EP1023316A4 - METHODS AND COMPOSITIONS FOR LIPIDIZING HYDROPHILIC MOLECULES - Google Patents
METHODS AND COMPOSITIONS FOR LIPIDIZING HYDROPHILIC MOLECULESInfo
- Publication number
- EP1023316A4 EP1023316A4 EP97944483A EP97944483A EP1023316A4 EP 1023316 A4 EP1023316 A4 EP 1023316A4 EP 97944483 A EP97944483 A EP 97944483A EP 97944483 A EP97944483 A EP 97944483A EP 1023316 A4 EP1023316 A4 EP 1023316A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- lipidization
- compositions
- methods
- hydrophilic molecules
- hydrophilic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72130696A | 1996-09-26 | 1996-09-26 | |
US77177P | 1996-09-26 | ||
US4949997P | 1997-06-13 | 1997-06-13 | |
US49499P | 1997-06-13 | ||
PCT/US1997/017282 WO1998013007A2 (en) | 1996-09-26 | 1997-09-26 | Methods and compositions for lipidization of hydrophilic molecules |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1023316A2 EP1023316A2 (en) | 2000-08-02 |
EP1023316A4 true EP1023316A4 (en) | 2004-06-09 |
Family
ID=26727231
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97944483A Ceased EP1023316A4 (en) | 1996-09-26 | 1997-09-26 | METHODS AND COMPOSITIONS FOR LIPIDIZING HYDROPHILIC MOLECULES |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1023316A4 (pt) |
JP (1) | JP2002515883A (pt) |
KR (1) | KR100691315B1 (pt) |
CN (1) | CN1127477C (pt) |
AU (1) | AU737865B2 (pt) |
BR (1) | BR9712128A (pt) |
CA (1) | CA2267179A1 (pt) |
IL (1) | IL129177A0 (pt) |
NO (1) | NO991465L (pt) |
WO (1) | WO1998013007A2 (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6169078B1 (en) * | 1998-05-12 | 2001-01-02 | University Of Florida | Materials and methods for the intracellular delivery of substances |
TWI242000B (en) * | 1998-12-10 | 2005-10-21 | Univ Southern California | Reversible aqueous pH sensitive lipidizing reagents, compositions and methods of use |
GB0103877D0 (en) * | 2001-02-16 | 2001-04-04 | King S College London | Novel Drug Delivery system |
US20050054612A1 (en) * | 2003-09-08 | 2005-03-10 | Monahan Sean D. | Delivery by labile hydrophobic modification of drugs |
CA2551131A1 (en) * | 2003-12-31 | 2005-07-21 | Centocor, Inc. | Novel recombinant proteins with n-terminal free thiol |
WO2008057298A2 (en) * | 2006-10-27 | 2008-05-15 | Wei-Chiang Shen | Lipidized interferon and uses thereof |
WO2008109119A2 (en) * | 2007-03-05 | 2008-09-12 | The Board Of Trustees Of The Leland Stanford Junior University | Wnt compositions and methods of use thereof |
CA2716255C (en) * | 2008-02-21 | 2016-11-29 | Dermacare Neuroscience Institute | Cosmetic and dermatological formulations of mntf peptides |
CN105283441B (zh) * | 2013-02-28 | 2018-10-23 | 塔夫茨大学 | 用于递送药剂的二硫化合物 |
US20160082126A1 (en) * | 2013-05-13 | 2016-03-24 | Tufts University | Nanocomplexes for delivery of saporin |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996022773A1 (en) * | 1995-01-25 | 1996-08-01 | University Of Southern California | Methods and compositions for lipidization of hydrophilic molecules |
WO1997049425A1 (en) * | 1996-06-25 | 1997-12-31 | Stichting Instituut Voor Dierhouderij En Diergezondheid | Vaccine comprising antigens bound to carriers through labile bonds |
-
1997
- 1997-09-26 EP EP97944483A patent/EP1023316A4/en not_active Ceased
- 1997-09-26 AU AU45967/97A patent/AU737865B2/en not_active Ceased
- 1997-09-26 JP JP51593398A patent/JP2002515883A/ja not_active Ceased
- 1997-09-26 KR KR1019997002543A patent/KR100691315B1/ko not_active IP Right Cessation
- 1997-09-26 CA CA002267179A patent/CA2267179A1/en not_active Abandoned
- 1997-09-26 BR BR9712128-2A patent/BR9712128A/pt not_active Application Discontinuation
- 1997-09-26 IL IL12917797A patent/IL129177A0/xx not_active IP Right Cessation
- 1997-09-26 CN CN97199191A patent/CN1127477C/zh not_active Expired - Fee Related
- 1997-09-26 WO PCT/US1997/017282 patent/WO1998013007A2/en active IP Right Grant
-
1999
- 1999-03-25 NO NO991465A patent/NO991465L/no not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996022773A1 (en) * | 1995-01-25 | 1996-08-01 | University Of Southern California | Methods and compositions for lipidization of hydrophilic molecules |
WO1997049425A1 (en) * | 1996-06-25 | 1997-12-31 | Stichting Instituut Voor Dierhouderij En Diergezondheid | Vaccine comprising antigens bound to carriers through labile bonds |
Non-Patent Citations (1)
Title |
---|
KIWADA H ET AL: "Application of synthetic liposomes based on acyl amino acids or acyl peptides as drug carriers. I. Their preparation and transport of glutathione into the liver.", CHEMICAL & PHARMACEUTICAL BULLETIN. JUL 1987, vol. 35, no. 7, July 1987 (1987-07-01), pages 2935 - 2942, XP002276804, ISSN: 0009-2363 * |
Also Published As
Publication number | Publication date |
---|---|
CN1127477C (zh) | 2003-11-12 |
WO1998013007A2 (en) | 1998-04-02 |
AU737865B2 (en) | 2001-09-06 |
CN1235594A (zh) | 1999-11-17 |
WO1998013007A8 (en) | 1999-05-20 |
KR100691315B1 (ko) | 2007-03-12 |
BR9712128A (pt) | 2000-12-12 |
KR20000048608A (ko) | 2000-07-25 |
NO991465L (no) | 1999-05-10 |
EP1023316A2 (en) | 2000-08-02 |
AU4596797A (en) | 1998-04-17 |
NO991465D0 (no) | 1999-03-25 |
CA2267179A1 (en) | 1998-04-02 |
IL129177A0 (en) | 2000-02-17 |
JP2002515883A (ja) | 2002-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19990422 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
R17D | Deferred search report published (corrected) |
Effective date: 19980402 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20040426 |
|
17Q | First examination report despatched |
Effective date: 20050517 |
|
17Q | First examination report despatched |
Effective date: 20050517 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
18R | Application refused |
Effective date: 20071129 |