EP0688020A1 - Tight junction arrangement between two environment isolated enclosures - Google Patents

Tight junction arrangement between two environment isolated enclosures Download PDF

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Publication number
EP0688020A1
EP0688020A1 EP95401275A EP95401275A EP0688020A1 EP 0688020 A1 EP0688020 A1 EP 0688020A1 EP 95401275 A EP95401275 A EP 95401275A EP 95401275 A EP95401275 A EP 95401275A EP 0688020 A1 EP0688020 A1 EP 0688020A1
Authority
EP
European Patent Office
Prior art keywords
enclosure
flange
door
cam
external
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP95401275A
Other languages
German (de)
French (fr)
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EP0688020B1 (en
Inventor
Bernard Saint Martin
Christiane Lipp-Prioult
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
I D C - Isolateur Denominateur Commun
Original Assignee
I D C - Isolateur Denominateur Commun
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of EP0688020A1 publication Critical patent/EP0688020A1/en
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Publication of EP0688020B1 publication Critical patent/EP0688020B1/en
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00—Enclosures; Chambers
    • B01L1/02—Air-pressure chambers; Air-locks therefor
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
    • G21F7/00—Shielded cells or rooms
    • G21F7/005—Shielded passages through walls; Locks; Transferring devices between rooms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S292/00—Closure fasteners
    • Y10S292/33—Metallic casement window fasteners
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T292/00—Closure fasteners
    • Y10T292/20—Clamps
    • Y10T292/205—Ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T292/00—Closure fasteners
    • Y10T292/20—Clamps
    • Y10T292/225—Cam-operating means

Definitions

  • the invention relates to a sealed junction device between two enclosures normally isolated from an external environment and capable of being put into communication without contact, even momentary, with said external environment.
  • the invention applies more particularly to such a sealed junction device the elements of which are distributed between a mobile or transportable container constituting one of the abovementioned enclosures and a fixed installation designed to be permanently isolated from the external environment and constituting the another aforementioned enclosure, the sealed junction device allowing transfers of objects or fluids between the two enclosures without contamination of or from said external environment.
  • Such a system implements two doors, each of them hermetically closing an opening of the corresponding enclosure delimited by an annular flange.
  • the doors are provided with cooperating assembly means making it possible to apply them one against the other in a hermetic manner, before placing in communication, in order to mutually isolate their external faces.
  • the assembly of the two doors is replaced in the respective housings provided in their flanges and the two enclosures are separated. In this way, the external faces of the two doors cannot be contaminated or contaminating because they had isolated each other during the transfer. They can therefore again be brought into contact with the outside environment.
  • the invention relates to a new concept for such sealed junction devices between two isolated enclosures, applicable to many fields where the products handled are sterile and must be kept sterile, or on the contrary polluting, even dangerous, and must be handled without communication. with the outside environment.
  • the invention therefore relates to a sealed junction device between two enclosures isolated from an external environment and each provided with a door capable of hermetically sealing an opening of the corresponding enclosure delimited by an annular flange, each door being delimited with an internal face in contact with the interior of the enclosure and with an external face in contact with said external medium and said doors being provided with cooperating assembly means making it possible to apply them one against the other so hermetic in order to isolate their external faces mutually, characterized in that one of the two enclosures being of the single-use type, it comprises means for final locking of its own door, controlled by first actuation means installed on the other enclosure.
  • At least part of the wall of said single-use enclosure is made of flexible material and attached directly or indirectly to the rigid annular flange on which the corresponding door is mounted.
  • the entire enclosure except for the flange and the door, will take the form of a bag of flexible material.
  • said single-use enclosure may include means for initial locking of its own door, arranged to be inhibited by second actuation means installed on said other enclosure.
  • FIG. 1 there is partially shown a sealed junction device 11 established between two enclosures 14, 16, the components of the device in question being carried in part by the enclosure 14, which is here a container or a room or any other fixed installation, designed to be permanently isolated from the outside environment and partly by enclosure 16 which is here a simple container of relatively low capacity compared to that of enclosure 14.
  • enclosure 16 is designed as a single-use enclosure. More specifically, the two enclosures 14 and 16 each comprise an aperture 18, 20 bounded by an annular flange 18, 20a, respectively. Each opening 18, 20 is provided with a door 22, 23, respectively. In the example, the flanges have a circular outline, but this is by no means imperative.
  • the sealed junction device is designed to manage the assembly and separation of the doors 22, 23 and the communication of the two enclosures according to a procedure avoiding any contact of the contents of one or the other enclosure with the external environment.
  • the door 22 of the enclosure 14 is defined with an internal face 22 a normally in contact with the interior of the enclosure 14 and in any case never in contact with the outside environment while the door 23 of the enclosure 16 is defined with an internal face 23 a normally in contact with the interior of the enclosure 16 and in any case never in contact with the external environment.
  • the door 22 is defined with an external face 22 b normally in contact with the external environment and in any case never in contact with the interior of one or the other enclosure while the door 23 is defined with a external face 23 b normally in contact with the external environment and in any case never in contact with inside one or the other enclosure.
  • the two doors are provided with cooperating assembly means making it possible to assemble them one against the other in a hermetic manner so as to mutually isolate their external faces 22b , 23b .
  • the door 22 is provided with an annular seal 26 made of elastomeric material on which a projecting external edge of the door 23 is applied.
  • the flange 20 has enclosure for use one 16 is provided at its periphery with an annular seal 27 which abuts on the edge of the flange 18a of the enclosure 14, adjacent the seal 26.
  • the locking elements 28 operating herein by contact are respectively integral with the external faces 22b , 23b , at the centers thereof.
  • These joining elements 28 are for example magnetic or adhesive plates or means using suction cups or other similar elements. Each plate fixed to the center of a door is likely to come to stick against the other. These elements could also be replaced by mechanical systems, for example with hooks.
  • said assembly means are completed by cam mechanisms 25 arranged at the edge of the opening of the enclosure 14.
  • Each mechanism comprises a shaft 24 mounted rotating in the thickness of the flange 18 a and two cams 24A, 24B, respectively exterior and interior, with angularly offset angles of action.
  • the outer cam 24A makes it possible to secure the flange 20 to the chamber for single use to that of the enclosure 14 while the inner cam 24B makes it possible to secure the door 22 of the enclosure 14 to the flange 18 has this one.
  • Each shaft carrying the two aforementioned cams is provided with an operating handle 21.
  • the flange 20 a has an external annular flange 17 provided with three notches 17 a , radial where the external cams 24A are received when approaching the flange 20 a of the flange 18 a .
  • the outer cams 24A extend substantially radially and, as can be seen, the inner cams 24B are in a position such that they firmly hold the door 22 in application against its seat defined in the flange 18 a .
  • the internal cams 24B have flats 25 such that when the handles are rotated, first of all, the external flange 17 of the flange 20 a is made to join against the flange 18 a , before releasing the door 22 by releasing the interior cams.
  • the enclosure 16 is of the single-use type and therefore it comprises means for final locking of its own door 23, controlled by first actuation means installed on the other enclosure.
  • said final locking means comprise at least one arrangement 30 defined in the door 23 and the flange 20 a and comprising a hole 32 passing through the flange 20 a , a blind hole 34 extending in the thickness of the door 23 of the single-use enclosure 16, normally in the extension of the hole 32 of the flange and a pin 36 or the like, engaged in the hole 32 and having a length greater than the thickness of the flange 20 a .
  • said pin 36 projects outside the flange 20 a and is not engaged in the blind hole 34.
  • said first actuation means comprise, in the vicinity of each pin 36, an element 38 forming a shaft, mounted to pivot about its own axis in the flange 18 a , near the edge of the opening 18 of the enclosure 14
  • This shaft is fitted with a cam 37 capable of cooperating with the pin 36 next to it and driving it into the blind hole 34.
  • This element 38 is provided with a handle 39 making it possible to maneuver the cam 37.
  • the single-use enclosure 16 also comprises means for initial locking of its own door 23, arranged to be inhibited by second actuation means installed on the enclosure 14.
  • These initial locking means comprise at least one arrangement 40 defined in the door 23 and the flange 20 a and comprising a hole 42 passing through the flange 20 a , a blind hole 44 extending in the thickness of the door 23 of the disposable enclosure 16, normally in the extension of the hole 42 of the bridle and two pins or anal ogues, respectively an internal pin 46 and an external pin 47 engaged in the extension of one another, in these two holes.
  • two arrangements 40, diametrically opposed, have been provided.
  • the internal pin 46 is engaged both in the flange 20 a and in the door 23 while the external pin 47 projects from the flange 20 a ( Figure 3).
  • the lengths of the pins 46, 47 are such that their ends in contact can come to be placed at the interface of the flange 20 a and the door 23 (FIG. 4) when said second actuation means are exerted on the external pin 47.
  • These second actuation means comprise a cam 48 able to cooperate with the pin 47 to push it into the flange 20 a (FIG. 4).
  • This cam is integral with the same element 38 forming a shaft, provided with a handle 39.
  • said first and second actuation means are combined and distributed over two diametrically opposite assemblies.
  • the flange 17 is provided with cutouts to accommodate the elements 38 and the corresponding cams 37, 48.
  • the pins are mounted so as to guarantee hermetic contact with the walls of the holes in which they are installed, forming kinds of plugs.
  • the fields of the flanges 18 a , 20 a and those of the doors 22, 23 which are mounted therein respectively are conical or have conical portions.
  • the conical portions of the flanges thus form annular seats for said doors.
  • Said conical parts have the same conicity and the diameters of the external faces 22 b , 23 b are equal so that once assembled, the doors have only one conical part without any solution of continuity.
  • the ends of the flanges intended to come into contact have equal diameters so that the conical parts of the flanges are in the extension of one another after assembly and form only one conical section without solution of continuity.
  • the precise circumferential positioning of the flange 20 a with respect to the flange 18 a is ensured by three pins 50 integral with the flange 18 a and distributed circumferentially at 120 °, cooperating with notches 51 formed in the flange 17.
  • One of the pins 50 at least passes through the wall of the flange 18 a and extends inside the enclosure 14.
  • a peripheral flange of the door 22 has a hole 51 or a similar cut, capable of ensuring precise circumferential positioning of the two doors compared to flanges assembled when the two doors are replaced before proceeding to separate the two enclosures.
  • the single-use enclosure 16 or at least part of it is made of flexible material.
  • the part made of flexible material is attached to the rigid annular flange 20 a on which the door 23 is mounted.
  • the enclosure 16 can consist of a simple bag of flexible material connected, for example welded, to the flange 20 a (see Figure 6).
  • the entire enclosure 16 is made up of elements made of inexpensive material.
  • the flange 20a and the door 23 can be made of rigid plastic and the rest of the enclosure (forming the flexible bag) can be made of flexible plastic.
  • the arrangements 30 and 40 of the single-use enclosure have the configuration illustrated in FIG. 3.
  • the lever 39 When the lever 39 is oriented radially, nothing prevents the positioning of the flange 20 a on the flange 18 a and to the assembly of the two doors 22, 23. However the position of the pins 46 prevents opening of the door 23.
  • the operator actuates the three cam mechanisms 25 which has the effect of firmly securing the flange 20 a on the flange 18 a and then unlocking the door 22. Then, the operator rotates the two handles 39 to pass from the situation illustrated in Figure 3 to that shown in Figure 4.
  • FIGS. 8 to 10 illustrate a variant in which the structural elements similar to those of FIGS. 1 to 5 bear the same numerical references increased by 100.
  • This embodiment differs from the previous one in that the assembly means, in particular the cam mechanisms 125 are combined with said first actuation means comprising a cam 137 and with said second actuation means comprising a cam 148. In this way, the connection and locking-unlocking operations are simplified and the risks of error maneuvers are considerably reduced.
  • the cam mechanisms shown in FIG. 1 are reduced to two and grouped with the shafts 138 and the handles 121 of the said first and second actuation means already combined in the previous example.
  • the inner and outer cams which said assembly means included are transferred to the shafts 138, an inner cam 124B being installed at the inner end of each of them and the outer cams here being combined with the cams 148 of said second means d actuation of the above-mentioned initial locking means 140.
  • the cams 148 (or 124A) and 124B are integral with the shaft 138 and have angularly offset action angles as in the previous example, to ensure the same functions.
  • the outer cam 124A are used to secure the flange 120 has the single-use enclosure to that of said other enclosure while the inner cam 124B allow securing the chamber door 114 to the flange thereof.
  • cams 148 are capable of cooperating at the end of the travel, in a direction of rotation of the operating handles 121, with the pins 142 of said initial locking means.
  • each operating handle 121 is not directly linked to the corresponding shaft 138; it is integral with an operating sleeve 160 which covers the shaft 138.
  • This sleeve carries a cam 137 of said first actuation means, capable of cooperating with a pin 136 of said final locking means.
  • the sleeve 160 comprises a coupling light 161 or the like and the shaft 138 comprises a protruding pin 162, extending perpendicular to its axis of rotation and engaged in said coupling light 161.
  • each handle By operating each handle from the neutral position ( Figure 8) to the first extreme position, the operator first causes the single-use enclosure to be attached (by cooperation of the cam 148 with the flange 170), then, at the end of the race, the release of the door of the enclosure 114 and the unlocking of the door 123. After use, the operator maneuvers each handle towards its other extreme position, and the coupling described makes it possible to permanently lock the door 123 of the single-use enclosure before the cam 148 is released from the flange of the single-use enclosure. The same movement causes the enclosure 114 door to be blocked by the cams 124B. To release the single-use enclosure, the operator returns the handles 121 to the neutral position.
  • FIGS. 11 to 22 illustrate mobile single-use enclosures, most often with a flexible wall or part of a wall and with particular characteristics and / or equipment giving the enclosure a specific function.
  • the structural elements similar to those described with reference to Figures 1 to 7 have the same reference numerals.
  • FIG. 11 as a whole represents a single-use enclosure 16 with a flexible wall in the form of a waterproof bag connected to the flange, the latter being closed by the door 23.
  • the flange and the door are equipped with pins allowing first the initial unlocking and later the final and final locking.
  • the part made of flexible material forming a bag can be made of perfectly waterproof plastic, in particular if the enclosure is intended to receive contaminated or polluting products and if it is intended to be destroyed, for example by incineration, with its content.
  • the wall can also be porous, which allows sterilization by autoclaving before or after use.
  • the bag connected to the flange is made of water-soluble material. It is thus possible to recover dirty and / or contaminated clothing, place it in the single-use enclosure and introduce it into a washing machine. The water-soluble bag dissolves there at the start washing and clean clothes can be retrieved at the end of the washing cycle.
  • Figure 12 is similar to that of Figure 11 but a portion 16a only of the flexible wall is made of a porous material adapted to allow sterilization by impregnating a gas such as oxide ethylene. Sterilization is done by placing the enclosure in an atmosphere of ethylene oxide under pressure.
  • a gas such as oxide ethylene
  • the embodiment of Figure 13 also allows sterilization by ethylene oxide.
  • said single-use enclosure comprises a connection end piece 50 for its connection to a source of gaseous ethylene oxide or to another source of sterilization gas.
  • a membrane filter 51 is interposed between the nozzle 50 and the internal volume of the enclosure 16. This filter simultaneously forms a shutter which prevents subsequent contamination of the interior volume of the enclosure.
  • the single-use enclosure consists of a part made of flexible material 16 b and a rigid jar 53.
  • the part made of flexible material is connected in a sealed manner to the jar on the one hand and on the flange 20 a on the other hand.
  • the example of FIG. 15 is that of a bag 55 containing powder.
  • the part made of flexible material comprises at least one tubular sleeve 56 connected between the flange on the one hand and the bag on the other hand. It is also possible that this part is a bag as in the example in FIG. 8 containing another bag, the latter containing the powder. In both cases, the single-use enclosure or the inner bag has an inner sleeve 57 made of flexible material which makes it possible to easily pour the powder.
  • the part which contains the powder is connected to the flange by the sleeve made of flexible material, the connection to the fixed enclosure without being bothered by the often significant weight of the powder bag.
  • FIG. 16 illustrates another embodiment making it possible to transfer a sterilizable solution by filtration.
  • the wall of the single-use enclosure 16 is hermetically traversed by a connecting tube 59 and a filter 60, connected to this tube, is housed in said single-use enclosure.
  • This enclosure can therefore be connected to another fixed enclosure containing the liquid product to be sterilized by filtration, extract this product by filtering it and discard and / or destroy the filter 60 in said single-use enclosure, after transfer.
  • FIG. 17 illustrates another embodiment comprising two flanges 20 a provided with respective doors 23 and respectively connectable to other enclosures 14.
  • the two parts are connected by a tube 63 which forms a element of a fluid circuit. Thanks to this arrangement, it is thus possible to establish a circulation of fluid between two enclosures normally isolated from one another, the double enclosure for single use containing the connection tube 63 being intended to be destroyed after use.
  • FIG. 18 also shows a single-use enclosure comprising two flanges 20a provided with respective doors 23, which can be connected to other fixed enclosures.
  • the flexible material part is connected to the two flanges by its respective ends so that a communication sleeve 65 is thus defined between the two fixed enclosures.
  • the single-use enclosure comprises a flexible duct element 68, the two ends of which open out inside the bag made of flexible material.
  • a U-shaped section of said conduit element extends outside of this bag.
  • This device produces a disposable peristaltic pump element.
  • the two ends of the flexible conduit can be connected to two parts a circuit established inside the fixed enclosure while it is possible to couple the motor and the eccentrics of the peristaltic pump to the part of the flexible conduit which extends outside the bag. After use, the two ends of the flexible conduit are confined to the interior of the single-use enclosure and the assembly can be destroyed.
  • FIG. 20 describes a single-use enclosure which is not provided with a wall made of flexible material but which constitutes an air filter or more generally a single-use gas filter, intended to be connected to a fixed enclosure.
  • the flange 20a is connected by a rigid pipe 69 to a housing 70 containing a dry filter 71, the air filter type, low pressure.
  • Figures 21 and 22 illustrate a last embodiment in which the flexible material part of the single-use enclosure consists of an inverted glove 73 ( Figure 21) connected by the sleeve to a flange 20 a provided with its door 23
  • Figure 21 the flexible material part of the single-use enclosure consists of an inverted glove 73 ( Figure 21) connected by the sleeve to a flange 20 a provided with its door 23
  • the user can introduce his hand into the glove 73 and engage it in the fixed enclosure (FIG. 22) to carry out manipulations there. .

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Pressure Vessels And Lids Thereof (AREA)
  • Lock And Its Accessories (AREA)
  • Packages (AREA)
  • Casings For Electric Apparatus (AREA)
  • Refuse Receptacles (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Connector Housings Or Holding Contact Members (AREA)
  • Non-Flushing Toilets (AREA)
  • Refrigerator Housings (AREA)

Abstract

Chaque enceinte (14,16) comporte une porte (22,23); les deux portes sont munies de moyens d'assemblage coopérants; l'une (16) des enceintes est du type à usage unique et comporte des moyens de verrouillage final (30) de sa propre porte (23), commandés par des moyens d'actionnement (37,39) installés sur l'autre enceinte (14).

Figure imgaf001
Each enclosure (14,16) has a door (22,23); the two doors are provided with cooperating assembly means; one (16) of the speakers is of the single-use type and comprises means for final locking (30) of its own door (23), controlled by actuation means (37,39) installed on the other enclosure (14).
Figure imgaf001

Description

L'invention concerne un dispositif de jonction étanche entre deux enceintes normalement isolées d'un milieu extérieur et susceptibles d'être mises en communication sans contact, même momentané, avec ledit milieu extérieur.The invention relates to a sealed junction device between two enclosures normally isolated from an external environment and capable of being put into communication without contact, even momentary, with said external environment.

L'invention s'applique plus particulièrement à un tel dispositif de jonction étanche dont les éléments sont répartis entre un conteneur mobile ou transportable constituant l'une des enceintes précitées et une installation fixe conçue pour être isolée en permanence du milieu extérieur et constituant l'autre enceinte précitée, le dispositif de jonction étanche permettant des transferts d'objets ou de fluides entre les deux enceintes sans contamination dudit milieu extérieur ou à partir de celui-ci.The invention applies more particularly to such a sealed junction device the elements of which are distributed between a mobile or transportable container constituting one of the abovementioned enclosures and a fixed installation designed to be permanently isolated from the external environment and constituting the another aforementioned enclosure, the sealed junction device allowing transfers of objects or fluids between the two enclosures without contamination of or from said external environment.

On connaît des dispositifs de jonction étanche du genre défini ci-dessus permettant de faire communiquer entre elles deux enceintes étanches, notamment pour des transferts de produits, sans qu'à aucun moment l'étanchéité par rapport au milieu extérieur de chacune des enceintes ou de l'ensemble formé par ces enceintes connectées, ne soit rompue.There are known tight junction devices of the kind defined above making it possible to communicate between them two sealed enclosures, in particular for product transfers, without at any time sealing against the external environment of each of the enclosures or the assembly formed by these connected speakers, is not broken.

Un tel système met en oeuvre deux portes, chacune d'entre elles obturant hermétiquement une ouverture de l'enceinte correspondante délimitée par une bride annulaire. Les portes sont pourvues de moyens d'assemblage coopérants permettant de les appliquer l'une contre l'autre de façon hermétique, avant la mise en communication, afin d'isoler mutuellement leurs faces externes. Après le transfert d'une enceinte vers l'autre, l'ensemble des deux portes est remis en place dans les logements respectifs prévus dans leurs brides et les deux enceintes sont séparées. De cette façon, les faces externes des deux portes ne peuvent être contaminées ou contaminantes du fait qu'elles s'étaient isolées mutuellement pendant le transfert. Elles peuvent donc à nouveau être mises en contact avec le milieu extérieur.Such a system implements two doors, each of them hermetically closing an opening of the corresponding enclosure delimited by an annular flange. The doors are provided with cooperating assembly means making it possible to apply them one against the other in a hermetic manner, before placing in communication, in order to mutually isolate their external faces. After the transfer from one enclosure to the other, the assembly of the two doors is replaced in the respective housings provided in their flanges and the two enclosures are separated. In this way, the external faces of the two doors cannot be contaminated or contaminating because they had isolated each other during the transfer. They can therefore again be brought into contact with the outside environment.

Un tel système est par exemple décrit dans le brevet français N° 1 346 486. Ce document décrit une solution plus particulièrement applicable dans l'industrie nucléaire. Les enceintes mises en communication sont nécessairement coûteuses, compte tenu de l'application envisagée.Such a system is for example described in French patent No. 1,346,486. This document describes a solution more particularly applicable in the nuclear industry. The speakers placed in communication are necessarily expensive, taking into account the envisaged application.

L'invention concerne un nouveau concept pour de tels dispositifs de jonction étanche entre deux enceintes isolées, applicable à de nombreux domaines où les produits manipulés sont stériles et doivent être conservés stériles, ou au contraire polluants, voire dangereux, et doivent être manipulés sans communication avec le milieu extérieur.The invention relates to a new concept for such sealed junction devices between two isolated enclosures, applicable to many fields where the products handled are sterile and must be kept sterile, or on the contrary polluting, even dangerous, and must be handled without communication. with the outside environment.

Plus précisément, l'invention concerne donc un dispositif de jonction étanche entre deux enceintes isolées d'un milieu extérieur et munies, chacune, d'une porte apte à obturer hermétiquement une ouverture de l'enceinte correspondante délimitée par une bride annulaire, chaque porte étant délimitée avec une face interne au contact de l'intérieur de l'enceinte et avec une face externe au contact dudit milieu extérieur et lesdites portes étant pourvues de moyens d'assemblage coopérants permettant de les appliquer l'une contre l'autre de façon hermétique afin d'isoler mutuellement leurs faces externes, caractérisé en ce que l'une des deux enceintes étant du type à usage unique, elle comporte des moyens de verrouillage final de sa propre porte, commandés par des premiers moyens d'actionnement installés sur l'autre enceinte.More specifically, the invention therefore relates to a sealed junction device between two enclosures isolated from an external environment and each provided with a door capable of hermetically sealing an opening of the corresponding enclosure delimited by an annular flange, each door being delimited with an internal face in contact with the interior of the enclosure and with an external face in contact with said external medium and said doors being provided with cooperating assembly means making it possible to apply them one against the other so hermetic in order to isolate their external faces mutually, characterized in that one of the two enclosures being of the single-use type, it comprises means for final locking of its own door, controlled by first actuation means installed on the other enclosure.

Pour de multiples applications, au moins une partie de la paroi de ladite enceinte à usage unique est en matériau souple et rattachée directement ou indirectement à la bride annulaire rigide sur laquelle est montée la porte correspondante.For multiple applications, at least part of the wall of said single-use enclosure is made of flexible material and attached directly or indirectly to the rigid annular flange on which the corresponding door is mounted.

Dans de nombreux cas, c'est l'enceinte entière, hormis la bride et la porte, qui prendra la forme d'un sac en matériau souple.In many cases, the entire enclosure, except for the flange and the door, will take the form of a bag of flexible material.

D'autres équipements de sécurité sont avantageusement prévus et en particulier, ladite enceinte à usage unique peut comporter des moyens de verrouillage initial de sa propre porte, agencés pour être inhibés par des seconds moyens d'actionnement installés sur ladite autre enceinte.Other safety equipment is advantageously provided and in particular, said single-use enclosure may include means for initial locking of its own door, arranged to be inhibited by second actuation means installed on said other enclosure.

L'invention sera mieux comprise et d'autres avantages de celle-ci apparaîtront plus clairement à la lumière de la description qui va suivre d'un mode de réalisation d'un dispositif de jonction étanche conforme à son principe et de plusieurs applications remarquables de ce concept, donnée uniquement à titre d'exemple et faite en référence aux dessins annexés dans lesquels:

  • la figure 1 est une vue de face, avec arrachement partiel, d'un dispositif de jonction étanche entre deux enceintes isolées d'un milieu extérieur et montrant les moyens d'assemblage de l'extérieur d'une enceinte fixe;
  • la figure 2 est une vue analogue à la figure 1, montrant l'assemblage de l'intérieur de cette même enceinte fixe;
  • la figure 3 est une vue à plus grande échelle de l'encadré III de la figure 1;
  • la figue 4 est une vue analogue à la figure 3 illustrant une manoeuvre de libération de la porte de l'enceinte mobile;
  • la figure 5 est une vue analogue à la figure 4 illustrant le verrouillage final de la porte de l'enceinte mobile;
  • la figure 6 est une coupe VI-VI de la figure 1;
  • la figure 7 est une coupe VII-VII de la figure 1;
  • la figure 8 est une vue partielle de face, avec arrachement, d'une variante d'un dispositif de jonction étanche entre deux enceintes isolées d'un milieu extérieur, montrant les moyens d'assemblage et de verrouillage de l'extérieur d'une enceinte fixe;
  • la figure 9 est une vue de détail en coupe partielle illustrant la structure d'une poignée de manoeuvre et des cames associées, du mode de réalisation de la figure 8;
  • la figure 10 est une vue de détail en perspective d'une partie de l'agencement de la figure 9; et
  • les figures 11 à 22 sont des vues très schématiques illustrant un certain nombre d'applications mettant en oeuvre le dispositif de jonction étanche conforme à l'invention.
The invention will be better understood and other advantages thereof will appear more clearly in the light of the following description of an embodiment of a sealed junction device in accordance with its principle and of several remarkable applications of this concept, given solely by way of example and made with reference to the appended drawings in which:
  • Figure 1 is a front view, partially broken away, of a sealed junction device between two enclosures isolated from an external environment and showing the means of assembly from the outside of a fixed enclosure;
  • Figure 2 is a view similar to Figure 1 showing the assembly of the interior of the same fixed enclosure;
  • Figure 3 is an enlarged view of Box III in Figure 1;
  • Fig 4 is a view similar to Figure 3 illustrating a release operation of the door of the movable enclosure;
  • Figure 5 is a view similar to Figure 4 illustrating the final locking of the door of the mobile enclosure;
  • Figure 6 is a section VI-VI of Figure 1;
  • Figure 7 is a section VII-VII of Figure 1;
  • Figure 8 is a partial front view, with cutaway, of a variant of a sealed junction device between two enclosures isolated from an external environment, showing the assembly and locking means from the outside of a fixed enclosure;
  • Figure 9 is a detail view in partial section illustrating the structure of an operating handle and associated cams, of the embodiment of Figure 8;
  • Figure 10 is a detailed perspective view of part of the arrangement of Figure 9; and
  • Figures 11 to 22 are very schematic views illustrating a number of applications using the sealed junction device according to the invention.

En se reportant plus particulièrement aux figures 1 à 7, on a représenté partiellement un dispositif de jonction étanche 11 établi entre deux enceintes 14, 16, les éléments constitutifs du dispositif en question étant portés pour partie par l'enceinte 14, qui est ici un conteneur ou un local ou toute autre installation fixe, conçu pour être isolé en permanence du milieu extérieur et pour partie par l'enceinte 16 qui est ici un simple conteneur de capacité relativement faible comparée à celle de l'enceinte 14. Il est important de noter que l'enceinte 16 est conçue en tant qu'enceinte à usage unique. Plus précisément, les deux enceintes 14 et 16 comportent chacune une ouverture 18, 20 délimitée par une bride annulaire 18a, 20a, respectivement. Chaque ouverture 18, 20 est munie d'une porte 22, 23, respectivement. Dans l'exemple, les brides ont un contour circulaire, mais cela n'est nullement impératif. Le dispositif de jonction étanche est conçu pour gérer l'assemblage et la séparation des portes 22, 23 et la mise en communication des deux enceintes selon une procédure évitant tout contact du contenu de l'une ou l'autre enceinte avec le milieu extérieur. Ainsi, la porte 22 de l'enceinte 14 est définie avec une face interne 22a normalement au contact de l'intérieur de l'enceinte 14 et en tout cas jamais au contact du milieu extérieur tandis que la porte 23 de l'enceinte 16 est définie avec une face interne 23a normalement au contact de l'intérieur de l'enceinte 16 et en tout cas jamais au contact du milieu extérieur. De façon similaire, la porte 22 est définie avec une face extérieure 22b normalement au contact du milieu extérieur et en tout cas jamais au contact de l'intérieur de l'une ou l'autre enceinte tandis que la porte 23 est définie avec une face extérieure 23b normalement au contact du milieu extérieur et en tout cas jamais au contact de l'intérieur de l'une ou l'autre enceinte. Pour ce faire, les deux portes sont pourvues de moyens d'assemblage coopérants permettant de les assembler l'une contre l'autre de façon hermétique afin d'isoler mutuellement leurs faces externes 22b, 23b. Ainsi l'une des portes, ici la porte 22 est munie d'un joint annulaire 26 en matériau élastomère sur lequel vient s'appliquer un bord externe saillant de la porte 23. De plus, la bride 20a de l'enceinte à usage unique 16 est pourvue à sa périphérie d'un joint annulaire 27 venant s'appliquer sur le bord de la bride 18a de l'enceinte 14, au voisinage immédiat du joint 26. Des éléments de solidarisation 28 fonctionnant ici par simple contact sont respectivement solidaires des faces externes 22b, 23b, aux centres de celles-ci. Ces éléments de solidarisation 28 sont par exemple des plaquettes magnétiques ou adhésives ou des moyens utilisant des ventouses ou d'autres éléments analogues. Chaque plaquette fixée au centre d'une porte est susceptible de venir se coller contre l'autre. On pourrait aussi remplacer ces éléments par des systèmes mécaniques, par exemple à crochets. D'autre part, lesdits moyens d'assemblage sont complétés par des mécanismes à cames 25 agencés au bord de l'ouverture de l'enceinte 14. On a prévu trois mécanismes de ce genre répartis à 120° le long de l'ouverture 18. Chaque mécanisme comporte un arbre 24 monté tournant dans l'épaisseur de la bride 18a et deux cames 24A, 24B, respectivement extérieure et intérieure à angles d'action décalés angulairement. La came extérieure 24A permet d'assujettir la bride 20a de l'enceinte à usage unique à celle de l'enceinte 14 tandis que la came intérieure 24B permet d'assujettir la porte 22 de l'enceinte 14 à la bride 18a de celle-ci. Chaque arbre portant les deux cames précitées est muni d'une poignée de manoeuvre 21. La bride 20a comporte une collerette annulaire 17 extérieure munie de trois échancrures 17a, radiales où les cames extérieures 24A viennent se loger lorsqu'on approche la bride 20a de la bride 18a. Dans cette situation, les cames extérieures 24A s'étendent sensiblement radialement et, comme on le voit, les cames intérieures 24B sont dans une position telle qu'elles maintiennent fermement la porte 22 en application contre son siège défini dans la bride 18a. Les cames intérieures 24B comportent des méplats 25 tels que lorsqu'on fait tourner les poignées, on réalise d'abord une solidarisation de la collerette extérieure 17 de la bride 20a contre la bride 18a, avant de libérer la porte 22 par dégagement des cames intérieures.Referring more particularly to Figures 1 to 7, there is partially shown a sealed junction device 11 established between two enclosures 14, 16, the components of the device in question being carried in part by the enclosure 14, which is here a container or a room or any other fixed installation, designed to be permanently isolated from the outside environment and partly by enclosure 16 which is here a simple container of relatively low capacity compared to that of enclosure 14. It is important to note that enclosure 16 is designed as a single-use enclosure. More specifically, the two enclosures 14 and 16 each comprise an aperture 18, 20 bounded by an annular flange 18, 20a, respectively. Each opening 18, 20 is provided with a door 22, 23, respectively. In the example, the flanges have a circular outline, but this is by no means imperative. The sealed junction device is designed to manage the assembly and separation of the doors 22, 23 and the communication of the two enclosures according to a procedure avoiding any contact of the contents of one or the other enclosure with the external environment. Thus, the door 22 of the enclosure 14 is defined with an internal face 22 a normally in contact with the interior of the enclosure 14 and in any case never in contact with the outside environment while the door 23 of the enclosure 16 is defined with an internal face 23 a normally in contact with the interior of the enclosure 16 and in any case never in contact with the external environment. Similarly, the door 22 is defined with an external face 22 b normally in contact with the external environment and in any case never in contact with the interior of one or the other enclosure while the door 23 is defined with a external face 23 b normally in contact with the external environment and in any case never in contact with inside one or the other enclosure. To do this, the two doors are provided with cooperating assembly means making it possible to assemble them one against the other in a hermetic manner so as to mutually isolate their external faces 22b , 23b . Thus one of the doors, here the door 22 is provided with an annular seal 26 made of elastomeric material on which a projecting external edge of the door 23 is applied. In addition, the flange 20 has enclosure for use one 16 is provided at its periphery with an annular seal 27 which abuts on the edge of the flange 18a of the enclosure 14, adjacent the seal 26. the locking elements 28 operating herein by contact are respectively integral with the external faces 22b , 23b , at the centers thereof. These joining elements 28 are for example magnetic or adhesive plates or means using suction cups or other similar elements. Each plate fixed to the center of a door is likely to come to stick against the other. These elements could also be replaced by mechanical systems, for example with hooks. On the other hand, said assembly means are completed by cam mechanisms 25 arranged at the edge of the opening of the enclosure 14. Three mechanisms of this kind have been provided distributed at 120 ° along the opening 18 Each mechanism comprises a shaft 24 mounted rotating in the thickness of the flange 18 a and two cams 24A, 24B, respectively exterior and interior, with angularly offset angles of action. The outer cam 24A makes it possible to secure the flange 20 to the chamber for single use to that of the enclosure 14 while the inner cam 24B makes it possible to secure the door 22 of the enclosure 14 to the flange 18 has this one. Each shaft carrying the two aforementioned cams is provided with an operating handle 21. The flange 20 a has an external annular flange 17 provided with three notches 17 a , radial where the external cams 24A are received when approaching the flange 20 a of the flange 18 a . In this situation, the outer cams 24A extend substantially radially and, as can be seen, the inner cams 24B are in a position such that they firmly hold the door 22 in application against its seat defined in the flange 18 a . The internal cams 24B have flats 25 such that when the handles are rotated, first of all, the external flange 17 of the flange 20 a is made to join against the flange 18 a , before releasing the door 22 by releasing the interior cams.

Il ressort clairement de ce qui précède que, dès lors qu'on commence à raccorder les deux ouvertures, on applique les deux portes l'une contre l'autre, de façon hermétique, sans rotation de l'une par rapport à l'autre et de telle sorte que les deux faces extérieures 22b, 23b qui étaient en contact avec le milieu extérieur, s'isolent mutuellement en ne laissant subsister entre elles qu'un espace laminaire 29 hermétiquement clos (figure 6). Les deux faces 22b, 23b s'isolent de cette façon et les portes restent assemblées tout en pouvant être dégagées ensemble de leurs sièges, de sorte que des échanges deviennent possibles entre les deux enceintes. A la fin de ces opérations, les deux portes sont remises en place ensemble dans leurs ouvertures respectives, avant d'être réassemblées à leurs brides respectives puis séparées.It is clear from the above that, as soon as one begins to connect the two openings, the two doors are applied one against the other, in a hermetic manner, without rotation of one with respect to the other and so that the two external faces 22 b , 23 b which were in contact with the external medium, isolate each other, leaving only a hermetically closed laminar space 29 between them (FIG. 6). The two faces 22 b , 23 b are insulated in this way and the doors remain assembled while being able to be released together from their seats, so that exchanges become possible between the two enclosures. At the end of these operations, the two doors are replaced together in their respective openings, before being reassembled with their respective flanges and then separated.

Comme on l'a indiqué précédemment, l'enceinte 16 est du type à usage unique et de ce fait elle comporte des moyens de verrouillage final de sa propre porte 23, commandés par des premiers moyens d'actionnement installés sur l'autre enceinte. Plus précisément, lesdits moyens de verrouillage final comportent au moins un agencement 30 défini dans la porte 23 et la bride 20a et comprenant un trou 32 traversant la bride 20a, un trou borgne 34 s'étendant dans l'épaisseur de la porte 23 de l'enceinte à usage unique 16, normalement dans le prolongement du trou 32 de la bride et une goupille 36 ou analogue, engagée dans le trou 32 et ayant une longueur supérieure à l'épaisseur de la bride 20a. Comme cela est visible sur la figure 1, on a prévu deux agencements 30 de ce genre, diamétralement opposés. Avant mise en oeuvre desdits moyens de verrouillage final, ladite goupille 36 fait saillie à l'extérieur de la bride 20a et n'est pas engagée dans le trou borgne 34.As previously indicated, the enclosure 16 is of the single-use type and therefore it comprises means for final locking of its own door 23, controlled by first actuation means installed on the other enclosure. More specifically, said final locking means comprise at least one arrangement 30 defined in the door 23 and the flange 20 a and comprising a hole 32 passing through the flange 20 a , a blind hole 34 extending in the thickness of the door 23 of the single-use enclosure 16, normally in the extension of the hole 32 of the flange and a pin 36 or the like, engaged in the hole 32 and having a length greater than the thickness of the flange 20 a . As can be seen in Figure 1, we has provided two arrangements 30 of this kind, diametrically opposed. Before implementing said final locking means, said pin 36 projects outside the flange 20 a and is not engaged in the blind hole 34.

Par ailleurs, lesdits premiers moyens d'actionnement comportent, au voisinage de chaque goupille 36, un élément 38 formant arbre, monté pivotant autour de son propre axe dans la bride 18a, près du bord de l'ouverture 18 de l'enceinte 14. Cet arbre est équipé d'une came 37 apte à coopérer avec la goupille 36 voisine et l'enfoncer dans le trou borgne 34. Cet élément 38 est muni d'une poignée 39 permettant de manoeuvrer la came 37. En outre, l'enceinte à usage unique 16 comporte aussi des moyens de verrouillage initial de sa propre porte 23, agencés pour être inhibés par des seconds moyens d'actionnement installés sur l'enceinte 14. Ces moyens de verrouillage initial comportent au moins un agencement 40 défini dans la porte 23 et la bride 20a et comprenant un trou 42 traversant la bride 20a, un trou borgne 44 s'étendant dans l'épaisseur de la porte 23 de l'enceinte à usage unique 16, normalement dans le prolongement du trou 42 de la bride et deux goupilles ou analogues, respectivement une goupille interne 46 et une goupille externe 47 engagées dans le prolongement l'une de l'autre, dans ces deux trous. Comme précédemment, on a prévu deux agencements 40, diamétralement opposés.Furthermore, said first actuation means comprise, in the vicinity of each pin 36, an element 38 forming a shaft, mounted to pivot about its own axis in the flange 18 a , near the edge of the opening 18 of the enclosure 14 This shaft is fitted with a cam 37 capable of cooperating with the pin 36 next to it and driving it into the blind hole 34. This element 38 is provided with a handle 39 making it possible to maneuver the cam 37. In addition, the single-use enclosure 16 also comprises means for initial locking of its own door 23, arranged to be inhibited by second actuation means installed on the enclosure 14. These initial locking means comprise at least one arrangement 40 defined in the door 23 and the flange 20 a and comprising a hole 42 passing through the flange 20 a , a blind hole 44 extending in the thickness of the door 23 of the disposable enclosure 16, normally in the extension of the hole 42 of the bridle and two pins or anal ogues, respectively an internal pin 46 and an external pin 47 engaged in the extension of one another, in these two holes. As before, two arrangements 40, diametrically opposed, have been provided.

Avant utilisation de l'enceinte à usage unique, la goupille interne 46 est engagée à la fois dans la bride 20a et dans la porte 23 tandis que la goupille externe 47 fait saillie hors de la bride 20a (figure 3). Les longueurs des goupilles 46, 47 sont telles que leurs extrémités en contact puissent venir se placer à l'interface de la bride 20a et de la porte 23 (figure 4) lorsque lesdits seconds moyens d'actionnement s'exercent sur la goupille externe 47. Ces seconds moyens d'actionnement comportent une came 48 apte à coopérer avec la goupille 47 pour l'enfoncer dans la bride 20a (figure 4). Cette came est solidaire du même élément 38 formant arbre, muni d'une poignée 39. Autrement dit, comme cela apparaît clairement sur les figures 1 et 3 à 5, lesdits premier et second moyens d'actionnement sont combinés et répartis sur deux ensembles diamétralement opposés. A ces emplacements, la collerette 17 est pourvue de découpes pour accueillir les éléments 38 et les cames 37, 48 correspondantes. Les goupilles sont montées de façon à garantir un contact hermétique avec les parois des trous dans lesquels elles sont installées, formant des sortes de bouchons.Before using the single-use enclosure, the internal pin 46 is engaged both in the flange 20 a and in the door 23 while the external pin 47 projects from the flange 20 a (Figure 3). The lengths of the pins 46, 47 are such that their ends in contact can come to be placed at the interface of the flange 20 a and the door 23 (FIG. 4) when said second actuation means are exerted on the external pin 47. These second actuation means comprise a cam 48 able to cooperate with the pin 47 to push it into the flange 20 a (FIG. 4). This cam is integral with the same element 38 forming a shaft, provided with a handle 39. In other words, as it clearly appears in FIGS. 1 and 3 to 5, said first and second actuation means are combined and distributed over two diametrically opposite assemblies. At these locations, the flange 17 is provided with cutouts to accommodate the elements 38 and the corresponding cams 37, 48. The pins are mounted so as to guarantee hermetic contact with the walls of the holes in which they are installed, forming kinds of plugs.

Comme on le voit sur la figure 6, les champs des brides 18a, 20a et ceux des portes 22, 23 qui se montent respectivement dans celles-ci sont coniques ou comportent des portions coniques. Les parties coniques des brides forment ainsi des sièges annulaires pour lesdites portes. Lesdites parties coniques ont la même conicité et les diamètres des faces extérieures 22b, 23b sont égaux de sorte qu'une fois assemblées, les portes ne présentent qu'une seule partie conique sans solution de continuité. De même, les extrémités des brides destinées à venir en contact ont des diamètres égaux de sorte que les parties coniques des brides se trouvent dans le prolongement l'une de l'autre après assemblage et ne forment qu'un seul tronçon conique sans solution de continuité. Cette configuration particulière des champs des brides et des portes facilitent le dégagement et la remise en place de la double porte.As can be seen in FIG. 6, the fields of the flanges 18 a , 20 a and those of the doors 22, 23 which are mounted therein respectively are conical or have conical portions. The conical portions of the flanges thus form annular seats for said doors. Said conical parts have the same conicity and the diameters of the external faces 22 b , 23 b are equal so that once assembled, the doors have only one conical part without any solution of continuity. Likewise, the ends of the flanges intended to come into contact have equal diameters so that the conical parts of the flanges are in the extension of one another after assembly and form only one conical section without solution of continuity. This particular configuration of the flange and door fields makes it easier to clear and replace the double door.

Le positionnement circonférentiel précis de la bride 20a par rapport à la bride 18a est assuré par trois pions 50 solidaires de la bride 18a et répartis circonférentiellement à 120°, coopérant avec des échancrures 51 pratiquées dans la collerette 17. L'un des pions 50 au moins traverse la paroi de la bride 18a et s'étend à l'intérieur de l'enceinte 14. Une collerette périphérique de la porte 22 comporte un trou 51 ou une découpe analogue, susceptible d'assurer un positionnement circonférentiel précis des deux portes par rapport aux brides assemblées lorsqu'on remet les deux portes en place avant de procéder aux opérations de séparation des deux enceintes. On est ainsi assuré de replacer les deux trous 32 et 34 de chaque agencement 30 dans le prolongement l'un de l'autre (figure 5) en vue du verrouillage final et définitif de la porte 23 sur la bride 20a de l'enceinte à usage unique 16. La remise en position des deux portes peut être facilitée si l'enceinte 14 est munie d'une manche en matériau souple placée sur le côté de l'ouverture 18 et par laquelle un opérateur peut introduire son bras et manoeuvrer à l'intérieur de l'enceinte 16. La bride 18a est aussi munie d'un levier 54 dont une extrémité est engagée sous la collerette 17 (figure 7) à l'assemblage des deux enceintes, en vue de faciliter ultérieurement le décollement des deux brides, à la séparation desdites enceintes.The precise circumferential positioning of the flange 20 a with respect to the flange 18 a is ensured by three pins 50 integral with the flange 18 a and distributed circumferentially at 120 °, cooperating with notches 51 formed in the flange 17. One of the pins 50 at least passes through the wall of the flange 18 a and extends inside the enclosure 14. A peripheral flange of the door 22 has a hole 51 or a similar cut, capable of ensuring precise circumferential positioning of the two doors compared to flanges assembled when the two doors are replaced before proceeding to separate the two enclosures. It is thus ensured to replace the two holes 32 and 34 of each arrangement 30 in the extension of one another (Figure 5) for the final and final locking of the door 23 on the flange 20 a of the enclosure for single use 16. The positioning of the two doors can be facilitated if the enclosure 14 is provided with a flexible material handle placed on the side of the opening 18 and through which an operator can introduce his arm and maneuver at inside the enclosure 16. the flange 18 a is also provided with a lever 54 whose one end is engaged under the flange 17 (Figure 7) to the assembly of the two enclosures, in order to facilitate later detachment of the two flanges, at the separation of said enclosures.

Selon une autre caractéristique très avantageuse de l'invention, l'enceinte 16 à usage unique ou au moins une partie de celle-ci est en matériau souple. La partie en matériau souple est rattachée à la bride annulaire rigide 20a sur laquelle est montée la porte 23. Dans plusieurs modes de réalisation, l'enceinte 16 peut consister en un simple sac de matériau souple raccordé, par exemple soudé, à la bride 20a (voir figure 6). L'ensemble de l'enceinte 16 est constitué par des éléments en matériau peu coûteux. Par exemple, la bride 20a et la porte 23 peuvent être en matière plastique rigide et le reste de l'enceinte (formant le sac souple) peut être en matière plastique souple.According to another very advantageous characteristic of the invention, the single-use enclosure 16 or at least part of it is made of flexible material. The part made of flexible material is attached to the rigid annular flange 20 a on which the door 23 is mounted. In several embodiments, the enclosure 16 can consist of a simple bag of flexible material connected, for example welded, to the flange 20 a (see Figure 6). The entire enclosure 16 is made up of elements made of inexpensive material. For example, the flange 20a and the door 23 can be made of rigid plastic and the rest of the enclosure (forming the flexible bag) can be made of flexible plastic.

On va maintenant décrire en référence aux figures 3 à 5, les opérations permettant d'accoupler et désaccoupler les deux enceintes.We will now describe with reference to Figures 3 to 5, the operations for coupling and uncoupling the two speakers.

Avant utilisation, les agencements 30 et 40 de l'enceinte à usage unique ont la configuration illustrée à la figure 3. Lorsque le levier 39 est orienté radialement, rien ne s'oppose au positionnement de la bride 20a sur la bride 18a et à l'assemblage des deux portes 22, 23. Cependant la position des goupilles 46 empêche l'ouverture de la porte 23. Avant toute autre manoeuvre, l'opérateur actionne les trois mécanismes à cames 25 ce qui a pour conséquence d'assujettir fermement la bride 20a sur la bride 18a et ensuite de déverrouiller la porte 22. Ensuite, l'opérateur fait pivoter les deux poignées 39 pour passer de la situation illustrée à la figure 3 à celle représentée à la figure 4. A partir de ce moment, le point de contact entre les deux goupilles 46 et 47 se trouve à l'interface de la bride 20a et de la porte 23 et cette dernière peut être désolidarisée de la bride 20a en même temps que la porte 22 avec laquelle elle est assemblée. On peut alors effectuer les opérations souhaitées et notamment les transferts entre les deux enceintes. Après quoi, les deux portes 22 et 23, toujours assemblées, sont remises en place, et l'opérateur fait à nouveau pivoter les poignées 39 pour amener les cames 37 dans la position illustrée à la figure 5, ce qui aboutit à l'enfoncement des goupilles 36 et au verrouillage définitif de la porte 23 sur la bride 20a de l'enceinte 16. Après quoi, il suffit à nouveau de manoeuvrer les mécanismes à cames 25 pour séparer les deux enceintes, chacune étant à nouveau fermée par sa propre porte.Before use, the arrangements 30 and 40 of the single-use enclosure have the configuration illustrated in FIG. 3. When the lever 39 is oriented radially, nothing prevents the positioning of the flange 20 a on the flange 18 a and to the assembly of the two doors 22, 23. However the position of the pins 46 prevents opening of the door 23. Before any other maneuver, the operator actuates the three cam mechanisms 25 which has the effect of firmly securing the flange 20 a on the flange 18 a and then unlocking the door 22. Then, the operator rotates the two handles 39 to pass from the situation illustrated in Figure 3 to that shown in Figure 4. From this moment, the point of contact between the two pins 46 and 47 is at the interface of the flange 20 a and the door 23 and the latter can be detached from the flange 20 a at the same time as the door 22 with which it is assembled. We can then perform the desired operations and in particular transfers between the two speakers. After which, the two doors 22 and 23, still assembled, are put back in place, and the operator again rotates the handles 39 to bring the cams 37 into the position illustrated in FIG. 5, which results in the depression pins 36 and final locking of the door 23 on the flange 20 a of the chamber 16. Thereafter, it is again sufficient to manipulate the cam mechanisms 25 for separating the two chambers each being closed again by its own door.

Les figures 8 à 10 illustrent une variante dans laquelle les éléments de structure analogues à ceux des figures 1 à 5 portent les mêmes références numériques augmentées de 100. Ce mode de réalisation se distingue du précédent par le fait que les moyens d'assemblage, notamment les mécanismes à cames 125 sont combinés auxdits premiers moyens d'actionnement comportant une came 137 et auxdits seconds moyens d'actionnement comportant une came 148. De cette façon, les opérations de raccordement et de verrouillage-déverrouillage sont simplifiées et les risques d'erreur de manoeuvre sont considérablement réduits.FIGS. 8 to 10 illustrate a variant in which the structural elements similar to those of FIGS. 1 to 5 bear the same numerical references increased by 100. This embodiment differs from the previous one in that the assembly means, in particular the cam mechanisms 125 are combined with said first actuation means comprising a cam 137 and with said second actuation means comprising a cam 148. In this way, the connection and locking-unlocking operations are simplified and the risks of error maneuvers are considerably reduced.

Plus précisément, selon l'exemple, les mécanismes à cames représentés sur la figure 1 sont ramenés à deux et regroupés avec les arbres 138 et les poignées 121 desdits premiers et seconds moyens d'actionnement déjà combinés dans l'exemple précédent.More specifically, according to the example, the cam mechanisms shown in FIG. 1 are reduced to two and grouped with the shafts 138 and the handles 121 of the said first and second actuation means already combined in the previous example.

Les cames intérieure et extérieures que comportaient lesdits moyens d'assemblage sont reportés sur les arbres 138, une came intérieure 124B étant installée à l'extrémité intérieure de chacun d'eux et les cames extérieures étant ici confondues avec les cames 148 desdits seconds moyens d'actionnement des moyens de verrouillage initial 140 précités. Les cames 148 (ou 124A) et 124B sont solidaires de l'arbre 138 et ont des angles d'action décalés angulairement comme dans l'exemple précédent, pour assurer les mêmes fonctions. Les cames extérieures 124A permettent d'assujettir la bride 120a de l'enceinte à usage unique à celle de ladite autre enceinte tandis que les cames intérieures 124B permettent d'assujettir la porte de l'enceinte 114 à la bride de celle-ci.The inner and outer cams which said assembly means included are transferred to the shafts 138, an inner cam 124B being installed at the inner end of each of them and the outer cams here being combined with the cams 148 of said second means d actuation of the above-mentioned initial locking means 140. The cams 148 (or 124A) and 124B are integral with the shaft 138 and have angularly offset action angles as in the previous example, to ensure the same functions. The outer cam 124A are used to secure the flange 120 has the single-use enclosure to that of said other enclosure while the inner cam 124B allow securing the chamber door 114 to the flange thereof.

Par ailleurs, les cames 148 sont susceptibles de coopérer en fin de course, dans un sens de rotation des poignées de manoeuvre 121, avec les goupilles 142 desdits moyens de verrouillage initial.Furthermore, the cams 148 are capable of cooperating at the end of the travel, in a direction of rotation of the operating handles 121, with the pins 142 of said initial locking means.

