EP1197262A3 - Procédé et Dispositif pour la préparation de microsphères - Google Patents
Procédé et Dispositif pour la préparation de microsphères Download PDFInfo
- Publication number
- EP1197262A3 EP1197262A3 EP01301870A EP01301870A EP1197262A3 EP 1197262 A3 EP1197262 A3 EP 1197262A3 EP 01301870 A EP01301870 A EP 01301870A EP 01301870 A EP01301870 A EP 01301870A EP 1197262 A3 EP1197262 A3 EP 1197262A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- plate
- upper body
- lower body
- comprised
- seal ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/41—Emulsifying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/30—Injector mixers
- B01F25/31—Injector mixers in conduits or tubes through which the main component flows
- B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
- B01F25/3142—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/30—Injector mixers
- B01F25/31—Injector mixers in conduits or tubes through which the main component flows
- B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
- B01F25/3142—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction
- B01F25/31425—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction with a plurality of perforations in the axial and circumferential direction covering the whole surface
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Colloid Chemistry (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Glanulating (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Silicon Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000313577 | 2000-10-13 | ||
JP2000313577A JP3511238B2 (ja) | 2000-10-13 | 2000-10-13 | マイクロスフィアの製造方法および製造装置 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1197262A2 EP1197262A2 (fr) | 2002-04-17 |
EP1197262A3 true EP1197262A3 (fr) | 2003-01-02 |
EP1197262B1 EP1197262B1 (fr) | 2006-10-11 |
Family
ID=18792971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01301870A Expired - Lifetime EP1197262B1 (fr) | 2000-10-13 | 2001-03-01 | Procédé et Dispositif pour la préparation de microsphères |
Country Status (4)
Country | Link |
---|---|
US (1) | US6576023B2 (fr) |
EP (1) | EP1197262B1 (fr) |
JP (1) | JP3511238B2 (fr) |
DE (1) | DE60123728T2 (fr) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5127100B2 (ja) * | 2001-04-26 | 2013-01-23 | 東レ・ダウコーニング株式会社 | 硬化性シリコーン組成物の水性エマルジョンの製造方法、その製造装置および硬化シリコーン粒状物の懸濁液の製造方法 |
US20030015425A1 (en) * | 2001-06-20 | 2003-01-23 | Coventor Inc. | Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system |
US20020195343A1 (en) * | 2001-06-20 | 2002-12-26 | Coventor, Inc. | Microfabricated separation device employing a virtual wall for interfacing fluids |
US7718099B2 (en) * | 2002-04-25 | 2010-05-18 | Tosoh Corporation | Fine channel device, fine particle producing method and solvent extraction method |
EP1382384B1 (fr) * | 2002-07-15 | 2011-05-18 | Asahi Glass Company, Limited | Procédé de production de spheres inorganiques |
AU2003266525A1 (en) * | 2002-09-18 | 2004-04-08 | Koyama, Yuu | Process for producing microcapsule |
