EP0998280A4 - Carbohydrate scaffold compounds and libraries - Google Patents

Carbohydrate scaffold compounds and libraries

Info

Publication number
EP0998280A4
EP0998280A4 EP19980924946 EP98924946A EP0998280A4 EP 0998280 A4 EP0998280 A4 EP 0998280A4 EP 19980924946 EP19980924946 EP 19980924946 EP 98924946 A EP98924946 A EP 98924946A EP 0998280 A4 EP0998280 A4 EP 0998280A4
Authority
EP
European Patent Office
Prior art keywords
libraries
scaffold compounds
carbohydrate scaffold
carbohydrate
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19980924946
Other languages
German (de)
French (fr)
Other versions
EP0998280A1 (en
Inventor
Tin Yau Chan
Michael J Sofia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aeolus Pharmaceuticals Inc
Original Assignee
Incara Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incara Pharmaceuticals Corp filed Critical Incara Pharmaceuticals Corp
Publication of EP0998280A1 publication Critical patent/EP0998280A1/en
Publication of EP0998280A4 publication Critical patent/EP0998280A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
EP19980924946 1997-05-29 1998-05-28 Carbohydrate scaffold compounds and libraries Withdrawn EP0998280A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4794697P 1997-05-29 1997-05-29
US47946P 1997-05-29
PCT/US1998/010867 WO1998053813A1 (en) 1997-05-29 1998-05-28 Carbohydrate scaffold compounds and libraries

Publications (2)

Publication Number Publication Date
EP0998280A1 EP0998280A1 (en) 2000-05-10
EP0998280A4 true EP0998280A4 (en) 2002-11-06

Family

ID=21951894

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19980924946 Withdrawn EP0998280A4 (en) 1997-05-29 1998-05-28 Carbohydrate scaffold compounds and libraries

Country Status (4)

Country Link
EP (1) EP0998280A4 (en)
JP (1) JP2002502393A (en)
AU (1) AU7700098A (en)
WO (1) WO1998053813A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE478083T1 (en) 1999-03-05 2010-09-15 Massachusetts Inst Technology LINKER FOR THE SYNTHESIS OF OLIGOSACCHARIDES ON SOLID SUPPORTS
AUPS143402A0 (en) * 2002-03-28 2002-05-09 Alchemia Pty Ltd Anomeric derivatives of monosaccharides
AUPS213802A0 (en) 2002-05-03 2002-06-06 Alchemia Pty Ltd Disaccharides for drug discovery
AU2002952121A0 (en) 2002-10-17 2002-10-31 Alchemia Limited Novel carbohydrate based anti-bacterials
AU2003266863B2 (en) * 2002-10-17 2007-03-08 Vast Bioscience Pty Ltd Carbohydrate based anti-bacterials
US7951789B2 (en) 2006-12-28 2011-05-31 Idenix Pharmaceuticals, Inc. Compounds and pharmaceutical compositions for the treatment of viral infections
BR112012024661A2 (en) 2010-04-01 2015-09-15 Centre Nat Rech Scient compound, pharmaceutical composition and method of treating a host infected with hepatitis c virus
WO2012154321A1 (en) 2011-03-31 2012-11-15 Idenix Pharmaceuticals, Inc. Compounds and pharmaceutical compositions for the treatment of viral infections

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07242684A (en) * 1994-03-02 1995-09-19 Japan Tobacco Inc New glucuronic acid compound
US5556836A (en) * 1993-11-08 1996-09-17 Asta Medica Aktiengesellschaft Use of D-glucopyranuronic acids and their derivatives for incorporation in pharmacologically active peptides and their salts

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221754A (en) * 1989-06-09 1993-06-22 Research Corporation Technologies, Inc. Reagents for rapid peptide synthesis
AU675829B2 (en) * 1993-02-23 1997-02-20 Trustees Of Princeton University, The Solution and solid-phase formation of glycosidic linkages
US5773512A (en) * 1994-12-15 1998-06-30 Smithkline Beecham Corp. Compounds and methods
AU697920B2 (en) * 1994-07-26 1998-10-22 Scripps Research Institute, The Soluble combinatorial libraries
US5756712A (en) * 1997-01-23 1998-05-26 E. I. Du Pont De Nemours And Company Peptidodisaccharides as oligosaccharide mimetics