Cependant, chaque poignée de manoeuvre 121 n'est pas directement liée à l'arbre 138 correspondant; elle est solidaire d'un manchon de manoeuvre 160 qui coiffe l'arbre 138. Ce manchon porte une came 137 desdits premiers moyens d'actionnement, susceptible de coopérer avec une goupille 136 desdits moyens de verrouillage final. Le manchon 160 comporte une lumière de couplage 161 ou analogue et l'arbre 138 comporte un pion 162 en saillie, s'étendant perpendiculairement à son axe de rotation et engagé dans ladite lumière de couplage 161. Avec cet agencement particulier, chaque poignée 121 est susceptible de prendre une position neutre et deux positions extrêmes correspondant respectivement au déverrouillage de la porte 123 puis à son verrouillage final. En manoeuvrant chaque poignée de la position neutre (figure 8) à la première position extrême, l'opérateur provoque d'abord le rattachement de l'enceinte à usage unique (par coopération de la came 148 avec la collerette 170), puis, en fin de course, la libération de la porte de l'enceinte 114 et le déverrouillage de la porte 123. Après usage, l'opérateur manoeuvre chaque poignée vers son autre position extrême, et le couplage décrit permet de verrouiller définitivement la porte 123 de l'enceinte à usage unique avant que la came 148 ne soit dégagée de la bride de l'enceinte à usage unique. Le même mouvement entraîne le blocage de la porte de l'enceinte 114 par les cames 124B. Pour dégager l'enceinte à usage unique, l'opérateur replace les poignées 121 en position neutre.However, each operating handle 121 is not directly linked to the corresponding shaft 138; it is integral with an operating sleeve 160 which covers the shaft 138. This sleeve carries a cam 137 of said first actuation means, capable of cooperating with a pin 136 of said final locking means. The sleeve 160 comprises a coupling light 161 or the like and the shaft 138 comprises a protruding pin 162, extending perpendicular to its axis of rotation and engaged in said coupling light 161. With this particular arrangement, each handle 121 is likely to take a neutral position and two extreme positions corresponding respectively to unlocking the door 123 and then to its final locking. By operating each handle from the neutral position (Figure 8) to the first extreme position, the operator first causes the single-use enclosure to be attached (by cooperation of the cam 148 with the flange 170), then, at the end of the race, the release of the door of the enclosure 114 and the unlocking of the door 123. After use, the operator maneuvers each handle towards its other extreme position, and the coupling described makes it possible to permanently lock the door 123 of the single-use enclosure before the cam 148 is released from the flange of the single-use enclosure. The same movement causes the enclosure 114 door to be blocked by the cams 124B. To release the single-use enclosure, the operator returns the handles 121 to the neutral position.

Les figures 11 à 22 illustrent des enceintes mobiles à usage unique, le plus souvent avec une paroi ou une partie de paroi souple et avec des caractéristiques et/ou des équipements particuliers donnant à l'enceinte une fonction propre. Dans ces figures, les éléments de structure analogues à ceux décrits en référence aux figures 1 à 7 portent les mêmes références numériques. Ainsi, la figure 11 représente dans son ensemble une enceinte à usage unique 16 à paroi souple en forme de sac étanche raccordé à la bride, cette dernière étant refermée par la porte 23. Bien entendu, la bride et la porte sont équipées des goupilles permettant d'abord le déverrouillage initial et ultérieurement le verrouillage final et définitif. La partie en matériau souple formant sac peut être en matière plastique parfaitement étanche, notamment si l'enceinte est destinée à recevoir des produits contaminés ou polluants et si elle est destinée à être détruite, par exemple par incinération, avec son contenu. La paroi peut également être poreuse, ce qui permet de réaliser une stérilisation par autoclavage avant ou après utilisation.FIGS. 11 to 22 illustrate mobile single-use enclosures, most often with a flexible wall or part of a wall and with particular characteristics and / or equipment giving the enclosure a specific function. In these figures, the structural elements similar to those described with reference to Figures 1 to 7 have the same reference numerals. Thus, FIG. 11 as a whole represents a single-use enclosure 16 with a flexible wall in the form of a waterproof bag connected to the flange, the latter being closed by the door 23. Of course, the flange and the door are equipped with pins allowing first the initial unlocking and later the final and final locking. The part made of flexible material forming a bag can be made of perfectly waterproof plastic, in particular if the enclosure is intended to receive contaminated or polluting products and if it is intended to be destroyed, for example by incineration, with its content. The wall can also be porous, which allows sterilization by autoclaving before or after use.

Selon une autre variante le sac raccordé à la bride est en matériau hydrosoluble. On peut ainsi récupérer des vêtements sales et/ou contaminés, les placer dans l'enceinte à usage unique et introduire celle-ci dans une machine à laver. Le sac hydrosoluble s'y dissout au début du lavage et on peut récupérer les vêtements propres à la fin du cycle de lavage.According to another variant, the bag connected to the flange is made of water-soluble material. It is thus possible to recover dirty and / or contaminated clothing, place it in the single-use enclosure and introduce it into a washing machine. The water-soluble bag dissolves there at the start washing and clean clothes can be retrieved at the end of the washing cycle.

Le mode de réalisation de la figure 12 est semblable à celui de la figure 11 mais une partie 16a seulement de la paroi souple est réalisée dans un matériau poreux apte à permettre une stérilisation par imprégnation d'un gaz tel que l'oxyde d'éthylène. La stérilisation se fait en plaçant l'enceinte dans une atmosphère d'oxyde d'éthylène sous pression.The embodiment of Figure 12 is similar to that of Figure 11 but a portion 16a only of the flexible wall is made of a porous material adapted to allow sterilization by impregnating a gas such as oxide ethylene. Sterilization is done by placing the enclosure in an atmosphere of ethylene oxide under pressure.

Le mode de réalisation de la figure 13 permet également une stérilisation par oxyde d'éthylène. Dans ce cas, ladite enceinte à usage unique comporte un embout de raccordement 50 pour sa jonction à une source d'oxyde d'éthylène gazeux ou à une autre source de gaz de stérilisation. Un filtre à membrane 51 est intercalé entre l'embout 50 et le volume interne de l'enceinte 16. Ce filtre forme en même temps un obturateur qui empêche une contamination ultérieure du volume intérieur de l'enceinte.The embodiment of Figure 13 also allows sterilization by ethylene oxide. In this case, said single-use enclosure comprises a connection end piece 50 for its connection to a source of gaseous ethylene oxide or to another source of sterilization gas. A membrane filter 51 is interposed between the nozzle 50 and the internal volume of the enclosure 16. This filter simultaneously forms a shutter which prevents subsequent contamination of the interior volume of the enclosure.

Dans l'exemple de la figure 14, l'enceinte à usage unique est constituée d'une partie en matériau souple 16b et d'un bocal rigide 53. La partie en matériau souple se raccorde de façon étanche au bocal d'une part et à la bride 20a d'autre part. On peut ainsi récupérer des objets tranchants ou pointus (bistouris, seringues, etc...) sans risque de perforation de l'enceinte à usage unique.In the example of FIG. 14, the single-use enclosure consists of a part made of flexible material 16 b and a rigid jar 53. The part made of flexible material is connected in a sealed manner to the jar on the one hand and on the flange 20 a on the other hand. We can thus recover sharp or pointed objects (scalpels, syringes, etc.) without risk of perforation of the single-use enclosure.

L'exemple de la figure 15 est celui d'un sac 55 renfermant de la poudre. La partie en matériau souple comporte au moins un manchon tubulaire 56 raccordé entre la bride d'une part et le sac d'autre part. Il est également possible que cette partie soit un sac comme dans l'exemple de la figure 8 renfermant un autre sac, ce dernier contenant la poudre. Dans les deux cas, l'enceinte à usage unique ou le sac intérieur comporte une manche intérieure 57 en matériau souple qui permet de déverser facilement la poudre. Dans cet exemple, il est à noter que, du fait que la partie qui contient la poudre est raccordée à la bride par le manchon en matériau souple, on peut effectuer le raccordement à l'enceinte fixe sans être gêné par le poids, souvent important, du sac de poudre.The example of FIG. 15 is that of a bag 55 containing powder. The part made of flexible material comprises at least one tubular sleeve 56 connected between the flange on the one hand and the bag on the other hand. It is also possible that this part is a bag as in the example in FIG. 8 containing another bag, the latter containing the powder. In both cases, the single-use enclosure or the inner bag has an inner sleeve 57 made of flexible material which makes it possible to easily pour the powder. In this example, it should be noted that, since the part which contains the powder is connected to the flange by the sleeve made of flexible material, the connection to the fixed enclosure without being bothered by the often significant weight of the powder bag.

La figure 16 illustre un autre mode de réalisation permettant de transférer une solution stérilisable par filtration. Pour ce faire, la paroi de l'enceinte à usage unique 16 est traversée de façon hermétique par une tubulure de raccordement 59 et un filtre 60, raccordé à cette tubulure, est logé dans ladite enceinte à usage unique. On peut donc raccorder cette enceinte à une autre enceinte fixe contenant le produit liquide à stériliser par filtration, extraire ce produit en le filtrant et jeter et/ou détruire le filtre 60 dans ladite enceinte à usage unique, après le transfert.FIG. 16 illustrates another embodiment making it possible to transfer a sterilizable solution by filtration. To do this, the wall of the single-use enclosure 16 is hermetically traversed by a connecting tube 59 and a filter 60, connected to this tube, is housed in said single-use enclosure. This enclosure can therefore be connected to another fixed enclosure containing the liquid product to be sterilized by filtration, extract this product by filtering it and discard and / or destroy the filter 60 in said single-use enclosure, after transfer.

La figure 17 illustre un autre mode de réalisation comportant deux brides 20a munies de portes 23 respectives et respectivement raccordables à d'autres enceintes 14. Dans l'exemple de la figure 14, les deux parties sont reliées par un tube 63 qui forme un élément d'un circuit fluidique. Grâce à cet agencement, on peut ainsi établir une circulation de fluide entre deux enceintes normalement isolées l'une de l'autre, la double enceinte à usage unique renfermant le tube de raccordement 63 étant destinée à être détruite après usage.FIG. 17 illustrates another embodiment comprising two flanges 20 a provided with respective doors 23 and respectively connectable to other enclosures 14. In the example of FIG. 14, the two parts are connected by a tube 63 which forms a element of a fluid circuit. Thanks to this arrangement, it is thus possible to establish a circulation of fluid between two enclosures normally isolated from one another, the double enclosure for single use containing the connection tube 63 being intended to be destroyed after use.

L'exemple de la figure 18 montre également une enceinte à usage unique comportant deux brides 20a munies de portes 23 respectives, raccordables à d'autres enceintes fixes. Dans cet exemple, la partie en matériau souple est connectée aux deux brides par ses extrémités respectives de sorte qu'on définit ainsi un manchon de communication 65 entre les deux enceintes fixes.The example in FIG. 18 also shows a single-use enclosure comprising two flanges 20a provided with respective doors 23, which can be connected to other fixed enclosures. In this example, the flexible material part is connected to the two flanges by its respective ends so that a communication sleeve 65 is thus defined between the two fixed enclosures.

Dans l'exemple de la figure 19, l'enceinte à usage unique comporte un élément de conduit souple 68 dont les deux extrémités débouchent à l'intérieur du sac en matériau souple. Un tronçon en U dudit élément de conduit s'étend à l'extérieur de ce sac. Ce dispositif réalise un élément de pompe péristaltique jetable. En effet, les deux extrémités du conduit souple peuvent être connectées à deux parties d'un circuit établi à l'intérieur de l'enceinte fixe tandis qu'il est possible de coupler le moteur et les excentriques de la pompe péristaltique à la partie du conduit souple qui s'étend à l'extérieur du sac. Après usage, les deux extrémités du conduit souple se retrouvent confinées à l'intérieur de l'enceinte à usage unique et l'ensemble peut être détruit.In the example of FIG. 19, the single-use enclosure comprises a flexible duct element 68, the two ends of which open out inside the bag made of flexible material. A U-shaped section of said conduit element extends outside of this bag. This device produces a disposable peristaltic pump element. Indeed, the two ends of the flexible conduit can be connected to two parts a circuit established inside the fixed enclosure while it is possible to couple the motor and the eccentrics of the peristaltic pump to the part of the flexible conduit which extends outside the bag. After use, the two ends of the flexible conduit are confined to the interior of the single-use enclosure and the assembly can be destroyed.

La figure 20 décrit une enceinte à usage unique qui n'est pas munie d'une paroi en matériau souple mais qui constitue un filtre à air ou plus généralement un filtre de gaz à usage unique, destiné à être raccordé à une enceinte fixe. La bride 20a est raccordée par une tubulure rigide 69 à un boîtier 70 renfermant un filtre sec 71, du genre filtre à air, faible pression.FIG. 20 describes a single-use enclosure which is not provided with a wall made of flexible material but which constitutes an air filter or more generally a single-use gas filter, intended to be connected to a fixed enclosure. The flange 20a is connected by a rigid pipe 69 to a housing 70 containing a dry filter 71, the air filter type, low pressure.

Les figures 21 et 22 illustrent un dernier mode de réalisation dans lequel la partie en matériau souple de l'enceinte à usage unique est constituée par un gant 73 retourné (figure 21) raccordé par la manche à une bride 20a munie de sa porte 23. Lorsqu'un tel dispositif est assemblé à l'ouverture d'une autre enceinte fixe 14, l'utilisateur peut introduire sa main dans le gant 73 et l'engager dans l'enceinte fixe (figure 22) pour y procéder à des manipulations.Figures 21 and 22 illustrate a last embodiment in which the flexible material part of the single-use enclosure consists of an inverted glove 73 (Figure 21) connected by the sleeve to a flange 20 a provided with its door 23 When such a device is assembled at the opening of another fixed enclosure 14, the user can introduce his hand into the glove 73 and engage it in the fixed enclosure (FIG. 22) to carry out manipulations there. .

Claims (21)

1- Dispositif de jonction étanche entre deux enceintes (14, 16) isolées d'un milieu extérieur et munies, chacune, d'une porte (22, 23) apte à obturer hermétiquement une ouverture de l'enceinte correspondante délimitée par une bride annulaire (18a, 20a), chaque porte étant définie avec une face interne au contact de l'intérieur de l'enceinte et avec une face externe au contact dudit milieu extérieur et lesdites portes étant pourvues de moyens d'assemblage coopérants permettant de les appliquer l'une contre l'autre de façon hermétique afin d'isoler mutuellement leurs faces externes, caractérisé en ce que l'une (16) des deux enceintes étant du type à usage unique, elle comporte des moyens de verrouillage final (30) de sa propre porte, commandés par des premiers moyens d'actionnement (37, 39) installés sur l'autre enceinte. 1- Sealing device between two enclosures (14, 16) isolated from an external environment and each provided with a door (22, 23) capable of hermetically sealing an opening of the corresponding enclosure delimited by an annular flange (18 a , 20 a ), each door being defined with an internal face in contact with the interior of the enclosure and with an external face in contact with said external medium and said doors being provided with cooperative assembly means making it possible to apply one against the other in a hermetic manner in order to mutually isolate their external faces, characterized in that one (16) of the two enclosures being of the single-use type, it comprises final locking means (30) from its own door, controlled by first actuating means (37, 39) installed on the other enclosure. 2- Dispositif selon la revendication 1, caractérisé en ce qu'au moins une partie de ladite enceinte à usage unique (16) est en matériau souple et rattachée à ladite bride annulaire rigide (20a) sur laquelle est montée la porte (23) correspondante. 2- Device according to claim 1, characterized in that at least a portion of said single-use enclosure (16) is of flexible material and attached to said rigid annular flange (20a) on which is mounted the holder (23) corresponding. 3- Dispositif selon l'une des revendications précédentes, caractérisé en ce que lesdits moyens de verrouillage final comportent au moins un agencement (30) comprenant un trou (32) traversant la bride de ladite enceinte à usage unique, un trou borgne (34) s'étendant dans l'épaisseur de la porte de cette enceinte dans le prolongement du trou de la bride et une goupille (36) ou analogue engagée dans ledit trou de la bride, en ce que cette goupille a une longueur supérieure à l'épaisseur de la bride et fait saillie à l'extérieur de celle-ci avant mise en oeuvre et en ce que lesdits premiers moyens d'actionnement comportent un élément à came pivotante (38) installé près du bord de l'ouverture de l'autre enceinte (14) et conformé et localisé pour coopérer avec ladite goupille. 3- Device according to one of the preceding claims, characterized in that said final locking means comprise at least one arrangement (30) comprising a hole (32) passing through the flange of said single-use enclosure, a blind hole (34) extending in the thickness of the door of this enclosure in the extension of the hole in the flange and a pin (36) or the like engaged in said hole in the flange, in that this pin has a length greater than the thickness of the flange and protrudes outside thereof before implementation and in that said first actuation means comprise a pivoting cam element (38) installed near the edge of the opening of the other enclosure (14) and shaped and located to cooperate with said pin. 4- Dispositif selon l'une des revendications précédentes, caractérisé en ce que ladite enceinte à usage unique comporte en outre des moyens de verrouillage initial (40) de sa propre porte, agencés pour être inhibés par des seconds moyens d'actionnement (48, 39) installés sur ladite autre enceinte. 4- Device according to one of the preceding claims, characterized in that said single-use enclosure further comprises initial locking means (40) of its own door, arranged to be inhibited by second actuation means (48, 39) installed on said other enclosure. 5- Dispositif selon la revendication 4, caractérisé en ce que lesdits moyens de verrouillage initial comportent au moins un agencement (40) comprenant un trou (42) traversant la bride de ladite enceinte à usage unique, un trou borgne (44) s'étendant dans l'épaisseur de la porte de cette enceinte dans le prolongement du trou de la bride et deux goupilles (46, 47) ou analogues, respectivement interne et externe, engagées l'une derrière l'autre dans ces deux trous, la goupille interne (46) étant engagée à la fois dans ladite bride et dans ladite porte et la goupille externe (47) faisant saillie hors de ladite bride avant utilisation et en ce que lesdits seconds moyens d'actionnement comportent au moins un élément à came pivotante (38) installé sur le bord de l'ouverture de l'autre enceinte et conformé pour coopérer avec ladite goupille externe, les longueurs desdites goupilles étant telles que leurs extrémités en contact viennent se placer à l'interface de ladite bride et de ladite porte lorsque lesdits seconds moyens d'actionnement s'exercent sur ladite goupille externe (47). 5- Device according to claim 4, characterized in that said initial locking means comprise at least one arrangement (40) comprising a hole (42) passing through the flange of said single-use enclosure, a blind hole (44) extending in the thickness of the door of this enclosure in the extension of the hole of the flange and two pins (46, 47) or the like, respectively internal and external, engaged one behind the other in these two holes, the internal pin (46) being engaged both in said flange and in said door and the external pin (47) projecting from said flange before use and in that said second actuation means comprise at least one pivoting cam element (38 ) installed on the edge of the opening of the other enclosure and shaped to cooperate with said external pin, the lengths of said pins being such that their ends in contact are placed at the interface of said flange and of said door when said second actuation means are exerted on said external pin (47). 6- Dispositif selon l'ensemble des revendications 3 et 5, caractérisé en ce que lesdits premier et second moyens d'actionnement sont combinés. 6- Device according to all of claims 3 and 5, characterized in that said first and second actuating means are combined. 7- Dispositif selon l'une des revendications précédentes, caractérisé en ce que lesdits moyens d'assemblage comportent des mécanismes à cames (25) solidaires de ladite autre enceinte (14), réparties le long du bord de l'ouverture de celle-ci et comportant deux cames à angles d'action décalés angulairement, une came extérieure (24A) pour assujettir la bride de l'enceinte à usage unique à celle de ladite autre enceinte et une came (24B) intérieure pour assujettir la porte de ladite autre enceinte à la bride de celle-ci. 7- Device according to one of the preceding claims, characterized in that said assembly means comprise cam mechanisms (25) integral with said other enclosure (14), distributed along the edge of the opening thereof and comprising two cams with angularly offset angles of action, an external cam (24A) for securing the flange of the single-use enclosure to that of said other enclosure and a cam (24B) interior for securing the door of said other enclosure to the flange thereof. 8- Dispositif selon l'une des revendications 4 à 6, caractérisé en ce que lesdits moyens d'assemblage (125) sont combinés auxdits premiers et seconds moyens d'actionnement (137, 148). 8- Device according to one of claims 4 to 6, characterized in that said assembly means (125) are combined with said first and second actuating means (137, 148). 9- Dispositif selon la revendication 8, caractérisé en ce que les moyens d'assemblage comportent des mécanismes à cames solidaires de ladite autre enceinte, répartis le long du bord de celle-ci, comportant chacun deux cames (124B, 148) à angles d'action décalés angulairement, une came extérieure (148) pour assujettir la bride de l'enceinte à usage unique à celle de ladite autre enceinte et une came intérieure (124B) pour assujettir la porte de ladite autre enceinte à la bride de celle-ci, en ce que lesdits premiers moyens d'actionnement comportent une came (137) solidaire d'un manchon de manoeuvre coiffant un arbre commun auxdites cames à angles d'action décalés angulairement, en ce que ledit manchon comporte une lumière de couplage (161) ou analogue et en ce que ledit arbre commun comporte un pion (162) en saillie, engagé dans ladite lumière de couplage. 9- Device according to claim 8, characterized in that the assembly means comprise cam mechanisms integral with said other enclosure, distributed along the edge thereof, each comprising two cams (124B, 148) at angles d angularly offset action, an outer cam (148) to secure the flange of the single-use enclosure to that of said other enclosure and an inner cam (124B) to secure the door of said other enclosure to the flange of it , in that said first actuating means comprise a cam (137) integral with an operating sleeve covering a shaft common to said cams with angularly offset angles of action, in that said sleeve comprises a coupling lumen (161) or the like and in that said common shaft comprises a projecting pin (162), engaged in said coupling lumen. 10- Dispositif selon la revendication 9, caractérisé en ce que ladite came extérieure (148) fait aussi partie des seconds moyens d'actionnement précités. 10- Device according to claim 9, characterized in that said outer cam (148) is also part of the aforementioned second actuation means. 11- Dispositif selon l'une des revendications précédentes, caractérisé en ce qu'au moins une partie de paroi de ladite enceinte à usage unique est en matériau poreux propre à permettre un traitement d'autoclavage ou de stérilisation par un gaz tel que par exemple l'oxyde d'éthylène. 11- Device according to one of the preceding claims, characterized in that at least part of the wall of said single-use enclosure is made of porous material suitable for allowing autoclaving treatment or sterilization by a gas such as for example ethylene oxide. 12- Dispositif selon l'une des revendications 1 à 10, caractérisé en ce que ladite enceinte à usage unique comporte un embout de raccordement (50) pour sa jonction à une source de gaz de stérilisation tel que par exemple l'oxyde d'éthylène et en ce qu'un filtre à membrane (51) est intercalé entre cet embout et le volume interne de ladite enceinte. 12- Device according to one of claims 1 to 10, characterized in that said single-use enclosure comprises a connection end piece (50) for its connection to a source of sterilization gas such as for example ethylene oxide and in that a membrane filter (51) is interposed between this nozzle and the internal volume of said enclosure. 13- Dispositif selon l'une des revendications 1 à 10, caractérisé en ce que la paroi de ladite enceinte à usage unique raccordée à ladite bride est en matériau hydrosoluble. 13- Device according to one of claims 1 to 10, characterized in that the wall of said single-use enclosure connected to said flange is made of water-soluble material. 14- Dispositif selon l'une des revendications 1 à 10, caractérisé en ce que ladite enceinte à usage unique comporte une partie rigide, par exemple en forme de bocal (53), ouvrant à l'intérieur de ladite enceinte et une partie souple (16b) formant par exemple manchon, raccordé à ladite bride d'une part et à ladite partie rigide d'autre part. 14- Device according to one of claims 1 to 10, characterized in that said single-use enclosure comprises a rigid part, for example in the form of a jar (53), opening inside said enclosure and a flexible part ( B ) forming, for example, a sleeve, connected to said flange on the one hand and to said rigid part on the other hand. 15- Dispositif selon l'une des revendications 1 à 10, caractérisé en ce qu'au moins une partie de ladite enceinte à usage unique forme un manchon (56) en matériau souple raccordé à ladite bride (20a) et en ce que, ladite enceinte à usage unique comporte en outre une manche intérieure (57) en matériau souple. 15- Device according to one of claims 1 to 10, characterized in that at least part of said single-use enclosure forms a sleeve (56) of flexible material connected to said flange (20 a ) and in that, said single-use enclosure further comprises an inner sleeve (57) made of flexible material. 16- Dispositif selon la revendication 15, caractérisé en ce que la paroi de ladite enceinte à usage unique est traversée de façon hermétique par une tubulure de raccordement (59) et en ce qu'un filtre (60) raccordé à cette tubulure est logé dans ladite enceinte à usage unique. 16- Device according to claim 15, characterized in that the wall of said single-use enclosure is hermetically traversed by a connecting tube (59) and in that a filter (60) connected to this tube is housed in said single-use enclosure. 17- Dispositif selon l'une des revendications 1 à 10, caractérisé en ce que ladite enceinte à usage unique comporte au moins deux brides (20a) munies de portes (23) respectives, respectivement raccordables à d'autres enceintes. 17- Device according to one of claims 1 to 10, characterized in that said enclosure single use comprises at least two flanges (20a) provided with doors (23) respective, respectively connectable to other speakers. 18- Dispositif selon la revendication 17, caractérisé en ce que ladite enceinte à usage unique est composée de deux parties, respectivement équipées d'une bride et d'une porte et en ce que ces deux parties sont reliées par une tubulure (63) formant élément d'un circuit fluidique. 18- Device according to claim 17, characterized in that said single-use enclosure is composed of two parts, respectively equipped with a flange and a door and in that these two parts are connected by a tube (63) forming element of a fluid circuit. 19- Dispositif selon l'une des revendications 1 à 10, caractérisé en ce qu'il comporte un élément de conduit souple (68) dont les deux extrémités débouchent à l'intérieur de ladite enceinte à usage unique et dont un tronçon s'étend à l'extérieur de celle-ci pour être couplé à moteur de pompe péristaltique. 19- Device according to one of claims 1 to 10, characterized in that it comprises a flexible conduit element (68), the two ends of which open inside said single-use enclosure and one of which section extends outside of it to be coupled to the peristaltic pump motor. 20- Dispositif selon l'une des revendications 1 à 10, caractérisé en ce qu'une partie en matériau souple de ladite enceinte à usage unique a la forme d'un gant (73). 20- Device according to one of claims 1 to 10, characterized in that a flexible material part of said single-use enclosure has the shape of a glove (73). 21- Dispositif selon l'une des revendications 1 à 10 , caractérisé en ce que ladite bride (20a) de l'enceinte à usage unique porte un boîtier (70) renfermant un filtre (71). 21- Device according to one of claims 1 to 10, characterized in that said flange (20 a ) of the single-use enclosure carries a housing (70) containing a filter (71).
EP95401275A 1994-06-17 1995-06-01 Tight junction arrangement between two environment isolated enclosures and single use enclosure therefor Expired - Lifetime EP0688020B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9407430A FR2721289B1 (en) 1994-06-17 1994-06-17 Sealed connection device between two enclosures isolated from an external environment.
FR9407430 1994-06-17