US20060113239A1 (en) * | 2003-01-31 | 2006-06-01 | Yoshihito Okubo | Device and method of classifying emulsion and method of demulsifying emulsion |
EP1629883B1 (fr) * | 2003-05-13 | 2010-07-28 | Asahi Glass Company Ltd. | Procede pour produire une sphere inorganique |
US7485671B2 (en) * | 2003-05-16 | 2009-02-03 | Velocys, Inc. | Process for forming an emulsion using microchannel process technology |
EP1875959B1 (fr) | 2003-05-16 | 2012-11-28 | Velocys, Inc. | Procédé pour former une émulsion par la technique de traitement en microcanal |
JP4611989B2 (ja) * | 2003-05-16 | 2011-01-12 | ヴェロシス,インク. | マイクロチャネルプロセス技術を用いてエマルジョンを作製するプロセス |
JP5037781B2 (ja) * | 2003-06-11 | 2012-10-03 | 旭硝子株式会社 | 無機質球状体の製造方法及び製造装置 |
KR100932418B1 (ko) * | 2003-06-11 | 2009-12-17 | 아사히 가라스 가부시키가이샤 | 무기질 구상체의 제조 방법 및 제조 장치 |
ATE485886T1 (de) | 2003-06-18 | 2010-11-15 | Asahi Glass Co Ltd | Verfahren und vorrichtung zur herstellung von anorganischen sphären |
JP4578838B2 (ja) * | 2004-03-24 | 2010-11-10 | 株式会社日立プラントテクノロジー | マイクロ流体装置 |
NL1026261C2 (nl) | 2004-05-25 | 2005-11-28 | Nanomi B V | Sproei inrichting met een nozzleplaat voorzien van structuren ter bevordering van self-breakup, een nozzleplaat, alsmede werkwijzen ter vervaardiging en toepassing van een dergelijke nozzleplaat. |
JP4470640B2 (ja) * | 2004-08-12 | 2010-06-02 | 東ソー株式会社 | 微粒子製造方法及びそのための微小流路構造体 |
DE102004040735B4 (de) * | 2004-08-23 | 2006-11-23 | ETH-Zürich, Institut für Lebensmittelwissenschaft, Laboratorium für Lebensmittelverfahrenstechnik | Verfahren zur mechanisch schonenden Erzeugung von fein dispersen Mikro-/Nano-Emulsionen mit enger Tropfengrößenverteilung und Vorrichtung zum Durchführen des Verfahrens |
US7622509B2 (en) * | 2004-10-01 | 2009-11-24 | Velocys, Inc. | Multiphase mixing process using microchannel process technology |
JP3723201B1 (ja) * | 2004-10-18 | 2005-12-07 | 独立行政法人食品総合研究所 | 貫通孔を有する金属製基板を用いたマイクロスフィアの製造方法 |
EP1817098A1 (fr) * | 2004-10-29 | 2007-08-15 | Koninklijke Philips Electronics N.V. | Preparation de dispersions de particules en vue d'une utilisation comme agents de contraste en imagerie ultrasonore |
JP4779173B2 (ja) * | 2005-02-28 | 2011-09-28 | 国立大学法人 岡山大学 | マイクロリアクタ |
JP2007038117A (ja) * | 2005-08-02 | 2007-02-15 | Fujifilm Holdings Corp | 粒子製造方法 |
JP4713397B2 (ja) | 2006-01-18 | 2011-06-29 | 株式会社リコー | 微小流路構造体及び微小液滴生成システム |
GB0611888D0 (en) * | 2006-06-15 | 2006-07-26 | Micropore Technologies Ltd | An apparatus and method for membrane emulsification |
AU2007284454A1 (en) * | 2006-08-17 | 2008-02-21 | Massachusetts Institute Of Technology | Method and apparatus for microfluidic injection |
JP5076742B2 (ja) * | 2006-09-01 | 2012-11-21 | 東ソー株式会社 | 微小流路構造体およびそれを用いた微小粒子製造方法 |
KR101419312B1 (ko) | 2006-09-01 | 2014-07-14 | 도소 가부시키가이샤 | 미소유로 구조 및 그것을 사용한 미소입자 제조 방법 |
US7985058B2 (en) * | 2007-01-12 | 2011-07-26 | Mark Gray | Method and apparatus for making uniformly sized particles |
JP4537421B2 (ja) * | 2007-04-06 | 2010-09-01 | 大日本塗料株式会社 | 単分散粒子の製造方法 |
US20090023189A1 (en) * | 2007-05-18 | 2009-01-22 | Applera Corporation | Apparatus and methods for preparation of subtantially uniform emulsions containing a particle |
NL2002862C2 (en) * | 2009-05-08 | 2010-11-09 | Friesland Brands Bv | Microfluidic apparatus and method for generating a dispersion. |
EP2260917A1 (fr) * | 2009-05-29 | 2010-12-15 | Novoflow GmbH | Système de filtration et procédé pour optimiser la performance de filtration |
CN102686309B (zh) * | 2009-11-12 | 2015-04-08 | 旭硝子株式会社 | 微通道结构体和乳液及固体球状粒子的制造方法 |
CN101862266B (zh) * | 2010-06-01 | 2012-10-10 | 中国人民解放军第三〇九医院 | 单分散性凝胶微球成型装置 |
JP5464105B2 (ja) * | 2010-09-06 | 2014-04-09 | セイコーエプソン株式会社 | ゲル製造装置およびゲル |
WO2014185500A1 (fr) * | 2013-05-16 | 2014-11-20 | 旭硝子株式会社 | Procédé de production de particules hybrides organiques/inorganiques poreuses et dispositif d'émulsification |
FR3043571A1 (fr) | 2015-11-18 | 2017-05-19 | Centre Nat De La Rech Scient - Cnrs - | Procede et dispositif de fabrication d'emulsions |
CN105561897B (zh) * | 2015-12-15 | 2018-02-13 | 哈尔滨理工大学 | 制备环状微凝胶的*** |
KR101833610B1 (ko) | 2016-03-22 | 2018-03-02 | 부산대학교 산학협력단 | 미세 입자 제조 장치 |
US11130120B2 (en) * | 2018-10-01 | 2021-09-28 | Lifeng XIAO | Micro-pipette tip for forming micro-droplets |
CA3144281C (fr) | 2019-07-01 | 2023-08-22 | Oakwood Laboratories, Llc | Systeme et procede de fabrication de microspheres et d'emulsions |
CN111531426A (zh) * | 2020-04-27 | 2020-08-14 | 徐巧芳 | 一种用于机械加工的板材磨边装置 |
KR102407749B1 (ko) * | 2020-04-29 | 2022-06-13 | 경희대학교 산학협력단 | 액적을 생성하는 방법 및 장치 |
KR102419669B1 (ko) * | 2020-04-29 | 2022-07-08 | 경희대학교 산학협력단 | 적어도 하나의 미세유동구조물을 포함하는 미세 유동 장치 및 이에 공급된 시료의 분석방법 |
CN113877499A (zh) * | 2021-10-08 | 2022-01-04 | 南京大学 | 一种均粒树脂生产装置及其使用方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0295433A (ja) * | 1988-09-29 | 1990-04-06 | Miyazaki Pref Gov | エマルションの製造方法 |
DE19908171A1 (de) * | 1998-03-30 | 1999-10-07 | Nat Food Res | Kontinuierliches Herstellungsverfahren für Mikrokugeln und Vorrichtung hierfür |
EP0963787A1 (fr) * | 1996-02-20 | 1999-12-15 | JAPAN as represented by DIRECTOR GENERAL OF NATIONAL FOOD RESEARCH INSTITUTE, MINISTRY OF AGRICULTURE, FORESTRY AND FISHERIES | Procede et dispositif pour produire des emulsions |
GB2339397A (en) * | 1998-07-02 | 2000-01-26 | Agency Ind Science Techn | Cross-flow microchannel apparatus for producing or separating emulsions |
WO2000059625A1 (fr) * | 1999-04-06 | 2000-10-12 | E Ink Corporation | Procedes de production de gouttelettes destines a des afficheurs par electrophorese encapsules |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3747759A (en) | 1971-05-19 | 1973-07-24 | G Olgard | Arrangement for separation of suspended or emulsified material from aliquid |
US4000086A (en) * | 1975-04-28 | 1976-12-28 | Vish Minno-Geoloshki Institute - Nis | Method of and apparatus for emulsification |
US4201691A (en) | 1978-01-16 | 1980-05-06 | Exxon Research & Engineering Co. | Liquid membrane generator |
US4533254A (en) | 1981-04-17 | 1985-08-06 | Biotechnology Development Corporation | Apparatus for forming emulsions |
US4534388A (en) | 1983-06-07 | 1985-08-13 | Pall Corporation | Dispersion system and method |
US5063002A (en) * | 1988-07-27 | 1991-11-05 | Exxon Chemical Patents Inc. | Method for producing an elastomeric crumb using gas to first cut an extruded hot, sticky elastomeric extrudate material, form the crumb, and then convey it away |
WO1993000156A1 (fr) | 1991-06-29 | 1993-01-07 | Miyazaki-Ken | Emulsions monodispersees simples et doubles et procede de production |
EP0546174B1 (fr) | 1991-06-29 | 1997-10-29 | Miyazaki-Ken | Emulsions monodispersees simples et doubles et procede de production |
US5247957A (en) | 1991-10-24 | 1993-09-28 | H. B. Fuller Company | Modular lubrication multiple concentration control apparatus |
JP3144897B2 (ja) | 1992-07-15 | 2001-03-12 | 野村マイクロ・サイエンス株式会社 | 懸濁脂質粒子製造用フィルターユニットおよび懸濁脂質粒子の製造方法 |
US5626751A (en) * | 1992-07-15 | 1997-05-06 | Daiichi Pharmaceutical Co., Ltd. | Filter unit and high-pressure sizing apparatus |
JP3242776B2 (ja) | 1992-12-01 | 2001-12-25 | 宮崎県 | 乳化装置 |
DE4405005A1 (de) | 1994-02-17 | 1995-08-24 | Rossendorf Forschzent | Mikro-Fluiddiode |
DE19511603A1 (de) | 1995-03-30 | 1996-10-02 | Norbert Dr Ing Schwesinger | Vorrichtung zum Mischen kleiner Flüssigkeitsmengen |
US5842787A (en) | 1997-10-09 | 1998-12-01 | Caliper Technologies Corporation | Microfluidic systems incorporating varied channel dimensions |
-
2000
- 2000-10-13 JP JP2000313577A patent/JP3511238B2/ja not_active Expired - Lifetime
-
2001
- 2001-02-22 US US09/791,085 patent/US6576023B2/en not_active Expired - Lifetime
- 2001-03-01 DE DE60123728T patent/DE60123728T2/de not_active Expired - Lifetime
- 2001-03-01 EP EP01301870A patent/EP1197262B1/fr not_active Expired - Lifetime
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0295433A (ja) * | 1988-09-29 | 1990-04-06 | Miyazaki Pref Gov | エマルションの製造方法 |
EP0963787A1 (fr) * | 1996-02-20 | 1999-12-15 | JAPAN as represented by DIRECTOR GENERAL OF NATIONAL FOOD RESEARCH INSTITUTE, MINISTRY OF AGRICULTURE, FORESTRY AND FISHERIES | Procede et dispositif pour produire des emulsions |
DE19908171A1 (de) * | 1998-03-30 | 1999-10-07 | Nat Food Res | Kontinuierliches Herstellungsverfahren für Mikrokugeln und Vorrichtung hierfür |
GB2339397A (en) * | 1998-07-02 | 2000-01-26 | Agency Ind Science Techn | Cross-flow microchannel apparatus for producing or separating emulsions |
WO2000059625A1 (fr) * | 1999-04-06 | 2000-10-12 | E Ink Corporation | Procedes de production de gouttelettes destines a des afficheurs par electrophorese encapsules |
Non-Patent Citations (1)
Title |
---|
DATABASE WPI Section Ch Week 199020, Derwent World Patents Index; Class A35, AN 1990-151461, XP002218884 * |
Also Published As
Publication number | Publication date |
---|---|
EP1197262B1 (fr) | 2006-10-11 |
JP3511238B2 (ja) | 2004-03-29 |
US6576023B2 (en) | 2003-06-10 |
US20020043731A1 (en) | 2002-04-18 |
EP1197262A2 (fr) | 2002-04-17 |
JP2002119841A (ja) | 2002-04-23 |
DE60123728D1 (de) | 2006-11-23 |
DE60123728T2 (de) | 2007-10-11 |
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