EP0675723A4 - Therapie utilisant des bisphosphonates et des strogenes en vue de traiter et de prevenir la resorption osseuse. - Google Patents
Therapie utilisant des bisphosphonates et des strogenes en vue de traiter et de prevenir la resorption osseuse.Info
- Publication number
- EP0675723A4 EP0675723A4 EP94905419A EP94905419A EP0675723A4 EP 0675723 A4 EP0675723 A4 EP 0675723A4 EP 94905419 A EP94905419 A EP 94905419A EP 94905419 A EP94905419 A EP 94905419A EP 0675723 A4 EP0675723 A4 EP 0675723A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- bisphosphonate
- treating
- bone loss
- preventing bone
- estrogen therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99641892A | 1992-12-23 | 1992-12-23 | |
US996418 | 1992-12-23 | ||
PCT/US1993/012302 WO1994014455A1 (fr) | 1992-12-23 | 1993-12-17 | Therapie utilisant des bisphosphonates et des ×strogenes en vue de traiter et de prevenir la resorption osseuse |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0675723A1 EP0675723A1 (fr) | 1995-10-11 |
EP0675723A4 true EP0675723A4 (fr) | 1998-08-05 |
Family
ID=25542895
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP94905419A Ceased EP0675723A4 (fr) | 1992-12-23 | 1993-12-17 | Therapie utilisant des bisphosphonates et des strogenes en vue de traiter et de prevenir la resorption osseuse. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0675723A4 (fr) |
JP (1) | JPH08505142A (fr) |
AU (1) | AU5953894A (fr) |
CA (1) | CA2151240A1 (fr) |
WO (1) | WO1994014455A1 (fr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2065313T5 (es) * | 1993-05-15 | 2004-01-01 | Roche Diagnostics Gmbh | Tableta con biodisponibilidad mejorada que contiene acido diclorometilendifosfonico como sustancia activa. |
US5646134A (en) * | 1994-04-21 | 1997-07-08 | Merck & Co., Inc. | Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices |
UA41909C2 (uk) * | 1994-07-22 | 2001-10-15 | Елі Ліллі Енд Компані | Використання комбінації сполук для інгібірування остеопорозу, фармацевтичний препарат |
US5780455A (en) * | 1994-08-24 | 1998-07-14 | Merck & Co., Inc. | Intravenous alendronate formulations |
EP0824341A4 (fr) * | 1995-05-12 | 1999-07-07 | Merck & Co Inc | Prevention des pertes de dnets par l'administration d'alendronate ou de ses sels |
US5545635A (en) * | 1995-05-23 | 1996-08-13 | Eli Lilly And Company | Inhibiting bone loss with equilenin |
US5616571A (en) * | 1995-06-06 | 1997-04-01 | Merck & Co., Inc. | Bisphosphonates prevent bone loss associated with immunosuppressive therapy |
IL120265A0 (en) * | 1996-02-28 | 1997-06-10 | Pfizer | Combination therapy to treat osteoporosis - polyphosphonates or progestins and estrogen agonists |
IL120270A0 (en) * | 1996-02-28 | 1997-06-10 | Pfizer | Combination therapy to treat osteoporosis |
AU712710B2 (en) * | 1996-05-17 | 1999-11-11 | Merck Sharp & Dohme Corp. | Effervescent bisphosphonate formulation |
EP1378234A1 (fr) * | 1996-05-17 | 2004-01-07 | MERCK & CO. INC. | Formulation de bisphosphonate effervescente |
US5853759A (en) * | 1996-05-17 | 1998-12-29 | Merck & Co.. Inc. | Effervescent alendronate formulation |
JP2001507338A (ja) * | 1996-11-25 | 2001-06-05 | メルク エンド カンパニー インコーポレーテッド | 疾患を治療するために同時投与されるアンドロゲン物質とビスホスホン酸物質 |
US6376477B2 (en) | 1996-11-25 | 2002-04-23 | Merck & Co., Inc. | Combination of an agent that binds to the androgen receptor and a bisphosphonic acid in the prevention and/or treatment of diseases involving calcium or phosphate metabolism |
DE19719680A1 (de) | 1997-05-09 | 1998-11-19 | Boehringer Mannheim Gmbh | Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz |
US6555529B1 (en) * | 1997-12-25 | 2003-04-29 | Toray Industries, Inc. | Remedies for intramedullary diseases |
PT1135140E (pt) * | 1998-12-04 | 2005-10-31 | Roche Diagnostics Gmbh | Utilizacao de ibandronato para a promocao da integracao ossea de endoproteses |
EP1210138A4 (fr) * | 1999-04-22 | 2003-05-07 | Hydro Med Sciences Inc | Administration regulee de bisphosphonates |
AUPQ232599A0 (en) * | 1999-08-19 | 1999-09-09 | Royal Alexandra Hospital For Children, The | Drug for treating fractures |
FR2803521B1 (fr) * | 2000-01-12 | 2002-10-25 | Ceva Sante Animale | Utilisation de l'acide tiludronique et de ses derives chez la volaille pour la preparation d'un medicament destine a prevenir et a traiter l'osteoporose |
US7425549B2 (en) * | 2001-02-06 | 2008-09-16 | The Royal Alexandra Hospital For Children | Drug for the treatment of osteonecrosis and for the management of patients at risk of developing osteonecrosis |
WO2002080933A1 (fr) * | 2001-04-03 | 2002-10-17 | The Royal Alexandra Hospital For Children | Medicament a utiliser en matiere de greffe osseuse |
AUPR553701A0 (en) * | 2001-06-07 | 2001-07-12 | Royal Alexandra Hospital For Children, The | A device for the delivery of a drug to a fractured bone |
TWI315982B (en) | 2001-07-19 | 2009-10-21 | Novartis Ag | Combinations comprising epothilones and pharmaceutical uses thereof |
WO2003057136A2 (fr) | 2001-12-24 | 2003-07-17 | Teva Pharmaceutical Industries Ltd. | Forme posologique avec pastille noyau de principe actif enrobee dans un corps annulaire comprime de poudre ou de substance granulaire, et procede et outils pour la production de cette forme posologique |
US7488496B2 (en) | 2002-03-06 | 2009-02-10 | Christer Rosen | Effervescent compositions comprising bisphosphonates and methods related thereto |
EP1508343B1 (fr) * | 2003-08-21 | 2015-11-04 | AddBIO AB | Implant revêtu de bisphosphonate et son procédé de fabrication |
US8940320B2 (en) | 2005-10-27 | 2015-01-27 | Thommen Medical Ag | Dental implant and production method for said implant |
US8882740B2 (en) | 2009-12-23 | 2014-11-11 | Stryker Trauma Gmbh | Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992005187A1 (fr) * | 1990-09-18 | 1992-04-02 | Boehringer Mannheim Gmbh | NOUVEAUX DERIVES DE 17-β-OESTRADIOL, LEUR PROCEDE DE PRODUCTION ET MEDICAMENTS CONTENANT CES COMPOSES |
EP0496520A1 (fr) * | 1991-01-22 | 1992-07-29 | Merck & Co. Inc. | Agents actifs sur les os |
WO1992014474A1 (fr) * | 1991-02-26 | 1992-09-03 | Norwich Eaton Pharmaceuticals, Inc. | Procede de traitement de l'osteoporose |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3623397A1 (de) * | 1986-07-11 | 1988-01-14 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
-
1993
- 1993-12-17 CA CA002151240A patent/CA2151240A1/fr not_active Abandoned
- 1993-12-17 AU AU59538/94A patent/AU5953894A/en not_active Abandoned
- 1993-12-17 EP EP94905419A patent/EP0675723A4/fr not_active Ceased
- 1993-12-17 WO PCT/US1993/012302 patent/WO1994014455A1/fr not_active Application Discontinuation
- 1993-12-17 JP JP6515312A patent/JPH08505142A/ja active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992005187A1 (fr) * | 1990-09-18 | 1992-04-02 | Boehringer Mannheim Gmbh | NOUVEAUX DERIVES DE 17-β-OESTRADIOL, LEUR PROCEDE DE PRODUCTION ET MEDICAMENTS CONTENANT CES COMPOSES |
EP0496520A1 (fr) * | 1991-01-22 | 1992-07-29 | Merck & Co. Inc. | Agents actifs sur les os |
WO1992014474A1 (fr) * | 1991-02-26 | 1992-09-03 | Norwich Eaton Pharmaceuticals, Inc. | Procede de traitement de l'osteoporose |
Non-Patent Citations (2)
Title |
---|
CIMINERA N. ET AL: "Studio Comparativo degli effeti di estrogeni e difosfonati sulla perdita ossea postmenopausale", ANN. OSTET. GINECOL. MED. PERINAT., vol. 113, no. 5, 1992, pages 232 - 237, XP002064831 * |
See also references of WO9414455A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2151240A1 (fr) | 1994-07-07 |
WO1994014455A1 (fr) | 1994-07-07 |
EP0675723A1 (fr) | 1995-10-11 |
JPH08505142A (ja) | 1996-06-04 |
AU5953894A (en) | 1994-07-19 |
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Legal Events
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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17P | Request for examination filed |
Effective date: 19950724 |
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Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
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18R | Application refused |
Effective date: 20031106 |
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