soil repellents, that is to say polymers which counteract re-soiling of fibers, are understood.
  • the individual substance groups are explained in more detail below. In the event that the preparations are at least partially in the form of moldings, binding and disintegration aids can also be present.
  • Anionic, nonionic, zwitterionic and cationic surfactants can be used as surfactants.
  • Anionic surfactants used are, for example, those of the sulfonate and sulfate type.
  • Suitable surfactants of the sulfonate type are preferably Cg- 13- alkylbenzenesulfonates, olefin sulfonates, ie mixtures of alkene and hydroxyalkanesulfonates and disulfonates, such as those obtained from Ci 2 - 18 monoolefins with a terminal or internal double bond Sulfonation with gaseous sulfur trioxide and subsequent alkaline or acid hydrolysis of the sulfonation products is obtained.
  • alkanesulfonates which are obtained from Ci 2- i 8 alkanes, for example by sulfochlorination or sulfoxidation with subsequent hydrolysis or neutralization.
  • the esters of 2-sulfofatty acids for example the 2-sulfonated methyl esters of hydrogenated coconut, palm kernel or tallow fatty acids, are also suitable.
  • Suitable anionic surfactants are sulfonated fatty acid glycerol esters.
  • Fatty acid glycerol esters are to be understood as meaning the mono-, di- and triesters and their mixtures as obtained in the production by esterification of a monoglycerol with 1 to 3 moles of fatty acid or in the transesterification of triglycerides with 0.3 to 2 moles of glycerol.
  • Preferred sulfonated fatty acid glycerol esters are the sulfonation products of saturated fatty acids having 6 to 22 carbon atoms, for example caproic acid, caprylic acid, capric acid, myristic acid, lauric acid, palmitic acid, stearic acid or behenic acid.
  • the alk (en) yl sulfates are the alkali and in particular the sodium salts of the sulfuric acid semiesters of the Ci 2 -Ci 8 fatty alcohols, for example from coconut fatty alcohol, tallow fatty alcohol, lauryl, myristyl, cetyl or stearyl alcohol or the Cio-C 2 o-oxo alcohols and those half esters of secondary alcohols of these Chain lengths preferred.
  • alk (en) yl sulfates of the chain length mentioned which contain a synthetic, petrochemical-based straight-chain alkyl radical which have a degradation behavior analogous to that of the adequate compounds based on oleochemical raw materials.
  • Ci 2 -Ci 6 alkyl sulfates and C 12 -C 5 alkyl sulfates and Cu-C 15 alkyl sulfates are preferred.
  • 2,3-alkyl sulfates which are produced for example in accordance with US Patent No. 3,234,258 or 5,075,041 and which are commercially obtainable as products of the Shell Oil Company under the name DAN ®, are suitable anionic surfactants.
  • sulfuric acid monoesters of the straight-chain or branched chain ethoxylated with 1 to 6 mol of ethylene oxide such as 2-methyl-branched C 9 . 11 - alcohols containing on average 3.5 mol ethylene oxide (EO) or C 2-18 fatty alcohols containing 1 to 4 EO, are also suitable. Because of their high foaming behavior, they are used in washing and cleaning agents only in relatively small amounts, for example in amounts of 1 to 5% by weight.
  • Suitable anionic surfactants are also the salts of alkylsulfosuccinic acid, which are also referred to as sulfosuccinates or as sulfosuccinic acid esters, and which are monoesters and / or diesters of sulfosuccinic acid with alcohols, preferably fatty alcohols and especially ethoxylated fatty alcohols.
  • Preferred sulfosuccinates contain C ⁇ -fatty alcohol residues or mixtures thereof.
  • Particularly preferred sulfosuccinates contain a fatty alcohol residue, which is derived from ethoxylated fatty alcohols, which in themselves are nonionic surfactants (description see below).
  • sulfosuccinates the fatty alcohol residues of which are derived from ethoxylated fatty alcohols with a narrow homolog distribution, are particularly preferred. It is also possible to use alk (en) ylsuccinic acid with preferably 8 to 18 carbon atoms in the alk (en) yl chain or salts thereof.
  • Soaps are particularly suitable as further anionic surfactants.
  • Saturated fatty acid soaps such as the salts of lauric acid, myristic acid, palmitic acid, stearic acid, hydrogenated erucic acid and behenic acid are also suitable soap mixtures derived in particular from natural fatty acids, for example coconut, palm kernel or tallow fatty acids.
  • the anionic surfactants can be in the form of their sodium, potassium or ammonium salts and also as soluble salts of organic bases, such as mono-, di- or triethanolamine.
  • the sodium or potassium salts are preferred, in particular the sodium salts.
  • the surfactants can also be used in the form of their magnesium salts.
  • agents which contain 5 to 50% by weight, preferably 7.5 to 40% by weight and in particular 15 to 25% by weight, of one or more anionic surfactant (s).
  • the nonionic surfactants used are preferably alkoxylated, advantageously ethoxylated, in particular primary alcohols having preferably 8 to 18 carbon atoms and an average of 1 to 12 moles of ethylene oxide (EO) per mole of alcohol, in which the alcohol residue can be linear or preferably methyl-branched in the 2-position or may contain linear and methyl-branched radicals in the mixture, as are usually present in oxo alcohol radicals.
  • EO ethylene oxide
  • alcohol ethoxylates with linear residues from alcohols of native origin with 12 to 18 carbon atoms, for example from coconut, palm, tallow or oleyl alcohol, and an average of 2 to 8 EO per mole of alcohol are particularly preferred.
  • Preferred ethoxylated alcohols include, for example, Ci 2- i 4 alcohols containing 3 EO or 4 EO, C 9-11 - alcohol with 7 EO, C 13-15 alcohols containing 3 EO, 5 EO, 7 EO or 8 EO, Ci 2 -i 8 alcohols with 3 EO, 5 EO or 7 EO and mixtures thereof, and mixtures of Ci 2 -u alcohol with 3 EO and Ci 2 -i 8 alcohol with 5 EO.
  • the degrees of ethoxylation given represent statistical averages, which can be an integer or a fraction for a specific product.
  • Preferred alcohol ethoxylates have a narrow homolog distribution (narrow range ethoxylates, NRE).
  • fatty alcohols with more than 12 EO can also be used. Examples include tallow fatty alcohol with 14 EO, 25 EO, 30 EO or 40 EO.
  • Another class of preferably used nonionic surfactants, which are used either as the sole nonionic surfactant or in combination with other nonionic surfactants, are alkoxylated, preferably ethoxylated or ethoxylated and propoxylated, fatty acid alkyl esters, preferably with 1 to 4 carbon atoms in the alkyl chain, in particular fatty acid methyl ester.
  • alkyl polyglycosides Another class of nonionic surfactants that can be used advantageously are the alkyl polyglycosides (APG).
  • Alkypolyglycosides which can be used satisfy the general formula RO (G) 2 , in which R represents a linear or branched, in particular methyl-branched, saturated or unsaturated, aliphatic radical having 8 to 22, preferably 12 to 18, C atoms and G is the Is symbol which stands for a glycose unit with 5 or 6 carbon atoms, preferably for glucose.
  • the degree of glycosidation z is between 1.0 and 4.0, preferably between 1.0 and 2.0 and in particular between 1.1 and 1.4.
  • Linear alkyl polyglucosides ie alkyl polyglycosides, in which the polyglycosyl radical is a glucose radical and the alkyl radical is an n-alkyl radical are preferably used.
  • the surfactant-containing preparations according to the invention can preferably contain alkyl polyglycosides, with APG contents of more than 0.2% by weight, based on the entire preparation, of the preparations intended for washing, rinsing or cleaning purposes being preferred.
  • Particularly preferred surfactant-containing preparations contain APG in amounts of 0.2 to 10% by weight, preferably in amounts of 0.2 to 5% by weight and in particular in amounts of 0.5 to 3% by weight.
  • Nonionic surfactants of the amine oxide type for example N-coconut alkyl-N, N-dimethylamine oxide and N-tallow alkyl-N, N-dihydroxyethylamine oxide, and the fatty acid alkanolamides can also be suitable.
  • the amount of these nonionic surfactants is preferably not more than that of the ethoxylated fatty alcohols, in particular not more than half of them.
  • Other suitable surfactants are polyhydroxy fatty acid amides of the formula (I),
  • R 4 CO is an aliphatic acyl radical having 6 to 22 carbon atoms
  • R 5 is hydrogen
  • [Z 1 ] is a linear or branched polyhydroxyalkyl radical having 3 to 10 carbon atoms and 3 to 10 Hydroxyl groups.
  • the polyhydroxy fatty acid amides are known substances which can usually be obtained by reductive amination of a reducing sugar with ammonia, an alkylamine or an alkanolamine and subsequent acylation with a fatty acid, a fatty acid alkyl ester or a fatty acid chloride.
  • the group of polyhydroxy fatty acid amides also includes compounds of the formula (II)
  • R ⁇ represents a linear or branched alkyl or alkenyl radical having 7 to 12 carbon atoms
  • R 7 represents a linear, branched or cyclic alkyl radical or an aryl radical having 2 to 8 carbon atoms
  • R 8 represents a linear, branched or cyclic alkyl radical or Aryl radical or an oxy-alkyl radical having 1 to 8 carbon atoms, C 1-4 alkyl or phenyl radicals being preferred
  • [Z 2 ] representing a linear polyhydroxyalkyl radical whose alkyl chain is substituted by at least two hydroxyl groups, or alkoxylated, preferably ethoxylated or propylated derivatives of this residue.
  • [Z 2 ] is preferably obtained by reductive amination of a reduced sugar, for example glucose, fructose, maltose, lactose, galactose, mannose or xylose.
  • a reduced sugar for example glucose, fructose, maltose, lactose, galactose, mannose or xylose.
  • the N-alkoxy- or N-aryloxy-substituted compounds can then, for example, as described in WO-A-95/07331, by Reaction with fatty acid methyl esters in the presence of an alkoxide as a catalyst can be converted into the desired polyhydroxy fatty acid amides.
  • cationic surfactants in addition to anionic and nonionic surfactants.
  • Cationic surfactants may be mentioned in particular as textile softening substances.
  • Examples of cationic surfactants are in particular quaternary ammonium compounds, cationic polymers and emulsifiers.
  • Suitable examples are quaternary ammonium compounds of the formulas (III) and (IV)
  • R a and R b are an acyclic alkyl radical having 12 to 24 carbon atoms
  • R c is a saturated C r C 4 alkyl or hydroxyalkyl radical
  • R d is either equal to R a , R b or R c or for is an aromatic residue.
  • X ⁇ stands for either a halide, methosulfate, methophosphate or phosphate ion as well as mixtures of these.
  • Examples of cationic compounds of the formula (III) are didecyldimethylammonium chloride, ditallow dimethylammonium chloride or dihexadecylammonium chloride.
  • Ester quats are so-called ester quats. Esterquats are characterized by excellent biodegradability.
  • R e represents an aliphatic acyl radical having 12 to 22 carbon atoms with 0, 1, 2 or 3 double bonds
  • R f stands for H, OH or O (CO) R h
  • R g independently of R f stands for H, OH or 0 (CO) R '
  • R h and R' independently of one another each represent an aliphatic acyl radical with 12 to 22 carbon atoms with 0, 1, 2 or 3 double bonds
  • m, n and p can each independently have the value 1, 2 or 3.
  • X " can either be a halide, methosulfate, Methophosphate or phosphate ion and mixtures of these.
  • Compounds are preferred which contain the group O (CO) R h for R f and alkyl radicals having 16 to 18 carbon atoms for R c and R h .
  • Compounds in which R 9 is also OH are particularly preferred.
  • Examples of compounds of the formula (IV) are methyl N- (2-hydroxyethyl) -N, N-di (tallow acyl oxyethyl) ammonium methosulfate, bis (palmitoyl) ethyl hydroxyethyl methyl ammonium methosulfate or methyl -N, N-bis (acyloxyethyl) -N- (2-hydroxyethyl) ammonium methosulfate.
  • quaternized compounds of the formula (IV) which have unsaturated alkyl chains
  • Commercial examples are dialkoyloxyalkylammoniummethosulfate sold by Stepan under the name Stepantex® ® methyl hydroxyalkyl or known by Dehyquart® ® products from Cognis or known by Rewoquat ® products from Goldschmidt-Witco.
  • Further preferred compounds are the diesterquats of the formula (V), which are available under the names Rewoquat ® W 222 LM or CR 3099 and, in addition to the softness, also ensure stability and color protection.
  • R k and R 1 each independently represent an aliphatic acyl radical having 12 to 22 carbon atoms with O, 1, 2 or 3 double bonds.
