IL129177A0 - Methods and compositions for lipidization of hydrophilic molecules - Google Patents

Methods and compositions for lipidization of hydrophilic molecules

Info

Publication number
IL129177A0
IL129177A0 IL12917797A IL12917797A IL129177A0 IL 129177 A0 IL129177 A0 IL 129177A0 IL 12917797 A IL12917797 A IL 12917797A IL 12917797 A IL12917797 A IL 12917797A IL 129177 A0 IL129177 A0 IL 129177A0
Authority
IL
Israel
Prior art keywords
lipidization
compositions
methods
hydrophilic molecules
hydrophilic
Prior art date
Application number
IL12917797A
Other languages
English (en)
Original Assignee
Univ Southern California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Southern California filed Critical Univ Southern California
Publication of IL129177A0 publication Critical patent/IL129177A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL12917797A 1996-09-26 1997-09-26 Methods and compositions for lipidization of hydrophilic molecules IL129177A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72130696A 1996-09-26 1996-09-26
US4949997P 1997-06-13 1997-06-13
PCT/US1997/017282 WO1998013007A2 (en) 1996-09-26 1997-09-26 Methods and compositions for lipidization of hydrophilic molecules

Publications (1)

Publication Number Publication Date
IL129177A0 true IL129177A0 (en) 2000-02-17

Family

ID=26727231

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12917797A IL129177A0 (en) 1996-09-26 1997-09-26 Methods and compositions for lipidization of hydrophilic molecules

Country Status (10)

Country Link
EP (1) EP1023316A4 (xx)
JP (1) JP2002515883A (xx)
KR (1) KR100691315B1 (xx)
CN (1) CN1127477C (xx)
AU (1) AU737865B2 (xx)
BR (1) BR9712128A (xx)
CA (1) CA2267179A1 (xx)
IL (1) IL129177A0 (xx)
NO (1) NO991465L (xx)
WO (1) WO1998013007A2 (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6169078B1 (en) * 1998-05-12 2001-01-02 University Of Florida Materials and methods for the intracellular delivery of substances
TWI242000B (en) * 1998-12-10 2005-10-21 Univ Southern California Reversible aqueous pH sensitive lipidizing reagents, compositions and methods of use
GB0103877D0 (en) * 2001-02-16 2001-04-04 King S College London Novel Drug Delivery system
US20050054612A1 (en) * 2003-09-08 2005-03-10 Monahan Sean D. Delivery by labile hydrophobic modification of drugs
CA2551131A1 (en) * 2003-12-31 2005-07-21 Centocor, Inc. Novel recombinant proteins with n-terminal free thiol
WO2008057298A2 (en) * 2006-10-27 2008-05-15 Wei-Chiang Shen Lipidized interferon and uses thereof
WO2008109119A2 (en) * 2007-03-05 2008-09-12 The Board Of Trustees Of The Leland Stanford Junior University Wnt compositions and methods of use thereof
CA2716255C (en) * 2008-02-21 2016-11-29 Dermacare Neuroscience Institute Cosmetic and dermatological formulations of mntf peptides
CN105283441B (zh) * 2013-02-28 2018-10-23 塔夫茨大学 用于递送药剂的二硫化合物
US20160082126A1 (en) * 2013-05-13 2016-03-24 Tufts University Nanocomplexes for delivery of saporin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5907030A (en) * 1995-01-25 1999-05-25 University Of Southern California Method and compositions for lipidization of hydrophilic molecules
BR9709993A (pt) * 1996-06-25 1999-08-10 Stichting Inst Dierhouderij Vacina preparação de vacina composição processo para produção de uma preparação imugênica e preparação imugênica

Also Published As

Publication number Publication date
CN1127477C (zh) 2003-11-12
WO1998013007A2 (en) 1998-04-02
AU737865B2 (en) 2001-09-06
CN1235594A (zh) 1999-11-17
EP1023316A4 (en) 2004-06-09
WO1998013007A8 (en) 1999-05-20
KR100691315B1 (ko) 2007-03-12
BR9712128A (pt) 2000-12-12
KR20000048608A (ko) 2000-07-25
NO991465L (no) 1999-05-10
EP1023316A2 (en) 2000-08-02
AU4596797A (en) 1998-04-17
NO991465D0 (no) 1999-03-25
CA2267179A1 (en) 1998-04-02
JP2002515883A (ja) 2002-05-28

Similar Documents

Publication Publication Date Title
HUP9901321A3 (en) Methods and compositions for determining the sequence of nucleic acid molecules
AU2113295A (en) Novel compositions and methods for water treatment
PL327658A1 (en) Disinfecting compositions and methods of disinfecting surfaces
AU3850395A (en) Hemorrhoidal compositions and method of use
AU2747497A (en) Compositions and methods for antisense inhibition of protein translation
PL330311A1 (en) Settling tank air purification purposes and method of making same
HUP9700602A3 (en) New inhibitors of bone-resorption and vitronectine-receptor-antagonists
CY2178B1 (en) Naphthyl compounds intermediates compositions and methods
AU5439996A (en) Compositions and methods for treating pain
EP0949407A4 (en) EXHAUST APPARATUS FOR VEHICLES
AU9214398A (en) Compositions and methods for treating water
AU1532297A (en) Starch-emulsifier composition and methods of making
EP0960191A4 (en) COMPOSITIONS AND METHODS FOR THE USE OF DEFENSIN
AU4108097A (en) Microballoons-containing composition of polydimethylsiloxane
PL327945A1 (en) Disinfecting compositions and methods of disinfecting surfaces
HUP9901883A3 (en) Disinfecting composition and process for disinfecting surfaces
AU5605398A (en) Novel methods and compositions for treatment of autoimmune diseases
AU4248597A (en) Methods and compositions for treating preterm labor
AU2821295A (en) Compositions and methods for the treatment of tumors
AU2387097A (en) Substituted benzylamines and their use for the treatment of depression
AU2807297A (en) Methods of treating wastewater
IL129177A0 (en) Methods and compositions for lipidization of hydrophilic molecules
AU1714697A (en) Method and composition for the treatment of osteoarthritis
ZA977619B (en) Naphthyl compounds intermediates compositions and methods of use
AU3127795A (en) Composition and treatment for baldness

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees