IL129177A0 - Methods and compositions for lipidization of hydrophilic molecules - Google Patents
Methods and compositions for lipidization of hydrophilic moleculesInfo
- Publication number
- IL129177A0 IL129177A0 IL12917797A IL12917797A IL129177A0 IL 129177 A0 IL129177 A0 IL 129177A0 IL 12917797 A IL12917797 A IL 12917797A IL 12917797 A IL12917797 A IL 12917797A IL 129177 A0 IL129177 A0 IL 129177A0
- Authority
- IL
- Israel
- Prior art keywords
- lipidization
- compositions
- methods
- hydrophilic molecules
- hydrophilic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72130696A | 1996-09-26 | 1996-09-26 | |
US4949997P | 1997-06-13 | 1997-06-13 | |
PCT/US1997/017282 WO1998013007A2 (en) | 1996-09-26 | 1997-09-26 | Methods and compositions for lipidization of hydrophilic molecules |
Publications (1)
Publication Number | Publication Date |
---|---|
IL129177A0 true IL129177A0 (en) | 2000-02-17 |
Family
ID=26727231
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12917797A IL129177A0 (en) | 1996-09-26 | 1997-09-26 | Methods and compositions for lipidization of hydrophilic molecules |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1023316A4 (xx) |
JP (1) | JP2002515883A (xx) |
KR (1) | KR100691315B1 (xx) |
CN (1) | CN1127477C (xx) |
AU (1) | AU737865B2 (xx) |
BR (1) | BR9712128A (xx) |
CA (1) | CA2267179A1 (xx) |
IL (1) | IL129177A0 (xx) |
NO (1) | NO991465L (xx) |
WO (1) | WO1998013007A2 (xx) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6169078B1 (en) * | 1998-05-12 | 2001-01-02 | University Of Florida | Materials and methods for the intracellular delivery of substances |
TWI242000B (en) * | 1998-12-10 | 2005-10-21 | Univ Southern California | Reversible aqueous pH sensitive lipidizing reagents, compositions and methods of use |
GB0103877D0 (en) * | 2001-02-16 | 2001-04-04 | King S College London | Novel Drug Delivery system |
US20050054612A1 (en) * | 2003-09-08 | 2005-03-10 | Monahan Sean D. | Delivery by labile hydrophobic modification of drugs |
CA2551131A1 (en) * | 2003-12-31 | 2005-07-21 | Centocor, Inc. | Novel recombinant proteins with n-terminal free thiol |
WO2008057298A2 (en) * | 2006-10-27 | 2008-05-15 | Wei-Chiang Shen | Lipidized interferon and uses thereof |
WO2008109119A2 (en) * | 2007-03-05 | 2008-09-12 | The Board Of Trustees Of The Leland Stanford Junior University | Wnt compositions and methods of use thereof |
CA2716255C (en) * | 2008-02-21 | 2016-11-29 | Dermacare Neuroscience Institute | Cosmetic and dermatological formulations of mntf peptides |
CN105283441B (zh) * | 2013-02-28 | 2018-10-23 | 塔夫茨大学 | 用于递送药剂的二硫化合物 |
US20160082126A1 (en) * | 2013-05-13 | 2016-03-24 | Tufts University | Nanocomplexes for delivery of saporin |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5907030A (en) * | 1995-01-25 | 1999-05-25 | University Of Southern California | Method and compositions for lipidization of hydrophilic molecules |
BR9709993A (pt) * | 1996-06-25 | 1999-08-10 | Stichting Inst Dierhouderij | Vacina preparação de vacina composição processo para produção de uma preparação imugênica e preparação imugênica |
-
1997
- 1997-09-26 EP EP97944483A patent/EP1023316A4/en not_active Ceased
- 1997-09-26 AU AU45967/97A patent/AU737865B2/en not_active Ceased
- 1997-09-26 JP JP51593398A patent/JP2002515883A/ja not_active Ceased
- 1997-09-26 KR KR1019997002543A patent/KR100691315B1/ko not_active IP Right Cessation
- 1997-09-26 CA CA002267179A patent/CA2267179A1/en not_active Abandoned
- 1997-09-26 BR BR9712128-2A patent/BR9712128A/pt not_active Application Discontinuation
- 1997-09-26 IL IL12917797A patent/IL129177A0/xx not_active IP Right Cessation
- 1997-09-26 CN CN97199191A patent/CN1127477C/zh not_active Expired - Fee Related
- 1997-09-26 WO PCT/US1997/017282 patent/WO1998013007A2/en active IP Right Grant
-
1999
- 1999-03-25 NO NO991465A patent/NO991465L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN1127477C (zh) | 2003-11-12 |
WO1998013007A2 (en) | 1998-04-02 |
AU737865B2 (en) | 2001-09-06 |
CN1235594A (zh) | 1999-11-17 |
EP1023316A4 (en) | 2004-06-09 |
WO1998013007A8 (en) | 1999-05-20 |
KR100691315B1 (ko) | 2007-03-12 |
BR9712128A (pt) | 2000-12-12 |
KR20000048608A (ko) | 2000-07-25 |
NO991465L (no) | 1999-05-10 |
EP1023316A2 (en) | 2000-08-02 |
AU4596797A (en) | 1998-04-17 |
NO991465D0 (no) | 1999-03-25 |
CA2267179A1 (en) | 1998-04-02 |
JP2002515883A (ja) | 2002-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |