EP1141295A4 - Human chemokine beta-10 mutant polypeptides - Google Patents

Human chemokine beta-10 mutant polypeptides

Info

Publication number
EP1141295A4
EP1141295A4 EP00903142A EP00903142A EP1141295A4 EP 1141295 A4 EP1141295 A4 EP 1141295A4 EP 00903142 A EP00903142 A EP 00903142A EP 00903142 A EP00903142 A EP 00903142A EP 1141295 A4 EP1141295 A4 EP 1141295A4
Authority
EP
European Patent Office
Prior art keywords
mutant polypeptides
human chemokine
chemokine beta
beta
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00903142A
Other languages
German (de)
French (fr)
Other versions
EP1141295A1 (en
Inventor
Henrik S Olsen
Haodong Li
Mark D Adams
Solange H L Gentz
Ralph Alderson
Yuling Li
David Parmelee
John R White
Edward R Appelbaum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
SmithKline Beecham Corp
Original Assignee
Human Genome Sciences Inc
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc, SmithKline Beecham Corp filed Critical Human Genome Sciences Inc
Publication of EP1141295A1 publication Critical patent/EP1141295A1/en
Publication of EP1141295A4 publication Critical patent/EP1141295A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/523Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP00903142A 1999-01-08 2000-01-07 Human chemokine beta-10 mutant polypeptides Withdrawn EP1141295A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11543999P 1999-01-08 1999-01-08
US115439P 1999-01-08
PCT/US2000/000296 WO2000040726A1 (en) 1999-01-08 2000-01-07 Human chemokine beta-10 mutant polypeptides

Publications (2)

Publication Number Publication Date
EP1141295A1 EP1141295A1 (en) 2001-10-10
EP1141295A4 true EP1141295A4 (en) 2002-09-18

Family

ID=22361410

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00903142A Withdrawn EP1141295A4 (en) 1999-01-08 2000-01-07 Human chemokine beta-10 mutant polypeptides

Country Status (4)

Country Link
EP (1) EP1141295A4 (en)
AU (1) AU2493000A (en)
CA (1) CA2359853A1 (en)
WO (1) WO2000040726A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6989247B2 (en) * 2000-11-28 2006-01-24 Celltech R & D, Inc. Compositions and methods for diagnosing or treating psoriasis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997031098A1 (en) * 1996-02-23 1997-08-28 Human Genome Sciences, Inc. Human chemokine polypeptides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9308060D0 (en) * 1993-04-19 1993-06-02 Cancer Res Campaign Tech Stem cell inhibitor
US5981230A (en) * 1994-08-23 1999-11-09 Human Genome Sciences, Inc. Polynucleotide encoding chemokine β-4
WO1997015594A1 (en) * 1995-10-24 1997-05-01 Smithkline Beecham Corporation Novel chemokine for mobilizing stem cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997031098A1 (en) * 1996-02-23 1997-08-28 Human Genome Sciences, Inc. Human chemokine polypeptides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GARCIA-ZEPEDA E A ET AL: "HUMAN MONOCYTE CHEMOATTRACTANT PROTEIN (MCP)-4 IS A NOVEL CC CHEMOKINE WITH ACTIVITIES ON MONOCYTES, EOSINOPHILS, AND BASOPHILS INDUCED IN ALLERGIC AND NONALLERGIC INFLAMMATION THAT SIGNALS THROUGH THE CC CHEMOKINE RECEPTORS (CCR)-2 AND -3", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, vol. 157, no. 12, 15 December 1996 (1996-12-15), pages 5613 - 5626, XP002034960, ISSN: 0022-1767 *
See also references of WO0040726A1 *
UGUCCIONI M ET AL: "MONOCYTE CHEMOTACTIC PROTEIN 4 (MCP-4), A NOVEL STRUCTURAL AND FUNCTIONAL ANALOGUE OF MCP-3 AND EOTAXIN", JOURNAL OF EXPERIMENTAL MEDICINE, TOKYO, JP, vol. 183, no. 5, 1 May 1996 (1996-05-01), pages 2379 - 2384, XP002035227, ISSN: 0022-1007 *

Also Published As

Publication number Publication date
WO2000040726A1 (en) 2000-07-13
EP1141295A1 (en) 2001-10-10
AU2493000A (en) 2000-07-24
CA2359853A1 (en) 2000-07-13

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