  • R m is H or a saturated alkyl radical having 1 to 4 carbon atoms
  • R n and R 0 are each independently an aliphatic, saturated or unsaturated alkyl radical having 12 to 18 carbon atoms
  • R n can alternatively also be O (CO) R P
  • R p is an aliphatic, saturated or unsaturated alkyl radical having 12 to 18 carbon atoms
  • Z is an NH group or oxygen
  • q can have integer values between 1 and 4.
  • R q , R r and R s independently of one another represent a Ci- 4 -alkyl, alkenyl or hydroxyalkyl group
  • R 1 and R u each independently represent a Cs_ 28 alkyl group
  • r is a number between 0 and 5.
  • short-chain, water-soluble, quaternary ammonium compounds such as trihydroxyethylmethylammonium methosulfate or the alkyltrimethylammonium chloride, dialkyldimethylammonium chloride and trialkylmethylammonium chloride, e.g. B. cetyltrimethylammonium chloride, stearyltrimethylammonium chloride, distearyldimethylammonium chloride, lauryldimethylammonium chloride, lauryldimethylbenzylammonium chloride and tricetylmethylammonium chloride.
  • Protonated alkylamine compounds which have a plasticizing effect and the non-quaternized, protonated precursors of the cationic emulsifiers are also suitable.
  • the quaternized protein hydrolyzates are further cationic compounds which can be used according to the invention.
  • Suitable cationic polymers include the polyquaternium polymers as described in the CTFA Cosmetic Ingredient Dictionary (The Cosmetic, Toiletry and Fragrance, Inc., 1997), in particular the polyquaternium-6, polyquaternium-7, polyquaternium- also known as merquats.
  • 10-polymers (Ucare Polymer IR 400; Amerchol), polyquaternium-4 copolymers, such as graft copolymers with a cellulose skeleton and quaternary ammonium groups which are bonded via allyldimethylammonium chloride, cationic cellulose derivatives, such as cationic guar, such as guar-hydroxypropyltriammonium chloride, and similar quaternized guatemate Derivatives (e.g. Cosmedia Guar, manufacturer: Cognis GmbH), cationic quaternary sugar derivatives (cationic alkyl polyglucosides), e.g. B.
  • polyquaternium-4 copolymers such as graft copolymers with a cellulose skeleton and quaternary ammonium groups which are bonded via allyldimethylammonium chloride
  • cationic cellulose derivatives such as cationic guar, such as guar-hydroxypropyltriammonium chloride, and
  • Glucquat ® 100 according to CTFA nomenclature a "Lauryl Methyl Gluceth-10 Hydroxypropyl Dimonium Chloride", copolymers of PVP and dimethylaminomethacrylate, copolymers of vinylimidazole and vinylpyrrolidone, aminosilicone polymers and copolymers,
  • polyquatem for example, Luviquat Care by BASF.
  • cationic biopolymers based on chitin and derivatives thereof for example, under the trade designation chitosan ® (manufacturer: Cognis) polymer obtainable.
  • cationic silicone oils such as, for example, the commercially available products Q2-7224 (manufacturer: Dow Corning; a stabilized trimethylsilylamodimethicone), Dow Corning 929 emulsion (containing a hydroxylamino-modified silicone, which is also referred to as amodimethicone), SM -2059 (manufacturer: General Electric), SLM-55067 (manufacturer: Wacker) Abil ® -Quat 3270 and 3272 (manufacturer: Goldschmidt-Rewo; diquartare Polydimethylsiloxane, Quatemium-80), and Siliconquat Rewoquat ® SQ 1 (Tegopren ® 6922, manufacturer: Goldschmidt-Rewo).
  • Q2-7224 commercially available products
  • Dow Corning a stabilized trimethylsilylamodimethicone
  • Dow Corning 929 emulsion containing a hydroxylamino-modified silicone, which
  • the alkylamidoamines can be in their non-quaternized or, as shown, their quaternized form.
  • R v can be an aliphatic acyl radical with 12 to 22 carbon atoms with 0, 1, 2 or 3 double bonds, s can assume values between 0 and 5.
  • R w and R x each independently represent H, Ci_ 4 -A! Kyl or hydroxyalkyl.
  • Preferred compounds are fatty acid amidoamines such as the stearylamidopropyldimethylamine available under the name Tego Amid ® S 18 or the 3-tallowamidopropyl trimethylammonium methosulfate available under the name Stepantex ® X 9124, which not only have a good conditioning effect but also an ink transfer inhibiting effect and especially their good effect distinguish biodegradability.
  • cationic surfactants are used, they are preferably present in the preparations in amounts of from 0.01 to 10% by weight, in particular from 0.1 to 3.0% by weight.
  • the total surfactant content in the agents according to the invention can be between 5 and 50% by weight, preferably between 10 and 35% by weight.
  • builders are the most important ingredients in detergents and cleaning agents.
  • Builders usually used in detergents and cleaning agents can be used in the surfactant-containing preparations according to the invention be included, in particular thus zeolites, silicates, carbonates, organic cobuilders and - where there are no ecological prejudices against their use - also the phosphates.
  • Suitable crystalline, layered sodium silicates have the general formula NaMSi x O 2x + I 'H 2 O, where M is sodium or hydrogen, x is a number from 1, 9 to 4 and y is a number from 0 to 20 and preferred values for x 2, 3 or 4.
  • M sodium or hydrogen
  • x is a number from 1, 9 to 4
  • y is a number from 0 to 20 and preferred values for x 2, 3 or 4.
  • Such crystalline layered silicates are described, for example, in European patent application EP-AO 164 514.
  • Preferred crystalline layered silicates of the formula given are those in which M represents sodium and x assumes the values 2 or 3.
  • both ⁇ - and ⁇ -sodium disilicate Na 2 Si 2 Os "yH 2 O are preferred, wherein ⁇ -sodium disilicate can be obtained, for example, by the method described in international patent application WO-A-91/08171.
  • the delay in dissolution compared to conventional amorphous sodium silicates can be caused in various ways, for example by surface treatment, compounding, compacting / compression or by overdrying.
  • So-called X-ray amorphous silicates, which also have a delay in dissolution compared to conventional water glasses, are described, for example, in German patent application DE-A-44 00 024.
  • the products have microcrystalline areas of size 10 to a few hundred nm, values up to max. 50 nm and in particular up to max. 20 nm are preferred.
  • Compacted / compacted amorphous silicates, compounded amorphous silicates and over-dried X-ray amorphous silicates are particularly
  • An optionally used finely crystalline, synthetic and bound water-containing zeolite is preferably zeolite A and / or P.
  • Zeolite of the P type is zeolite MAP (eg commercial product: Doucil A24 from the company Crosfield) is particularly preferred.
  • zeolite X and mixtures of A, X and / or P are also suitable.
  • Commercially available and can preferably be used in the context of the present invention for example a co-crystallizate of zeolite X and zeolite A (about 80% by weight of zeolite X) ), which is sold by CONDEA Augusta SpA under the brand name VEGOBOND AX ® and by the formula
  • Suitable zeolites have an average particle size of less than 10 ⁇ m (volume distribution; measurement method: Coulter Counter) and preferably contain 18 to 22% by weight, in particular 20 to 22% by weight, of bound water.
  • phosphates as builders in detergents, provided that such use should not be avoided for ecological reasons.
  • the sodium salts of orthophosphates, pyrophosphates and in particular tripolyphosphates are particularly suitable.
  • Usable organic builders are, for example, the polycarboxylic acids which can be used in the form of their sodium salts, polycarboxylic acids being understood to mean those carboxylic acids which carry more than one acid function.
  • these are citric acid, adipic acid, succinic acid, glutaric acid, malic acid, tartaric acid, maleic acid, fumaric acid, sugar acids, aminocarboxylic acids, nitrilotriacetic acid (NTA), as long as their use is not objectionable for ecological reasons, and mixtures of these.
  • Preferred salts are the salts of polycarboxylic acids such as citric acid, adipic acid, succinic acid, glutaric acid, tartaric acid, sugar acids and mixtures of these.
  • the acids themselves can also be used.
  • the acids typically also have the property of an acidifying component and thus also serve to establish a lower and milder pH of surfactant-containing preparations according to Invention.
  • citric acid, succinic acid, glutaric acid, adipic acid, gluconic acid and any mixtures of these should be mentioned in particular.
  • Polymeric polycarboxylates are also suitable as builders. These are, for example, the alkali metal salts of polyacrylic acid or polymethacrylic acid, for example those with a relative molecular weight of 500 to 70,000 g / mol.
  • the molar masses given for polymeric polycarboxylates are weight-average molar masses M w of the particular acid form, which were determined in principle by means of gel permeation chromatography (GPC), a UV detector being used.
  • GPC gel permeation chromatography
  • the measurement was carried out against an external polyacrylic acid standard, which provides realistic molecular weight values due to its structural relationship to the polymers investigated. This information differs significantly from the molecular weight information for which polystyrene sulfonic acids are used as standard.
  • the molar masses measured against polystyrene acids are generally significantly higher than the molar masses specified in the context of the present invention.
  • Suitable polymers are, in particular, polyacrylates, which preferably have a molecular weight of 2,000 to 20,000 g / mol. Because of their superior solubility, the short-chain polyacrylates with molecular weights of 2,000 to 10,000 g / mol, particularly preferably 3,000 to 5,000 g / mol, can in turn be preferred from this group.
  • copolymeric polycarboxylates in particular those of acrylic acid with methacrylic acid or of acrylic acid or methacrylic acid with maleic acid.
  • Copolymers of acrylic acid with maleic acid which contain 50 to 90% by weight of acrylic acid and 50 to 10% by weight of maleic acid have proven to be particularly suitable.
  • Their relative molar mass, based on free acids, is generally 2,000 to 70,000 g / mol, preferably 20,000 to 50,000 g / mol and in particular 30,000 to 40,000 g / mol.
  • the (co) polymeric polycarboxylates can be used either as a powder or as an aqueous solution.
  • the content of (co) polymeric polycarboxylates in the washing and cleaning agents according to the invention is preferably 0.5 to 20% by weight, in particular 3 to 10% by weight.
  • the polymers can also contain allylsulfonic acids, allyloxybenzenesulfonic acid and methallylsulfonic acid as a monomer.
  • Biodegradable polymers of more than two different monomer units are also particularly preferred, for example those which contain, as monomers, salts of acrylic acid and maleic acid and also vinyl alcohol or vinyl alcohol derivatives or salts of acrylic acid and 2-alkylallylsulfonic acid and sugar derivatives.
  • copolymers are those which preferably contain acrolein and acrylic acid / acrylic acid salts or acrolein and vinyl acetate as monomers.
  • polymeric aminodicarboxylic acids their salts or their precursor substances.
  • Particularly preferred are polyaspartic acids or their salts and derivatives, some of which, in addition to co-builder properties, also have a bleach-stabilizing effect.
  • Suitable builder substances are polyacetals, which can be obtained by reacting dialdehydes with polyolcarboxylic acids which have 5 to 7 carbon atoms and at least 3 hydroxyl groups.
  • Preferred polyacetals are obtained from dialdehydes such as glyoxal, glutaraldehyde, terephthalaldehyde and mixtures thereof and from polyol carboxylic acids such as gluconic acid and / or glucoheptonic acid.
  • Other suitable organic builder substances are dextrins, for example oligomers or polymers of carbohydrates, which can be obtained by partial hydrolysis of starches. The hydrolysis can be carried out by customary, for example acid or enzyme-catalyzed, processes.
  • DE dextrose equivalent
  • Both maltodextrins with a DE between 3 and 20 and dry glucose syrups with a DE between 20 and 37 as well as so-called yellow dextrins and white dextrins with higher molar masses in the range from 2,000 to 30,000 g / mol can be used.
  • a preferred dextrin is described in British patent application 94 19 091.
  • oxidized derivatives of such dextrins are their reaction products with oxidizing agents which are capable of oxidizing at least one alcohol function of the saccharide ring to the carboxylic acid function.
  • oxidizing agents capable of oxidizing at least one alcohol function of the saccharide ring to the carboxylic acid function.
  • An oxidized oligosaccharide is also suitable, although a product oxidized at C 6 of the saccharide ring can be particularly advantageous.
  • Ethylene diamine N, N'-disuccinate (EDDS) is preferably used in the form of the sodium or magnesium salts.
  • Glycerol disuccinates and glycerol trisuccinates are also preferred in this context. Suitable amounts used in zeolite and / or silicate formulations are 3 to 15% by weight.
  • organic co-builders are, for example, acetylated hydroxycarboxylic acids or their salts, which may also be used in Lactone form can be present and which contain at least 4 carbon atoms and at least one hydroxy group and a maximum of two acid groups.
  • phosphonates are in particular hydroxyalkane or aminoalkanephosphonates.
  • Preferred aminoalkane phosphonates are examples
  • Ethylenediaminetetramethylenephosphonate (EDTMP)
  • Diethylene triamine pentamethylene phosphonate (DTPMP) as well as their higher homologues in question. They are preferably in the form of the neutral reacting sodium salts, e.g. used as the hexasodium salt of EDTMP or as the hepta and octasodium salt of DTPMP.
  • HEDP is preferably used as the builder from the class of the phosphonates.
  • the aminoalkanephosphonates also have a pronounced ability to bind heavy metals. Accordingly, in particular if the surfactant-containing preparations according to the invention also contain bleach, it may be preferred to use aminoalkanephosphonates, in particular DTPMP, or to use mixtures of the phosphonates mentioned.
  • bleaching agents which can be used are, for example, sodium percarbonate, peroxypyrophosphates, citrate perhydrates and H 2 O 2 -producing peracidic salts or peracids, such as perbenzoates, peroxophthalates, diperazelaic acid, phthaloiminoperic acid or diperdodecanedioic acid. If cleaning or bleaching preparations for machine dishwashing are produced, bleaching agents from the group of organic ones can also be used Bleach can be used.
  • Typical organic bleaching agents are the diacyl peroxides, such as dibenzoyl peroxide.
  • Other typical organic bleaching agents are peroxy acids, examples of which include alkyl peroxy acids and aryl peroxy acids.
  • Preferred representatives are (a) peroxybenzoic acid and its ring-substituted derivatives, such as alkylperoxybenzoic acids, but also peroxy- ⁇ -naphthoic acid and magnesium monoperphthalate; (b) the aliphatic or substituted aliphatic peroxy acids, such as peroxylauric acid, peroxystearic acid, ⁇ -phthalimidoperoxycaproic acid [phthaloiminoperoxyhexanoic acid (PAP)], o-carboxybenzamido-per-oxycaproic acid, N-nonenylamido operadipic acid and N-succinate; and (c) aliphatic and araliphatic peroxide icarboxylic acids, such as 1,
  • bleach activators can be incorporated into the surfactant-containing preparations.
  • Bleach activators which can be used are compounds which, under perhydrolysis conditions, give aliphatic peroxocarboxylic acids having preferably 1 to 10 C atoms, in particular 2 to 4 C atoms, and / or optionally substituted perbenzoic acid. Substances are suitable which carry O- and / or N-acyl groups of the number of carbon atoms mentioned and / or optionally substituted benzoyl groups.
  • TAED tetraacetylethylenediamine
  • bleach catalysts can also be incorporated into the surfactant-containing preparations.
  • These substances are bleach-enhancing transition metal salts or transition metal complexes such as, for example, Mn, Fe, Co, Ru or Mo salt complexes or carbonyl complexes.
  • Mn, Fe, Co, Ru, Mo, Ti, V and Cu complexes with N-containing tripod ligands as well as Co, Fe, Cu and Ru amine complexes can also be used as bleaching catalysts ,
  • Suitable enzymes are those from the class of proteases, lipases, amylases, cellulases or mixtures thereof. Enzymatic active ingredients obtained from bacterial strains or fungi such as Bacillus subtilis, Bacillus licheniformis and Streptomyces griseus are particularly suitable. Proteases of the subtilisin type and in particular proteases which are obtained from Bacillus lentus are preferably used.
  • Enzyme mixtures for example of protease and amylase or protease and lipase or protease and cellulase or of cellulase and lipase or of protease, amylase and lipase or protease, lipase and cellulase, but in particular mixtures containing cellulase, are of particular interest.
  • Peroxidases or oxidases have also proven to be suitable in some cases.
  • the enzymes can be adsorbed on carriers and / or embedded in coating substances in order to protect them against premature decomposition.
  • the proportion of the enzymes, enzyme mixtures or enzyme granules in the surfactant-containing preparations according to the invention can be, for example, about 0.1 to 5% by weight, preferably 0.1 to about 2% by weight.
  • optical brighteners are optical brighteners.
  • the optical brighteners customary in detergents can be used here.
  • Examples of optical brighteners are derivatives of diaminostilbenedisulfonic acid or its alkali metal salts.
  • Brighteners of the type of Substituted Diphenylstyryle contained in the partial portions (detergent preparations) of the surfactant-containing preparations according to the invention for. B. the alkali salts of 4,4'-bis (2-sulfostyryl-) diphenyl, 4,4'-bis (4-chloro-3-sulfostyryl-) diphenyl or 4- (4-chlorostyryl-) 4 '- (2nd -sulfostyryl-) biphenyl. Mixtures of the aforementioned brighteners can also be used.
  • UV protection substances can absorb onto the treated textiles and improve the lightfastness of the fibers and / or the lightfastness of the other recipe components.
  • UV absorbers are understood to mean organic substances (light protection filters) which are able to absorb ultraviolet rays and release the absorbed energy in the form of longer-wave radiation, for example heat.
  • Compounds which have these desired properties are, for example, the compounds and derivatives of benzophenone which are active by radiationless deactivation and have substituents in the 2- and / or 4-position.
  • substituted benzotriazoles such as the water-soluble benzenesulfonic acid-3- (2H-benzotriazol-2-yl) -4-hydroxy-5- (methylpropyl) monosodium salt (Ciba ® Fast H), in 3- phenyl-substituted acrylates (cinnamic acid derivatives) , optionally with cyano groups in the 2-position, salicylates, organic Ni complexes and natural substances such as umbelliferone and the body's own urocanoic acid.
  • 3-Benzylidene camphor or 3-benzylidene norcampher and its derivatives, for example 3- (4-methylbenzylidene) camphor are to be mentioned as UV-B absorbers, as described in EP 0693471 B1; 4-aminobenzoic acid derivatives, preferably 4-
  • esters of cinnamic acid preferably 2-ethylhexyl 4-methoxycinnamate, propyl 4-methoxycinnamate, isoamyl 4-methoxycinnamate, 2-ethylhexyl 2-cyano-3,3-phenylcinnamate (octocrylene);
  • Esters of salicylic acid preferably salicylic acid 2-ethylhexyl ester, salicylic acid 4-isopropylbenzyl ester, salicylic acid homomenthy- lester;
  • Derivatives of benzophenone preferably 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone;
  • Sulfonic acid derivatives of 3-benzylidene camphor e.g. 4- (2-oxo-3-bomylidene-methyl) benzenesulfonic acid and 2-methyl-5- (2-oxo-3-bomylidene) sulfonic acid and their salts.
  • UV-A filters -4'-methoxydibenzoylmethane (Parsol 1789), 1-phenyl-3- (4'-isopropylphenyl) propane-1, 3-dione and enamine compounds as described in DE 19712033 A1 (BASF).
  • the UV-A and UV-B filters can of course also be used in mixtures.
  • insoluble light-protection pigments namely finely dispersed, preferably nanoized metal oxides or salts
  • suitable metal oxides are, in particular, zinc oxide and titanium dioxide and, in addition, oxides of iron, zirconium, silicon, manganese, aluminum and cerium and mixtures thereof.
  • Silicates (talc), barium sulfate or zinc stearate can be used as salts.
  • the oxides and salts are already used in the form of the pigments for skin-care and skin-protecting emulsions and decorative cosmetics.
  • the particles should have an average diameter of less than 100 nm, preferably between 5 and 50 nm and in particular between 15 and 30 nm.
  • the pigments can also be surface-treated, ie hydrophilized or hydrophobicized.
  • Typical examples are coated titanium dioxides, such as titanium dioxide T 805 (Degussa) or Eusolex® T2000 (Merck). Silicones, and in particular trialkoxyoctylsilanes or simethicones, are particularly suitable as hydrophobic coating agents. Micronized zinc oxide is preferably used. Further suitable UV light protection filters can be found in the overview by P.Finkel in S ⁇ FW-Journal 122, 543 (1996).
  • the UV absorbers are usually used in amounts of from 0.01% by weight to 5% by weight, preferably from 0.03% by weight to 1% by weight.
  • dyes are preferred according to the invention.
  • Dyes are preferred here, as are usually used to improve the optical product appearance in the washing, rinsing, cleaning and textile treatment agents according to the invention.
  • the choice of such dyes does not pose any difficulties for the person skilled in the art, in particular since such customary dyes have a long shelf life and are insensitive to the other ingredients of the detergent preparations and to light, and have no pronounced substantivity towards textile fibers in order not to dye them.
  • the dyes are present in the washing and / or cleaning agents according to the invention in amounts of less than 0.01% by weight.
  • polymers Another class of additives that can be added to the washing and / or cleaning agents according to the invention are polymers.
  • polymers which show cobuilder properties during washing or cleaning or rinsing, for example polyacrylic acids, also modified polyacrylic acids or corresponding copolymers.
  • Another group of polymers are polyvinyl pyrrolidone and other graying inhibitors, such as copolymers of polyvinyl pyrrolidone, cellulose ether and the like. So-called soil repellents, as are described in detail below, are also preferred as polymers.
  • the detergents and cleaning agents can also contain so-called soil repellents, that is to say polymers which attach to fibers, have a positive influence on the oil and fat washability from textiles and thus counteract any soiling in a targeted manner.
  • soil repellents that is to say polymers which attach to fibers
  • the preferred oil and fat-dissolving components include, for example, nonionic cellulose ethers such as methyl cellulose and methyl hydroxypropyl cellulose with a proportion of methoxy groups of 15 to 30% by weight and of hydroxypropoxy groups of 1 to 15% by weight in each case based on the nonionic cellulose ether, and the polymers of phthalic acid and / or terephthalic acid or their derivatives known from the prior art, in particular polymers of ethylene terephthalates and / or polyethylene glycol terephthalates or anionically and / or nonionically modified derivatives thereof. Of these, the sulfonated derivatives of phthalic acid and terephthalic acid polymers are particularly preferred.
  • the preparations can also contain solvents.
  • suitable solvents are monohydric or polyhydric alcohols with 1 to 4 carbon atoms.
  • Preferred alcohols are ethanol, 1, 2-propanediol, glycerin and any mixtures thereof.
  • the solvents can be contained in liquid preparations in an amount of 2 to 12% by weight, based on the finished preparation.
  • the additives mentioned are added to the washing and / or cleaning agents in amounts of at most 30% by weight, preferably 2 to 20% by weight.
  • This list of detergent and cleaning agent ingredients that can occur in the washing, rinsing or cleaning agents according to the invention is by no means exhaustive, but merely reflects the essential typical ingredients of such agents.
  • organic agents can also be used in the agents Solvent may be included. It is preferably monohydric or polyhydric alcohols having 1 to 4 carbon atoms. Preferred alcohols in such agents are ethanol, 1, 2-propanediol, glycerol and mixtures of these alcohols. In preferred embodiments, such agents contain 2 to 12% by weight of such alcohols.
  • liquid or solid detergents are particularly preferred. Also particularly preferred are detergents and cleaning agents that are suitable for delicates or gentle treatment of sensitive textiles.
  • textile care products are also, in particular,
  • Textile aftertreatment agents preferably textile conditioning agents, fabric softeners or dryer sheets, which contain patchouli oil, patchouli alcohol and / or its derivatives.
  • Fabric softener compositions for rinse bath finishing are widely described in the prior art. Typically, these compositions contain as the active substance a cationic quaternary ammonium compound which is dispersed in water. Depending on the content of active substance in the finished plasticizer composition, one speaks of dilute, ready-to-use products (active substance contents below 7% by weight) or so-called concentrates (active substance content above 7% by weight). Because of the lower volume and the associated lower packaging and transport costs, the textile softener concentrates have advantages from an ecological point of view and have become more and more established on the market.
  • fabric softeners according to the invention preferably contain cationic surfactants, which have already been described in detail above. These agents according to the invention particularly preferably contain so-called ester quats.
  • esterquats are used according to the invention with particular preference which can be prepared in a manner known per se by reacting trialkanolamines with a mixture of fatty acids and dicarboxylic acids, optionally subsequent alkoxylation of the reaction product and quaternization is described in DE 195 39 846.
  • esterquats produced in this way are outstandingly suitable for producing portions according to the invention which can be used as fabric softeners. Since, depending on the choice of the trialkanolamine, the fatty acids and the dicarboxylic acids and the quaternizing agent, a large number of suitable products can be prepared and used in the agents according to the invention, a description of the esterquats to be used according to the invention via their route of production is more precise than the specification of a general formula.
  • fabric softeners are preferred in which a reaction product of trialkanolamines with a mixture of fatty acids and dicarboxylic acids in a molar ratio of 1:10 to 10: 1, preferably 1: 5 to 5: 1, which optionally alkoxylates and then in itself was quaternized in a known manner, is present in amounts of 2 to 60, preferably 3 to 35 and in particular 5 to 30% by weight.
  • triethanolamine is particularly preferred, so that further preferred fabric softeners of the present invention are a reaction product of triethanolamine with a mixture of fatty acids and dicarboxylic acids in a molar ratio of 1:10 to 10: 1, preferably 1: 5 to 5: 1, which if appropriate alkoxylated and then in a conventional manner was quaternized, in amounts of 2 to 60, preferably 3 to 35 and in particular 5 to 30 wt .-%.
