EP1045029A3 - Procédé de préparation des acides 4-hydroxy-2-ketoglutarique optiquement actifs - Google Patents

Procédé de préparation des acides 4-hydroxy-2-ketoglutarique optiquement actifs Download PDF

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Publication number
EP1045029A3
EP1045029A3 EP00117178A EP00117178A EP1045029A3 EP 1045029 A3 EP1045029 A3 EP 1045029A3 EP 00117178 A EP00117178 A EP 00117178A EP 00117178 A EP00117178 A EP 00117178A EP 1045029 A3 EP1045029 A3 EP 1045029A3
Authority
EP
European Patent Office
Prior art keywords
acid
hydroxy
optically active
ketoglutaric
producing optically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00117178A
Other languages
German (de)
English (en)
Other versions
EP1045029A2 (fr
Inventor
Ryoichi Katsumata
Shinichi Hashimoto
Keiko Ochiai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of EP1045029A2 publication Critical patent/EP1045029A2/fr
Publication of EP1045029A3 publication Critical patent/EP1045029A3/fr
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/50—Polycarboxylic acids having keto groups, e.g. 2-ketoglutaric acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/41—Rhizobium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas
    • Y10S435/877—Pseudomonas putida

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP00117178A 1994-03-01 1995-03-01 Procédé de préparation des acides 4-hydroxy-2-ketoglutarique optiquement actifs Withdrawn EP1045029A3 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP3133594 1994-03-01
JP3133594 1994-03-01
JP8306594 1994-04-21
JP08306594A JP3698742B2 (ja) 1994-03-01 1994-04-21 光学活性４−ヒドロキシ−２−ケトグルタル酸の製造法
EP95301322A EP0670371B1 (fr) 1994-03-01 1995-03-01 Procédé de préparation des acides 4-hydroxy-2-ketoglutarique optiquement actifs

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP95301322A Division EP0670371B1 (fr) 1994-03-01 1995-03-01 Procédé de préparation des acides 4-hydroxy-2-ketoglutarique optiquement actifs

Publications (2)

Publication Number Publication Date
EP1045029A2 EP1045029A2 (fr) 2000-10-18
EP1045029A3 true EP1045029A3 (fr) 2000-11-22

Family

ID=26369781

Family Applications (2)

Application Number Title Priority Date Filing Date
EP95301322A Expired - Lifetime EP0670371B1 (fr) 1994-03-01 1995-03-01 Procédé de préparation des acides 4-hydroxy-2-ketoglutarique optiquement actifs
EP00117178A Withdrawn EP1045029A3 (fr) 1994-03-01 1995-03-01 Procédé de préparation des acides 4-hydroxy-2-ketoglutarique optiquement actifs

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP95301322A Expired - Lifetime EP0670371B1 (fr) 1994-03-01 1995-03-01 Procédé de préparation des acides 4-hydroxy-2-ketoglutarique optiquement actifs

Country Status (5)

Country Link
US (1) US5607848A (fr)
EP (2) EP0670371B1 (fr)
JP (1) JP3698742B2 (fr)
CA (1) CA2143545C (fr)
DE (1) DE69528008T2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8202711B2 (en) 2001-12-27 2012-06-19 Ajinomoto Co., Inc. Process for producing glutamate derivatives
US8273556B2 (en) 2002-08-26 2012-09-25 Ajinomoto Co., Inc. Aldolase and production process of substituted α-keto acids

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2234412C (fr) 1997-06-09 2008-09-02 Kyowa Hakko Kogyo Co., Ltd. Methode de production d'un compose optiquement actif
US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
CN100516043C (zh) 2002-04-23 2009-07-22 嘉吉有限公司 多肽和生物合成途径
US7572607B2 (en) 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
WO2005014839A2 (fr) 2003-08-01 2005-02-17 Cargill, Incorporated Compositions d'edulcorants de table a base de monatine et procedes de fabrication associes
CN1890377B (zh) 2003-10-21 2013-06-05 嘉吉有限公司 生产莫纳甜和莫纳甜前体
US8158389B2 (en) 2005-04-20 2012-04-17 Cargill, Incorporated Products and methods for in vivo secretion of monatin
WO2006113897A2 (fr) 2005-04-20 2006-10-26 Cargill, Incorporated Produits et procedes de secretion de monatine in vivo
US8076108B2 (en) 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US7582455B2 (en) 2005-04-26 2009-09-01 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
JP5441417B2 (ja) 2006-03-07 2014-03-12 カーギル・インコーポレイテッド アルドース、それをコードする核酸、ならびにそれを生成および使用する方法
WO2007140195A2 (fr) 2006-05-24 2007-12-06 Cargill, Incorporated Procédés et systèmes permettant d'augmenter la production de réactions d'équilibre
US8003361B2 (en) 2007-10-01 2011-08-23 Cargill Incorporated Production of monatin enantiomers
US8367847B2 (en) 2007-10-01 2013-02-05 Cargill, Incorporated Production of monatin enantiomers
US8076107B2 (en) * 2007-10-01 2011-12-13 Cargill, Incorporated Production of monatin stereoisomers

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0313850A1 (fr) * 1987-10-01 1989-05-03 BASF Aktiengesellschaft Procédé de préparation de l'acide pyruvique
EP0378000A2 (fr) * 1989-01-06 1990-07-18 Agricultural Genetics Company Limited Enrobage de semences
EP0389620A1 (fr) * 1987-08-21 1990-10-03 Toray Industries, Inc. Procede de preparation de l'acide pyruvique par fermentation
EP0555475A1 (fr) * 1991-08-26 1993-08-18 Kyowa Hakko Kogyo Co., Ltd. Procede pour la production de 4-hydroxy-l-proline

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU636262A1 (ru) * 1977-03-15 1978-12-05 Институт Микробиологии Имени Августа Кирхенштейна Ан Латвийской Сср Штамм продуцент -кетоглутаровой и пировиноградной кислот
JP3078296B2 (ja) * 1990-03-19 2000-08-21 協和醗酵工業株式会社 ４―ヒドロキシ―ｌ―プロリンの製造法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0389620A1 (fr) * 1987-08-21 1990-10-03 Toray Industries, Inc. Procede de preparation de l'acide pyruvique par fermentation
EP0313850A1 (fr) * 1987-10-01 1989-05-03 BASF Aktiengesellschaft Procédé de préparation de l'acide pyruvique
EP0378000A2 (fr) * 1989-01-06 1990-07-18 Agricultural Genetics Company Limited Enrobage de semences
EP0555475A1 (fr) * 1991-08-26 1993-08-18 Kyowa Hakko Kogyo Co., Ltd. Procede pour la production de 4-hydroxy-l-proline

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FLOYD, N.C., ET AL.: "A simple strategy for obtaining both enantiomers from an aldolase reaction: Preparation of L- and D-4-hydroxy-2- ketoglutarate.", JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 1., no. 9, 1992, LETCHWORTH GB, pages 1085 - 1086, XP002048446 *
MARUYAMA K.: "Purification and properties of 4-hydroxy-4-methyl-2-oxoglutarate aldolase from Pseudomonas ochraceae grown on phtalate.", JOURNAL OF BIOCHEMISTRY, vol. 108, no. 2, 1990, TOKYO,JP, pages 327 - 333, XP002048447 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8202711B2 (en) 2001-12-27 2012-06-19 Ajinomoto Co., Inc. Process for producing glutamate derivatives
US8535920B2 (en) 2001-12-27 2013-09-17 Ajinomoto Co., Inc. Process for producing glutamate derivatives
US8563278B2 (en) 2001-12-27 2013-10-22 Ajinomoto Co., Inc. Process of producing glutamate derivatives
US8273556B2 (en) 2002-08-26 2012-09-25 Ajinomoto Co., Inc. Aldolase and production process of substituted α-keto acids
US8697416B2 (en) 2002-08-26 2014-04-15 Ajinomoto Co., Inc. Recombinant polynucleotide, host cells containing the same and a process for producing a protein having aldolase activity

Also Published As

Publication number Publication date
EP0670371B1 (fr) 2002-09-04
DE69528008T2 (de) 2003-04-30
EP0670371A2 (fr) 1995-09-06
CA2143545C (fr) 2009-07-14
DE69528008D1 (de) 2002-10-10
JPH07289284A (ja) 1995-11-07
US5607848A (en) 1997-03-04
CA2143545A1 (fr) 1995-09-02
JP3698742B2 (ja) 2005-09-21
EP0670371A3 (fr) 1998-02-18
EP1045029A2 (fr) 2000-10-18

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