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556836A (en) * 1993-11-08 1996-09-17 Asta Medica Aktiengesellschaft Use of D-glucopyranuronic acids and their derivatives for incorporation in pharmacologically active peptides and their salts
JPH07242684A (en) * 1994-03-02 1995-09-19 Japan Tobacco Inc New glucuronic acid compound

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 111, no. 15, 1989, Columbus, Ohio, US; abstract no. 134731, page 818; column left; XP002217788 *
GOEBEL M ET AL: "Beyond Peptide and Nucleic Acid Combinatorial Libraries-Applying Unions of Multicomponent Reactions towards the Generation of Carbohydrate Combinatorial Libraries", TETRAHEDRON LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 36, no. 34, 1 August 1995 (1995-08-01), pages 6043 - 6046, XP004027444, ISSN: 0040-4039 *
HECKER, J.S. AND MINICH, M.L.: "Synthesis of C(6)-carboxylate analogues of N-acetylmuramic acid", J. ORG. CHEM., vol. 55, no. 24, 1990, pages 6051 - 4, XP001117552 *
KAHNE D: "COMBINATORIAL APPROACHES TO CARBOHYDRATES", CURRENT OPINION IN CHEMICAL BIOLOGY, CURRENT BIOLOGY LTD, LONDON, GB, vol. 1, 1997, pages 130 - 135, XP000884351, ISSN: 1367-5931 *
KHIM. PRIR. SOEDIN., vol. 6, 1988, pages 850 - 5 *
KISS, J. AND BURKHARDT, F.: "Ungesättigte Zucker. Eine milde Sulfonat-beta-Eliminierung bei Aminohexopyranosiduronat-Derivaten", HELV. CHIM. ACTA, vol. 52, no. 8, 1969, pages 2622 - 36, XP001117785 *
PATENT ABSTRACTS OF JAPAN *
PAULSEN, H. AND LORENTZEN, J.P.: "Darstellung von beta-glycosidisch verknüpften Sacchariden der 2-Amino-2-desoxy-D-mannose", CARBOHYDR. RES., vol. 133, 1984, pages C1 - C4, XP001118179 *
See also references of WO9853813A1 *

Also Published As

Publication number Publication date
WO1998053813A1 (en) 1998-12-03
JP2002502393A (en) 2002-01-22
AU7700098A (en) 1998-12-30
EP0998280A1 (en) 2000-05-10

Similar Documents

Publication Publication Date Title
EP1037635A4 (en) Compounds and methods
HUP0100184A3 (en) Substituted 2-benzylamino-2-phenyl-acetamide compounds and pharmaceuticals comprising them
GB2325265B (en) Structural members
EP0998280A4 (en) Carbohydrate scaffold compounds and libraries
EP1008352A4 (en) Brain-protective agent
GB9717209D0 (en) Condition detector
PL321953A1 (en) Scaffolding assembly
GB2326436B (en) Scaffolding unit
EP1032559A4 (en) Aminoalkylphenol derivatives and related compounds
GB2332101B (en) Detector
ZA988492B (en) Substituted tetrahydro-naphthalenes and analogous compounds
GB2325258B (en) Lintels
GB2354538B (en) Structural members
EP1135023A4 (en) Aminobenzisoxazole compounds and libraries thereof
GB2331120B (en) Scaffolding lock
GB2328789B (en) Detectors
PL325807A1 (en) Building unit
GB9503908D0 (en) Compliant structures
MD823F1 (en) Antimutagenous agent
PL319864A1 (en) Scaffolding
GB9718547D0 (en) Smoke detector
AU133284S (en) Cross connection cabinet
PL324152A1 (en) Building unit
GB9701314D0 (en) Locking mechanisms
CA82486S (en) Cross connection cabinet

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19991227

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched
AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RIC1 Information provided on ipc code assigned before grant

Free format text: 7A 61K 31/395 A, 7A 61K 38/00 B, 7C 07D 487/00 B, 7C 07D 487/04 B, 7A 61K 31/70 B, 7C 07H 15/04 B

A4 Supplementary search report drawn up and despatched

Effective date: 20021106

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20030521

REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1026367

Country of ref document: HK