  • All acids obtained from vegetable or animal oils and fats can be used as fatty acids in the reaction mixture to produce the esterquats.
  • a fatty acid that is not solid at room temperature, i.e. pasty to liquid, fatty acid can be used.
  • the fatty acids can be saturated or mono- to polyunsaturated regardless of their physical state.
  • pure fatty acids can be used, but also the technical fatty acid mixtures obtained from the cleavage of fats and oils, these mixtures again being clearly preferred from an economic point of view.
  • individual species or mixtures of the following acids can be used in the reaction mixtures for producing the esterquats for the clear aqueous fabric softener according to the invention: caprylic acid, pelargonic acid, capric acid, lauric acid, myristic acid, palmitic acid, stearic acid, octadecano-12-ol acid, arachic acid, behenic acid , Lignoceric acid, cerotinic acid, melissic acid, 10-undecenoic acid, petroselinic acid, petroselaidic acid, oleic acid, elaidic acid, ricinoleic acid, linolaidic acid, ⁇ - and ß-elaestainic acid, gadoleic acid, erucic acid, brassidic acid.
  • the fatty acids with an odd number of carbon atoms can also be used, for example undecanoic acid, tridecanoic acid, pentadecanoic acid, heptadecanoic acid, nonadecanoic acid, heneicosanoic acid, tricosanoic acid, pentacosanoic acid, heptacosanoic acid.
  • fatty acids of the formula XIII in the reaction mixture for the preparation of the esterquats is preferred, so that preferred fabric softeners are a reaction product of trialkanolamines with a mixture of fatty acids of the formula IX, R 1 -CO-OH (IX)
  • R1-C0- represents an aliphatic, linear or branched acyl radical having 6 to 22 carbon atoms and 0 and / or 1, 2 or 3 double bonds and dicarboxylic acids in a molar ratio of 1:10 to 10: 1, preferably 1: 5 to 5 : 1, which was optionally alkoxylated and then quaternized in a manner known per se, contained in the compositions in amounts of 2 to 60, preferably 3 to 35 and in particular 5 to 30% by weight.
  • Suitable dicarboxylic acids which are suitable for producing the esterquats to be used in the agents according to the invention are, in particular, saturated or mono- or polyunsaturated ⁇ . ⁇ dicarboxylic acids.
  • Dicarboxylic acids which follow the general formula XIII are preferably used in the reaction mixture, so that agents according to the invention are preferred which are a reaction product of trialkanolamines with a mixture of fatty acids and dicarboxylic acids of the formula X,
  • X represents an optionally hydroxyl-substituted alkylene group with 1 to 10 carbon atoms, in a molar ratio of 1:10 to 10: 1, preferably 1: 5 to 5: 1, which was optionally alkoxylated and then quaternized in a manner known per se, in quantities from 2 to 60, preferably 3 to 35 and in particular 5 to 30% by weight in the compositions.
  • agents which contain a reaction product of triethanolamine with a mixture of fatty acids and adipic acid in a molar ratio of 1: 5 to 5: 1, preferably 1: 3 to 3: 1, which was subsequently quaternized in a manner known per se, contained in the compositions in amounts of 2 to 60, preferably 3 to 35 and in particular 5 to 30% by weight
  • the agents according to the invention can also be provided with additional benefits.
  • color transfer inhibiting compositions agents with an "anti-gray formula", agents with ironing relief, agents with special fragrance release, agents with improved dirt release or prevention of re-soiling, antibacterial agents, UV protection agents, color-refreshing agents, etc. can be formulated.
  • the agents according to the invention can contain synthetic anti-crease agents. These include, for example, synthetic products based on fatty acids, fatty acid esters. Fatty acid amides, alkylol esters, alkylolamides or fatty alcohols, which are mostly reacted with ethylene oxide, or products based on lecithin or modified phosphoric acid esters.
  • Antistatic agents increase the surface conductivity and thus enable the flow of charges that have formed to improve.
  • External antistatic agents are generally substances with at least one hydrophilic molecular ligand and give a more or less hygroscopic film on the surfaces. These mostly surface-active antistatic agents can be broken down into nitrogen-containing (amines, amides, quaternary ammonium compounds), phosphorus-containing (phosphoric acid esters) and Subdivide sulfur-containing (alkyl sulfonates, alkyl sulfates) antistatic agents. Lauryl (or stearyl) dimethylbenzylammonium chlorides are suitable as antistatic agents for textiles or as an additive to detergents, with an additional softening effect.
  • silicone derivatives can be used in the agents according to the invention. These additionally improve the rinsing behavior of the agents according to the invention due to their foam-inhibiting properties.
  • Preferred silicone derivatives are, for example, polydialkyl or alkylarylsiloxanes in which the alkyl groups have one to five carbon atoms and are completely or partially fluorinated.
  • Preferred silicones are polydimethylsiloxanes, which can optionally be derivatized and are then amino-functional or quaternized or have Si-OH, Si-H and / or Si-Cl bonds.
  • the viscosities of the preferred silicones at 25 ° C. are in the range between 100 and 100,000 centistokes, it being possible for the silicones to be used in amounts between 0.2 and 5% by weight, based on the total agent.
  • the agents according to the invention can also contain UV absorbers, which absorb onto the treated textiles and improve the light resistance of the fibers.
  • Compounds which have these desired properties are, for example, the compounds and derivatives of benzophenone which are active by radiationless deactivation and have substituents in the 2- and / or 4-position.
  • Substituted benzotriazoles, phenyl-substituted acrylates (cinnamic acid derivatives), optionally with cyano groups in the 2-position, salicylates, organic Ni complexes and natural substances such as umbelliferone and the body's own urocanoic acid are also suitable.
  • Further objects of the present invention are packaging, in particular packaging for food, filter media, building materials, auxiliary building materials, textiles, furs, paper, skins or leather, which contain patchouli oil, patchouli alcohol and / or its derivatives and / or which have been equipped with an agent according to the invention.
  • the paper or the packaging, surfaces, textiles, furs, skins or leather is finished in a manner known to those skilled in the art, for example by immersing or spraying the paper or textiles, furs, skins or leather in a suitably concentrated solution of an agent according to the invention.
  • works of art on paper, parchment, wood and / or canvas can also be protected from, or freed from, microorganisms, in particular mold.
  • the filter media, building materials or auxiliary building materials are equipped, for example, by mechanical incorporation or application of a suitably concentrated solution of an agent according to the invention in or on the filter media, building materials or auxiliary building materials.
  • Patchouli oil and solutions of patchouli alcohol can advantageously be applied or incorporated particularly well onto or into such building and construction aids. Subsequent finishing of the building materials or auxiliary materials or recharging after prolonged use of building materials or auxiliary materials already equipped, for example in the case of sealing compounds, by application of the agents according to the invention is therefore possible without any problems.
  • the building materials and / or auxiliary materials equipped according to the invention are preferably selected from adhesives, sealants, fillers and paints, plastics, paints, paints, plaster, mortar, screed, concrete, insulating materials and primers.
  • Particularly preferred building materials or construction aids are joint sealants (for example silicone-containing joint sealants), wallpaper paste, plaster, carpet fixers, silicone adhesives, tile adhesives, emulsion paints and paints for exterior and / or interior use.
  • Sealants and especially joint sealants typically contain organic polymers and, in many cases, mineral or organic fillers and other additives.
  • Suitable polymers are, for example, thermoplastic elastomers, as described in DE-A-3602526 by the applicant, preferably polyurethanes and acrylates.
  • Suitable polymers are also mentioned in the published patent applications DE-A-3726547, DE-A-4029504 and DE-A-4009095 by the applicant and in DE-A-19704553 and DE-A-4233077, which are hereby incorporated by reference in their entirety ,
  • Sealants and especially joint sealants typically contain organic polymers and, in many cases, mineral or organic fillers and other additives.
  • Suitable polymers are, for example, thermoplastic elastomers, as described in DE-A-3602526 by the applicant, preferably polyurethanes and acrylates. Suitable polymers are also mentioned in the published patent applications DE-A-3726547, DE-A-4029504 and DE-A-4009095 by the applicant and in DE-A-19704553 and DE-A-4233077, which are hereby incorporated by reference in their entirety ,
  • the sealing compounds (sealants or
  • Sealant mixtures preferably contain 0.0001-1.5% by weight of patchoui oil, patchouli alcohol and / or its derivatives. Ranges between 0.001 and 1.0% by weight, in particular up to 0.5% by weight, are particularly preferred.
  • sealants according to the invention can be finished both in the uncured state or cured at below 60 ° C.
  • sealants are materials in accordance with DIN EN 26927, in particular those which harden plastically or elastically as sealants.
  • the sealants according to the invention can contain all additives typical of the corresponding sealants, such as typical thickeners, reinforcing fillers, crosslinkers, crosslinking catalysts, pigments, adhesives or other volume extenders.
  • Sealants containing patchouii oil, patchouli alcohol and / or its derivatives can by Dispersing in a manner known to the person skilled in the art, for example through the use of dispersing devices, kneaders, planetary mixers, etc., with the exclusion of moisture and oxygen, can be incorporated both into the finished and into parts of these sealing compounds or together with one or more components of the sealing compounds.
  • Sealants which can be used according to the invention can be produced both on a silicone, urethane and acrylic basis.
  • Urethane-based sealants are disclosed, for example, in Ullmann's Encyclopedia of Industrial Chemistry (8th edition 2003, chapter 4) and US 4,417,042.
  • Silicone sealants are known to the person skilled in the art, for example from EP 0 118 030 A, EP 0 316 591 A, EP 0 327 847 A, EP 0 553 143 A, DE 195 49 425 A and US 4,417,042.
  • acrylic sealants examples include disclosed in WO 01/09249 or US 5,077,360.
  • So-called one-component systems are particularly preferred, which contain all the ingredients for building up a sealing compound, with the conclusion of Humidity and / or atmospheric oxygen are stored and cured at the place of use in reaction with the atmospheric oxygen.
  • the so-called silicone neutral systems are particularly preferred, in which the reaction of crosslinkers with the water in the ambient air does not lead to corrosive, acidic, basic or odor-intensive fission products. Examples of such systems are disclosed in DE 19549 425, US 4,417,042 or EP 0 327 847.
  • the sealing compounds and in particular joint sealing compounds can contain aqueous or organic solvents.
  • Suitable organic solvents are hydrocarbons such as cyclohexane, toluene or else xylene or petroleum ether.
  • Other solvents are ketones such as methyl butyl ketone or chlorinated hydrocarbons.
  • the sealants may also contain other rubber-like polymers.
  • Relatively low molecular weight, commercially available types of polyisobutylene, polyisoprene or polybutadiene styrene can be used here. It is also possible to use dismantled natural rubber or neoprene rubber. Flowable types, which are often referred to as "liquid rubber", can also be used here at room temperature.
  • the sealing compounds according to the invention can be used to connect or seal the most diverse materials together. It is primarily intended for use on concrete, glass, plaster and / or enamel as well as ceramic and porcelain. But it is also possible to connect or seal molded parts or profiles made of aluminum, steel, zinc or plastics such as PVC or polyurethane or acrylic resins. Finally, the sealing of wood or wood materials with various other materials should be mentioned.
  • the stability of joint sealants is usually achieved by adding fine-particle solids - also called fillers.
  • fillers can be divided into organic and inorganic types. Silica / silicon dioxide, for example, can be used as inorganic fillers (coated or uncoated), chalk - coated or uncoated - and / or zeolites are preferred. The latter can also act as desiccants.
  • organic filler comes e.g. B. PVC powder into consideration.
  • the fillers generally make a significant contribution to the sealing compound having a necessary internal hold after use, so that the sealing compound is prevented from leaking or bulging out of vertical joints.
  • the additives or fillers mentioned can be divided into pigments and thixotropic fillers, also abbreviated as thixotropic agents.
  • Suitable thixotropic agents are the known thixotropic agents such as bentones, kaolins or organic compounds such as hydrogenated castor oil or derivatives thereof with polyfunctional amines, or the reaction products of stearic acid or ricinoleic acid with ethylenediamine.
  • the use of silica, in particular silica from pyrolysis, has proven to be particularly favorable.
  • Also suitable as thixotropic agents are essentially swellable polymer powders. Examples include polyacrylonitrile, polyurethane, polyvinyl chloride, polyacrylic acid esters,
  • polyvinyl alcohols polyvinyl acetates and the corresponding copolymers. Particularly good results can be obtained with fine-particle polyvinyl chloride powder.
  • adhesion promoters such as mercaptoalkylsilane can also be used.
  • mercaptoalkyl trialkoxysilane it has proven to be advantageous to use a monomer captoalkyl trialkoxysilane.
  • mercaptopropyltrimethoxysilane is commercially available.
