EP0660925A4 - Alkoxyamide derivatized chelates for mri. - Google Patents

Alkoxyamide derivatized chelates for mri.

Info

Publication number: EP0660925A4
Authority: EP; European Patent Office
Prior art keywords: alkoxyamide; chelates; derivatized; mri; derivatized chelates
Prior art date: 1990-11-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP19920902010

Other languages

German (de)

French (fr)

Other versions

EP0660925A1 (en

Inventor

Raghavan Rajagopalan

Rebecca A Wallace

Muthanadar P Periasamy

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Mallinckrodt Inc

Original Assignee

Mallinckrodt Medical Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-11-21

Filing date

1991-11-12

Publication date

1994-02-02

1991-11-12 Application filed by Mallinckrodt Medical Inc filed Critical Mallinckrodt Medical Inc

1994-02-02 Publication of EP0660925A4 publication Critical patent/EP0660925A4/en

1995-07-05 Publication of EP0660925A1 publication Critical patent/EP0660925A1/en

Status Withdrawn legal-status Critical Current

Links

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations

Landscapes

Health & Medical Sciences (AREA)
Physics & Mathematics (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Radiology & Medical Imaging (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Signal Processing (AREA)
Epidemiology (AREA)
High Energy & Nuclear Physics (AREA)
Condensed Matter Physics & Semiconductors (AREA)
General Physics & Mathematics (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

EP92902010A 1990-11-21 1991-11-12 Alkoxyamide derivatized chelates for mri Withdrawn EP0660925A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US61645990A	1990-11-21	1990-11-21
PCT/US1991/008431 WO1992009884A1 (en)	1990-11-21	1991-11-12	Alkoxyamide derivatized chelates for mri
US616459		2003-07-09

Publications (2)

Publication Number	Publication Date
EP0660925A4 true EP0660925A4 (en)	1994-02-02
EP0660925A1 EP0660925A1 (en)	1995-07-05

Family

ID=24469557

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP92902010A Withdrawn EP0660925A1 (en)	1990-11-21	1991-11-12	Alkoxyamide derivatized chelates for mri

Country Status (5)

Country	Link
EP (1)	EP0660925A1 (en)
JP (1)	JPH06502858A (en)
AU (1)	AU656355B2 (en)
CA (1)	CA2096543A1 (en)
WO (1)	WO1992009884A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU675013B2 (en) *	1993-09-14	1997-01-16	University Of Toledo, The	Second sphere complexes as relaxation agents for image enhancement in magnetic resonance imaging
US6693190B1 (en)	1994-05-11	2004-02-17	Bracco International B.V.	Enhanced relaxivity monomeric and multimeric compounds
US6294152B1 (en)	1999-01-11	2001-09-25	The University Of Toledo	Iron(III) complexes as contrast agents for image enhancement in magnetic resonance imaging
EP3101012A1 (en)	2015-06-04	2016-12-07	Bayer Pharma Aktiengesellschaft	New gadolinium chelate compounds for use in magnetic resonance imaging
KR102464647B1 (en)	2016-11-28	2022-11-08	바이엘 파마 악티엔게젤샤프트	High Relaxation Gadolinium Chelate Compounds for Use in Magnetic Resonance Imaging
BR112021007707A2 (en)	2018-11-23	2021-07-27	Bayer Aktiengesellschaft	formulation of contrast media and its preparation process

Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0255471A1 (en) *	1986-07-28	1988-02-03	Schering Aktiengesellschaft	1,4,7,10-Tetraazacyclododecane-derivatives
WO1990001024A1 (en) *	1988-07-19	1990-02-08	Mallinckrodt, Inc.	Novel magnetic resonance imaging agents
WO1990003804A1 (en) *	1988-09-27	1990-04-19	Salutar, Inc.	Chelate compositions
WO1991003261A1 (en) *	1989-09-05	1991-03-21	Mallinckrodt, Inc.	Novel magnetic resonance imaging agents
WO1992002259A1 (en) *	1990-08-03	1992-02-20	Mallinckrodt Medical, Inc.	Novel compositions for magnetic resonance imaging
WO1993002045A1 (en) *	1991-07-17	1993-02-04	Nycomed Salutar, Inc.	Hydroxamate and hydrazide derivatives of polyamines and their medical use as chelating agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4647447A (en) *	1981-07-24	1987-03-03	Schering Aktiengesellschaft	Diagnostic media
US4826673A (en) *	1985-01-09	1989-05-02	Mallinckrodt, Inc.	Methods and compositions for enhancing magnetic resonance imaging
JPS61196319A (en) *	1985-02-27	1986-08-30	Hitachi Ltd	Menu selection system of display device
JPS62293339A (en) *	1986-06-12	1987-12-19	Mitsubishi Electric Corp	Method for transforming menu into hierarchy in computer system
JPH01144760A (en) *	1987-11-30	1989-06-07	Ricoh Co Ltd	Composite system
JPH01191559A (en) *	1988-01-27	1989-08-01	Nec Corp	Complex terminal system

1991
- 1991-11-12 EP EP92902010A patent/EP0660925A1/en not_active Withdrawn
- 1991-11-12 CA CA002096543A patent/CA2096543A1/en not_active Abandoned
- 1991-11-12 WO PCT/US1991/008431 patent/WO1992009884A1/en not_active Application Discontinuation
- 1991-11-12 AU AU90810/91A patent/AU656355B2/en not_active Ceased
- 1991-11-12 JP JP4501072A patent/JPH06502858A/en active Pending

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0255471A1 (en) *	1986-07-28	1988-02-03	Schering Aktiengesellschaft	1,4,7,10-Tetraazacyclododecane-derivatives
WO1990001024A1 (en) *	1988-07-19	1990-02-08	Mallinckrodt, Inc.	Novel magnetic resonance imaging agents
WO1990003804A1 (en) *	1988-09-27	1990-04-19	Salutar, Inc.	Chelate compositions
WO1991003261A1 (en) *	1989-09-05	1991-03-21	Mallinckrodt, Inc.	Novel magnetic resonance imaging agents
WO1992002259A1 (en) *	1990-08-03	1992-02-20	Mallinckrodt Medical, Inc.	Novel compositions for magnetic resonance imaging
WO1993002045A1 (en) *	1991-07-17	1993-02-04	Nycomed Salutar, Inc.	Hydroxamate and hydrazide derivatives of polyamines and their medical use as chelating agents

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
J. CHEM. SOC. PERKIN TRANS. 2 August 1990, pages 1425 - 1432 R. KATAKY ET AL. 'SYNTHESIS AND BINDING PROPERTIES OF AMIDE-FUNCTIONALISED POLYAZA MACROCYCLES' * *
See also references of WO9209884A1 *

Also Published As

Publication number	Publication date
EP0660925A1 (en)	1995-07-05
CA2096543A1 (en)	1992-05-22
AU9081091A (en)	1992-06-25
WO1992009884A1 (en)	1992-06-11
AU656355B2 (en)	1995-02-02
JPH06502858A (en)	1994-03-31

Legal Events

Date	Code	Title	Description
1995-05-19	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1995-07-05	17P	Request for examination filed	Effective date: 19930525
1995-07-05	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE
2000-02-09	17Q	First examination report despatched	Effective date: 19991228
2000-10-13	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2000-11-29	18D	Application deemed to be withdrawn	Effective date: 20000509

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