Publications (2)

Publication Number Publication Date
EP0688020A1 true EP0688020A1 (en) 1995-12-20
EP0688020B1 EP0688020B1 (en) 1998-09-09

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EP95401275A Expired - Lifetime EP0688020B1 (en) 1994-06-17 1995-06-01 Tight junction arrangement between two environment isolated enclosures and single use enclosure therefor

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US (1) US5853207A (en)
EP (1) EP0688020B1 (en)
JP (1) JP3929511B2 (en)
AT (1) ATE171006T1 (en)
CA (1) CA2151698C (en)
DE (1) DE69504581T2 (en)
ES (1) ES2120695T3 (en)
FR (1) FR2721289B1 (en)

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WO2000036610A1 (en) * 1998-12-11 2000-06-22 Becton Dickinson France Device for linking doors between two chambers insulated from the outside environment
FR2787235A1 (en) * 1998-12-11 2000-06-16 Becton Dickinson France DEVICE FOR LINKING DOORS BETWEEN TWO ENCLOSURES INSULATED FROM THE EXTERNAL ENVIRONMENT
WO2002017332A1 (en) * 2000-08-18 2002-02-28 Glaxosmithkline Biologicals S.A. System for providing communication between the interior and the exterior of a compartment
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US8523436B2 (en) 2007-05-11 2013-09-03 Sartorius Stedim Aseptics Flexible shipping container and manufacturing process
EP2091051A1 (en) 2008-02-12 2009-08-19 JCE Biotechnology Device for watertight connection between two enclosures
WO2011023906A1 (en) 2009-08-26 2011-03-03 Bernard Saint Martin Temporary sealed double-door junction device
US8893914B2 (en) 2009-08-26 2014-11-25 Lourd 'Innov SAS Temporary sealed double-door junction device
FR2951516A1 (en) * 2009-10-20 2011-04-22 Sartorius Stedim Aseptics IMPROVEMENTS IN TRANSFER SYSTEMS BETWEEN AN ENCLOSURE AND A CONTAINER.
WO2011048295A1 (en) 2009-10-20 2011-04-28 Sartorius Stedim Aseptics Improvements to systems for the transfer between a chamber and a container
US9545628B2 (en) 2009-10-20 2017-01-17 Sartorius Stedim Aseptics Systems for the transfer between a chamber and a container
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US9283556B2 (en) 2009-11-23 2016-03-15 Sartorius Stedim Aseptics Tight connection and tight transfer between two housings in view of an aseptic transfer therebetween
WO2011061464A1 (en) 2009-11-23 2011-05-26 Sartorius Stedim Aseptics Housing for tight connection device and aseptic transfer device
US9168520B2 (en) 2009-11-23 2015-10-27 Sartorius Stedim Aseptics Chamber for sealed junction device and aseptic transfer device
WO2011131870A1 (en) 2010-04-20 2011-10-27 Sartorius Stedim Biotech S.A. Sterilizable biopharmaceutical packaging
US9446401B2 (en) 2011-07-29 2016-09-20 Sartorius Stedim Fmt Sas Container for the aseptic transfer of a biopharmaceutical product
US9795956B2 (en) 2011-07-29 2017-10-24 Sartorius Stedium Fmt Sas Container for the aseptic transfer of a biopharmaceutical product
WO2013017765A1 (en) 2011-07-29 2013-02-07 Sartorius Stedim Aseptics Leaktight joining device for the aseptic transfer of a biopharmaceutical product between a chamber and a container
US9440229B2 (en) 2011-07-29 2016-09-13 Sartorius Stedim Fmt Sas Leaktight joining device for the aseptic transfer of a biopharmaceutical product between a chamber and a container
WO2013017766A1 (en) 2011-07-29 2013-02-07 Sartorius Stedim Aseptics Container for the aseptic transfer of a biopharmaceutical product
FR2978363A1 (en) * 2011-07-29 2013-02-01 Sartorius Stedim Aseptics CONTAINER FOR THE ASEPTIC TRANSFER OF A BIOPHARMACEUTICAL PRODUCT.
US9963255B2 (en) 2012-04-24 2018-05-08 Sartorius Stedim Fmt Sas Sterile individual set for producing biopharmaceutical products
WO2013160594A1 (en) 2012-04-24 2013-10-31 Sartorius Stedim Biotech S.A. Sterile individual set for producing biopharmaceutical products
FR3046206A1 (en) * 2015-12-23 2017-06-30 Sartorius Stedim Aseptics METHOD FOR MANUFACTURING A SEALED CONTAINER
WO2017109420A1 (en) * 2015-12-23 2017-06-29 Sartorius Stedim Aseptics Method for manufacturing a sealed container
US10843184B2 (en) 2015-12-23 2020-11-24 Sartorius Stedim Aseptics Method for manufacturing a leaktight container
GB2555145A (en) * 2016-12-22 2018-04-25 Zennex Special Products Ltd Liner interface
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WO2021123636A1 (en) * 2019-12-20 2021-06-24 Abc Transfer Door arrangement fitted to a first enclosed space for reducing contamination risks when a second enclosed space is connected to the first enclosed space
FR3105055A1 (en) * 2019-12-20 2021-06-25 Abc Tranfer DOOR ARRANGEMENT EQUIPPING A FIRST CLOSED VOLUME TO REDUCE THE RISKS OF CONTAMINATION WHEN CONNECTING A SECOND CLOSED VOLUME TO THE FIRST CLOSED VOLUME
US20230219722A1 (en) * 2020-04-28 2023-07-13 Atkins Nuclear Secured Holdings Corporation Container closure device and method of operating the same

Also Published As

Publication number Publication date
DE69504581T2 (en) 1999-04-29
FR2721289A1 (en) 1995-12-22
FR2721289B1 (en) 1996-08-30
JPH0842694A (en) 1996-02-16
US5853207A (en) 1998-12-29
ES2120695T3 (en) 1998-11-01
EP0688020B1 (en) 1998-09-09
CA2151698C (en) 2005-11-29
ATE171006T1 (en) 1998-09-15
DE69504581D1 (en) 1998-10-15
CA2151698A1 (en) 1995-12-18
JP3929511B2 (en) 2007-06-13

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