  • the properties of a joint sealant can be further improved if additional components are added to the plastic powder used as a thixotropic agent. These are substances that fall under the category of plasticizers or swelling agents and swelling aids used for plastics.
  • plasticizers in particular for the sealing compounds based on urethane or acrylic from the class of phthalic acid into consideration.
  • Examples of applicable compounds from this class of substances are Dioctyl phthalate, dibutyl phthalate and benzyl butyl phthalate.
  • Other suitable classes of substances are chlorinated paraffins, alkyl sulfonic acid esters, such as phenols or cresols, and fatty acid esters.
  • silicone sealants as a plasticizer are silicone oils, particularly preferably polydimethylsiloxanes, as well as hydrocarbons and / or mixtures thereof, of which particularly hydrocarbons or mixtures thereof having a boiling point of greater than 200 0 C, in particular above 230 0 C is well suited.
  • Such low molecular weight organic substances which are miscible with the polymer powder and the plasticizer can be used as swelling aids.
  • swelling aids can be found in the relevant plastic and polymer manuals for the person skilled in the art.
  • Esters, ketones, aliphatic hydrocarbons, aromatic hydrocarbons and aromatic hydrocarbons with alkyl substituents serve as preferred swelling auxiliaries for polyvinyl chloride powder.
  • the pigments and dyes used are the substances known for these purposes, such as titanium dioxide, iron oxides and carbon black
  • stabilizers such as benzoyl chloride, acetyl chloride, toluenesulfonic acid methyl ester, carbodiimides and / or polycarbodiimides are added to the sealants to improve the storage stability.
  • Olefins with 8 to 20 carbon atoms have proven to be particularly good stabilizers. In addition to the stabilizing effect, these can also perform plasticizer or swelling agent functions. Olefins having 8 to 18 carbon atoms are preferred, in particular if the double bond is arranged in the 1,2 position. The best results are obtained if the molecular structure of these stabilizers is linear.
  • patchouli oil, patchouli alcohol and / or its derivatives to reduce the adherence of microorganisms, in particular mold, to surfaces, and to asexual ones Propagation of fungi, especially mold, avoids the problem of resistance formation due to biocidal agents.
  • mold-prone building and construction aids especially in adhesives, paints and sealants, particularly preferably in joint sealants, several desired effects are achieved by reducing the adhesion of mold to surfaces or by inhibiting spore formation:
  • wallpaper adhesives containing 0.000001 to 3% by weight of patchouli oil, patchouli alcohol and / or derivatives thereof.
  • Wallpaper paste from aqueous solutions of hydrocolloids such as methyl cellulose, methyl hydroxypropyl cellulose or water-soluble starch derivatives.
  • Aqueous dispersions of film-forming high molecular weight, such as polyvinyl acetate, can also be used, in particular in conjunction with the cellulose and starch derivatives already mentioned.
  • filter media All known types can be used as filter media as long as they are suitable for use in water or air filter systems, in particular for air conditioning systems or room humidifiers.
  • filter materials made of cellulose, glass fibers, PVC fibers, polyester fibers, polyamide fibers, in particular nylon fibers, nonwovens, sintered materials and membrane filters are to be mentioned.
  • the concentration of the patchouli oil, patchouli alcohol and / or its derivatives to be used to reduce the adhesion of microorganisms to surfaces in the agents according to the invention can be varied within a wide range by the person skilled in the art, depending on the conditions of use of the agents.
  • the agents according to the invention are produced according to customary recipes known to those skilled in the art. Patchouli oil, patchouli alcohol and / or its derivatives are preferably added to the already prepared agents, but they can also be added during the manufacturing process if so desired.
  • Another object of the invention is a cosmetic composition containing 0.000001 to 3 wt .-% of patchouli oil, patchouli alcohol and / or its derivatives, in particular for reducing the adhesion of microorganisms.
  • These agents preferably contain 0.00001 to 1.0% by weight, in particular 0.0001 to 0.1% by weight and very particularly preferably 0.0001 to 0.05% by weight of patchouli oil, patchouli alcohol and / or a mixture thereof derivatives.
  • the composition is an agent for oral, dental or dental prosthesis care.
  • yeasts in particular those of the genus Candrola
  • bacteria of the genus Streptococcus in particular S. grodonii, S. mutans
  • Actino myces in particular A. naeslundii, Neisseria and Haemophilus, and all of Paster et al., J. Bac. 183 (12), 2001, pp. 3770-3783 relevant for oral hygiene.
  • partial dentures or dentures they are suitable for use as denture cleaning tablets, as mouthwash or mouthwash, or as toothpaste.
  • the mouth, tooth and / or denture care products according to the invention can be present, for example, as mouthwash, gel, liquid toothbrush lotion, stiff toothpaste, denture cleaner or denture adhesive cream.
  • a suitable carrier for example, which contain 0 to 15% by weight of ethanol, 1 to 1.5% by weight of aromatic oils and 0.01 to 0.5% by weight of sweeteners or mouthwashes as mouthwash concentrates may contain 15 to 60% by weight of ethanol, 0.05 to 5% by weight of aromatic oils, 0.1 to 3% by weight of sweeteners and, if appropriate, further auxiliaries and may be diluted with water before use.
  • the concentration of the components must be chosen so high that the dilution does not fall below the specified concentration limits after use.
  • gels and more or less flowable pastes can also serve as carriers, which are expressed from flexible plastic containers or tubes and applied to the teeth with the aid of a toothbrush.
  • Such products contain higher amounts of humectants and binders or consistency regulators and polishing components.
  • these preparations also contain aromatic oils, sweeteners and water.
  • humectants e.g. Glycerin, sorbitol, xylitol, propylene glycols, polyethylene glycols or mixtures of these polyols, in particular those polyethylene glycols with molecular weights from 200 to 800 (from 400 to 2000) can be used.
  • Sorbitol is preferably present as a humectant in an amount of 25-40% by weight.
  • Condensed phosphates in the form of their alkali metal salts can be present as anti-tartar active ingredients and as demineralization inhibitors.
  • the aqueous solutions of these phosphates are alkaline due to hydrolytic effects.
  • the pH of the oral, dental and / or denture care products according to the invention is adjusted to the preferred values of 7.5-9.
  • Mixtures of different condensed phosphates or hydrated salts of the condensed phosphates can also be used. However, the specified amounts of 2-12% by weight refer to the anhydrous salts.
  • a sodium or is preferred as the condensed phosphate Potassium tripolyphosphate in an amount of 5 - 10 wt .-% of the composition.
  • a preferably contained active ingredient is a caries-inhibiting fluorine compound, preferably from the group of fluorides or monofluorophosphates in an amount of 0.1-0.5% by weight of fluorine.
  • Suitable fluorine compounds are, for example, sodium monofluorophosphate (Na 2 PO 3 F), potassium monofluorophosphate, sodium or potassium fluoride, tin fluoride or the fluoride of an organic amino compound.
  • Natural and synthetic water-soluble polymers such as carrageenan, tragacanth, guar, starch and their non-ionic derivatives such as hydroxypropyl guar, hydroxyethyl starch, cellulose ethers such as hydroxyethyl cellulose or methyl hydroxypropyl cellulose are used as binders and consistency regulators.
  • Other substances that are suitable for viscosity control are layered silicates such as, for example, montmorillonite clays, colloidal thickening silicas, for example airgel silica or pyrogenic silicas.
  • polishing components may all heretofore known polishing agent, but preferably precipitated and gel silicas, aluminum hydroxide, aluminum silicate, alumina, alumina trihydrate, insoluble sodium metaphosphate, calcium pyrophosphate, calcium hydrogen phosphate, dicalcium phosphate, chalk, hydroxyapatite, hydrotalcites, talc, magnesium aluminum silicate (Veegum ®), calcium sulfate, magnesium carbonate, Magnesium oxide, sodium aluminum silicates, for example zeolite A or organic polymers, for example polymethacrylate, can be used.
  • the polishing agents are preferably used in smaller amounts, for example 1-10% by weight.
  • the dental and / or oral care products according to the invention can be added to their organoleptic by adding aromatic oils and sweeteners Properties are improved. All natural and synthetic aromas customary for mouth, tooth and / or denture care products are suitable as aroma oils. Natural flavors can be used both in the form of the essential oils isolated from the drugs and in the individual components isolated from them. At least one aromatic oil from the group peppermint oil, spearmint oil, anise oil, caraway oil, eucalyptus oil, fennel oil, cinnamon oil, geranium oil, sage oil, thyme oil, marjoram oil, basil oil, citrus oil, Gaultheria oil or one or more synthetically produced components of these oils isolated therefrom.
  • oils mentioned are, for example, menthol, carvone, anethole, cineol, eugenol, cinnamaldehyde, geraniol, citronellol, linalool, salves, thymol, terpinene, terpinol, methylchavicol and methyl salicylate.
  • suitable flavors are, for example, menthyl acetate, vanillin, jonone, linalyl acetate, rhodinol and piperiton.
  • Either natural sugars such as sucrose, maltose, lactose and fructose or synthetic sweeteners such as saccharin sodium salt, sodium cyclamate or aspartame are suitable as sweeteners.
  • alkyl and / or alkenyl (oligo) glycosides can be used as surfactants.
  • Their preparation and use as surface-active substances are, for example, from US-A-3 839 318, US-A-3 707 535, US-A-3 547 828 DE-A-19 43 689, DE-A-20 36 472 and DE -A-30 01 064 and EP-A-77 167 known.
  • the degree of oligomerization is a statistical mean value which is based on a homolog distribution customary for such technical products.
  • An alkyl and / or alkenyl (oligo) glycoside is preferably an alkyl and / or alkenyl (oligo) glucoside of the formula RO (C 6 Hi 0 O) x -H, in which R is an alkyl and / or alkenyl group with 8 to 14 carbon atoms and x has an average value of 1 to 4.
  • Particularly preferred are alkyl oligoglucosides based on hydrogenated C 12/14 coconut oil alcohol having a DP of 1 to 3.
  • the alkyl and / or alkenyl Glycoside surfactant can be used very sparingly, quantities from 0.005 to 1% by weight being sufficient.
  • non-ionic, ampholytic and cationic surfactants may also be present, such as: fatty alcohol polyglycol ether sulfates, monoglyceride sulfates, monoglyceride ether sulfates, mono- and / or dialkyl sulfosuccinates, fatty acid isethionates, fatty acid seguric acid amides, fatty acid segaramidates, fatty acid seguric acid amides, fatty acid seguramides, fatty acid segasuronamides, fatty acid seguramides, fatty acid segasuronamides, fatty acid seguramides, fatty acid segasuronamides, fatty acid segasuronamides, fatty acid segasuronamides, fatty acid segasuronamides, fatty acid segasuronamides, fatty acid segasuronamides, fatty acid segarosuramides, fatty acid segasuronamides, fatty acid segarosinate
  • a nonionic solubilizer from the group of surface-active compounds may be required.
  • Particularly suitable for this purpose are, for example, ethoxylated fatty acid glycerides, ethoxylated fatty acid sorbitan partial esters or fatty acid partial esters of glycerol or sorbitan oxethylates.
  • Solubilizers from the group of the ethoxylated fatty acid glycerides mainly include addition products of 20 to 60 mol ethylene oxide with mono- and diglycerides of linear fatty acids with 12 to 18 carbon atoms or with triglycerides of hydroxy fatty acids such as oxystearic acid or ricinoleic acid.
  • Other suitable solubilizers are ethoxylated fatty acid sorbitan partial esters; these are preferably addition products of 20 to 60 mol of ethylene oxide with sorbitan monoesters and sorbitan diesters of fatty acids with 12 to 18 carbon atoms.
  • solubilizers are fatty acid partial esters of glycerol or sorbitan oxyethylates; these are preferably mono- and diesters of Ci 2 -Ci 8 fatty acids and addition products of 20 to 60 moles of ethylene oxide with 1 mole of glycerol or with 1 mole of sorbitol.
  • the oral, dental and / or denture care agents according to the invention preferably contain adducts of 20 to 60 mol ethylene oxide with hardened or unhardened castor oil (ie with oxystearic acid or ricinoleic acid triglyceride), with glycerol mono- and / or as a solubilizer for aromatic oils which may be present -distearate or sorbitan mono- and / or -distearate.
  • Other common additives for mouth, tooth and / or denture care agents are, for example
  • Pigments e.g. Titanium dioxide, and / or dyes, pH adjusting agents and buffer substances such as sodium bicarbonate,
  • Salts for example NaH 2 PO 4 wound healing and anti-inflammatory substances such as allantoin,
  • Urea, panthenol, azulene or chamomile extract, other substances effective against tartar e.g. Organophosphonates, e.g.
  • Preservatives such as Sorbic acid salts, p-hydroxybenzoic acid
  • Plaque inhibitors such as Hexachlorophene, chlorhexidine, hexetidine,
  • Triclosan, bromochlorophene, phenylsalicylic acid ester Triclosan, bromochlorophene, phenylsalicylic acid ester.
  • the composition is a mouthwash, a mouthwash, a denture cleaner or a denture adhesive.
  • compositions are used either undiluted or as a concentrate.
  • the concentrates and the prosthesis cleaners therefore preferably contain, in addition to the usual constituents, preferably 0.001 to 1, in particular 0.001 to 0.5, and very particularly preferably 0.005 to 0.1% by weight and the mouthwashes and denture adhesives to be used undiluted, preferably 0.0001 to 0, 5, in particular 0.0001 to 0.1, and very particularly preferably 0.0001 to 0.05% by weight of patchouli oil, patchouli alcohol and / or its derivatives.
  • Per-compounds such as peroxoborate, peroxomonosulfate or percarbonate are also suitable for denture cleaners preferred according to the invention, in particular denture cleaning tablets and powder, in addition to the ingredients already mentioned for mouth, tooth and / or denture care. They have the advantage that they have a deodorising and / or disinfecting effect in addition to the bleaching effect.
  • the use of such per compounds in prosthesis cleaners is between 0.01 and 10% by weight, in particular between 0.5 and 5% by weight.
  • Enzymes such as e.g. Proteases and carbohydrase, suitable for breaking down proteins and carbohydrates.
  • the pH can be between pH 4 and pH 12, in particular between pH 5 and pH 11.
  • auxiliary substances are also required for the prosthesis cleaning tablets, such as, for example, agents which produce a bubbling effect, such as, for example, CO 2 -releasing substances such as sodium bicarbonate, fillers, for example sodium sulfate or dextrose, lubricants, for example magnesium stearate, flow regulating agents, for example colloidal silicon dioxide and granulating agents. like the already mentioned high molecular weight polyethylene glycols or polyvinyl pyrrolidone.
  • agents which produce a bubbling effect such as, for example, CO 2 -releasing substances such as sodium bicarbonate, fillers, for example sodium sulfate or dextrose, lubricants, for example magnesium stearate, flow regulating agents, for example colloidal silicon dioxide and granulating agents.
  • CO 2 -releasing substances such as sodium bicarbonate
  • fillers for example sodium sulfate or dextrose
  • lubricants for example magnesium stearate
  • flow regulating agents for example colloidal silicon dioxide
  • Denture adhesives can be offered as powders, creams, foils or liquids and support the adhesion of the dentures.
  • Natural and synthetic swelling agents are suitable as active ingredients. As a natural
  • swelling substances are also plant gums, e.g. Gum arabic, tragacanth and karaya gum as well as natural rubber.
  • alginates and synthetic swelling agents e.g.
  • Hydrophobic bases in particular hydrocarbons such as, for example, are particularly suitable as auxiliaries for pasty and liquid products
  • DAB White petroleum jelly
  • paraffin oil paraffin oil
  • the present invention furthermore relates to cosmetics, in particular personal care products, which contain patchouli oil, patchouli alcohol and / or its derivatives to reduce the adhesion of microorganisms, in particular fungi, particularly preferably keratinophilic fungi, such as, for example, hair shampoos, hair lotions, foam baths, shower baths, foot baths, creams, gels, lotions, alcoholic and aqueous / alcoholic solutions, emulsions, wax / fat masses, stick preparations, powders or ointments can be used as auxiliaries and additives, mild surfactants, oil bodies, emulsifiers, superfatting agents, pearlescent waxes, consistency agents, thickeners , Polymers, silicone compounds, fats, waxes, stabilizers, biogenic active substances, deodorants, antiperspirants, antidandruff agents, film formers, swelling agents, UV light protection factors, antioxidants, hydrotropes, preservatives, insect repellents, self-
  • the cosmetic preparation is selected from personal care products, in particular creams, lotions, gels (in particular also for hands and / or feet), shower, foam and / or foot baths - and hair treatment products, in particular hair shampoos, hair lotions and hair care products.
  • personal care products in particular creams, lotions, gels (in particular also for hands and / or feet), shower, foam and / or foot baths - and hair treatment products, in particular hair shampoos, hair lotions and hair care products.
  • patchouli oil, patchouli alcohol and / or its derivatives in cosmetic preparations can preferably reduce the adhesion of microorganisms, preferably fungi, in particular keratinophilic fungi, to skin, in particular human skin.
  • the development of an infection of the skin or the cornea and the appendages of the skin can be prevented particularly well by using the cosmetic agents according to the invention.
  • the adherence to and thus also the increase in particular of keratinophilic fungi in the skin and nails can be prevented by the lotions and skin creams according to the invention, in particular also for hands and nails, without having to additionally use antimicrobial substances. Secondary infections of such already damaged skin areas, in particular by bacteria, can also be prevented in this way.
  • hair treatment agents preferably hair shampoos or hair lotions and hair care products such as Hair treatments, preferably against dandruff
  • hair care products such as Hair treatments, preferably against dandruff
  • Suitable mild, i.e. surfactants that are particularly compatible with the skin are fatty alcohol polyglycol ether sulfates, monoglyceride sulfates, mono- and / or dialkyl sulfosuccinates, fatty acid isethionates, fatty acid sarcosinates,
  • Fatty acid aurides Fatty acid glutamates, ⁇ -olefin sulfonates, ether carboxylic acids, alkyl oligoglucosides, fatty acid glucamides, alkyl amido betaines and / or protein fatty acid condensates, the latter preferably based on wheat proteins.
  • Guerbet alcohols based on fatty alcohols having 6 to 18, preferably 8 to 10 carbon atoms, esters of linear C 6 -C 22 fatty acids with linear C 6 -C 22 fatty alcohols, esters of branched C 6 -Ci 3 carboxylic acids are, for example, oil bodies with linear C 6 -C 22 -fatty alcohols, such as myristyl myristate, myristyl palmitate, myristyl stearate, Myristylisostearat, myristyl, Myristylbehenat, Myristylerucat, cetyl myristate, cetyl palmitate, cetyl stearate, Cetylisostearat, cetyl oleate, cetyl behenate, Cetylerucat, Stearylmyristat, stearyl palmitate, stearyl stearate, Stearylisostearat, stearyl oleate, stearyl behenate, Ste
  • esters of linear C 6 -C 22 fatty acids with branched alcohols are suitable especially dioctyl malates, esters of linear and / or branched fatty acids with polyhydric alcohols (such as propylene glycol, dimer diol or trimer triol) and / or Guerbet alcohols, triglycerides based on C 6 -Cio fatty acids, liquid mono- / di- / triglyceride mixtures based on C 6 -C 8 fatty acids, esters of C 6 -C 22 fatty alcohols and / or Guerbet alcohols with aromatic carboxylic acids, in particular benzoic acid, esters of C 2 -C 2 dicarboxylic acids with linear or branched alcohols with 1 to 22 carbon atoms or polyols with 2 to 10 carbon atoms and 2 to 6 hydroxyl groups,
  • Finsolv® TN linear or branched, symmetrical or asymmetrical dialkyl ethers with 6 to 22 carbon atoms per alkyl group, Ring opening products of epoxidized fatty acid esters with polyols, silicone oils and / or aliphatic or naphthenic hydrocarbons, such as, for example, squalane, squalene or dialkylcyclohexanes.
  • Suitable emulsifiers are, for example, nonionic surfactants from at least one of the following groups:
  • partial esters based on linear, branched, unsaturated or saturated C6 / 22 fatty acids, ricinoleic acid and 12-hydroxystearic acid and glycerol, Polyglycerol, pentaerythritol, dipentaerythritol, sugar alcohols (eg sorbitol), alkyl glucosides (eg methyl glucoside, butyl glucoside, lauryl glucoside) and polyglucosides (eg cellulose);
  • the adducts of ethylene oxide and / or of propylene oxide with fatty alcohols, fatty acids, alkylphenols, glycerol mono- and diesters and sorbitan mono- and diesters of fatty acids or with castor oil are known, commercially available products. These are mixtures of homologs, the middle of which Degree of alkoxylation corresponds to the ratio of the amounts of ethylene oxide and / or propylene oxide and substrate with which the addition reaction is carried out. 12 C / i 8 fatty acid monoesters and diesters of addition products of ethylene oxide onto glycerol are known from DE 2024051 as refatting agents for cosmetic preparations.
  • Alkyl and / or alkenyl mono- and oligoglycosides their preparation and their use are known from the prior art. They are produced in particular by reacting glucose or oligosaccharides with primary alcohols with 8 to 18 carbon atoms.
  • glycoside residue both monoglycosides in which a cyclic sugar residue is glycosidically bonded to the fatty alcohol and oligomeric glycosides with a degree of oligomerization of up to preferably about 8 are suitable.
  • the degree of oligomerization is a statistical mean value which is based on a homolog distribution customary for such technical products.
  • polyglycerol esters are polyglyceryl-2 dipolyhydroxystearate (Dehymuls® PGPH), polyglycerol-3 diisostearate (Lameform® TGI), polyglyceryl-4 isostearate (Isolan® Gl 34), polyglyceryl-3 oleate, diisostearoyl polyglyceryl-3 diisostearate ® PDI), Polyglyceryl-3 Methylglucose Distearate (Tego Gare® 450), Polyglyceryl-3 Beeswax (Gera Bellina®), Polyglyceryl-4 Caprate (Polyglycerol Caprate T2010 / 90), Polyglyceryl-3 Cetyl Ether (Chimexane® NL), Polyglyceryl -3 Distearate (Cremophor® GS 32) and Polyglyceryl Polyricinoleate (Admul® WOL 1403) Polyglyceryl Dimerate Isostear
  • Zwitterionic surfactants can also be used as emulsifiers.
  • Zwitterionic surfactants are surface-active compounds that contain at least one quaternary ammonium group and at least one carboxylate and one sulfonate group in the molecule.
  • Particularly suitable zwitterionic surfactants are the so-called betaines such as the N-alkyl-N, N-dimethylammonium glycinates, for example that
  • the fatty acid amide derivative known under the CTFA name Cocamidopropyl Betaine is particularly preferred.
  • Suitable emulsifiers are ampholytic surfactants.
  • Ampholytic surfactants are surface-active compounds which, in addition to a Ce / i ⁇ -alkyl or - acyl group, contain at least one free amino group and at least one - COOH or -SO 3 H group in the molecule and are capable of forming internal salts.
  • ampholytic surfactants are N-alkylglycine, N-alkylpropionic acid, N-alkylaminobutyric acid, N-alkyliminodipropionic acid, N-hydroxyethyl-N-alkylamidopropylglycine, N-alkyltaurine, N-alkyl sarcosine, 2-alkyl amino propionic acid and alkyl amino acetic acid each about 8 to 18 carbon atoms in the alkyl group.
  • ampholytic surfactants N-cocoalkylaminopropionate, the cocoacylaminoethylaminopropionate and that
  • ampholytic emulsifiers quaternary emulsifiers are also suitable, those of the esterquat type, preferably methylquaternized difatty acid triethanolamine ester salts, being particularly preferred.
  • Substances such as lanolin and lecithin and polyethoxylated or acylated lanolin and lecithin derivatives, polyol fatty acid esters, monoglycerides and fatty acid alkanolamides can be used as superfatting agents, the latter simultaneously serving as foam stabilizers.
  • Pearlescent waxes that can be used are, for example: alkylene glycol esters, especially ethylene glycol distearate; Fatty acid alkanolamides, especially
  • coconut fatty acid diethanolamide Partial glycerides, especially stearic acid monoglyceride; Esters of polyvalent, optionally hydroxy-substituted carboxylic acids with fatty alcohols having 6 to 22 carbon atoms, especially long-chain esters of tartaric acid; Fatty substances, such as, for example, fatty alcohols, fatty ketones, fatty aldehydes, fatty ethers and fatty carbonates, which have a total of at least 24 carbon atoms, especially lauron and distearyl ether; Fatty acids such as stearic acid, hydroxystearic acid or behenic acid, ring opening products of olefin epoxides with 12 to 22 carbon atoms with fatty alcohols with 12 to 22 carbon atoms and / or polyols with 2 to 15 carbon atoms and 2 to 10 hydroxyl groups and mixtures thereof.
  • Fatty substances such as, for example, fatty alcohols, fatty ketones, fatty aldehy
  • Suitable consistency agents are primarily fatty alcohols or hydroxyfatty alcohols with 12 to 22 and preferably 16 to 18 carbon atoms and also partial glycerides, fatty acids or hydroxyfatty acids. A combination of these substances with alkyl oligoglucosides and / or fatty acid N-methylglucamides of the same chain length and / or polyglycerol poly-12-hydroxystearates is preferred.
  • Suitable thickeners are, for example, Aerosil types (hydrophilic silicas), polysaccharides, in particular xanthan gum, guar guar, agar Agar, alginates and tyloses, carboxymethyl cellulose and hydroxyethyl cellulose, also higher molecular weight polyethylene glycol mono- and diesters of fatty acids, polyacrylates (e.g.
  • surfactants such as ethoxylated fatty acid glycerides, fatty acid glycerides with polyols such as pentaerythritol or trimethyloipropan, fatty alcohol ethoxylates with a narrow homolog distribution or alkyl oligoglucosides and electrolytes such as sodium chloride and ammonium chloride.
  • Suitable cationic polymers are, for example, cationic cellulose derivatives, e.g. a quaternized hydroxyethyl cellulose available under the name Polymer JR 400® from Amerchol, cationic starch, copolymers of diallylammonium salts and acrylamides, quaternized vinylpyrrolidone / vinylimidazole polymers such as e.g.
  • Luviquat® condensation products of polyglycols and amines, quaternized collagen polypeptides such as lauryldimonium hydroxypropyl hydrolyzed collagen (Lamequat®l_ / Grünau), quaternized wheat polypeptides, polyethyleneimine, cationic silicone polymers, such as e.g. Amidethethicones, copolymers of adipic acid and dimethylaminohydroxypropyldiethylenetriamine (Cartaretine® / Sandoz), copolymers of acrylic acid with dimethyldiallylammonium chloride (Merquat® 550 / Chemviron), polyaminopolyamides, e.g.
  • cationic chitin derivatives such as quaternized chitosan, optionally microcrystalline, condensation products from dihaloalkylene, such as e.g. Dibromobutane with bisdialkylamines, e.g. Bis-dimethylamino-1, 3-propane, cationic guar gum, e.g. Jaguar® CBS, Jaguar® C-17, Jaguar® C-16 from Celanese, quaternized ammonium salt polymers, e.g. Mirapol® A-15, Mirapol® AD-1, Mirapol® AZ-1 from Miranol.
  • dihaloalkylene such as e.g. Dibromobutane with bisdialkylamines, e.g. Bis-dimethylamino-1, 3-propane
  • cationic guar gum e.g. Jaguar® CBS, Jaguar® C-17, Jaguar® C-16 from Celanese
  • quaternized ammonium salt polymers e.g. Mirapol® A
  • anionic, zwitterionic, amphoteric and nonionic polymers are vinyl acetate / crotonic acid copolymers, vinylpyrrolidone / vinyl acrylate copolymers, vinyl acetate / butyl maleate / isobornyl acrylate copolymers, Methyl vinyl ether / maleic anhydride copolymers and their esters, uncrosslinked and polyols crosslinked polyacrylic acids, acrylamidopropyltrimethylammonium chloride / acrylate copolymers, octylacrylamide / methyl methacrylate / tert.butylaminoethyl methacrylate / 2-hydroxypropyl methacrylate copolymers, polyvinyl pyrrolidone, polyvinyl pyrrolidone, polyvinyl pyrrolidone, polyvinyl pyrrolidone Vinylpyrrolidone / dimethylaminoethyl
  • Suitable silicone compounds are, for example, dimethylpolysiloxanes, methylphenylpolysiloxanes, cyclic silicones and amino-, fatty acid-, alcohol-, polyether-, epoxy-, fluorine-, glycoside- and / or alkyl-modified silicone compounds which can be both liquid and resinous at room temperature.
  • Simethicones which are mixtures of dimethicones with an average chain length of 200 to 300 dimethylsiloxane units and hydrogenated silicates, are also suitable.
  • a detailed overview of suitable volatile silicones can also be found by Todd et al. in Cosm.Toil. 9i, 27 (1976).
  • fats are glycerides
  • waxes include natural waxes such as Candelilla wax, carnauba wax, japan wax, esparto grass wax, cork wax, guaruma wax, rice-germ oil wax, sugar cane wax, ouricury wax, montan wax, beeswax, shellac wax, walnut, lanolin (wool wax), pretzel fat, ceresin, ozokerite (earth wax), petrolatum, paraffin waxes chemically modified waxes (hard waxes), e.g. Montanester waxes, Sasol waxes, hydrogenated jojoba waxes and synthetic waxes, such as Polyalkylene waxes and polyethylene glycol waxes in question.
  • natural waxes such as Candelilla wax, carnauba wax, japan wax, esparto grass wax, cork wax, guaruma wax, rice-germ oil wax
  • sugar cane wax ouricury wax
  • Metal salts of fatty acids such as e.g. Magnesium, aluminum and / or zinc stearate or ricinoleate can be used.
  • biogenic active ingredients are tocopherol, tocopherol acetate, tocopherol palmitate, ascorbic acid, deoxyribonucleic acid, retinol, bisabolol, To understand allantoin, phytantriol, panthenol, AHA acids, amino acids, ceramides, pseudoceramides, essential oils, plant extracts and vitamin complexes.
  • Cosmetic deodorants counteract, mask or eliminate body odors.
  • Body odors arise from the action of skin bacteria on apocrine sweat, whereby unpleasant smelling breakdown products are formed. Accordingly, deodorants contain active ingredients that act as germ inhibitors, enzyme inhibitors, odor absorbers or odor maskers.
  • germ-inhibiting agents which can optionally be added to the cosmetics according to the invention in addition to the patchouli oil, patchouli alcohol and / or its derivatives used to inhibit the adhesion of microorganisms, all substances which are effective against gram-positive bacteria are suitable in principle, such as, for. B.
  • Enzyme inhibitors can also be added to the cosmetics according to the invention.
  • esterase inhibitors may be suitable enzyme inhibitors.
  • These are preferably trialkyl citrates such as trimethyl citrate, tripropyl citrate, triisopropyl citrate, tributyl citrate and in particular triethyl citrate (Hydagen® CAT, Henkel KGaA, Düsseldorf / FRG).
  • the substances inhibit enzyme activity and thereby reduce odor.
  • esterase inhibitors are sterolsulfates or - phosphates, such as, for example, lanosterol, cholesterol, campesterol, Stigmasterol and sitosterol sulfate phosphate or, dicarboxylic acids and esters thereof such as glutaric acid, monoethyl glutarate, diethyl glutarate, adipic acid, adipic acid monoethyl ester, adipic rediethylester, malonic acid and diethyl malonate, hydroxycarboxylic acids and esters thereof such as citric acid, malic acid, tartaric acid or diethyl tartrate, and zinc glycinate.
  • dicarboxylic acids and esters thereof such as glutaric acid, monoethyl glutarate, diethyl glutarate, adipic acid, adipic acid monoethyl ester, adipic rediethylester, malonic acid and diethyl malonate,
  • Suitable as odor absorbers are substances which absorb odor-forming compounds and can retain them to a large extent. They lower the partial pressure of the individual components and thus also reduce their speed of propagation. It is important that perfumes must remain unaffected. Odor absorbers are not effective against bacteria. They contain, for example, a complex zinc salt of ricinoleic acid or special, largely odorless fragrances, which are known to the person skilled in the art as "fixers", such as, for example, the main component. B. extracts of Labdanum or Styrax or certain abietic acid derivatives. Fragrance agents or perfume oils act as odor maskers and, in addition to their function as odor maskers, give the deodorants their respective fragrance.
  • Perfume oils include, for example, mixtures of natural and synthetic fragrances. Natural fragrances are extracts of flowers, stems and leaves, fruits, fruit peels, roots, woods, herbs and grasses, needles and branches as well as resins and balms. Animal raw materials, such as civet and castoreum, are also suitable. Typical synthetic fragrance compounds are products of the ester, ether, aldehyde, ketone, alcohol and hydrocarbon type.
  • Antiperspirants reduce sweat formation by influencing the activity of the eccrine sweat glands and thus counteract armpit wetness and body odor.
  • Aqueous or anhydrous formulations of antiperspirants typically contain the following ingredients:
  • auxiliaries such as B. thickeners or complexing agents and / or
  • non-aqueous solvents such as e.g. As ethanol, propylene glycol and / or glycerin.
  • Salts of aluminum, zirconium or zinc are particularly suitable as astringent antiperspirant active ingredients.
  • suitable antiperspirant active ingredients are e.g. Aluminum chloride, aluminum chlorohydrate, aluminum dichlorohydrate, aluminum sesquichlorohydrate and their complex compounds z.
  • B. with amino acids such as glycine.
  • oil-soluble and water-soluble auxiliaries can be present in smaller amounts in antiperspirants.
  • oil soluble aids can e.g. his:
  • water-soluble additives are e.g. Preservatives, water-soluble fragrances, pH adjusters, e.g. Buffer mixtures, water soluble thickeners, e.g. water-soluble natural or synthetic polymers such as Xanthan gum, hydroxyethyl cellulose, polyvinyl pyrrolidone or high molecular weight polyethylene oxides.
  • Climbazole, octopirox and zinc pyrethione can be used as antidandruff agents.
  • the preparations according to the invention can preferably be used in combination with at least one of these antidandruff agents.
  • Common film formers are, for example, chitosan, microcrystalline chitosan, quaternized chitosan, polyvinylpyrrolidone, vinylpyrrolidone-vinyl acetate copolymers, polymers of the acrylic acid series, quaternary cellulose derivatives, collagen, hyaluronic acid or its salts and similar compounds.
  • Montmorillonites, clay minerals, pemulene and alkyl-modified carbopol types can serve as swelling agents for aqueous phases. Further suitable polymers or swelling agents can be found in the overview by R. Lochhead in Cosm.Toil. 108, 95 (1993).
  • UV light protection factors are, for example, organic substances (light protection filters) which are liquid or crystalline at room temperature and which are able to absorb ultraviolet rays and absorb the energy in the form of longer-wave radiation, e.g. To give off heat again.
  • UVB filters can be oil-soluble or water-soluble. As oil-soluble substances e.g. to call:
  • 3-benzylidene camphor or 3-benzylidene norcampher and its derivatives e.g. 3- (4-methylbenzylidene) camphor as described in EP 0693471 B1;
  • 4-aminobenzoic acid derivatives preferably 2-ethylhexyl 4-dimethylamino) benzoate, 2-octyl 4- (dimethylamino) benzoate and amyl 4- (dimethylamino) benzoate;
  • Esters of cinnamic acid preferably 4-methoxycinnamic acid 2-ethylhexyl ester, 4-methoxycinnamic acid propyl ester, 4-methoxycinnamic acid isoamyl ester 2-cyano-3,3-phenylcinnamic acid 2-ethylhexyl ester (octocrylene);
  • esters of salicylic acid preferably salicylic acid 2-ethylhexyl ester, salicylic acid 4-isopropylbenzyl ester, salicylic acid homomethyl ester;
  • benzophenone preferably 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone;
  • Esters of benzalmalonic acid preferably di-2-ethylhexyl 4-methoxybenzmalonate; • Triazine derivatives, such as 2, 4,6-trianilino- (p-carbo-2'-ethyl-1 '-hexyloxy) -1, 3,5-triazine and octyl triazone, as described in EP 0818450 A1 or dioctyl butamido Triazone (Uvasorb® HEB);
  • Propane-1,3-dione e.g. 1- (4-tert-butylphenyl) -3-4'methoxyphenyl) propane-1,3-dione;
  • Sulfonic acid derivatives of 3-benzylidene camphor e.g. 4- (2-oxo-3-bornylidene methyl) benzenesulfonic acid and 2-methyl-5- (2-oxo-3-bornylidene) sulfonic acid and their salts.
  • UV-A filters -4'-methoxydibenzoylmethane (Parsol 1789), 1-phenyl-3- (4'-isopropylphenyl) propane-1, 3-dione and enamine compounds as described in DE 19712033 A1 (BASF).
  • the UV-A and UV-B filters can of course also be used in mixtures.
  • insoluble light protection pigments namely finely dispersed metal oxides or salts, are also suitable for this purpose.
  • suitable metal oxides are, in particular, zinc oxide and titanium dioxide and, in addition, oxides of iron, zirconium, silicon, manganese, aluminum and cerium and mixtures thereof.
  • Silicates (talc), barium sulfate or zinc stearate can be used as salts.
  • the oxides and salts are used in the form of the pigments for skin-care and skin-protecting emulsions and decorative cosmetics.
  • the particles should have an average diameter of less than 100 nm, preferably between 5 and 50 nm and in particular between 15 and 30 nm. They can have a spherical shape, but such particles can also are used, which have an ellipsoidal or otherwise deviating from the spherical shape.
  • the pigments can also be surface-treated, ie hydrophilized or hydrophobicized.
  • Typical examples are coated titanium dioxides, such as titanium dioxide T 805 (Degussa) or Eusolex® T2000 (Merck). Silicones, and in particular trialkoxyoctylsilanes or simethicones, are particularly suitable as hydrophobic coating agents. So-called micro- or nanopigments are preferably used in sunscreens. Micronized zinc oxide is preferably used. Further suitable UV light protection filters can be found in the overview by P.Finkel in S ⁇ FW-Journal 122, 543 (1996).
