EP0651650A4 - PROCEDE POUR TRAITER DES AFFECTIONS OPHTALMIQUES A L'AIDE DU FACTEUR TRANSFORMANT DE CROISSANCE--g(b). - Google Patents

PROCEDE POUR TRAITER DES AFFECTIONS OPHTALMIQUES A L'AIDE DU FACTEUR TRANSFORMANT DE CROISSANCE--g(b).

Info

Publication number
EP0651650A4
EP0651650A4 EP93917021A EP93917021A EP0651650A4 EP 0651650 A4 EP0651650 A4 EP 0651650A4 EP 93917021 A EP93917021 A EP 93917021A EP 93917021 A EP93917021 A EP 93917021A EP 0651650 A4 EP0651650 A4 EP 0651650A4
Authority
EP
European Patent Office
Prior art keywords
tgf
ophthalmic disorders
treating ophthalmic
treating
disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP93917021A
Other languages
German (de)
English (en)
Other versions
EP0651650A1 (fr
Inventor
Bert M Glaser
Bruce B Pharriss
Ann F Hanham
George A Ksander
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celtrix Pharmaceuticals Inc
Original Assignee
Celtrix Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celtrix Pharmaceuticals Inc filed Critical Celtrix Pharmaceuticals Inc
Publication of EP0651650A1 publication Critical patent/EP0651650A1/fr
Publication of EP0651650A4 publication Critical patent/EP0651650A4/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EP93917021A 1992-07-08 1993-07-08 PROCEDE POUR TRAITER DES AFFECTIONS OPHTALMIQUES A L'AIDE DU FACTEUR TRANSFORMANT DE CROISSANCE--g(b). Ceased EP0651650A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US91083492A 1992-07-08 1992-07-08
US910834 1992-07-08
US877893A 1993-01-22 1993-01-22
US8778 1993-01-22
PCT/US1993/006420 WO1994001124A1 (fr) 1992-07-08 1993-07-08 PROCEDE POUR TRAITER DES AFFECTIONS OPHTALMIQUES A L'AIDE DU FACTEUR TRANSFORMANT DE CROISSANCE-$g(b)

Publications (2)

Publication Number Publication Date
EP0651650A1 EP0651650A1 (fr) 1995-05-10
EP0651650A4 true EP0651650A4 (fr) 1996-04-17

Family

ID=26678611

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93917021A Ceased EP0651650A4 (fr) 1992-07-08 1993-07-08 PROCEDE POUR TRAITER DES AFFECTIONS OPHTALMIQUES A L'AIDE DU FACTEUR TRANSFORMANT DE CROISSANCE--g(b).

Country Status (5)

Country Link
EP (1) EP0651650A4 (fr)
JP (1) JPH08502033A (fr)
AU (1) AU4668193A (fr)
CA (1) CA2138644A1 (fr)
WO (1) WO1994001124A1 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688765A (en) * 1992-04-21 1997-11-18 The Schepens Eye Research Institute, Inc. Ocular therapy in Sjogren's syndrome using topically applied androgensor TGF-β
US5449671A (en) * 1993-09-29 1995-09-12 Alcon Laboratories, Inc. Use of TGF-β3, to prevent or retard fistula closure following glaucoma filtration surgery
AU7846894A (en) * 1993-09-29 1995-04-18 Alcon Laboratories, Inc. Compositions containing growth factors and antiplastic agents
US5411940A (en) * 1993-09-29 1995-05-02 Alcon Laboratories, Inc. Use of TGF-β3 to reduce the formation of scar tissue in response to corneal trauma
CA2149528A1 (fr) * 1993-09-29 1995-04-06 Billie M. York Compositions contenant des facteurs de croissance et des antimetabolites
JPH09505057A (ja) * 1993-11-19 1997-05-20 ザ・ユニバーシティ・オブ・シドニー 白内障を予防または制御するための方法
AU688409B2 (en) * 1993-11-19 1998-03-12 University Of Sydney, The A method for preventing or controlling cataract
US5827702A (en) * 1994-10-31 1998-10-27 Genentech, Inc. Ocular gene therapy
WO2000053760A2 (fr) * 1999-03-12 2000-09-14 Genentech, Inc. Technique permettant de prevenir la mort des neurones retiniens et traitement des maladies oculaires
US6071875A (en) * 1996-12-04 2000-06-06 Alcon Laboratories, Inc. TGFα for the treatment of ocular hypertension and glaucoma
WO1999005278A1 (fr) * 1997-07-23 1999-02-04 Brigham & Women's Hospital, Inc. Facteur de croissance des cellules epitheliales derive du cristallin
US6750052B1 (en) 1997-07-23 2004-06-15 The Brigham And Women's Hospital, Inc. Lens epithelial cell derived growth factor
US6331523B1 (en) 1998-03-12 2001-12-18 Genentech, Inc. Method of enhancing the survival of retinal neurons and treating ocular diseases using FGF-5
KR100698449B1 (ko) * 1998-11-23 2007-03-23 노파르티스 아게 안구 혈관신생 질환 치료용 스타우로스포린 유도체의 용도
AU6391000A (en) * 1999-07-28 2001-02-19 Genentech Inc. Method of preventing the injury or death of retinal cells and treating ocular diseases
AU2001228863A1 (en) * 2000-01-31 2001-08-14 Santen Pharmaceutical Co. Ltd. Remedies for ophthalmic diseases
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
CN104884049A (zh) 2012-11-08 2015-09-02 克莱尔塞德生物医学股份有限公司 用于在人类受试者中治疗眼部疾病的方法和装置
CN110302004B (zh) 2013-05-03 2023-04-28 科尼尔赛德生物医学公司 用于眼部注射的设备和方法
RU2540504C1 (ru) * 2013-12-26 2015-02-10 Федеральное государственное бюджетное учреждение "Московский научно-исследовательский институт глазных болезней имени Гельмгольца" Министерства здравоохранения Российской Федерации Способ прогнозирования риска развития поздней отслойки сетчатки у детей с рубцовой ретинопатией недоношенных
WO2015142855A1 (fr) * 2014-03-17 2015-09-24 University Of Virginia Patent Foundation Compositions et méthodes destinées à traiter la rétinopathie
US9844556B2 (en) 2015-03-25 2017-12-19 Megumi Honjo Preventive/therapeutic method and preventive/therapeutic agent for complications after cataract surgery
WO2017139375A1 (fr) 2016-02-10 2017-08-17 Clearside Biomedical, Inc. Kit d'injection oculaire, conditionnement et procédés d'utilisation
CA3062845A1 (fr) 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systemes et methodes pour l'administration de medicaments par voie ophtalmique
CN110177527B (zh) 2016-08-12 2022-02-01 科尼尔赛德生物医学公司 用于调节药剂递送用针的***深度的装置和方法
CN111803623B (zh) * 2020-07-31 2024-07-02 重庆康视美科技有限公司 一种治疗近视的生物制剂及其制备方法、使用方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992002247A1 (fr) * 1990-08-01 1992-02-20 Chiron Ophthalmics, Inc. Methode de traitement des blessures endotheliales corneennes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992002247A1 (fr) * 1990-08-01 1992-02-20 Chiron Ophthalmics, Inc. Methode de traitement des blessures endotheliales corneennes

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CONNOR T.B. ET AL.: "Correlation of Fibrosis and Transforming Growth Factor-beta Type 2 Levels in the Eye", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 85, no. 5, pages 1661 - 1666, XP002047092, DOI: doi:10.1172/JCI114065 *
JAMPEL H D ET AL: "TRANSFORMING GROWTH FACTOR -BETA IN HUMAN AQUEOUS HUMOR.", CURR EYE RES 9 (10). 1990. 963-970. *
See also references of WO9401124A1 *
TRIPATHI R C ET AL: "Role of Growth Factors in the Uveal Tract of the Eye as Targeted to the Development of Nw Drugs", DRUG DEV RES 23(1). 1991. 1-25. *

Also Published As

Publication number Publication date
WO1994001124A1 (fr) 1994-01-20
EP0651650A1 (fr) 1995-05-10
AU4668193A (en) 1994-01-31
CA2138644A1 (fr) 1994-01-20
JPH08502033A (ja) 1996-03-05

Similar Documents

Publication Publication Date Title
EP0651650A4 (fr) PROCEDE POUR TRAITER DES AFFECTIONS OPHTALMIQUES A L'AIDE DU FACTEUR TRANSFORMANT DE CROISSANCE--g(b).
EP0820467A4 (fr) Procedes de traitement de troubles oculaires
GB9304153D0 (en) Horizontal well treatment method
AU1935395A (en) Method for treating conditions of the eye using polypeptides
GB2233996B (en) Well treatment method
EP0729361A4 (fr) Procede de traitement de troubles neurologiques
EP0630383A4 (fr) Procedes de traitement des diabetes.
EP0493037A3 (en) Method of treating thromboembolic disorders
EP0610444A4 (fr) Procede de traitement de maladies virales.
ZA931063B (en) Treatment of glaucoma.
ZA965346B (en) Methods of treating neuropeptide Y-associated conditions.
EP0732938A4 (fr) Procede pour traiter des troubles intestinaux
GB9202196D0 (en) Method of treatment
ZA9010081B (en) Method for the treatment of glaucoma
EP0608702A3 (fr) Procédé de traitement des noisettes.
GB9201391D0 (en) Method of treatment
AU2269392A (en) Method for treating immunological disorders and diseases
AU2321088A (en) Method for preventing or treating thrombocytopenia
RU1785687C (ru) Cпocoб лeчehия глoccaлгии
GB9223953D0 (en) Treatment of eye disorders
GB9223252D0 (en) Method of treatment
GB9202698D0 (en) Method of treatment
GB9218188D0 (en) Method of treatment
ZA963472B (en) Method of treatment.
IL100629A0 (en) Apparatus for the treatment of papulosquamous disorders

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19950109

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

RHK1 Main classification (correction)

Ipc: A61K 38/00

RHK1 Main classification (correction)

Ipc: A61K 37/02

A4 Supplementary search report drawn up and despatched

Effective date: 19960304

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

17Q First examination report despatched

Effective date: 19980730

GRAG Despatch of communication of intention to grant

Free format text: ORIGINAL CODE: EPIDOS AGRA

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 19991211