EP1201296A1 - Dispositif pour introduire un gaz dans un liquide - Google Patents

Dispositif pour introduire un gaz dans un liquide Download PDF

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Publication number
EP1201296A1
EP1201296A1 EP01811037A EP01811037A EP1201296A1 EP 1201296 A1 EP1201296 A1 EP 1201296A1 EP 01811037 A EP01811037 A EP 01811037A EP 01811037 A EP01811037 A EP 01811037A EP 1201296 A1 EP1201296 A1 EP 1201296A1
Authority
EP
European Patent Office
Prior art keywords
gas
distributor
treatment chamber
treatment room
nozzle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01811037A
Other languages
German (de)
English (en)
Inventor
Roland Hänggi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1201296A1 publication Critical patent/EP1201296A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
    • B01F23/233—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
    • B01F23/233—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements
    • B01F23/2331—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the introduction of the gas along the axis of the stirrer or along the stirrer elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
    • B01F23/233—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements
    • B01F23/2331—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the introduction of the gas along the axis of the stirrer or along the stirrer elements
    • B01F23/23311—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the introduction of the gas along the axis of the stirrer or along the stirrer elements through a hollow stirrer axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
    • B01F23/233—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements
    • B01F23/2331—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the introduction of the gas along the axis of the stirrer or along the stirrer elements
    • B01F23/23314—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the introduction of the gas along the axis of the stirrer or along the stirrer elements through a hollow stirrer element
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
    • B01F23/233—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements
    • B01F23/2334—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements provided with stationary guiding means surrounding at least partially the stirrer
    • B01F23/23341—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements provided with stationary guiding means surrounding at least partially the stirrer with tubes surrounding the stirrer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
    • B01F23/233—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements
    • B01F23/2336—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the location of the place of introduction of the gas relative to the stirrer
    • B01F23/23362—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the location of the place of introduction of the gas relative to the stirrer the gas being introduced under the stirrer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/20—Mixing gases with liquids
    • B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
    • B01F23/2366—Parts; Accessories
    • B01F23/2368—Mixing receptacles, e.g. tanks, vessels or reactors, being completely closed, e.g. hermetically closed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/07—Stirrers characterised by their mounting on the shaft
    • B01F27/072—Stirrers characterised by their mounting on the shaft characterised by the disposition of the stirrers with respect to the rotating axis
    • B01F27/0721—Stirrers characterised by their mounting on the shaft characterised by the disposition of the stirrers with respect to the rotating axis parallel with respect to the rotating axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/112—Stirrers characterised by the configuration of the stirrers with arms, paddles, vanes or blades
    • B01F27/1121—Stirrers characterised by the configuration of the stirrers with arms, paddles, vanes or blades pin-shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/113—Propeller-shaped stirrers for producing an axial flow, e.g. shaped like a ship or aircraft propeller
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/19—Stirrers with two or more mixing elements mounted in sequence on the same axis
    • B01F27/192—Stirrers with two or more mixing elements mounted in sequence on the same axis with dissimilar elements

Definitions

  • the invention relates to a device for gassing, in particular fine-bubble fumigation, of liquid media, such as reaction solutions, Cell cultures and the like.
  • the device has a treatment room and gas supply to a To lead gas up into the treatment room and one gassing liquid or solution contained in it.
  • the Treatment of the liquid medium can be carried out batchwise, continuously or quasi-continuously, the flow rate of the gas passed through the swirl chamber during the treatment process should be stopped in such a way that the liquid medium to be treated during the intended Swirling time is optimally interspersed with the gas.
  • Known devices for gassing liquid media have a wall surrounding the treatment room a window, one at the lower end of the treatment room Gas distributor with at least two by one vertical Axis rotatable divider arms, and at least one vent valve, that has at least one filter.
  • the gas is through a vertical hollow shaft is introduced into the device and with the divider arms rotatable about this shaft, which with are each provided with at least one gas outlet opening into which liquid to be treated introduced.
  • agitators do not have the Requirements for the homogeneity and formulation stability of the product to be manufactured.
  • This process is below the water surface a ventilation gas, namely pure oxygen or an oxygen-containing one Gas mixture, blown into the waste water and it the wastewater is treated centrally from above the tank introduced agitator set in motion.
  • the latter movement in particular does not serve the effect of Increase gas distributor and the degree of distribution of the gas to increase within the treatment room.
  • the invention is based on the object, disadvantages the known devices for gassing liquid media to fix and propose a device in which due to a high degree of division into a liquid or solution introduced gas the efficiency of the fumigation is improved.
  • the gas bubbles rising in the liquid by means of the splitter arms or the distributor plate in helical Orbits are moved before entering the area of effect of the jet mixer.
  • the latter works Formation of an unfavorable gas concentration gradient within of the treatment room by using the medium and the gas floats down in the vertical direction.
  • the jet mixer has a fast-running one Rotor, for example, vertical in a stator Liquid flow generated, which in turn directly on the bottom of the container is directed.
  • jet mixers are suitable for Example the jet stream mixers from Ystral GmbH, DE-Ballrechte-Dottingen.
  • the gas distributor has several, but at least two, preferably three to four, symmetrically having mutually arranged divider arms, or if the distribution plate at least two, preferably three to eight gas outlet openings arranged symmetrically to each other or has gas nozzles.
  • the splitter arms can be made of steel, plastic or the like Materials exist and are round, tubular or polygonal his. Conveniently, they are tubular and they each have a top in the area of the container wall angled end section, at the free end of which at least a gas outlet opening or gas nozzle is arranged.
  • the drive unit for the drive shaft of the Jet mixer and the drive unit for the distribution plate or the splitter arms as independently manageable units trained so that the latter at the desired Place in the liquid pool arranged and fastened can be.
  • the device according to the invention preferably designed so that they are modular can be composed of several components, whereby the elements, if necessary, additionally with an agitator, a homogenizer, or with an integrated in the wall Heating and / or cooling device can be equipped.
  • the device there are additional sensors in the interior of the container available, which can be arranged at different heights and optionally, the gas entry rate, the internal pressure and the Measure inside temperature so that based on the from the measured values measured by various sensors, the gas entry rate, the speed of rotation of the gas distributor and the Speed of the jet mixer manually and / or automatically according to can be controlled according to a predetermined criterion.
  • the criterion can be fixed for the entire treatment be or in the course of treatment in a particular Way, for example according to a time-dependent program, be changed.
  • the device according to the invention can be used, for example, as Fermenter, i.e. for the cultivation of cell and microbe cultures as well as for the biotechnological production of pharmaceutical Active ingredients are used.
  • the device can but also as a reaction container for the production of polymers and the like can be used, that is, wherever a Reaction gas is required to manufacture a product.
  • the device 1 shown in FIG. 1 has a container 2. This is generally rotationally symmetrical to a vertical central axis 3 and has a wall 4. This has a lower, generally cylindrical Wall part 4a with a bottom, two middle, also cylindrical Wall parts 4b and 4c and a lid 4d. The wall parts 4a, 4b, 4c and the cover 4d are detachable as well as tightly connected and can still possibly composed of further detachably connected parts his.
  • the container 2 contains an approximately arranged at the upper end of the lower wall part 4a, horizontal Gas distribution plate described in more detail below 5. This is part of a whole designated 6 Gas separation device, in addition to which a drive unit 7 with a vertical hollow shaft 8 for turning heard of the gas distribution plate 5.
  • the wall 4 of the container 2 borders an interior 9, hereinafter also called treatment room, gastight against the Surroundings.
  • the wall part 4b also has two sight glasses 10 and 11 through which a person enters the treatment room 9 can look into it, and it has the upper middle Wall part 4c a jacket 12 made of glass.
  • the device 1 also has gas guiding means 13 around Process gas, namely air, from bottom to top in the container 2 and in particular to direct its treatment room 9.
  • the gas guide means 13 have an air inlet 14, for example on that over a not drawn filter, also one not shown conditioning and flow control device and a line 15 integrated in the hollow shaft 8 is connected to the gas distribution plate 5.
  • the gas distribution plate 5 is made of stainless steel, for example Steel and has gas pipe means 5b, which at least a gas outlet opening or gas nozzle 16 with the gas line 15 connect the hollow shaft 8, which in turn in the ground of the wall part 4a is used.
  • the gas distribution plate 5 preferably has at least two, for example four to eight or even more symmetrical mutually arranged gas outlet openings 6. These are for example vertical, open at the bottom and closed at the top as well as releasably attached to the distribution plate 5 Caps 17 made of a gas-permeable or porous, textile, metallic or ceramic material covered.
  • the device 1 also has a jet mixer 18 with a high-speed rotor 19, which is in a stator 20 creates a vertical flow of liquid, which is direct is directed to the bottom of the container.
  • the jet mixer 18 is with a holder on a not shown, detachable on the Ceiling 4d attached flange attached.
  • The is driven Jet mixer 18 through a gear unit placed on the cover 4d 21st
  • the treatment room 9 also contains at least one Good inlet, a good outlet and at least one of the Venting gas outlet, further sensors for Measuring the gas entry rate, the internal pressure and the internal temperature.
  • the device additionally has a not shown Control device on.
  • This has, for example, electrical, electronic and possibly pneumatic and / or hydraulic components, manually operated controls, Switching means for the automatic control of the Fumigation, optical signaling devices, analog and / or digital display devices and registration and / or storage devices.
  • the sensors mentioned are through electrical wires connected to the control device. This is also through electrical lines and possibly through fluid lines, i.e. Compressed air and / or hydraulic fluid lines with the controllable motors and / or other drive and / or Actuators of the gas distributor 6, the jet mixer 18 and the gas guide means 13 connected.
  • fluid lines i.e. Compressed air and / or hydraulic fluid lines with the controllable motors and / or other drive and / or Actuators of the gas distributor 6, the jet mixer 18 and the gas guide means 13 connected.
  • the control device is used in particular to Operation depending on different, optionally adjustable or mutually adjustable parameters, such as Pressure of the gas to be introduced, speed of the gas distribution plate 5, speed of the jet mixer 18 and pore size of the Control gas nozzles 16.
  • the device 101 shown in FIG. 2 is in the designed essentially the same as the device 1, thus has an essentially cylindrical container 102 with a vertical central axis 103.
  • the container 102 of the device 101 has a gas separation device arranged in the lower wall part 104a 106 with two rotatable about the axis 103, Gas splitter arms 105 arranged symmetrically to one another. These are connected to the hollow shaft of the gear unit 107 and are formed by uniformly curved pipe bends 108.
  • the pipe bends 108 are hollow stirring bodies, the Interior of the gas line 115 of the hollow shaft with the gas outlet opening 116 connects.
  • the latter is in the present one Case also with one open at the bottom and one closed at the top and detachably attached to the pipe bend 108 Cap 117 made of a gas-permeable or porous, textile, metallic or ceramic material covered.
  • the device according to the invention can be applied to different Species are modified.
  • a stirrer and / or a honing machine be used in the treatment room additionally a stirrer and / or a honing machine.
  • the wall parts of the container 2 and 102 additionally with a heating and / or cooling device, for example a heating and / or Cooling coil, be provided, like that for dryers, Mixer and the like is known.
  • the container wall and / or the heating and / or cooling device can finally also be provided with thermal insulation if the intended operating modes require this.
EP01811037A 2000-10-23 2001-10-23 Dispositif pour introduire un gaz dans un liquide Withdrawn EP1201296A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH20692000 2000-10-23
CH20692000 2000-10-23

Publications (1)

Publication Number Publication Date
EP1201296A1 true EP1201296A1 (fr) 2002-05-02

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EP (1) EP1201296A1 (fr)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7654728B2 (en) 1997-10-24 2010-02-02 Revalesio Corporation System and method for therapeutic application of dissolved oxygen
US7770814B2 (en) 1997-10-24 2010-08-10 Revalesio Corporation System and method for irrigating with aerated water
US7806584B2 (en) 1997-10-24 2010-10-05 Revalesio Corporation Diffuser/emulsifier
US7832920B2 (en) 2006-10-25 2010-11-16 Revalesio Corporation Mixing device for creating an output mixture by mixing a first material and a second material
US7887698B2 (en) 1997-10-24 2011-02-15 Revalesio Corporation Diffuser/emulsifier for aquaculture applications
US8445546B2 (en) 2006-10-25 2013-05-21 Revalesio Corporation Electrokinetically-altered fluids comprising charge-stabilized gas-containing nanostructures
US8784897B2 (en) 2006-10-25 2014-07-22 Revalesio Corporation Methods of therapeutic treatment of eyes
US8784898B2 (en) 2006-10-25 2014-07-22 Revalesio Corporation Methods of wound care and treatment
US8815292B2 (en) 2009-04-27 2014-08-26 Revalesio Corporation Compositions and methods for treating insulin resistance and diabetes mellitus
US8980325B2 (en) 2008-05-01 2015-03-17 Revalesio Corporation Compositions and methods for treating digestive disorders
US9198929B2 (en) 2010-05-07 2015-12-01 Revalesio Corporation Compositions and methods for enhancing physiological performance and recovery time
FR3026654A1 (fr) * 2014-10-03 2016-04-08 Univ Claude Bernard Lyon Dispositif de generation de microbulles
US9402803B2 (en) 2006-10-25 2016-08-02 Revalesio Corporation Methods of wound care and treatment
US9492404B2 (en) 2010-08-12 2016-11-15 Revalesio Corporation Compositions and methods for treatment of taupathy
US9523090B2 (en) 2007-10-25 2016-12-20 Revalesio Corporation Compositions and methods for treating inflammation
US9745567B2 (en) 2008-04-28 2017-08-29 Revalesio Corporation Compositions and methods for treating multiple sclerosis
US10125359B2 (en) 2007-10-25 2018-11-13 Revalesio Corporation Compositions and methods for treating inflammation

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3814396A (en) * 1972-02-16 1974-06-04 Envirotech Corp Aeration apparatus
DE2904101A1 (de) * 1979-02-03 1980-08-14 Ibo W Grimmel Ind Gmbh & Co Kg Verfahren und vorrichtung zur behandlung von abwaessern in belebtschlammbecken
GB2052278A (en) * 1978-11-11 1981-01-28 Streicher M Fluid flow apparatus
DE3034763A1 (de) * 1980-09-15 1982-04-22 Menzel Gmbh & Co Verfahren zum belueften einer fluessigkeit, insbesondere abwasser und vorrichtung zur durchfuehrung des verfahrens
EP0246180A2 (fr) * 1986-05-12 1987-11-19 Mitsubishi Jukogyo Kabushiki Kaisha Appareil pour traiter une solution ou une bouillie
EP0414472A2 (fr) * 1989-08-21 1991-02-27 Exxon Chemical Patents Inc. Procédé pour stripping des systèmes de liquides et système de distribution de gaz pour cela
US5227136A (en) * 1986-02-07 1993-07-13 Envirotech Corporation Bioslurry reactor for treatment of slurries containing minerals, soils and sludges
US5795504A (en) * 1993-03-05 1998-08-18 Berchotteau; Raymond Apparatus for feeding and diffusing air or another gas into a liquid

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3814396A (en) * 1972-02-16 1974-06-04 Envirotech Corp Aeration apparatus
GB2052278A (en) * 1978-11-11 1981-01-28 Streicher M Fluid flow apparatus
DE2904101A1 (de) * 1979-02-03 1980-08-14 Ibo W Grimmel Ind Gmbh & Co Kg Verfahren und vorrichtung zur behandlung von abwaessern in belebtschlammbecken
DE3034763A1 (de) * 1980-09-15 1982-04-22 Menzel Gmbh & Co Verfahren zum belueften einer fluessigkeit, insbesondere abwasser und vorrichtung zur durchfuehrung des verfahrens
US5227136A (en) * 1986-02-07 1993-07-13 Envirotech Corporation Bioslurry reactor for treatment of slurries containing minerals, soils and sludges
EP0246180A2 (fr) * 1986-05-12 1987-11-19 Mitsubishi Jukogyo Kabushiki Kaisha Appareil pour traiter une solution ou une bouillie
EP0414472A2 (fr) * 1989-08-21 1991-02-27 Exxon Chemical Patents Inc. Procédé pour stripping des systèmes de liquides et système de distribution de gaz pour cela
US5795504A (en) * 1993-03-05 1998-08-18 Berchotteau; Raymond Apparatus for feeding and diffusing air or another gas into a liquid

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7654728B2 (en) 1997-10-24 2010-02-02 Revalesio Corporation System and method for therapeutic application of dissolved oxygen
US7770814B2 (en) 1997-10-24 2010-08-10 Revalesio Corporation System and method for irrigating with aerated water
US7806584B2 (en) 1997-10-24 2010-10-05 Revalesio Corporation Diffuser/emulsifier
US9034195B2 (en) 1997-10-24 2015-05-19 Revalesio Corporation Diffuser/emulsifier for aquaculture applications
US7887698B2 (en) 1997-10-24 2011-02-15 Revalesio Corporation Diffuser/emulsifier for aquaculture applications
US8349191B2 (en) 1997-10-24 2013-01-08 Revalesio Corporation Diffuser/emulsifier for aquaculture applications
US8962700B2 (en) 2006-10-25 2015-02-24 Revalesio Corporation Electrokinetically-altered fluids comprising charge-stabilized gas-containing nanostructures
US9512398B2 (en) 2006-10-25 2016-12-06 Revalesio Corporation Ionic aqueous solutions comprising charge-stabilized oxygen-containing nanobubbles
US8470893B2 (en) 2006-10-25 2013-06-25 Revalesio Corporation Electrokinetically-altered fluids comprising charge-stabilized gas-containing nanostructures
US8784897B2 (en) 2006-10-25 2014-07-22 Revalesio Corporation Methods of therapeutic treatment of eyes
US8784898B2 (en) 2006-10-25 2014-07-22 Revalesio Corporation Methods of wound care and treatment
US9511333B2 (en) 2006-10-25 2016-12-06 Revalesio Corporation Ionic aqueous solutions comprising charge-stabilized oxygen-containing nanobubbles
US8445546B2 (en) 2006-10-25 2013-05-21 Revalesio Corporation Electrokinetically-altered fluids comprising charge-stabilized gas-containing nanostructures
US8449172B2 (en) 2006-10-25 2013-05-28 Revalesio Corporation Mixing device for creating an output mixture by mixing a first material and a second material
US9004743B2 (en) 2006-10-25 2015-04-14 Revalesio Corporation Mixing device for creating an output mixture by mixing a first material and a second material
US9402803B2 (en) 2006-10-25 2016-08-02 Revalesio Corporation Methods of wound care and treatment
US7832920B2 (en) 2006-10-25 2010-11-16 Revalesio Corporation Mixing device for creating an output mixture by mixing a first material and a second material
US9523090B2 (en) 2007-10-25 2016-12-20 Revalesio Corporation Compositions and methods for treating inflammation
US10125359B2 (en) 2007-10-25 2018-11-13 Revalesio Corporation Compositions and methods for treating inflammation
US9745567B2 (en) 2008-04-28 2017-08-29 Revalesio Corporation Compositions and methods for treating multiple sclerosis
US8980325B2 (en) 2008-05-01 2015-03-17 Revalesio Corporation Compositions and methods for treating digestive disorders
US9272000B2 (en) 2009-04-27 2016-03-01 Revalesio Corporation Compositions and methods for treating insulin resistance and diabetes mellitus
US9011922B2 (en) 2009-04-27 2015-04-21 Revalesio Corporation Compositions and methods for treating insulin resistance and diabetes mellitus
US8815292B2 (en) 2009-04-27 2014-08-26 Revalesio Corporation Compositions and methods for treating insulin resistance and diabetes mellitus
US9198929B2 (en) 2010-05-07 2015-12-01 Revalesio Corporation Compositions and methods for enhancing physiological performance and recovery time
US9492404B2 (en) 2010-08-12 2016-11-15 Revalesio Corporation Compositions and methods for treatment of taupathy
FR3026654A1 (fr) * 2014-10-03 2016-04-08 Univ Claude Bernard Lyon Dispositif de generation de microbulles

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