CA2151240A1 - Administration de biophosphonate et d'oestrogene pour le traitement et la prevention de la perte osseuse - Google Patents

Administration de biophosphonate et d'oestrogene pour le traitement et la prevention de la perte osseuse

Info

Publication number
CA2151240A1
CA2151240A1 CA002151240A CA2151240A CA2151240A1 CA 2151240 A1 CA2151240 A1 CA 2151240A1 CA 002151240 A CA002151240 A CA 002151240A CA 2151240 A CA2151240 A CA 2151240A CA 2151240 A1 CA2151240 A1 CA 2151240A1
Authority
CA
Canada
Prior art keywords
estrogen
bisphosphonate
bone
bone loss
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002151240A
Other languages
English (en)
Inventor
Donna T. Whiteford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2151240A1 publication Critical patent/CA2151240A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002151240A 1992-12-23 1993-12-17 Administration de biophosphonate et d'oestrogene pour le traitement et la prevention de la perte osseuse Abandoned CA2151240A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99641892A 1992-12-23 1992-12-23
US996,418 1992-12-23

Publications (1)

Publication Number Publication Date
CA2151240A1 true CA2151240A1 (fr) 1994-07-07

Family

ID=25542895

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002151240A Abandoned CA2151240A1 (fr) 1992-12-23 1993-12-17 Administration de biophosphonate et d'oestrogene pour le traitement et la prevention de la perte osseuse

Country Status (5)

Country Link
EP (1) EP0675723A4 (fr)
JP (1) JPH08505142A (fr)
AU (1) AU5953894A (fr)
CA (1) CA2151240A1 (fr)
WO (1) WO1994014455A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2065313T5 (es) * 1993-05-15 2004-01-01 Roche Diagnostics Gmbh Tableta con biodisponibilidad mejorada que contiene acido diclorometilendifosfonico como sustancia activa.
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
UA41909C2 (uk) * 1994-07-22 2001-10-15 Елі Ліллі Енд Компані Використання комбінації сполук для інгібірування остеопорозу, фармацевтичний препарат
US5780455A (en) * 1994-08-24 1998-07-14 Merck & Co., Inc. Intravenous alendronate formulations
EP0824341A4 (fr) * 1995-05-12 1999-07-07 Merck & Co Inc Prevention des pertes de dnets par l'administration d'alendronate ou de ses sels
US5545635A (en) * 1995-05-23 1996-08-13 Eli Lilly And Company Inhibiting bone loss with equilenin
US5616571A (en) * 1995-06-06 1997-04-01 Merck & Co., Inc. Bisphosphonates prevent bone loss associated with immunosuppressive therapy
IL120265A0 (en) * 1996-02-28 1997-06-10 Pfizer Combination therapy to treat osteoporosis - polyphosphonates or progestins and estrogen agonists
IL120270A0 (en) * 1996-02-28 1997-06-10 Pfizer Combination therapy to treat osteoporosis
AU712710B2 (en) * 1996-05-17 1999-11-11 Merck Sharp & Dohme Corp. Effervescent bisphosphonate formulation
EP1378234A1 (fr) * 1996-05-17 2004-01-07 MERCK & CO. INC. Formulation de bisphosphonate effervescente
US5853759A (en) * 1996-05-17 1998-12-29 Merck & Co.. Inc. Effervescent alendronate formulation
JP2001507338A (ja) * 1996-11-25 2001-06-05 メルク エンド カンパニー インコーポレーテッド 疾患を治療するために同時投与されるアンドロゲン物質とビスホスホン酸物質
US6376477B2 (en) 1996-11-25 2002-04-23 Merck & Co., Inc. Combination of an agent that binds to the androgen receptor and a bisphosphonic acid in the prevention and/or treatment of diseases involving calcium or phosphate metabolism
DE19719680A1 (de) 1997-05-09 1998-11-19 Boehringer Mannheim Gmbh Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz
US6555529B1 (en) * 1997-12-25 2003-04-29 Toray Industries, Inc. Remedies for intramedullary diseases
PT1135140E (pt) * 1998-12-04 2005-10-31 Roche Diagnostics Gmbh Utilizacao de ibandronato para a promocao da integracao ossea de endoproteses
EP1210138A4 (fr) * 1999-04-22 2003-05-07 Hydro Med Sciences Inc Administration regulee de bisphosphonates
AUPQ232599A0 (en) * 1999-08-19 1999-09-09 Royal Alexandra Hospital For Children, The Drug for treating fractures
FR2803521B1 (fr) * 2000-01-12 2002-10-25 Ceva Sante Animale Utilisation de l'acide tiludronique et de ses derives chez la volaille pour la preparation d'un medicament destine a prevenir et a traiter l'osteoporose
US7425549B2 (en) * 2001-02-06 2008-09-16 The Royal Alexandra Hospital For Children Drug for the treatment of osteonecrosis and for the management of patients at risk of developing osteonecrosis
WO2002080933A1 (fr) * 2001-04-03 2002-10-17 The Royal Alexandra Hospital For Children Medicament a utiliser en matiere de greffe osseuse
AUPR553701A0 (en) * 2001-06-07 2001-07-12 Royal Alexandra Hospital For Children, The A device for the delivery of a drug to a fractured bone
TWI315982B (en) 2001-07-19 2009-10-21 Novartis Ag Combinations comprising epothilones and pharmaceutical uses thereof
WO2003057136A2 (fr) 2001-12-24 2003-07-17 Teva Pharmaceutical Industries Ltd. Forme posologique avec pastille noyau de principe actif enrobee dans un corps annulaire comprime de poudre ou de substance granulaire, et procede et outils pour la production de cette forme posologique
US7488496B2 (en) 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
EP1508343B1 (fr) * 2003-08-21 2015-11-04 AddBIO AB Implant revêtu de bisphosphonate et son procédé de fabrication
US8940320B2 (en) 2005-10-27 2015-01-27 Thommen Medical Ag Dental implant and production method for said implant
US8882740B2 (en) 2009-12-23 2014-11-11 Stryker Trauma Gmbh Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE4029499A1 (de) * 1990-09-18 1992-03-19 Boehringer Mannheim Gmbh Neue 17-(beta)-oestradiolderivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
EP0496520A1 (fr) * 1991-01-22 1992-07-29 Merck & Co. Inc. Agents actifs sur les os
HU215124B (hu) * 1991-02-26 1998-09-28 Norwich Eaton Pharmaceuticals, Inc. Eljárás csontritkulás (osteoporosis) kezelésére szolgáló ösztrogént és difoszfonátot tartalmazó, szinergetikus hatású gyógyszerkészítmények előállítására

Also Published As

Publication number Publication date
WO1994014455A1 (fr) 1994-07-07
EP0675723A4 (fr) 1998-08-05
EP0675723A1 (fr) 1995-10-11
JPH08505142A (ja) 1996-06-04
AU5953894A (en) 1994-07-19

Similar Documents

Publication Publication Date Title
CA2151240A1 (fr) Administration de biophosphonate et d'oestrogene pour le traitement et la prevention de la perte osseuse
EP0756483B1 (fr) Emploi de biphosphonates inhibant la resorption osseuse consecutive a l'implantation d'une prothese orthopedique
EP0635270B1 (fr) Hormone parathyroide et raloxifène pour augmenter la masse d'os
JP2002529490A (ja) 歯牙吸収性病変の阻害方法
JP4989811B2 (ja) 副甲状腺ホルモンおよび骨吸収抑制剤を含む複合型薬学的製剤
AU5973496A (en) Bisphosphonate cement composition to prevent aseptic loosening of orthopedic implant devices
US6399592B1 (en) Bishphosphonate/estrogen synergistic therapy for treating and preventing bone loss
US6376477B2 (en) Combination of an agent that binds to the androgen receptor and a bisphosphonic acid in the prevention and/or treatment of diseases involving calcium or phosphate metabolism
JP2002526412A (ja) 跛行を処置するための医薬品製剤の製造におけるビスホスホン酸誘導体の使用
EA000677B1 (ru) Способ предотвращения остеопороза
CA2271664A1 (fr) Agents androgene et bisphosphonique coadministres pour traiter des maladies
AU2005203308A1 (en) Use of bisphosphonates for inhibiting bone resorption following implantation of orthopaedic prosthesis
AU9745901A (en) Use of bisphosphonates for inhibiting bone resorption following implantation of orthopaedic prosthesis
AU3574799A (en) Use of biphosphonates for inhibiting bone resorption following implantation of orthopedic prosthesis
MXPA96004968A (en) Use of bisphosphonates to inhibit bone rebassion after the implantation of orthopedic protesis
Forde Pharmacological Intervention in the Treatment of Osteoporosis: What's Old and What's New
MXPA97001526A (en) Combined therapy to treat osteoporo

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead