EP0934250A4 - Procede de preparation de composes pharmaceutiques - Google Patents

Procede de preparation de composes pharmaceutiques

Info

Publication number
EP0934250A4
EP0934250A4 EP97941436A EP97941436A EP0934250A4 EP 0934250 A4 EP0934250 A4 EP 0934250A4 EP 97941436 A EP97941436 A EP 97941436A EP 97941436 A EP97941436 A EP 97941436A EP 0934250 A4 EP0934250 A4 EP 0934250A4
Authority
EP
European Patent Office
Prior art keywords
pharmaceutical compounds
prepare pharmaceutical
compounds
prepare
cryptophycin compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97941436A
Other languages
German (de)
English (en)
Other versions
EP0934250A2 (fr
Inventor
Andrew H Fray
Michael J Martinelli
Eric D Moher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Hawaii
Wayne State University
Eli Lilly and Co
Original Assignee
University of Hawaii
Wayne State University
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Hawaii, Wayne State University, Eli Lilly and Co filed Critical University of Hawaii
Publication of EP0934250A2 publication Critical patent/EP0934250A2/fr
Publication of EP0934250A4 publication Critical patent/EP0934250A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Nouveaux composés cryptophycine et procédé de préparation desdits composés.
EP97941436A 1996-09-06 1997-09-05 Procede de preparation de composes pharmaceutiques Withdrawn EP0934250A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2543796P 1996-09-06 1996-09-06
US25437P 1996-09-06
PCT/US1997/015668 WO1998009601A2 (fr) 1996-09-06 1997-09-05 Procede de preparation de composes pharmaceutiques

Publications (2)

Publication Number Publication Date
EP0934250A2 EP0934250A2 (fr) 1999-08-11
EP0934250A4 true EP0934250A4 (fr) 2004-08-11

Family

ID=21826065

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97941436A Withdrawn EP0934250A4 (fr) 1996-09-06 1997-09-05 Procede de preparation de composes pharmaceutiques

Country Status (9)

Country Link
EP (1) EP0934250A4 (fr)
JP (1) JP2001500128A (fr)
KR (1) KR20010029475A (fr)
AU (1) AU4334397A (fr)
BR (1) BR9711695A (fr)
CA (1) CA2264527A1 (fr)
HU (1) HUP0000212A3 (fr)
IL (2) IL128643A0 (fr)
WO (1) WO1998009601A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19911088A1 (de) * 1999-03-12 2000-09-28 Fraunhofer Ges Forschung Manuell geführtes Montagesystem
CA2385528C (fr) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions et methodes de traitement du cancer utilisant des immunoconjugues et des agents chimiotherapeutiques

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995017093A1 (fr) * 1993-12-21 1995-06-29 University Of Hawaii Nouvelles cryptophycines
WO1996040184A1 (fr) * 1995-03-07 1996-12-19 University Of Hawaii Nouvelles cryptophycines obtenues par synthese

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5952298A (en) * 1993-12-21 1999-09-14 The University Of Hawaii Cryptophycins
WO1997008334A1 (fr) * 1995-08-30 1997-03-06 University Of Hawaii Cryptophycines obtenues a partir d'une biosynthese aberrante
AU1469097A (en) * 1995-12-22 1997-07-17 Eli Lilly And Company Pharmaceutical compounds
WO1997031632A1 (fr) * 1996-02-27 1997-09-04 Eli Lilly And Company Composes pharmaceutiques

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995017093A1 (fr) * 1993-12-21 1995-06-29 University Of Hawaii Nouvelles cryptophycines
WO1996040184A1 (fr) * 1995-03-07 1996-12-19 University Of Hawaii Nouvelles cryptophycines obtenues par synthese

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BARROW R A ET AL: "TOTAL SYNTHESIS OF CRYPTOPHYCINS. REVISION OF THE STRUCTURES OF CRYPTOPHYCINS A AND C", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 117, no. 9, 8 March 1995 (1995-03-08), pages 2479 - 2490, XP002066281, ISSN: 0002-7863 *
ISHIHARA K. ET AL.: "Antimony-templated macrolactamization of tetraamino esters.", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY., vol. 118, no. 6, 14 February 1996 (1996-02-14), USAMERICAN CHEMICAL SOCIETY, WASHINGTON, DC., pages 1569 - 1570, XP002283973 *
MENGER F. M. ET AL.: "Anion-catalyzed ester aminolyses in a hydrocarbon solvent", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY., vol. 95, no. 15, 1973, USAMERICAN CHEMICAL SOCIETY, WASHINGTON, DC., pages 4931 - 4934, XP002283974 *
RONY P. R.: "Polyfunctional catalysis. III. Tautomeric catalysis.", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY., vol. 91, no. 22, 1969, USAMERICAN CHEMICAL SOCIETY, WASHINGTON, DC., pages 6090 - 6096, XP002283975 *
WASSERMAN H.H. ET AL.: "Total synthesis of (+-)-Chaenorhine", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY., vol. 105, no. 6, 1983, USAMERICAN CHEMICAL SOCIETY, WASHINGTON, DC., pages 1697 - 1698, XP002283972 *

Also Published As

Publication number Publication date
KR20010029475A (ko) 2001-04-06
AU4334397A (en) 1998-03-26
JP2001500128A (ja) 2001-01-09
HUP0000212A3 (en) 2001-12-28
WO1998009601A2 (fr) 1998-03-12
WO1998009601A3 (fr) 1998-04-23
IL128643A0 (en) 2000-01-31
IL128643A (en) 2006-04-10
BR9711695A (pt) 2000-03-08
EP0934250A2 (fr) 1999-08-11
HUP0000212A2 (en) 2000-07-28
CA2264527A1 (fr) 1998-03-12

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Legal Events

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Effective date: 20040702