  • secondary light stabilizers of the antioxidant type which interrupt the photochemical reaction chain which is triggered when UV radiation penetrates the skin.
  • Typical examples are amino acids (e.g. glycine, histidine, tyrosine, tryptophan) and their derivatives, imidazoles (e.g. urocanic acid) and their derivatives, peptides such as D, L-carnosine, D-camosine, L-camosine and their derivatives (e.g. anserine) , Carotenoids, carotenes (e.g.
  • ⁇ -carotene, ß-carotene, lycopene) and their derivatives chlorogenic acid and their derivatives, lipoic acid and their derivatives (e.g. dihydroliponic acid), aurothioglucose, propylthiouracil and other thiols (e.g.
  • thioredoxin glutathione, cysteine, cystine, Cystamine and its glycosyl, N-acetyl, methyl, ethyl, propyl, amyl, butyl and lauryl, palmitoyl, oleyl, ⁇ -linoleyl, cholesteryl and glyceryl esters) and their salts, dilauryl thiodipropionate , Distearylthiodipropionate, thiodipropionic acid and their derivatives (esters, ethers, peptides, lipids, nucleotides, nucleosides and salts) as well as sulfoximine compounds (e.g.
  • buthioninsulfoximines homocysteine sulfoximine, butioninsulfones, penta-, hexa-, heptathioninsulfoximine
  • Daily dosages e.g. pmol to ⁇ mol / kg
  • metal chelators e.g. ⁇ -hydroxy fatty acids, palmitic acid, phytic acid, lactoferrin
  • ⁇ -hydroxy acids e.g.
  • citric acid citric acid, lactic acid, malic acid
  • humic acid bile acid, bile extracts, bilirubin, Biliverdin, EDTA, EGTA and their derivatives
  • unsaturated fatty acids and their derivatives eg ⁇ -linolenic acid, linoleic acid, oleic acid
  • folic acid and their derivatives ubiquinone and ubiquinol and their Derivatives
  • vitamin C and derivatives e.g. ascorbyl palmitate, Mg ascorbyl phosphate, ascorbyl acetate
  • tocopherols and derivatives e.g.
  • vitamin E acetate
  • vitamin A and derivatives vitamin A palmitate
  • Hydrotropes such as ethanol, isopropyl alcohol or polyols can also be used to improve the flow behavior.
  • Polyols that come into consideration here preferably have 2 to 15 carbon atoms and at least two hydroxyl groups.
  • the polyols can also contain further functional groups, in particular amino groups, or be modified with nitrogen. Typical examples are
  • Alkylene glycols such as, for example, ethylene glycol, diethylene glycol, propylene glycol, butylene glycol, hexylene glycol and polyethylene glycols with an average molecular weight of 100 to 1,000 daltons;
  • Methyl compounds such as, in particular, trimethylolethane, trimethylolpropane, trimethylolbutane, pentaerythritol and dipentaerythritol;
  • Lower alkyl glucosides in particular those with 1 to 8 carbons in the alkyl radical, such as methyl and butyl glucoside;
  • Sugar alcohols with 5 to 12 carbon atoms such as sorbitol or mannitol, • Sugar with 5 to 12 carbon atoms, such as glucose or sucrose;
  • Aminosugars such as glucamine
  • Dialcohol amines such as diethanolamine or 2-amino-1, 3-propanediol.
  • Suitable preservatives are, for example, phenoxyethanol, formaldehyde solution, parabens, pentanediol or sorbic acid and the other classes of substances listed in Appendix 6, Parts A and B of the Cosmetics Ordinance.
  • N, N-diethyl-m-toluamide, 1, 2-pentanediol or ethyl butylacetylaminopropionate are suitable as insect repellents, and dihydroxyacetone is suitable as a self-tanning agent.
  • Perfume oils include mixtures of natural and synthetic fragrances. Natural fragrances are extracts of flowers (lily, lavender, roses, jasmine, neroli, ylang-ylang), stems and leaves (geranium, petitgrain), fruits (anise, coriander, caraway seeds, juniper), fruit peel (bergamot, lemon, oranges) , Roots (Macis, Angelica, Celery, Cardamom, Costus, Iris, Calmus), Woods (Pine, Sandal, Guaiac, Cedar, Rosewood), Herbs and Grasses (Tarragon, Lemongrass, Sage, Thyme), Needles and Branches (spruce, fir, pine, mountain pine), resins and balsams (galbanum, elemi, benzoin, myrrh, olibanum, opoponax). Animal raw materials, such as civet and castoreum, are also suitable. Typical synthetic fragrance compounds are products of the ester, ether, aldeh
  • the dyes which can be used are the substances which are suitable and approved for cosmetic purposes, as compiled, for example, in the publication "Cosmetic Dyes” by the Dye Commission of the German Research Foundation, Verlag Chemie, Weinheim, 1984, pp. 81-106. These dyes are usually used in concentrations of 0.001 to 0.1% by weight, based on the mixture as a whole.
  • the total proportion of auxiliaries and additives can be 1 to 50, preferably 5 to 40% by weight, based on the composition.
  • the agents can be produced by customary cold or hot processes; the phase inversion temperature method is preferably used.
  • the invention further relates to pharmaceutical preparations for the treatment and / or prophylaxis of infections by microorganisms, preferably by bacteria and / or fungi, in particular by fungi, very particularly preferably by keratinophilic fungi, characterized in that they contain patchouli oil, patchouli alcohol and / or their derivatives contain.
  • these preparations can be applied topically to the skin and its appendages, especially the hair and nails.
  • Infections caused by fungi such as Candida and in particular keratinophilic fungi such as Trichophyton, Microsporum and Epidermophyton (athlete's foot and nail fungus) or Malassezia (Pityriasis versicolor) can be treated in this way by using non-antifungal substances.
  • the preparations according to the invention are also suitable for the prophylaxis of such infections in that the fungi, in particular the keratinophilic fungi, are prevented from settling in the skin (in particular the cornea of the hands and feet) or in the appendages of the skin and multiplying there uninhibitedly. The formation of resistance of these fungi to the usual antifungals is also avoided.
  • Skin areas that are particularly at risk of infection are the scalp, nails, hands and feet, body folds and especially the spaces between the toes and fingers. These infections are also referred to as tinea capitis, tinea unguium, tinea manuurn, tinea pedis and tinea inguinalis.
  • Infections of the skin and mucous membrane, especially in the mouth and in the genital area, by species of the genus Candida, in particular Candida albicans, C. glabrata, C. tropicalis, C. dubliniensis can also be caused by the pharmaceutical preparations according to the invention are treated or prevented.
  • the preparations according to the invention are particularly suitable for the treatment and / or prophylaxis of dermatomycoses which are caused by the keratinophilic fungi, in particular the dermatophytes, and candidiasis which are caused by Candida, in particular Candida albicans.
  • the pharmaceutical preparations preferably contain a physiologically compatible carrier.
  • This comprises one or more adjuvants, as are usually used in such preparations, such as. B. thickeners, moisturizing and / or moisturizing substances, surfactants, emulsifiers, plasticizers, foam retardants, fats, oils, waxes, silicones, sequestering agents, anionic, cationic, nonionic or amphoteric polymers, alkalizing or acidifying agents, alcohols, polyols, softeners, adsorbents , Light stabilizers, electrolytes, organic solvents, preservatives, bactericides, antioxidants, fragrances, flavors, colors and pigments.
  • the pharmaceutical preparations can be in various forms, for example creams or ointments, in particular in anhydrous form, for example an oil or a balm, or else in the form of an oil-in-water or water-in-oil emulsion which can be a cream or milk, for example, in the form of suspensions, solutions, powders or plasters.
  • the carrier can be a vegetable or animal oil, a mineral oil or else a synthetic oil or mixtures of such oils. Patchouli oil and patchouli alcohol are particularly oil-soluble and therefore particularly suitable for incorporation into anhydrous products.
  • the adhesion of keratinophilic fungi to biotic surfaces is reduced.
  • skin and their appendages there are skin and their To understand attachment structures such as hair and / or nails of humans and / or animals.
  • the adhesion of fungi, in particular keratinophilic fungi, to human, biotic surfaces, in particular human skin, is preferably reduced by the use of patchouli oil, patchouli alcohol and / or its derivatives according to the invention.
  • patchouli oil, patchouli alcohol and / or its derivatives according to the invention can also reduce the adhesion of microorganisms, in particular fungi, to animals and the risk of these fungi being transmitted to humans, which may be accompanied by violent inflammatory reactions. The risk of infection can thus be significantly reduced.
  • patchouli oil obtained by steam distillation (mixture of patchouli oil from Kaders, Sensient, Polarome and Nitsche)
  • test specimens were then placed on wort agar plates and covered with a thin layer of agar in which fungal spores (10 5 CFU / ml Aspergillus niger, DSM 1988) were incorporated.
  • the plates were incubated at 25 ° C. for 3 days.
  • the formation of spores over the test specimens was assessed visually and the sporulation rate was determined in [%]. All drug concentrations tested did not hinder the growth of the test strain. Spore formation was inhibited with increasing concentrations of patchouli oil and completely suppressed at 9 ⁇ M / g joint sealant.
  • Example 4 Effect of patchouli oil on the sporulation of Aspergillus niaer on a filter surface after two application of active ingredients
  • Filter papers (2 x 2 cm) were disinfected and 2 x 50 ⁇ l of differently concentrated active ingredient solution (in ethanol) were applied at intervals of 1 h.
  • the test specimens were then dried.
  • the test specimens were then placed on wort agar plates and the surface of wort agar plates was contaminated with 100 ⁇ l of a germ suspension (10 3 CFU / ml) from Aspergillus niger (DSM 1988).
  • the plates were incubated at 25 ° C. for 3 days. Spore formation was assessed visually and the sporulation rate was determined in [%]. All drug concentrations used did not hinder the growth of the test strain. Spore formation was inhibited with increasing concentrations and 95% suppressed at 90 ⁇ M.
  • the pre-portioned detergent is dosed with 50 ml.
  • the detergent is dosed with 75 g.
  • Patchouli alcohol can also be incorporated as a component of the perfume. It is then contained in the perfume oil in concentrations of 0.1 - 80% and is added to the wash liquor via the perfume oil contained in the detergent formulation.
  • the mixtures obtained are mixed with water in a ratio of 1:20 (2) or 1:25 (3) or 1: 1 (4) and used to stick commercially available wallpaper to wall surfaces.

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Abstract

L'invention concerne un agent renfermant de l'huile de patchouli, de l'alcool de patchouli et/ou leurs dérivés, ainsi que l'utilisation de cet agent en vue d'empêcher la multiplication asexuée des champignons, et de diminuer l'adhérence des micro-organismes sur des surfaces. L'invention concerne en outre des supports filtrants renfermant ces substances, et les produits désignés ci-après, renfermant de telles substances : adhésifs, matériaux de construction et/ou auxiliaires de construction, en particulier, produits d'étanchéité et adhésifs, textiles, peaux, papier, fourrures ou cuirs, ainsi que détergents, agents de nettoyage, agents de rinçage, agents de traitement des textiles, produits de lavage manuel, agents détergents pour lavage manuel de vaisselle, agents détergents pour lave-vaisselle, matériaux de construction et auxiliaires de construction, agents cosmétiques et/ou pharmaceutiques, produits pour l'hygiène buccale, soins dentaires et soins de prothèses dentaires, et agents d'apprêtage de produits et auxiliaires utilisés en construction, ainsi que d'apprêtage de textiles, peaux, papier, fourrures ou cuirs.
EP04736635.6A 2003-06-17 2004-06-11 Agents destines a lutter contre les micro-organismes, renfermant de l'huile de patchouli, de l'alcool de patchouli et/ou leurs derives Expired - Lifetime EP1633193B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2003127134 DE10327134A1 (de) 2003-06-17 2003-06-17 Adhäsionshemmung von Mikroorganismen
DE10327138A DE10327138A1 (de) 2003-06-17 2003-06-17 Hemmung der asexuellen Vermehrung von Pilzen
PCT/EP2004/006291 WO2004110153A1 (fr) 2003-06-17 2004-06-11 Agents destines a lutter contre les micro-organismes, renfermant de l'huile de patchouli, de l'alcool de patchouli et/ou leurs derives

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EP1633193A1 true EP1633193A1 (fr) 2006-03-15
EP1633193B1 EP1633193B1 (fr) 2016-05-04

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MX (1) MXPA05013694A (fr)
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DE10327137A1 (de) * 2003-06-17 2005-01-05 Henkel Kgaa Hemmung der asexuellen Vermehrung von Pilzen
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RU2006100650A (ru) 2006-06-10
WO2004110153A1 (fr) 2004-12-23
EP1633193B1 (fr) 2016-05-04
ES2583982T3 (es) 2016-09-23
US20060134239A1 (en) 2006-06-22
KR20060022280A (ko) 2006-03-09

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